|
GB335768A
(en)
|
1929-10-24 |
1930-10-02 |
Jacoviac Maurice |
Improvements in protecting devices for gramophone disc records
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
SE509359C2
(sv)
|
1989-08-01 |
1999-01-18 |
Cemu Bioteknik Ab |
Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
|
|
AU701578B2
(en)
|
1992-08-21 |
1999-02-04 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
WO1994025591A1
(en)
|
1993-04-29 |
1994-11-10 |
Unilever N.V. |
PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE)
|
|
FR2708622B1
(fr)
|
1993-08-02 |
1997-04-18 |
Raymond Hamers |
Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
|
|
EP0739981A1
(en)
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
ES2294799T3
(es)
|
1996-06-27 |
2008-04-01 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. |
Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
|
|
US6329516B1
(en)
|
1997-04-28 |
2001-12-11 |
Fmc Corporation |
Lepidopteran GABA-gated chloride channels
|
|
BR9813276A
(pt)
|
1997-10-27 |
2000-08-22 |
Unilever Nv |
Proteìna multivalente de ligação de antìgeno, sequências de nucleotìdeos, vetor de expressão, célula hospedeira, processo para preparação de proteìna multivalente de ligação de antìgeno, e, uso da mesma
|
|
WO1999037681A2
(en)
|
1998-01-26 |
1999-07-29 |
Unilever Plc |
Method for producing antibody fragments
|
|
AU3295299A
(en)
|
1998-02-19 |
1999-09-06 |
Xcyte Therapies, Inc. |
Compositions and methods for regulating lymphocyte activation
|
|
EP0967284A1
(en)
|
1998-05-28 |
1999-12-29 |
Pfizer Limited |
Phosphodiesterases
|
|
BR9916765A
(pt)
|
1999-01-05 |
2001-09-25 |
Unilever Nv |
Processo para produzir um material imunoadsorvente, uso de uma proteìna que é ligada por meio de uma ligação covalente a um fragmento de anticorpo, material imunadsorvente, uso de um material, e, kit de teste diagnóstico
|
|
DE60013767T3
(de)
|
1999-01-19 |
2009-07-09 |
Unilever N.V. |
Verfahren zur herstellung von antikörperfragmenten
|
|
CA2361678A1
(en)
|
1999-02-05 |
2000-08-10 |
Rijksuniversiteit Leiden |
Method of modulating metabolite biosynthesis in recombinant cells
|
|
US6617122B1
(en)
|
1999-03-15 |
2003-09-09 |
Xenon Genetics, Inc. |
Process for identifying modulators of ABC1 activity
|
|
CN1252264C
(zh)
|
1999-04-22 |
2006-04-19 |
荷兰联合利华有限公司 |
利用单价抗原－结合蛋白抑制病毒感染
|
|
SG121853A1
(en)
|
1999-06-18 |
2006-05-26 |
Cv Therapeutics Inc |
Compositions and methods for increasing cholesterol efflux and raising hdl using atp binding cassette transporter protein abc1
|
|
EP1198572A2
(en)
|
1999-08-02 |
2002-04-24 |
Keygene N.V. |
Method for generating cgmmv resistant plants, genetic constructs, and obtained cgmmv-resistant plants
|
|
GB9922124D0
(en)
|
1999-09-17 |
1999-11-17 |
Pfizer Ltd |
Phosphodiesterase enzymes
|
|
US6479280B1
(en)
|
1999-09-24 |
2002-11-12 |
Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw |
Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
|
|
DE19955408A1
(de)
|
1999-11-18 |
2001-05-23 |
Bayer Ag |
GABA-B-Rezeptoren
|
|
DE60042789D1
(de)
|
1999-11-29 |
2009-10-01 |
Bac Ip B V |
Immobilisierte antigenbindende moleküle aus einer domäne
|
|
AU1859201A
(en)
|
1999-11-29 |
2001-06-12 |
Unilever Plc |
Immobilisation of proteins
|
|
EP2180054A1
(en)
|
1999-12-24 |
2010-04-28 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
ES2324280T3
(es)
|
2000-03-14 |
2009-08-04 |
Unilever N.V. |
Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.
|
|
GB0006398D0
(en)
|
2000-03-16 |
2000-05-03 |
Novartis Ag |
Organic compounds
|
|
WO2001090190A2
(en)
|
2000-05-26 |
2001-11-29 |
National Research Council Of Canada |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
|
ATE513854T1
(de)
|
2000-12-13 |
2011-07-15 |
Bac Ip B V |
Proteinraster aus variablen domänen der schweren immunoglobulinkette von kamelen
|
|
US7211395B2
(en)
|
2001-03-09 |
2007-05-01 |
Dyax Corp. |
Serum albumin binding moieties
|
|
DK1399484T3
(da)
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
|
US20060073141A1
(en)
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
|
EP1433793A4
(en)
|
2001-09-13 |
2006-01-25 |
Inst Antibodies Co Ltd |
METHOD FOR CREATING A CAMEL ANTIBODY LIBRARY
|
|
JP2005289809A
(ja)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
EP1456410A2
(en)
|
2001-12-11 |
2004-09-15 |
AlgoNomics N.V. |
Method for displaying loops from immunoglobulin domains in different contexts
|
|
EP1456237A2
(en)
|
2001-12-21 |
2004-09-15 |
Vlaams Interuniversitair Instituut voor Biotechnologie vzw. |
Method for cloning of variable domain sequences
|
|
WO2003055527A2
(en)
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
US7521543B2
(en)
|
2002-10-23 |
2009-04-21 |
Ludwig Institute For Cancer Research |
A34 and A33-like 3 DNA, proteins, antibodies thereto and methods of treatment using same
|
|
WO2004041867A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Camelidae antibodies against imminoglobulin e and use thereof for the treatment of allergic disorders
|
|
WO2005044858A1
(en)
|
2003-11-07 |
2005-05-19 |
Ablynx N.V. |
Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
|
|
CA2505316C
(en)
|
2002-11-08 |
2014-08-05 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
EP1587838B1
(en)
|
2003-01-10 |
2015-04-15 |
Ablynx N.V. |
Therapeutic polypeptides, homologues thereof, fragments thereof and their use in modulating platelet-mediated aggregation
|
|
US7461263B2
(en)
|
2003-01-23 |
2008-12-02 |
Unspam, Llc. |
Method and apparatus for a non-revealing do-not-contact list system
|
|
AU2003264053A1
(en)
|
2003-08-12 |
2005-03-10 |
William M. Yarbrough |
Treatment for acne vulgaris and method of use
|
|
US7563443B2
(en)
*
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
WO2006040153A2
(en)
|
2004-10-13 |
2006-04-20 |
Ablynx N.V. |
Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
|
|
AU2005325801A1
(en)
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
|
WO2006122787A1
(en)
*
|
2005-05-18 |
2006-11-23 |
Ablynx Nv |
Serum albumin binding proteins
|
|
ES2852423T3
(es)
|
2005-05-20 |
2021-09-13 |
Ablynx Nv |
NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación
|
|
EP2057191A1
(en)
|
2006-08-18 |
2009-05-13 |
Ablynx N.V. |
Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
|
|
CA2671581A1
(en)
|
2006-12-05 |
2008-06-12 |
Ablynx N.V. |
Peptides capable of binding to serum proteins
|
|
JP2010518839A
(ja)
|
2007-02-21 |
2010-06-03 |
アブリンクス エン．ヴェー． |
血管内皮増殖因子に指向性を有するアミノ酸配列、及び過度の及び／もしくは病的な血管形成又は血管新生を特徴とする症状及び疾患を治療するためにこれを含むポリペプチド
|
|
PT2125894T
(pt)
|
2007-03-22 |
2019-02-27 |
Biogen Ma Inc |
Proteínas de ligação incluindo anticorpos, derivados de anticorpos e fragmentos de anticorpos que se ligam especificamente ao cd154 e as suas utilizações
|
|
CN101796072B
(zh)
|
2007-05-24 |
2014-09-24 |
埃博灵克斯股份有限公司 |
用于治疗骨疾病和病症的针对rank-l的氨基酸序列以及包括其的多肽
|
|
EP2268668A1
(en)
|
2008-04-17 |
2011-01-05 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
|
BRPI0913366A8
(pt)
*
|
2008-06-03 |
2017-07-11 |
Abbott Lab |
Imunoglobulinas de domínio variável duplo e seus usos
|
|
EP2513145B1
(en)
*
|
2009-12-14 |
2018-01-24 |
Ablynx N.V. |
Single variable domain antibodies against ox40l, constructs and therapeutic use
|
|
WO2012088302A2
(en)
*
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Half immunoglobulin binding proteins and uses thereof
|
|
CN106046168A
(zh)
|
2011-06-23 |
2016-10-26 |
埃博灵克斯股份有限公司 |
结合血清白蛋白的蛋白
|
|
DK2723769T4
(da)
|
2011-06-23 |
2022-09-05 |
Ablynx Nv |
Teknikker til at forudsige, påvise og reducere uspecifik proteininterferens i assays, som involverer variable immunglobulin-enkeltdomæner
|
|
SG2014010482A
(en)
|
2011-08-17 |
2014-04-28 |
Glaxo Group Ltd |
Modified proteins and peptides
|
|
SMT202000091T1
(it)
*
|
2011-10-13 |
2020-05-08 |
Bristol Myers Squibb Co |
Polipeptidi anticorpali che antagonizzano cd40l
|
|
CN105814082A
(zh)
|
2013-09-26 |
2016-07-27 |
埃博灵克斯股份有限公司 |
双特异性纳米抗体
|
|
EA201691634A1
(ru)
|
2014-03-19 |
2016-11-30 |
Бристол-Маерс Сквибб Компани |
Способы лечения отторжения трансплантата с использованием доменного антитела, направленного против cd40l
|
|
IL256800B2
(en)
|
2015-07-14 |
2023-04-01 |
Immunext Inc |
An anti-cd154 antibody with improved binding, functional and safety properties and use in human immunotherapy
|
|
PE20180802A1
(es)
|
2015-08-05 |
2018-05-09 |
Janssen Biotech Inc |
Anticuerpos anti-cd154 y metodos de uso de estos
|