|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
SE9102074D0
(sv)
|
1991-07-03 |
1991-07-03 |
Kabi Pharmacia Ab |
Tomour antigen specific antibody
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
EP0563475B1
(en)
|
1992-03-25 |
2000-05-31 |
Immunogen Inc |
Cell binding agent conjugates of derivatives of CC-1065
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
IL111748A0
(en)
|
1993-12-03 |
1995-01-24 |
Zeneca Ltd |
Proteins
|
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5958872A
(en)
|
1996-04-01 |
1999-09-28 |
Apoptosis Technology, Inc. |
Active survival domains of IGF-IR and methods of use
|
|
WO1999006587A2
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
TW593241B
(en)
|
1999-04-20 |
2004-06-21 |
Hoffmann La Roche |
Carbamic acid derivatives
|
|
WO2001058479A1
(en)
|
2000-02-08 |
2001-08-16 |
The Penn State Research Foundation |
Immunotherapy using interleukin 13 receptor subunit alpha 2
|
|
US6596503B1
(en)
|
2000-08-18 |
2003-07-22 |
East Carolina University |
Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
NZ527302A
(en)
|
2001-01-05 |
2006-10-27 |
Abgenix Inc |
Antibodies to insulin-like growth factor I receptor
|
|
DK1578446T3
(en)
|
2002-11-07 |
2015-06-29 |
Immunogen Inc |
ANTI-CD33 ANTIBODIES AND PROCEDURES FOR TREATING ACUTE MYELOID LEUKEMIA BY USING IT
|
|
MXPA05014155A
(es)
|
2003-06-27 |
2006-05-25 |
Abgenix Inc |
Anticuerpos dirigidos a los mutantes de delecion de receptor de factor de crecimiento epidermico y sus usos.
|
|
NZ551180A
(en)
|
2004-06-01 |
2009-10-30 |
Genentech Inc |
Antibody drug conjugates and methods
|
|
AU2004224925C1
(en)
|
2004-08-30 |
2011-07-21 |
Biotest Ag |
Immunoconjugates targeting syndecan-1 expressing cells and use thereof
|
|
US20080305044A1
(en)
|
2004-11-29 |
2008-12-11 |
Seattle Genetics, Inc. |
Engineered Antibodies and Immunoconjugates
|
|
KR101281501B1
(ko)
|
2004-12-09 |
2013-07-15 |
얀센 바이오테크 인코포레이티드 |
항인테그린 면역 컨쥬게이트, 방법 및 용도
|
|
WO2006096653A2
(en)
|
2005-03-04 |
2006-09-14 |
Biogen Idec Ma Inc. |
Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
US8399219B2
(en)
|
2009-02-23 |
2013-03-19 |
Cytomx Therapeutics, Inc. |
Protease activatable interferon alpha proprotein
|
|
AR076284A1
(es)
|
2009-04-29 |
2011-06-01 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
|
UY32914A
(es)
|
2009-10-02 |
2011-04-29 |
Sanofi Aventis |
Anticuerpos que se usan específicamente al receptor epha2
|
|
UY32913A
(es)
|
2009-10-02 |
2011-04-29 |
Sanofi Aventis |
Nuevos maitansinoides y el uso de dichos maitansinoides para preparar conjugados con un anticuero
|
|
CN105777907B
(zh)
|
2010-02-24 |
2020-03-17 |
伊缪诺金公司 |
叶酸受体1抗体与免疫缀合物以及其用途
|
|
LT2544719T
(lt)
|
2010-03-12 |
2019-10-25 |
Debiopharm Int Sa |
Cd37 surišančios molekulės, ir jų imunokonjugatai
|
|
WO2012019024A2
(en)
|
2010-08-04 |
2012-02-09 |
Immunogen, Inc. |
Her3-binding molecules and immunoconjugates thereof
|
|
US9090629B2
(en)
|
2010-11-03 |
2015-07-28 |
Immunogen, Inc. |
Cytotoxic agents comprising new ansamitocin derivatives
|
|
WO2012095347A1
(en)
|
2011-01-10 |
2012-07-19 |
Technische Universität München |
Triazacyclononane-based phosphinate ligand and its use for molecular imaging
|
|
SI2675480T1
(sl)
*
|
2011-02-15 |
2019-05-31 |
Immunogen, Inc. |
Metode priprave konjugatov
|
|
EA033468B1
(ru)
*
|
2011-03-29 |
2019-10-31 |
Immunogen Inc |
Способы получения конъюгата "антитело-майтансиноид"
|
|
WO2012177837A2
(en)
*
|
2011-06-21 |
2012-12-27 |
Immunogen, Inc. |
Novel maytansinoid derivatives with peptide linker and conjugates thereof
|
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|