|
US20040049014A1
(en)
*
|
1988-12-28 |
2004-03-11 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE69322289T2
(de)
*
|
1992-12-29 |
1999-05-20 |
Genentech, Inc., South San Francisco, Calif. |
Behandlung von entzündlichen darmerkrankungen mit interferon-gamma-inhibitoren
|
|
US20030059428A1
(en)
*
|
1993-02-26 |
2003-03-27 |
Boris Skurkovich |
Treatment of autoimmune diseases
|
|
US20030086925A1
(en)
*
|
1996-12-23 |
2003-05-08 |
Advanced Biotherapy, Inc. |
Treatment of autoimmune diseases
|
|
US20030228310A1
(en)
*
|
1996-12-23 |
2003-12-11 |
Advanced Biotherapy, Inc. |
Treatment of skin diseases
|
|
US20030223995A1
(en)
*
|
1996-12-23 |
2003-12-04 |
Advanced Biotherapy, Inc. |
Treatment of pemphigus vulgaris
|
|
WO1999027964A1
(en)
*
|
1997-12-01 |
1999-06-10 |
Cfy Biomedicals, Inc. |
Multivalent recombinant antibodies for treating hrv infections
|
|
US20030035798A1
(en)
*
|
2000-08-16 |
2003-02-20 |
Fang Fang |
Humanized antibodies
|
|
CA2352572C
(en)
*
|
1998-12-01 |
2010-04-20 |
Abbvie Biotherapeutics Inc. |
Humanized antibodies to gamma-interferon
|
|
EP1137766B1
(de)
*
|
1998-12-09 |
2005-09-28 |
Protein Design Labs, Inc. |
Verwendung von il-12 antikörpern zur behandlung von psoriasis
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US7087726B2
(en)
*
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
CA2454358A1
(en)
|
2001-07-19 |
2003-07-31 |
Perlan Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
|
US7084257B2
(en)
|
2001-10-05 |
2006-08-01 |
Amgen Inc. |
Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
|
|
EP2305312B1
(de)
|
2001-10-10 |
2015-03-04 |
ratiopharm GmbH |
Neumodulierung und Glykokonjugation von Follitropin (FSH)
|
|
US7244592B2
(en)
*
|
2002-03-07 |
2007-07-17 |
Dyax Corp. |
Ligand screening and discovery
|
|
AU2003220219A1
(en)
|
2002-03-15 |
2003-09-29 |
Schering Corporation |
Methods of modulating cd200 receptors
|
|
CA2486147A1
(en)
|
2002-05-17 |
2003-11-27 |
Protein Design Labs, Inc. |
Treatment of crohn's disease or psoriasis using anti-inteferon gamma antibodies
|
|
US20050019323A1
(en)
*
|
2002-05-22 |
2005-01-27 |
Protein Design Labs, Inc. |
Treatment of Crohn's disease or psoriasis using anti-interferon gamma antibodies
|
|
US20040052791A1
(en)
*
|
2002-05-22 |
2004-03-18 |
Rolf Ehrhardt |
Treatment of Crohn's disease or psoriasis using anti-interferon gamma antibodies
|
|
US20040052790A1
(en)
*
|
2002-09-18 |
2004-03-18 |
Advanced Biotherapy, Inc. |
Treatment of schizophrenia
|
|
US7217797B2
(en)
*
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7365168B2
(en)
*
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7217798B2
(en)
*
|
2003-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of Fc-fusion protein serum half-lives by mutagenesis
|
|
US7335743B2
(en)
*
|
2002-10-16 |
2008-02-26 |
Amgen Inc. |
Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
|
|
EP1560595A4
(de)
*
|
2002-10-17 |
2005-12-28 |
Amgen Inc |
Humanes gamma-interferon neutralisierende fab-fragmente aus vollhumanem antikörper
|
|
WO2004041862A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
EP1572106B1
(de)
|
2002-11-15 |
2010-05-05 |
Novartis Vaccines and Diagnostics, Inc. |
Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust
|
|
JP4902961B2
(ja)
|
2002-12-23 |
2012-03-21 |
シェーリング コーポレイション |
哺乳動物サイトカインの用途;関連試薬
|
|
SI1601694T1
(sl)
|
2003-03-10 |
2010-01-29 |
Schering Corp |
Uporabe IL-23 antagonistov; sorodni reagenti
|
|
JP4685764B2
(ja)
*
|
2003-04-10 |
2011-05-18 |
アボット バイオセラピューティクス コーポレイション |
変異誘発による抗体のFcRn結合親和力又は血清半減期の改変
|
|
NZ549040A
(en)
|
2004-02-17 |
2009-07-31 |
Schering Corp |
Use for interleukin-33 (IL33) and the IL-33 receptor complex
|
|
HRP20130782T1
(en)
|
2004-04-02 |
2013-09-30 |
The Regents Of The University Of California, Office Of Technology Transfer |
Methods and compositions for treating and preventing disease associated with alpha v beta 5 integrin
|
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
|
US20050276806A1
(en)
*
|
2004-06-15 |
2005-12-15 |
Advanced Biotherapy, Inc. |
Treatment of autism
|
|
EP2292758A3
(de)
|
2004-12-20 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
Verwendung von Säuger-Zytokin; verwandte Reagenzien
|
|
CA2589860A1
(en)
*
|
2005-01-24 |
2006-08-03 |
Amgen Inc. |
Humanized anti-amyloid antibody
|
|
EA013118B1
(ru)
|
2005-01-27 |
2010-02-26 |
Новиммун С.А. |
Антитела против интерферона-гамма и способы их применения
|
|
TWI671403B
(zh)
*
|
2005-03-31 |
2019-09-11 |
中外製藥股份有限公司 |
控制組裝之多肽的製造方法
|
|
EP2277916A3
(de)
*
|
2005-07-28 |
2011-04-27 |
Novartis AG |
Verwendung von Antikörper zu M-CSF
|
|
JP5457671B2
(ja)
*
|
2005-07-28 |
2014-04-02 |
ノバルティス アーゲー |
M−csf特異的モノクローナル抗体およびその使用
|
|
EP2322219A3
(de)
|
2005-09-01 |
2013-06-05 |
Merck Sharp & Dohme Corp. |
Verwendung von IL-23- und IL-17-Antagonisten zur Behandlung von Augenentzündungsautoimmunerkrankungen
|
|
US20090155850A1
(en)
*
|
2005-10-28 |
2009-06-18 |
The Florida International University Board Of Trustees |
Horse:Human Chimeric Antibodies
|
|
WO2007114325A1
(ja)
|
2006-03-31 |
2007-10-11 |
Chugai Seiyaku Kabushiki Kaisha |
二重特異性抗体を精製するための抗体改変方法
|
|
IN2014DN10515A
(de)
*
|
2006-03-31 |
2015-08-21 |
Chugai Pharmaceutical Co Ltd |
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
|
EP2057193B1
(de)
|
2006-08-04 |
2013-12-18 |
Novartis AG |
Ephb3-spezifischer antikörper und verwendungen davon
|
|
HRP20140081T1
(hr)
*
|
2006-08-18 |
2014-03-28 |
Novartis Ag |
Prlr-specifiäśna antitijela i njihova uporaba
|
|
CN101687031B
(zh)
*
|
2006-10-27 |
2014-05-14 |
勒帕斯公司 |
用于治疗眼疾和眼病的组合物及方法
|
|
KR101581279B1
(ko)
|
2006-10-27 |
2015-12-31 |
엘파스, 인크. |
스핑고신-1-포스페이트 결합을 위한 조성물 및 방법
|
|
CA2672120A1
(en)
|
2006-12-07 |
2008-06-12 |
Novartis Ag |
Antagonistic antibodies against ephb3
|
|
MX2009008104A
(es)
*
|
2007-02-02 |
2009-08-07 |
Amgen Inc |
Hepcidina, antagonistas de hepcidina y metodos de uso.
|
|
CN101668531B
(zh)
|
2007-02-28 |
2014-05-07 |
默沙东公司 |
用于治疗免疫病症的联合治疗
|
|
WO2008150841A1
(en)
|
2007-05-30 |
2008-12-11 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
|
US7709215B2
(en)
|
2007-06-01 |
2010-05-04 |
Cytonics Corporation |
Method for diagnosing and treating acute joint injury
|
|
DK2158315T3
(en)
|
2007-06-25 |
2016-06-06 |
Esbatech Alcon Biomed Res Unit |
Methods of modifying antibodies and modified antibodies with improved functional properties
|
|
DK3059246T3
(en)
*
|
2007-09-26 |
2018-10-01 |
Chugai Pharmaceutical Co Ltd |
Modified constant region of an antibody
|
|
MX336725B
(es)
|
2007-09-26 |
2016-01-28 |
Chugai Pharmaceutical Co Ltd |
Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr).
|
|
US8361465B2
(en)
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
|
BRPI0821110B8
(pt)
|
2007-12-05 |
2021-05-25 |
Chugai Pharmaceutical Co Ltd |
anticorpo de neutralização de anti-nr10/il31ra, composição farmacêutica compreendendo o referido anticorpo e uso do mesmo
|
|
EP2261254A3
(de)
|
2007-12-21 |
2011-04-13 |
Amgen, Inc |
Antiamyloide Antikörper und deren Verwendungen
|
|
CA2711826C
(en)
|
2008-01-25 |
2018-02-27 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
|
TWI700293B
(zh)
|
2008-04-11 |
2020-08-01 |
日商中外製藥股份有限公司 |
重複結合複數個抗原的抗體
|
|
US9315577B2
(en)
|
2008-05-01 |
2016-04-19 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
|
WO2009143167A2
(en)
|
2008-05-19 |
2009-11-26 |
Advaxis |
Dual delivery system for heterologous antigens
|
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
|
CN102246045B
(zh)
|
2008-10-16 |
2014-04-02 |
希托尼克斯公司 |
用于检测和治疗脊柱和关节疼痛的生物标志物和方法
|
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
|
JP2012511026A
(ja)
*
|
2008-12-05 |
2012-05-17 |
エルパス・インコーポレイテッド |
抗脂抗体結晶構造を用いた抗体設計
|
|
US8401799B2
(en)
*
|
2008-12-05 |
2013-03-19 |
Lpath, Inc. |
Antibody design using anti-lipid antibody crystal structures
|
|
WO2010098863A1
(en)
*
|
2009-02-26 |
2010-09-02 |
Lpath, Inc. |
Humanized platelet activating factor antibody design using anti-lipid antibody templates
|
|
JP5787446B2
(ja)
|
2009-03-19 |
2015-09-30 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
EP2409991B1
(de)
|
2009-03-19 |
2017-05-03 |
Chugai Seiyaku Kabushiki Kaisha |
Variante einer konstanten antikörperregion
|
|
WO2010121093A2
(en)
*
|
2009-04-17 |
2010-10-21 |
Lpath, Inc. |
Humanized antibody compositions and methods for binding lysophosphatidic acid
|
|
CN102459344A
(zh)
|
2009-05-15 |
2012-05-16 |
中外制药株式会社 |
抗axl抗体
|
|
CA2767409C
(en)
|
2009-07-24 |
2018-10-30 |
The Regents Of The University Of California |
Methods and compositions for treating and preventing disease associated with .alpha.v.beta.5 integrin
|
|
EA201270228A1
(ru)
|
2009-07-31 |
2012-09-28 |
Медарекс, Инк. |
Полноценные человеческие антитела к btla
|
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
|
ES2636671T3
(es)
|
2010-01-26 |
2017-10-06 |
National Jewish Health |
Métodos para predicción del riesgo, diagnóstico, pronóstico de trastornos pulmonares
|
|
WO2011106723A2
(en)
*
|
2010-02-26 |
2011-09-01 |
Lpath, Inc. |
Anti-paf antibodies
|
|
EP2543730B1
(de)
|
2010-03-04 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Variante einer konstanten antikörperregion
|
|
CN107412756A
(zh)
|
2010-10-01 |
2017-12-01 |
宾夕法尼亚大学理事会 |
李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途
|
|
JP6013915B2
(ja)
|
2010-11-17 |
2016-10-25 |
中外製薬株式会社 |
血液凝固第viii因子の機能を代替する機能を有する多重特異性抗原結合分子
|
|
KR102568454B1
(ko)
|
2010-11-30 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복해서 결합하는 항원 결합 분자
|
|
EP3604330A1
(de)
|
2011-02-25 |
2020-02-05 |
Chugai Seiyaku Kabushiki Kaisha |
Fcgammariib-spezifischer fc-antikörper
|
|
WO2012125551A1
(en)
|
2011-03-11 |
2012-09-20 |
Advaxis |
Listeria-based adjuvants
|
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
|
TW201817745A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
|
BR112014012607A2
(pt)
|
2011-11-23 |
2017-06-20 |
Amgen Inc |
métodos de tratamento usando um inibidor de interferon gama
|
|
SG10201700392UA
(en)
|
2012-03-12 |
2017-03-30 |
Advaxis Inc |
Suppressor cell function inhibition following listeria vaccine treatment
|
|
ES2817897T3
(es)
|
2012-07-23 |
2021-04-08 |
La Jolla Inst Allergy & Immunology |
PTPRS y proteoglicanos en enfermedad autoinmune
|
|
UA117466C2
(uk)
|
2012-12-13 |
2018-08-10 |
Мерк Шарп Енд Доме Корп. |
СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
US9969804B2
(en)
|
2013-04-01 |
2018-05-15 |
The Regents Of The University Of California |
Methods and compositions for treating and preventing disease associated with alpha-V beta-8 integrin
|
|
JP6586087B2
(ja)
|
2013-08-20 |
2019-10-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
Pd−1アンタゴニストとジナシクリブとの組合せでの癌治療
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
JP6736464B2
(ja)
|
2013-08-29 |
2020-08-05 |
シティ・オブ・ホープCity of Hope |
細胞透過性コンジュゲート及びその使用の方法
|
|
SG10201803449VA
(en)
|
2013-09-27 |
2018-05-30 |
Chugai Pharmaceutical Co Ltd |
Method for producing polypeptide heteromultimer
|
|
EP3084003A4
(de)
|
2013-12-17 |
2017-07-19 |
Merck Sharp & Dohme Corp. |
Ifn-gamma-gensignaturbiomarker der tumorreaktion auf pd-1 antagonisten
|
|
AU2015214404B2
(en)
|
2014-02-04 |
2020-10-01 |
Incyte Corporation |
Combination of a PD-1 antagonist and an IDO1 inhibitor for treating cancer
|
|
WO2015119930A1
(en)
|
2014-02-04 |
2015-08-13 |
Pfizer Inc. |
Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer
|
|
WO2015179236A1
(en)
|
2014-05-21 |
2015-11-26 |
Pfizer Inc. |
Combination of an anti-ccr4 antibody and a 4-1bb agonist for treating cancer
|
|
US10414814B2
(en)
|
2014-07-03 |
2019-09-17 |
City Of Hope |
Tumor-selective CTLA-4 antagonists
|
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
MY198017A
(en)
|
2014-08-19 |
2023-07-26 |
Merck Sharp & Dohme |
Anti-tigit antibodies
|
|
CA2955676A1
(en)
|
2014-08-25 |
2016-03-03 |
Pfizer Inc. |
Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
TWI656133B
(zh)
|
2014-12-19 |
2019-04-11 |
日商中外製藥股份有限公司 |
抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
|
|
KR101838645B1
(ko)
|
2014-12-19 |
2018-03-14 |
추가이 세이야쿠 가부시키가이샤 |
항-c5 항체 및 그의 사용 방법
|
|
WO2016115275A1
(en)
|
2015-01-13 |
2016-07-21 |
City Of Hope |
Ctla4-binding protein peptide-linker masks
|
|
EA201791610A1
(ru)
|
2015-01-16 |
2017-12-29 |
Сити Оф Хоуп |
Проникающие в клетку антитела
|
|
WO2016125495A1
(en)
|
2015-02-05 |
2016-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
|
|
EP3263132B1
(de)
|
2015-02-27 |
2023-12-06 |
Chugai Seiyaku Kabushiki Kaisha |
Zusammensetzung zur behandlung von il-6-assoziierten erkrankungen
|
|
JP6951248B2
(ja)
|
2015-03-04 |
2021-10-20 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がんを治療するための、pd−1アンタゴニスト及びエリブリンの組合せ
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
WO2016161018A1
(en)
|
2015-03-30 |
2016-10-06 |
City Of Hope |
Mechanically interlocking complexes
|
|
JP7082484B2
(ja)
|
2015-04-01 |
2022-06-08 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
|
BR112017023867A2
(pt)
|
2015-05-07 |
2018-07-24 |
Novimmune Sa |
métodos e composições para diagnóstico e tratamento de distúrbios em pacientes com níveis elevados de cxcl9 e outros biomarcadores
|
|
US11091543B2
(en)
|
2015-05-07 |
2021-08-17 |
Swedish Orphan Biovitrum Ag |
Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications
|
|
CA2986030A1
(en)
|
2015-05-15 |
2016-11-24 |
City Of Hope |
Chimeric antigen receptor compositions
|
|
BR112017025562A2
(pt)
|
2015-05-29 |
2018-08-07 |
Merck Sharp & Dohme Corp. |
métodos para tratar câncer em um indivíduo e para tratar um indivíduo humano diagnosticado com câncer
|
|
CN114306627A
(zh)
|
2015-08-06 |
2022-04-12 |
希望之城 |
细胞穿透蛋白-抗体缀合物及其使用方法
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
CA2997179A1
(en)
|
2015-09-02 |
2017-03-09 |
The Regents Of The Unversity Of Colorado, A Body Corporate |
Compositions and methods for modulating t-cell mediated immune response
|
|
CN108603037B
(zh)
|
2015-12-10 |
2020-11-17 |
希望之城 |
细胞穿透花青偶联抗体
|
|
WO2017106129A1
(en)
|
2015-12-16 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Anti-lag3 antibodies and antigen-binding fragments
|
|
CA3009527C
(en)
|
2015-12-24 |
2024-01-09 |
Stephen WILLINGHAM |
Methods of treating cancer
|
|
WO2017110981A1
(en)
|
2015-12-25 |
2017-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
|
CA3004288C
(en)
|
2015-12-28 |
2025-05-27 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD FOR PROMOTING THE CLEARANCE EFFICIENCY OF A POLYPEPTIDE CONTAINING THE FC REGION
|
|
BR112018014810A2
(pt)
|
2016-01-22 |
2018-12-11 |
Merck Sharp & Dohme Corp. |
anticorpos anti-fator xi de coagulação
|
|
JP6783312B2
(ja)
|
2016-01-25 |
2020-11-11 |
ファイザー・インク |
がんを処置するためのox40アゴニストおよび4−1bbアゴニストモノクローナル抗体の組み合わせ
|
|
TW202214700A
(zh)
|
2016-03-14 |
2022-04-16 |
日商中外製藥股份有限公司 |
用於癌之治療的細胞傷害誘導治療劑
|
|
CA3019588A1
(en)
|
2016-04-20 |
2017-10-26 |
Merck Sharp & Dohme Corp. |
Cmv neutralizing antigen binding proteins
|
|
AU2017255077B2
(en)
|
2016-04-28 |
2024-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody-containing preparation
|
|
CN116425879A
(zh)
|
2016-06-14 |
2023-07-14 |
默沙东有限责任公司 |
抗-凝血因子xi抗体
|
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
CN109689099B
(zh)
|
2016-08-05 |
2023-02-28 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
|
JOP20190055A1
(ar)
|
2016-09-26 |
2019-03-24 |
Merck Sharp & Dohme |
أجسام مضادة ضد cd27
|
|
JP2019530706A
(ja)
|
2016-10-14 |
2019-10-24 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
尿路上皮がんを治療するための、pd−1アンタゴニスト及びエリブリンの組合せ
|
|
AU2017352033A1
(en)
*
|
2016-10-24 |
2019-06-06 |
Swedish Orphan Biovitrum Ag |
Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications
|
|
ES2908239T3
(es)
|
2016-10-28 |
2022-04-28 |
Astute Medical Inc |
Uso de anticuerpos contra timp-2 para la mejora de la función renal
|
|
US11008325B2
(en)
|
2016-11-14 |
2021-05-18 |
Virginia Commonwealth University |
Inhibitors of cancer invasion, attachment, and/or metastasis
|
|
MX2019012233A
(es)
|
2017-04-13 |
2020-01-14 |
Aduro Biotech Holdings Europe Bv |
Anticuerpos anti-sirpa.
|
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
|
AU2018263868A1
(en)
|
2017-05-02 |
2019-12-12 |
Merck Sharp & Dohme Llc |
Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
|
|
EP3620531A4
(de)
|
2017-05-02 |
2021-03-17 |
National Center of Neurology and Psychiatry |
Verfahren zur vorhersage und beurteilung der therapeutischen wirkung bei erkrankungen im zusammenhang mit il-6 und neutrophilen
|
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
|
JP6889328B2
(ja)
|
2017-07-31 |
2021-06-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
三次元構造に基づくヒト化方法
|
|
WO2019067015A1
(en)
|
2017-09-29 |
2019-04-04 |
City Of Hope |
RECEPTORS OF CHIMERIC ANTIGENS AND BISPECIFIC ANTIBODIES FOR THE TREATMENT OF COAT CELL LYMPHOMA
|
|
BR112020008393A2
(pt)
|
2017-11-01 |
2020-11-03 |
Chugai Seiyaku Kabushiki Kaisha |
variante e isoforma de anticorpos com atividade biológica reduzida
|
|
MA50900A
(fr)
|
2017-11-17 |
2020-09-23 |
Merck Sharp & Dohme |
Anticorps spécifiques du transcrit 3 de type immunoglobuline (ilt3) et leurs utilisations
|
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
|
SG11202007590TA
(en)
|
2018-02-13 |
2020-09-29 |
Merck Sharp & Dohme |
Methods for treating cancer with anti-pd-1 antibodies
|
|
CN112334485B
(zh)
|
2018-04-06 |
2024-09-27 |
百进生物科技公司 |
抗-四次穿膜蛋白33药剂及其组合物以及制备和使用方法
|
|
PT3773713T
(pt)
|
2018-04-06 |
2025-07-29 |
Regeneron Pharma |
Anticorpo agonista do recetor de leptina para usar no aumento da massa óssea num sujeito que sofre de disfunção metabólica ou de hipoleptinemia
|
|
AU2019295855A1
(en)
|
2018-06-29 |
2021-01-28 |
City Of Hope |
CD6 targeted chimeric antigen receptors for treatent of certain autoimmune disorders
|
|
WO2020037215A1
(en)
|
2018-08-17 |
2020-02-20 |
Icahn School Of Medicine At Mount Sinai |
Recombinant newcastle disease viruses and uses thereof for the prevention of rsv disease or human metapneumovirus disease
|
|
US20210221864A1
(en)
|
2018-08-24 |
2021-07-22 |
City Of Hope |
Masked cytokine conjugates
|
|
CA3111066A1
(en)
|
2018-09-13 |
2020-03-19 |
Merck Sharp & Dohme Corp. |
Combination therapy of a pd-1 antagonist and lag3 antagonist for treating patients with non-microsatellite instability-high or proficient mismatch repair colorectal cancer
|
|
JP2022501388A
(ja)
|
2018-09-19 |
2022-01-06 |
ラホヤ インスティチュート フォー イミュノロジー |
関節リウマチにおけるptprs及びプロテオグリカン
|
|
EP3856343A1
(de)
|
2018-09-25 |
2021-08-04 |
Biolegend, Inc. |
Anti-tlr9-mittel und zusammensetzungen sowie verfahren zu ihrer herstellung und verwendung
|
|
JP7467438B2
(ja)
|
2018-10-18 |
2024-04-15 |
メルク・シャープ・アンド・ドーム・エルエルシー |
抗rsv抗体の製剤及びその使用方法
|
|
CN113015748B
(zh)
|
2018-10-31 |
2025-12-12 |
默沙东有限责任公司 |
抗人pd-1抗体晶体及其使用方法
|
|
CN113316458B
(zh)
|
2018-11-07 |
2024-08-02 |
默沙东有限责任公司 |
抗lag3抗体和抗pd-1抗体的共制剂
|
|
EP3898672A1
(de)
|
2018-12-18 |
2021-10-27 |
Regeneron Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur erhöhung des körpergewichts und der magermuskelmasse unter verwendung von antagonisten gegen leptinrezeptor, gdf8 und activin a
|
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
|
EP3969040A1
(de)
|
2019-05-13 |
2022-03-23 |
Regeneron Pharmaceuticals, Inc. |
Kombination von pd-1-inhibitoren und lag-3-inhibitoren zur erhöhung der wirksamkeit bei der behandlung von krebs
|
|
EP3976043A1
(de)
|
2019-05-24 |
2022-04-06 |
Pfizer Inc. |
Kombinationstherapien mit cdk-hemmern
|
|
CN113874036A
(zh)
|
2019-05-24 |
2021-12-31 |
辉瑞公司 |
使用cdk抑制剂的联合治疗
|
|
CN113966343A
(zh)
|
2019-06-11 |
2022-01-21 |
瑞泽恩制药公司 |
结合PcrV的抗PcrV抗体、包含抗PcrV抗体的组合物及其使用方法
|
|
US20220409724A1
(en)
|
2019-10-29 |
2022-12-29 |
Eisai R&D Management Co., Ltd. |
Combination of a pd-1 antagonist, a vegfr/fgfr/ret tyrosine kinase inhibitor and a cbp/beta-catenin inhibitor for treating cancer
|
|
WO2021138454A1
(en)
|
2019-12-30 |
2021-07-08 |
City Of Hope |
Methods of making and using regulatory t cells and effector t cells having chimeric antigen receptors targeted to cd6, cd19, and/or an il-13r for treatment of autoimmune disorders and cancers
|
|
CN115427447B
(zh)
|
2020-01-17 |
2025-02-18 |
百进生物科技公司 |
抗tlr7药剂和组合物以及制备和使用其的方法
|
|
WO2021181233A2
(en)
|
2020-03-09 |
2021-09-16 |
Pfizer Inc. |
Fusion proteins and uses thereof
|
|
CN115698062A
(zh)
*
|
2020-04-06 |
2023-02-03 |
细胞编辑有限责任公司 |
表达嵌合抗原受体并具有降低的促炎细胞因子信号传导的经基因修饰的免疫细胞
|
|
IL297806A
(en)
|
2020-04-30 |
2022-12-01 |
Sairopa B V |
Anti-cd103 antibodies
|
|
KR20230008197A
(ko)
|
2020-05-13 |
2023-01-13 |
화이자 인코포레이티드 |
암을 치료하기 위한 방법, 요법 및 용도
|
|
US20230265175A1
(en)
|
2020-06-25 |
2023-08-24 |
Merck Sharp & Dohme Llc |
High affinity antibodies targeting tau phosphorylated at serine 413
|
|
US20230250173A1
(en)
|
2020-07-01 |
2023-08-10 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
|
WO2022035998A1
(en)
|
2020-08-11 |
2022-02-17 |
City Of Hope |
Compositions and uses of sars-cov-2 targeted chimeric antigen receptor modified nk cells
|
|
WO2022049526A1
(en)
|
2020-09-02 |
2022-03-10 |
Pharmabcine Inc. |
Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer
|
|
IL300884A
(en)
|
2020-09-14 |
2023-04-01 |
Pfizer |
Treatment methods and uses for cancer treatment
|
|
MX2023003414A
(es)
|
2020-09-24 |
2023-04-14 |
Merck Sharp & Dohme Llc |
Formulaciones estables de anticuerpos programados del receptor de muerte 1 (pd-1) y variantes de hialuronidasa y fragmentos de las mismas y metodos de uso de las mismas.
|
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
|
EP4284834A1
(de)
|
2021-01-29 |
2023-12-06 |
Merck Sharp & Dohme LLC |
Zusammensetzungen von antikörpern des rezeptors 1 für programmierten tod und verfahren zur herstellung der zusammensetzungen daraus
|
|
CN112794903B
(zh)
*
|
2021-04-14 |
2021-06-25 |
广州市雷德生物科技有限公司 |
一种特异性结合IFN-γ的抗体及其应用
|
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
JP2025511000A
(ja)
|
2022-03-28 |
2025-04-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
インターフェロンガンマバリアントおよびこれを含む抗原結合分子
|
|
CN119301155A
(zh)
|
2022-07-19 |
2025-01-10 |
百进生物科技公司 |
抗cd157抗体、其抗原结合片段和组合物及其制备和使用方法
|
|
US20260042848A1
(en)
|
2022-08-18 |
2026-02-12 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|
|
KR20250155054A
(ko)
|
2023-03-13 |
2025-10-29 |
리제너론 파마슈티칼스 인코포레이티드 |
흑색종 치료에서의 효능 강화를 위한 pd-1 억제제와 lag-3 억제제의 병용
|
|
WO2024243217A1
(en)
|
2023-05-25 |
2024-11-28 |
BioLegend, Inc. |
Ceacam6 binding antibodies and antigen-binding fragments thereof
|
|
TW202502382A
(zh)
|
2023-06-30 |
2025-01-16 |
美商默沙東有限責任公司 |
治療組合及其用途和治療方法
|
|
TW202502813A
(zh)
|
2023-06-30 |
2025-01-16 |
美商默沙東有限責任公司 |
包含偶聯物的藥物組合的治療方法和用途
|
|
WO2025072313A1
(en)
|
2023-09-27 |
2025-04-03 |
BioLegend, Inc. |
Anti-gpc4 antibodies
|
|
WO2025106736A2
(en)
|
2023-11-15 |
2025-05-22 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating lung cancer
|
|
WO2025226695A1
(en)
|
2024-04-23 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
CN118243913B
(zh)
*
|
2024-05-29 |
2024-08-23 |
上海秤信生物科技有限公司 |
一种质控品保存液及其应用
|
|
WO2026027944A1
(en)
|
2024-07-30 |
2026-02-05 |
Sairopa B.V. |
Anti-sirp alpha antibody formulations and uses thereof
|