JP2014523851A5 - - Google Patents

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Publication number
JP2014523851A5
JP2014523851A5 JP2013546480A JP2013546480A JP2014523851A5 JP 2014523851 A5 JP2014523851 A5 JP 2014523851A5 JP 2013546480 A JP2013546480 A JP 2013546480A JP 2013546480 A JP2013546480 A JP 2013546480A JP 2014523851 A5 JP2014523851 A5 JP 2014523851A5
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substituted
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alkyl group
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JP2013546480A
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JP5976011B2 (ja
JP2014523851A (ja
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JP2013546480A 2011-04-05 2012-04-05 スルホンアミド誘導体およびその用途 Active JP5976011B2 (ja)

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Application Number Priority Date Filing Date Title
JP2013546480A JP5976011B2 (ja) 2011-04-05 2012-04-05 スルホンアミド誘導体およびその用途

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2011084100 2011-04-05
JP2011084100 2011-04-05
JP2013546480A JP5976011B2 (ja) 2011-04-05 2012-04-05 スルホンアミド誘導体およびその用途
PCT/JP2012/059949 WO2012137982A2 (en) 2011-04-05 2012-04-05 Sulfonamide derivative and use thereof

Publications (3)

Publication Number Publication Date
JP2014523851A JP2014523851A (ja) 2014-09-18
JP2014523851A5 true JP2014523851A5 (https=) 2015-05-21
JP5976011B2 JP5976011B2 (ja) 2016-08-23

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JP2013546480A Active JP5976011B2 (ja) 2011-04-05 2012-04-05 スルホンアミド誘導体およびその用途

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US (1) US9527807B2 (https=)
EP (1) EP2694472B1 (https=)
JP (1) JP5976011B2 (https=)
WO (1) WO2012137982A2 (https=)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6134654B2 (ja) 2012-02-08 2017-05-24 武田薬品工業株式会社 複素環化合物およびその用途
JO3225B1 (ar) * 2012-11-27 2018-03-08 Lilly Co Eli 6-((s)-1-{1-[5-(2-هيدروكسي-إيثوكسي)-بيريدين-2-يل]-1h-بيرازول-3-يل}إيثيل)-3h-1 ، 3-بنزو ثيازول-2- أون باعتباره مضاد مستقبل ampa يعتمد على tarp- جاما 8
EP3122727B1 (en) 2014-03-24 2018-01-31 Bayer CropScience Aktiengesellschaft Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from alpha , alpha-dihaloamines and ketimines
EP3015458A1 (en) * 2014-11-03 2016-05-04 Bayer CropScience AG Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines
LT3984994T (lt) 2016-02-04 2024-10-10 Takeda Pharmaceutical Company Limited Pakeistas piperidino junginys kaip 2 tipo oreksino agonistas narkolepsijai gydyti
EP3436021A4 (en) 2016-03-29 2019-11-06 RespireRx Pharmaceuticals Inc. COMPOSITIONS AND METHODS FOR TREATING ATTENTION DEFICIT DISORDER
AR108838A1 (es) 2016-06-21 2018-10-03 Bristol Myers Squibb Co Ácidos de carbamoiloximetil triazol ciclohexilo como antagonistas de lpa
US11059780B2 (en) 2017-03-08 2021-07-13 Takeda Pharmaceutical Company Limited Substituted pyrrolidine compound and use thereof
JP7012703B2 (ja) 2017-03-08 2022-02-14 武田薬品工業株式会社 置換ピロリジン化合物およびその用途
WO2019027003A1 (ja) * 2017-08-03 2019-02-07 武田薬品工業株式会社 複素環化合物およびその用途
US10428023B2 (en) 2017-08-03 2019-10-01 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
EP3693360B1 (en) 2017-10-06 2023-12-13 Takeda Pharmaceutical Company Limited Heterocyclic compounds
ES2970624T3 (es) 2017-10-06 2024-05-29 Takeda Pharmaceuticals Co Compuesto heterocíclico
EP4011875A1 (en) 2017-12-19 2022-06-15 Bristol-Myers Squibb Company Triazole n-linked carbamoyl cyclohexyl acids as lpa antagonists
US11447475B2 (en) 2017-12-19 2022-09-20 Bristol-Myers Squibb Company Isoxazole N-linked carbamoyl cyclohexyl acids as LPA antagonists
US11180488B2 (en) 2017-12-19 2021-11-23 Bristol-Myers Squibb Company Isoxazole o-linked carbamoyl cyclohexyl acids as LPA antagonists
EA202091505A1 (ru) 2017-12-19 2020-09-22 Бристол-Маерс Сквибб Компани Триазолазолы циклогексильной кислоты в качестве антагонистов lpa
KR102756639B1 (ko) 2017-12-19 2025-01-16 브리스톨-마이어스 스큅 컴퍼니 Lpa 길항제로서의 시클로헥실 산 이속사졸 아졸
KR102777148B1 (ko) 2017-12-19 2025-03-05 브리스톨-마이어스 스큅 컴퍼니 Lpa 길항제로서의 시클로헥실 산 트리아졸 아진
EP3728209B1 (en) 2017-12-19 2025-12-24 Bristol-Myers Squibb Company Cyclohexyl acid isoxazole azines as lpa antagonists
EA039459B1 (ru) * 2017-12-25 2022-01-28 Такеда Фармасьютикал Компани Лимитед Гетероциклическое соединение и его применение в качестве средства для лечения заболеваний, связанных с рецептором орексина 2 типа
KR20200132858A (ko) * 2018-03-20 2020-11-25 에자이 알앤드디 매니지먼트 가부시키가이샤 간질 치료제
WO2020004537A1 (ja) 2018-06-29 2020-01-02 武田薬品工業株式会社 複素環化合物およびその用途
JP7339250B2 (ja) 2018-06-29 2023-09-05 武田薬品工業株式会社 複素環化合物およびその用途
US20220041572A1 (en) 2018-09-18 2022-02-10 Bristol-Myers Squibb Company Cycloheptyl acids as lpa antagonists
ES2946657T3 (es) 2018-09-18 2023-07-24 Bristol Myers Squibb Co Acidos ciclopentílicos como antagonistas de LPA
EP3896060B1 (en) 2018-12-12 2023-08-16 Takeda Pharmaceutical Company Limited Heterocyclic compound
US12071434B2 (en) 2018-12-12 2024-08-27 Takeda Pharmaceutical Company Limited Heterocyclic compound
JP7253640B2 (ja) * 2019-01-31 2023-04-06 武田薬品工業株式会社 複素環化合物およびその用途
US11098029B2 (en) 2019-02-13 2021-08-24 Merck Sharp & Dohme Corp. 5-alkyl pyrrolidine orexin receptor agonists
WO2020167701A1 (en) 2019-02-13 2020-08-20 Merck Sharp & Dohme Corp. Pyrrolidine orexin receptor agonists
CN114599648A (zh) 2019-06-18 2022-06-07 百时美施贵宝公司 作为lpa拮抗剂的三唑羧酸
EP3986553B1 (en) 2019-06-18 2026-03-25 Bristol-Myers Squibb Company Cyclobutyl carboxylic acids as lpa antagonists
KR20220024549A (ko) 2019-06-18 2022-03-03 브리스톨-마이어스 스큅 컴퍼니 Lpa 길항제로서의 이속사졸 카르복실산
US12312332B2 (en) 2019-08-08 2025-05-27 Merck Sharp & Dohme Llc Heteroaryl pyrrolidine and piperidine orexin receptor agonists
EP4065585B1 (en) 2019-11-25 2025-08-20 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment
US12448377B2 (en) 2019-11-27 2025-10-21 Takeda Pharmaceutical Company Limited Heterocyclic compound
BR112023002957A2 (pt) 2020-08-18 2023-04-04 Merck Sharp & Dohme Llc Composto, composição farmacêutica, e, métodos para tratar narcolepsia e para tratar hipersonia em um sujeito mamífero
US11760747B2 (en) * 2020-12-21 2023-09-19 Alkermes, Inc. Substituted piperidino compounds and related methods of treatment
US12006330B2 (en) 2020-12-21 2024-06-11 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment
IL315808A (en) 2022-03-28 2024-11-01 Bayer Ag Process for preparing cis-4-aminotetrahydrofuran-2-carboxylic esters
WO2023199091A1 (en) 2022-04-12 2023-10-19 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2023249871A1 (en) * 2022-06-21 2023-12-28 Alkermes, Inc. Substituted pyrrolidinyl and piperidinyl compounds and related methods of treatment
JP2025521507A (ja) * 2022-06-21 2025-07-10 アルカームス インコーポレーテッド 置換縮合二環式化合物および関連する治療方法
CA3260225A1 (en) * 2022-06-21 2023-12-28 Alkermes, Inc. Fused, Substituted Bicyclic Compounds and Associated Treatment Methods
TW202409023A (zh) 2022-07-14 2024-03-01 美商富曼西公司 除草苯并𠯤
CN115433102B (zh) * 2022-10-16 2024-02-27 大连双硼医药化工有限公司 一种反式-(1r,2r)-2-氨基环己烷羧酸乙酯盐酸盐的制备方法
TW202428580A (zh) 2022-10-31 2024-07-16 日商武田藥品工業股份有限公司 雜環化合物
AR131202A1 (es) 2022-11-30 2025-02-26 Takeda Pharmaceuticals Co Compuesto heterocíclico y uso del mismo
PE20252742A1 (es) 2023-03-16 2025-12-05 Takeda Pharmaceuticals Co Compuestos heterociclicos macrociclicos y sus usos
WO2025111184A1 (en) 2023-11-21 2025-05-30 Fmc Corporation Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides
WO2025229494A1 (en) 2024-04-29 2025-11-06 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2025229495A1 (en) 2024-04-29 2025-11-06 Takeda Pharmaceutical Company Limited Heterocyclic compound

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2765322A (en) 1953-03-03 1956-10-02 Rohm & Haas Preparation of bis(4-glycidyloxyphenyl)-sulfone
US5315013A (en) 1988-01-07 1994-05-24 E. I. Du Pont De Nemours And Company Substituted pyrazole angiotensin II antagonists
KR100338855B1 (ko) 1996-07-31 2002-12-28 시오노기세이야쿠가부시키가이샤 신규 파라테르페닐 화합물
DE19803396A1 (de) 1998-01-29 1999-08-05 Bayer Ag Substituierte Phenyluracile
US6902847B1 (en) 1998-05-20 2005-06-07 Osaka Gas Company Limited Non-aqueous secondary cell and method for controlling the same
ES2230864T3 (es) * 1998-07-24 2005-05-01 Teijin Limited Derivados del acido antranilico.
BR0012068A (pt) 1999-06-30 2002-05-14 Daiichi Seiyaku Co Compostos inibidores de vla-4
TWI262917B (en) 2002-02-01 2006-10-01 Dainippon Sumitomo Pharma Co 2-Furancarboxylic hydrazides and pharmaceutical compositions containing the same
JP2003238538A (ja) 2002-02-12 2003-08-27 Nippon Nohyaku Co Ltd 新規4−置換フェニル−5−ハロピリミジン誘導体及びこれを有効成分とする除草剤
JP2005060385A (ja) 2003-07-31 2005-03-10 Dainippon Pharmaceut Co Ltd 2−フランカルボン酸ヒドラジド化合物からなる医薬
GB0417709D0 (en) 2004-08-09 2004-09-08 Glaxo Group Ltd Compounds
WO2006015827A1 (en) 2004-08-09 2006-02-16 Glaxo Group Limited Compounds which potentiate glutamate receptor and uses thereof in medicine
KR20070050070A (ko) 2004-08-09 2007-05-14 글락소 그룹 리미티드 글루타메이트 수용체를 강화시키는 화합물 및 의약에서의그의 용도
EP1849465A4 (en) 2005-02-18 2008-12-24 Takeda Pharmaceutical AGENS TO CONTROL THE FUNCTION OF THE GPR34 RECEPTOR
UA92007C2 (ru) 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности
DE602006003661D1 (de) 2005-06-06 2008-12-24 Lilly Co Eli Ampa-rezeptoren-verstärker
AU2006265639A1 (en) 2005-07-01 2007-01-11 Jenrin Discovery MAO-B inhibitors useful for treating obesity
JP5014334B2 (ja) * 2005-10-06 2012-08-29 イーライ リリー アンド カンパニー Ampa受容体増強剤
JP2010517926A (ja) 2006-02-08 2010-05-27 グラクソ グループ リミテッド グルタミン酸受容体を増強する、統合失調症の治療に有用な4−フェニル−3−(2−プロピルスルホニルアミノ)テトラヒドロフラン誘導体
GB0602560D0 (en) 2006-02-08 2006-03-22 Glaxo Group Ltd Compounds
US8097652B2 (en) 2006-12-11 2012-01-17 Eli Lilly And Company AMPA receptor potentiators
WO2008113795A1 (en) 2007-03-20 2008-09-25 Glaxo Group Limited Compounds which potentiate ampa receptor and uses thereof in medicine
EP2142505A1 (en) 2007-04-03 2010-01-13 Pfizer, Inc. Sulfonamides and pharmaceutical compositions thereof
AR069781A1 (es) 2007-12-19 2010-02-17 Glaxo Group Ltd Compuestos de n-(2,3-dihidro-inden-2-il) propanosulfonamida, composicion farmaceutica que los comprenden y su uso para el tratamiento de la ezquizofrenia.
GB0801265D0 (en) 2008-01-23 2008-02-27 Glaxo Group Ltd Compounds
GB0801220D0 (en) 2008-01-23 2008-02-27 Glaxo Group Ltd Compounds
WO2009119088A1 (ja) 2008-03-25 2009-10-01 武田薬品工業株式会社 複素環化合物
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
CA2739559A1 (en) 2008-10-08 2010-04-15 Pfizer Inc. Tetrahydrofuranyl sulfonamides and pharmaceutical compositions thereof
EP2417101B1 (en) * 2009-04-09 2013-10-23 Merck Sharp & Dohme B.V. Indane derivatives
AP3066A (en) * 2009-06-26 2014-12-31 Pfizer Heterocyclic sulfonamides, uses and pharmaceuticalcompositions thereof
RU2012106426A (ru) 2009-07-23 2013-08-27 Новартис Аг 1н-хиназолин-2,4-дионы, предназначенные для лечения нейронного восковидного липофусциноза
LT2603513T (lt) 2010-08-10 2020-05-25 Takeda Pharmaceutical Company Limited Heterociklinis junginys ir jo panaudojimas kaip ampa receptoriaus teigiamo alosterinio moduliatoriaus

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