DE602006009834D1 - Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankung - Google Patents
Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankungInfo
- Publication number
- DE602006009834D1 DE602006009834D1 DE602006009834T DE602006009834T DE602006009834D1 DE 602006009834 D1 DE602006009834 D1 DE 602006009834D1 DE 602006009834 T DE602006009834 T DE 602006009834T DE 602006009834 T DE602006009834 T DE 602006009834T DE 602006009834 D1 DE602006009834 D1 DE 602006009834D1
- Authority
- DE
- Germany
- Prior art keywords
- inflammable
- autoimmune
- antagonists
- treatment
- eye disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71379205P | 2005-09-01 | 2005-09-01 | |
US83731206P | 2006-08-11 | 2006-08-11 | |
PCT/US2006/033840 WO2007027761A2 (en) | 2005-09-01 | 2006-08-30 | Use of il-23 and il-17 antagonists to treat autoimmune ocular inflammatory disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006009834D1 true DE602006009834D1 (de) | 2009-11-26 |
Family
ID=37686002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006009834T Active DE602006009834D1 (de) | 2005-09-01 | 2006-08-30 | Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankung |
Country Status (22)
Country | Link |
---|---|
US (6) | US20080199460A1 (de) |
EP (3) | EP2116258A1 (de) |
JP (3) | JP2009507023A (de) |
CN (1) | CN101296706B (de) |
AT (1) | ATE445415T1 (de) |
AU (1) | AU2006284841B2 (de) |
BR (1) | BRPI0615297A2 (de) |
CA (1) | CA2621086A1 (de) |
CY (1) | CY1110606T1 (de) |
DE (1) | DE602006009834D1 (de) |
DK (1) | DK1933869T3 (de) |
ES (1) | ES2333260T3 (de) |
HK (1) | HK1119578A1 (de) |
HR (1) | HRP20100014T1 (de) |
NO (1) | NO20081574L (de) |
NZ (2) | NZ595262A (de) |
PL (1) | PL1933869T3 (de) |
PT (1) | PT1933869E (de) |
RS (1) | RS51142B (de) |
SI (1) | SI1933869T1 (de) |
TW (2) | TWI463993B (de) |
WO (1) | WO2007027761A2 (de) |
Families Citing this family (64)
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GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
KR101453570B1 (ko) * | 2005-12-02 | 2014-10-22 | 제넨테크, 인크. | Il-22 및 il-22r에 결합하는 항체를 포함하는,사이토카인 신호 전달과 관련된 질환 및 장애 치료용조성물 및 치료 방법 |
US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
EP2044118A2 (de) | 2006-06-13 | 2009-04-08 | Zymogenetics, Inc. | Il-17- und il-23-antagonisten sowie verwendungsverfahren |
US7767206B2 (en) | 2006-10-02 | 2010-08-03 | Amgen Inc. | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto |
NZ597915A (en) * | 2007-02-28 | 2013-08-30 | Merck Sharp & Dohme | Combination therapy for treatment of immune disorders |
EP2150564A2 (de) * | 2007-04-27 | 2010-02-10 | ZymoGenetics, Inc. | Il-17a-, il-17f- und il-23p19-antagonisten und verwendungsverfahren |
WO2009014263A1 (ja) * | 2007-07-26 | 2009-01-29 | Osaka University | インターロイキン6受容体阻害剤を有効成分とする眼炎症疾患治療剤 |
WO2009023267A2 (en) * | 2007-08-15 | 2009-02-19 | President And Fellows Of Harvard College | Methods for modulating development and expansion of il-17 expressing cells |
MX2010005783A (es) | 2007-11-27 | 2010-08-10 | Ablynx Nv | Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas. |
WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
CA2711696C (en) * | 2008-01-09 | 2021-10-26 | Reza Dana | Therapeutic compositions for treatment of ocular inflammatory disorders |
BRPI0907196B1 (pt) * | 2008-02-21 | 2021-05-25 | Kirin-Amgen Inc | Uso de um antagonista de il-17ra-il-17rb |
KR101508086B1 (ko) | 2008-05-05 | 2015-04-07 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
JP2012515164A (ja) * | 2009-01-09 | 2012-07-05 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 角膜障害を処置するための治療組成物 |
US20120014970A1 (en) * | 2009-01-09 | 2012-01-19 | Reza Dana | Therapeutic Compositions for Treatment of Corneal Disorders |
NZ595005A (en) * | 2009-04-01 | 2014-04-30 | Genentech Inc | Treatment of insulin-resistant disorders |
PE20160652A1 (es) | 2009-05-05 | 2016-07-09 | Novimmune Sa | Anticuerpos que se unen a il-17f |
US9301997B2 (en) | 2009-09-21 | 2016-04-05 | Peptinov Sas | Method of vaccination for limiting articular inflammation in rheumatoid arthritis and multiple sclerosis by administering IL-23 peptides |
UA112288C2 (uk) | 2010-01-15 | 2016-08-25 | Кірін-Емджен, Інк. | Склад антитіла, що специфічно зв'язує рецептор а іl-17, і терапевтичні режими |
US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
CN103221422B (zh) | 2010-07-29 | 2017-03-29 | 十一生物治疗股份有限公司 | 嵌合il‑1受体i型激动剂和拮抗剂 |
CN103154031A (zh) * | 2010-10-08 | 2013-06-12 | 诺华有限公司 | 利用il-17拮抗剂治疗牛皮癣的方法 |
JP6126532B2 (ja) | 2010-11-04 | 2017-05-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗il−23抗体 |
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WO2013059644A1 (en) * | 2011-10-21 | 2013-04-25 | Baylor College Of Medicine | Method to measure inflammation in the conjunctiva of patients with tear dysfunction |
WO2013116682A1 (en) | 2012-02-02 | 2013-08-08 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating il-17 |
AU2013244999A1 (en) | 2012-04-05 | 2014-09-25 | F. Hoffmann-La Roche Ag | Bispecific antibodies against human TWEAK and human IL17 and uses thereof |
EP3326649B1 (de) | 2012-05-03 | 2022-02-09 | Boehringer Ingelheim International GmbH | Anti-il-23p19-antikörper |
ES2711554T3 (es) | 2012-05-22 | 2019-05-06 | Bristol Myers Squibb Co | Anticuerpos biespecíficos contra IL-17A/F IL-23 y sus usos |
WO2014093206A1 (en) * | 2012-12-13 | 2014-06-19 | Merck Sharp & Dohme Corp. | Lyophilized spherical pellets of anti-il-23 antibodies |
WO2014107737A2 (en) * | 2013-01-07 | 2014-07-10 | Eleven Biotherapeutics, Inc. | Local delivery of il-17 inhibitors for treating ocular disease |
ES2884813T3 (es) | 2013-03-13 | 2021-12-13 | Buzzard Pharmaceuticals AB | Formulaciones de citoquina quimérica para administración ocular |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
US9603882B2 (en) | 2013-08-13 | 2017-03-28 | Industrial Technology Research Institute | Method for modulating Th17 cells and method for treating a disease related to modulation of Th17 cells |
EP3172339A1 (de) | 2014-07-24 | 2017-05-31 | Boehringer Ingelheim International GmbH | Biomarker zur verwendung bei der behandlung von erkrankungen im zusammenhang mit il-23a |
KR102523914B1 (ko) | 2014-09-03 | 2023-04-19 | 베링거잉겔하임인터내쇼날유한회사 | Il-23a 및 tnf-알파를 표적으로 하는 화합물 및 이의 용도 |
AR102417A1 (es) * | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
PE20171138A1 (es) | 2014-12-23 | 2017-08-09 | 4D Pharma Res Ltd | Modulacion inmunitaria |
EP3400953A1 (de) | 2014-12-23 | 2018-11-14 | 4D Pharma Research Limited | Pirinpolypeptid und immunmodulation |
EP3242714B1 (de) | 2014-12-31 | 2021-06-02 | Stimwave Technologies Incorporated | Antennenanordnung |
CN107407677B (zh) * | 2015-01-28 | 2020-07-17 | 豪夫迈·罗氏有限公司 | 多发性硬化的基因表达标志和治疗 |
CN104725514A (zh) * | 2015-02-06 | 2015-06-24 | 中国药科大学 | 新型il23拮抗剂 |
ME03563B (de) | 2015-06-15 | 2020-07-20 | 4D Pharma Res Ltd | Zusammensetzungen mit bakterienstämmen |
ES2766867T3 (es) | 2015-06-15 | 2020-06-15 | 4D Pharma Res Ltd | Composiciones que comprenden cepas bacterianas |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
LT3240554T (lt) | 2015-06-15 | 2019-11-11 | 4D Pharma Res Ltd | Blautia stercosis ir wexlerae, skirtos naudoti uždegiminių ir autoimuninių ligų gydymui |
CN116672446A (zh) | 2015-09-17 | 2023-09-01 | 美国安进公司 | 使用il23途径生物标志物预测il23拮抗剂的临床应答 |
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MA41013B1 (fr) | 2015-11-20 | 2018-07-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
NZ745678A (en) | 2016-03-04 | 2019-03-29 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
KR20200019882A (ko) | 2017-05-22 | 2020-02-25 | 4디 파마 리서치 리미티드 | 세균 균주를 포함하는 조성물 |
EP3630942B1 (de) | 2017-05-24 | 2022-11-30 | 4D Pharma Research Limited | Zusammensetzungen mit bakterienstamm |
PT3638271T (pt) | 2017-06-14 | 2021-01-05 | 4D Pharma Res Ltd | Composições contendo estirpes bacterianas |
HUE059249T2 (hu) | 2017-06-14 | 2022-11-28 | 4D Pharma Res Limited | Baktériumtörzseket tartalmazó készítmények |
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-
2006
- 2006-08-30 DE DE602006009834T patent/DE602006009834D1/de active Active
- 2006-08-30 ES ES06813945T patent/ES2333260T3/es active Active
- 2006-08-30 BR BRPI0615297-0A patent/BRPI0615297A2/pt not_active IP Right Cessation
- 2006-08-30 AU AU2006284841A patent/AU2006284841B2/en not_active Ceased
- 2006-08-30 RS RSP-2009/0529A patent/RS51142B/sr unknown
- 2006-08-30 DK DK06813945.0T patent/DK1933869T3/da active
- 2006-08-30 US US11/512,622 patent/US20080199460A1/en not_active Abandoned
- 2006-08-30 NZ NZ595262A patent/NZ595262A/xx not_active IP Right Cessation
- 2006-08-30 SI SI200630517T patent/SI1933869T1/sl unknown
- 2006-08-30 WO PCT/US2006/033840 patent/WO2007027761A2/en active Application Filing
- 2006-08-30 CN CN2006800403078A patent/CN101296706B/zh not_active Expired - Fee Related
- 2006-08-30 EP EP09164605A patent/EP2116258A1/de not_active Withdrawn
- 2006-08-30 PL PL06813945T patent/PL1933869T3/pl unknown
- 2006-08-30 EP EP06813945A patent/EP1933869B1/de not_active Revoked
- 2006-08-30 CA CA002621086A patent/CA2621086A1/en not_active Abandoned
- 2006-08-30 NZ NZ566424A patent/NZ566424A/en not_active IP Right Cessation
- 2006-08-30 AT AT06813945T patent/ATE445415T1/de active
- 2006-08-30 PT PT06813945T patent/PT1933869E/pt unknown
- 2006-08-30 JP JP2008529228A patent/JP2009507023A/ja not_active Withdrawn
- 2006-08-30 EP EP10180648.7A patent/EP2322219A3/de not_active Withdrawn
- 2006-08-31 TW TW101115664A patent/TWI463993B/zh not_active IP Right Cessation
- 2006-08-31 TW TW095132202A patent/TWI372061B/zh not_active IP Right Cessation
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2008
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- 2008-10-24 HK HK08111743.9A patent/HK1119578A1/xx not_active IP Right Cessation
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2009
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- 2009-12-21 US US12/643,166 patent/US20100111954A1/en not_active Abandoned
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2010
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- 2010-01-12 CY CY20101100034T patent/CY1110606T1/el unknown
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2011
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- 2011-06-28 JP JP2011143593A patent/JP5462838B2/ja not_active Expired - Fee Related
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2013
- 2013-08-06 US US13/960,441 patent/US20130323251A1/en not_active Abandoned
- 2013-08-13 JP JP2013168006A patent/JP2014005285A/ja active Pending
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2014
- 2014-05-12 US US14/274,905 patent/US20140248279A1/en not_active Abandoned
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