JP2019505185A5 - - Google Patents

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Publication number
JP2019505185A5
JP2019505185A5 JP2018531159A JP2018531159A JP2019505185A5 JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5 JP 2018531159 A JP2018531159 A JP 2018531159A JP 2018531159 A JP2018531159 A JP 2018531159A JP 2019505185 A5 JP2019505185 A5 JP 2019505185A5
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JP
Japan
Prior art keywords
hmwk
sample
hae
peptide
seq
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JP2018531159A
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English (en)
Japanese (ja)
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JP7092669B2 (ja
JP2019505185A (ja
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Priority claimed from PCT/US2016/066936 external-priority patent/WO2017106504A1/en
Publication of JP2019505185A publication Critical patent/JP2019505185A/ja
Publication of JP2019505185A5 publication Critical patent/JP2019505185A5/ja
Priority to JP2022096962A priority Critical patent/JP7425117B2/ja
Application granted granted Critical
Publication of JP7092669B2 publication Critical patent/JP7092669B2/ja
Priority to JP2024005910A priority patent/JP7758766B2/ja
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JP2018531159A 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ Active JP7092669B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022096962A JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562267734P 2015-12-15 2015-12-15
US62/267,734 2015-12-15
PCT/US2016/066936 WO2017106504A1 (en) 2015-12-15 2016-12-15 Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk

Related Child Applications (1)

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JP2022096962A Division JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Publications (3)

Publication Number Publication Date
JP2019505185A JP2019505185A (ja) 2019-02-28
JP2019505185A5 true JP2019505185A5 (enExample) 2020-01-30
JP7092669B2 JP7092669B2 (ja) 2022-06-28

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ID=57794352

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018531159A Active JP7092669B2 (ja) 2015-12-15 2016-12-15 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022096962A Active JP7425117B2 (ja) 2015-12-15 2022-06-16 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ
JP2024005910A Active JP7758766B2 (ja) 2015-12-15 2024-01-18 完全長の高分子量キニノーゲン(hmwk)と切断されたhmwkとを区別するためのペプチド定量アッセイ

Country Status (13)

Country Link
US (3) US11668718B2 (enExample)
EP (2) EP3390439B1 (enExample)
JP (3) JP7092669B2 (enExample)
KR (2) KR102874711B1 (enExample)
CN (1) CN108602877A (enExample)
AU (3) AU2016372159B2 (enExample)
CA (1) CA3008621A1 (enExample)
CO (1) CO2018007216A2 (enExample)
EA (1) EA201891414A1 (enExample)
IL (4) IL297850B2 (enExample)
MX (2) MX2018007493A (enExample)
NZ (1) NZ743482A (enExample)
WO (1) WO2017106504A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3060908T (pt) 2013-10-21 2021-05-27 Dyax Corp Diagnóstico e tratamento de doenças autoimunes
KR20250066486A (ko) 2013-10-21 2025-05-13 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 시스템 바이오마커를 결정하기 위한 검정법
JP6903648B2 (ja) 2015-10-19 2021-07-14 ダイアックス コーポレーション 切断高分子量キニノーゲンを検出するイムノアッセイ
EP3390439B1 (en) 2015-12-15 2025-03-12 Takeda Pharmaceutical Company Limited Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk
WO2018225830A1 (ja) * 2017-06-08 2018-12-13 国立大学法人宮崎大学 肺がんの検出方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047323A (en) * 1986-01-22 1991-09-10 Temple University Of The Commonwealth System Of Higher Education Method for detecting human kininogen using monoclonal antibodies thereto
JP2603487B2 (ja) 1987-11-26 1997-04-23 大日本製薬株式会社 ガンに罹患している疑いのあるヒトをスクリーニングする方法
JPH08208692A (ja) 1994-09-28 1996-08-13 Sumitomo Pharmaceut Co Ltd 新規な細胞接着抑制ペプチド誘導体
JP3073439B2 (ja) * 1996-02-08 2000-08-07 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
AU1521500A (en) 1998-11-10 2000-05-29 W. Robert Colman Inhibition of angiogenesis by peptide analogs of high molecular weight kininogendomain
US20060154319A1 (en) 1999-04-29 2006-07-13 Flodgaard Hans J Inhibition of bradykinin release
WO2001034195A1 (en) 1999-11-12 2001-05-17 Temple University Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
CA2478962A1 (en) 2002-03-15 2003-09-25 Attenuon, Llc Cell surface tropomyosin as a target of angiogenesis inhibition
CN1858243A (zh) 2005-04-30 2006-11-08 安徽省生物医学研究所 一种预测血管紧张素ii受体拮抗剂类降压药药物作用的方法及其应用
EP2216651A4 (en) * 2007-10-18 2010-12-01 Miyazaki Prefectural Ind Suppo BIOMARKERS FOR THE DIAGNOSIS OF LIVER DISEASE
JP5348595B2 (ja) 2008-07-07 2013-11-20 日本臓器製薬株式会社 線維筋痛症の検査法
GB0821721D0 (en) 2008-11-27 2008-12-31 Hansa Medical Ab Antimicrobial therapy
DK3173792T3 (da) 2009-03-30 2019-08-05 Novartis Ag Crp neo-epitop fibrose-assay
JP5714285B2 (ja) 2010-09-29 2015-05-07 株式会社プロトセラ 妊娠高血圧症候群マーカーおよびそれを用いた診断
CN102558329A (zh) 2010-12-10 2012-07-11 中国人民解放军军事医学科学院生物医学分析中心 一组特异性多肽及其在制备肺癌早期诊断试剂中的用途
LT2831113T (lt) 2012-03-28 2018-06-25 Sanofi Antikūnai prieš bradikinino b1 receptoriaus ligandus
CN111044725B (zh) * 2013-01-20 2024-03-29 武田药品工业株式会社 缓激肽介导的病症的评估和治疗
JP2016188761A (ja) 2013-08-23 2016-11-04 国立研究開発法人国立国際医療研究センター 糖尿病腎症の発症または発症リスクの検出方法及びキット
KR20250066486A (ko) * 2013-10-21 2025-05-13 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 시스템 바이오마커를 결정하기 위한 검정법
WO2015120036A1 (en) * 2014-02-04 2015-08-13 University Of Virginia Patent Foundation Compositions and methods for analysis of protein sequences and post-translational modifications
CN104155457B (zh) 2014-08-22 2016-11-16 北京蛋白质组研究中心 一种结直肠癌相关“多肽-蛋白组合式标志物”检测试剂盒
CN104345154B (zh) 2014-08-22 2016-10-26 北京蛋白质组研究中心 一种检测多肿瘤相关“多肽-蛋白组合式标志物”的双抗体夹心试剂盒
WO2016081413A1 (en) * 2014-11-17 2016-05-26 The Rockefeller University Compositions and methods for use in diagnosis of alzheimer's disease
EP3390439B1 (en) 2015-12-15 2025-03-12 Takeda Pharmaceutical Company Limited Peptide quantitation assay for differentiating full-length high molecular weight kininogen (hmwk) and cleaved hmwk

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