JP2019503365A5 - - Google Patents
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- JP2019503365A5 JP2019503365A5 JP2018533135A JP2018533135A JP2019503365A5 JP 2019503365 A5 JP2019503365 A5 JP 2019503365A5 JP 2018533135 A JP2018533135 A JP 2018533135A JP 2018533135 A JP2018533135 A JP 2018533135A JP 2019503365 A5 JP2019503365 A5 JP 2019503365A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cells
- receptor antagonist
- administered
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1ccc(-c2nc(*)nc3c2nn[n]3Cc2nc(C[U]C3C[U]CC3)ccc2)[n]1 Chemical compound Cc1ccc(-c2nc(*)nc3c2nn[n]3Cc2nc(C[U]C3C[U]CC3)ccc2)[n]1 0.000 description 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562387383P | 2015-12-24 | 2015-12-24 | |
| US62/387,383 | 2015-12-24 | ||
| US201662324211P | 2016-04-18 | 2016-04-18 | |
| US62/324,211 | 2016-04-18 | ||
| US201662350602P | 2016-06-15 | 2016-06-15 | |
| US62/350,602 | 2016-06-15 | ||
| US201662421109P | 2016-11-11 | 2016-11-11 | |
| US201662421171P | 2016-11-11 | 2016-11-11 | |
| US62/421,171 | 2016-11-11 | ||
| US62/421,109 | 2016-11-11 | ||
| PCT/US2016/068459 WO2017112917A1 (en) | 2015-12-24 | 2016-12-22 | Methods of treating cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019503365A JP2019503365A (ja) | 2019-02-07 |
| JP2019503365A5 true JP2019503365A5 (enExample) | 2020-06-11 |
| JP6847958B2 JP6847958B2 (ja) | 2021-03-24 |
Family
ID=59091273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018533135A Active JP6847958B2 (ja) | 2015-12-24 | 2016-12-22 | がんの治療方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10912776B2 (enExample) |
| EP (1) | EP3393475B1 (enExample) |
| JP (1) | JP6847958B2 (enExample) |
| KR (1) | KR20180103918A (enExample) |
| CN (1) | CN108883107A (enExample) |
| AU (1) | AU2016379425B2 (enExample) |
| CA (1) | CA3009527C (enExample) |
| EA (1) | EA201891509A1 (enExample) |
| ES (1) | ES3017686T3 (enExample) |
| IL (1) | IL260199B (enExample) |
| MX (1) | MX391382B (enExample) |
| WO (1) | WO2017112917A1 (enExample) |
| ZA (1) | ZA201804227B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016379425B2 (en) * | 2015-12-24 | 2021-11-11 | Corvus Pharmaceuticals, Inc. | Methods of treating cancer |
| WO2018187484A1 (en) | 2017-04-04 | 2018-10-11 | Corvus Pharmaceuticals, Inc. | Methods of treating cancer |
| CA3070073A1 (en) | 2017-07-18 | 2019-01-24 | Nuvation Bio Inc. | 1,8-naphthyridinone compounds and uses thereof |
| JP2020527588A (ja) | 2017-07-18 | 2020-09-10 | ニューベイション・バイオ・インコーポレイテッドＮｕｖａｔｉｏｎ Ｂｉｏ Ｉｎｃ． | アデノシンアンタゴニストとしてのヘテロ環式化合物 |
| CN109293652B (zh) * | 2017-07-24 | 2021-10-22 | 四川科伦博泰生物医药股份有限公司 | 一种取代的噻唑衍生物及其用途 |
| US10702476B2 (en) * | 2017-08-14 | 2020-07-07 | Phosphorex, Inc. | Microparticle formulations of adenosine receptor antagonists for treating cancer |
| CN109662966A (zh) * | 2017-10-16 | 2019-04-23 | 北京莱科金基因科技有限责任公司 | 伊曲茶碱在制备用于肿瘤治疗的药物中的用途 |
| EP3706752A4 (en) * | 2017-11-06 | 2021-12-15 | Corvus Pharmaceuticals, Inc. | COMBINATORY THERAPY FOR ANTI-CANCER TREATMENT |
| CA3080976A1 (en) * | 2017-11-06 | 2019-05-09 | Corvus Pharmaceuticals, Inc. | Adenosine pathway inhibitors for cancer treatment |
| CN111615389A (zh) * | 2018-02-01 | 2020-09-01 | 科尔沃斯制药股份有限公司 | 药物调配物 |
| EP3520782A3 (en) | 2018-02-01 | 2019-11-13 | Corvus Pharmaceuticals, Inc. | Pharmaceutical formulations containing adenosine a2a receptor antagonists |
| AU2019227607C1 (en) | 2018-02-27 | 2023-07-20 | Incyte Corporation | Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors |
| EP3810610A1 (en) | 2018-05-18 | 2021-04-28 | Incyte Corporation | Fused pyrimidine derivatives as a2a / a2b inhibitors |
| WO2019233994A1 (en) | 2018-06-04 | 2019-12-12 | Exscientia Ltd | Pyrazolopyrimidine compounds as adenosine receptor antagonists |
| CN117304191A (zh) | 2018-07-05 | 2023-12-29 | 因赛特公司 | 作为a2a/a2b抑制剂的稠合吡嗪衍生物 |
| WO2020014666A1 (en) * | 2018-07-12 | 2020-01-16 | Corvus Pharmaceuticals, Inc. | Methods for detecting and treating cancers having adenosine pathway activation |
| KR102767594B1 (ko) | 2018-07-12 | 2025-02-12 | 코버스 파마슈티칼스, 인크. | 아데노신 경로 활성화를 갖는 암의 검출 및 치료 방법 |
| WO2020146795A1 (en) | 2019-01-11 | 2020-07-16 | Omeros Corporation | Methods and compositions for treating cancer |
| US11254670B2 (en) | 2019-01-18 | 2022-02-22 | Nuvation Bio Inc. | 1,8-naphthyridinone compounds and uses thereof |
| WO2020150674A1 (en) | 2019-01-18 | 2020-07-23 | Nuvation Bio Inc. | Heterocyclic compounds as adenosine antagonists |
| TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
| KR20200105246A (ko) * | 2019-02-28 | 2020-09-07 | 한미약품 주식회사 | 아데노신 수용체 길항제로서 신규 화합물 및 이를 포함하는 약학 조성물 |
| CN112608316B (zh) * | 2019-07-30 | 2022-10-21 | 厦门宝太生物科技股份有限公司 | 一种吡唑并三嗪类腺苷受体拮抗剂 |
| CA3161177A1 (en) * | 2019-11-26 | 2021-06-03 | Astrazeneca Ab | Methods of treating cancer |
| AU2020400030B2 (en) * | 2019-12-09 | 2026-05-21 | Twist Bioscience Corporation | Variant nucleic acid libraries for adenosine receptors |
| CN115279766B (zh) * | 2020-01-03 | 2025-05-02 | 因赛特公司 | 包含a2a/a2b和pd-1/pd-l1抑制剂的组合疗法 |
| WO2022159620A1 (en) * | 2021-01-21 | 2022-07-28 | Twist Bioscience Corporation | Methods and compositions relating to adenosine receptors |
| CN116898858B (zh) * | 2023-08-11 | 2025-09-23 | 锦州医科大学 | 一种治疗非小细胞肺癌的药物 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP0739904A1 (en) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispecific reagents for aids therapy |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| AU8295491A (en) | 1990-06-29 | 1992-01-23 | Biosource Technologies Incorporated | Melanin production by transformed microorganisms |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| US5777085A (en) | 1991-12-20 | 1998-07-07 | Protein Design Labs, Inc. | Humanized antibodies reactive with GPIIB/IIIA |
| US6210671B1 (en) | 1992-12-01 | 2001-04-03 | Protein Design Labs, Inc. | Humanized antibodies reactive with L-selectin |
| WO2000032634A1 (en) | 1998-12-01 | 2000-06-08 | Protein Design Labs, Inc. | Humanized antibodies to gamma-interferon |
| GB0100624D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VII |
| US7767685B2 (en) | 2006-06-29 | 2010-08-03 | King Pharmaceuticals Research And Development, Inc. | Adenosine A2B receptor antagonists |
| GB0906579D0 (en) * | 2009-04-16 | 2009-05-20 | Vernalis R&D Ltd | Pharmaceuticals, compositions and methods of making and using the same |
| CA2991628C (en) | 2015-07-16 | 2020-04-07 | Bioxcel Therapeutics, Inc. | A novel approach for treatment of cancer using immunomodulation |
| AU2016379425B2 (en) | 2015-12-24 | 2021-11-11 | Corvus Pharmaceuticals, Inc. | Methods of treating cancer |
| WO2018187484A1 (en) | 2017-04-04 | 2018-10-11 | Corvus Pharmaceuticals, Inc. | Methods of treating cancer |
| CA3080976A1 (en) * | 2017-11-06 | 2019-05-09 | Corvus Pharmaceuticals, Inc. | Adenosine pathway inhibitors for cancer treatment |
| CN111615389A (zh) * | 2018-02-01 | 2020-09-01 | 科尔沃斯制药股份有限公司 | 药物调配物 |
-
2016
- 2016-12-22 AU AU2016379425A patent/AU2016379425B2/en active Active
- 2016-12-22 ES ES16880133T patent/ES3017686T3/es active Active
- 2016-12-22 CN CN201680082482.7A patent/CN108883107A/zh active Pending
- 2016-12-22 EP EP16880133.0A patent/EP3393475B1/en active Active
- 2016-12-22 KR KR1020187021355A patent/KR20180103918A/ko not_active Ceased
- 2016-12-22 WO PCT/US2016/068459 patent/WO2017112917A1/en not_active Ceased
- 2016-12-22 EA EA201891509A patent/EA201891509A1/ru unknown
- 2016-12-22 US US16/065,012 patent/US10912776B2/en active Active
- 2016-12-22 CA CA3009527A patent/CA3009527C/en active Active
- 2016-12-22 MX MX2018007765A patent/MX391382B/es unknown
- 2016-12-22 JP JP2018533135A patent/JP6847958B2/ja active Active
-
2018
- 2018-06-21 IL IL260199A patent/IL260199B/en unknown
- 2018-06-22 ZA ZA2018/04227A patent/ZA201804227B/en unknown
-
2020
- 2020-12-17 US US17/125,596 patent/US12023337B2/en active Active
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