ATE515288T1 - Carboxy-amido-triazole zur lokalisierten behandlung von augenerkrankungen - Google Patents
Carboxy-amido-triazole zur lokalisierten behandlung von augenerkrankungenInfo
- Publication number
- ATE515288T1 ATE515288T1 AT05800193T AT05800193T ATE515288T1 AT E515288 T1 ATE515288 T1 AT E515288T1 AT 05800193 T AT05800193 T AT 05800193T AT 05800193 T AT05800193 T AT 05800193T AT E515288 T1 ATE515288 T1 AT E515288T1
- Authority
- AT
- Austria
- Prior art keywords
- cai
- localized treatment
- triazoles
- amido
- carboxy
- Prior art date
Links
- 208000030533 eye disease Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000002411 adverse Effects 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61268304P | 2004-09-24 | 2004-09-24 | |
| PCT/US2005/035067 WO2006037106A2 (en) | 2004-09-24 | 2005-09-26 | Carboxy-amido-triazoles for the localized treatment of ocular diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE515288T1 true ATE515288T1 (de) | 2011-07-15 |
Family
ID=35462243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05800193T ATE515288T1 (de) | 2004-09-24 | 2005-09-26 | Carboxy-amido-triazole zur lokalisierten behandlung von augenerkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20060116404A1 (de) |
| EP (1) | EP1802373B1 (de) |
| JP (1) | JP2008514645A (de) |
| AT (1) | ATE515288T1 (de) |
| AU (1) | AU2005289415A1 (de) |
| CA (1) | CA2581126A1 (de) |
| ES (1) | ES2369554T3 (de) |
| NZ (1) | NZ554686A (de) |
| WO (1) | WO2006037106A2 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160106717A1 (en) | 2004-09-24 | 2016-04-21 | Gen Pharma Holdings LLC | Cai-based systems and methods for the localized treatment of uveitis |
| US20060116404A1 (en) * | 2004-09-24 | 2006-06-01 | Gary Robinson | CAI-based systems and methods for the localized treatment of ocular and other diseases |
| NZ565954A (en) * | 2005-07-27 | 2012-03-30 | Univ Florida | Use of heat shock inducing compound and an agent that increases stem cell mobilization int he manufacture of a medicament to treat ocular disease |
| WO2007136404A2 (en) * | 2005-11-03 | 2007-11-29 | Clemson University | Lysophospholipids solubilized single-walled carbon nanotubes |
| CN101164538B (zh) * | 2006-10-16 | 2011-12-14 | 中国医学科学院基础医学研究所 | 羧胺三唑类化合物及其盐在制备治疗疼痛性疾病和/或炎症性疾病的药物中的应用 |
| US7750018B2 (en) | 2006-12-06 | 2010-07-06 | Tactical Therapeutics, Inc | Use of carboxiamidotriazole (CAI) orotate in macular degeneration |
| US9445975B2 (en) * | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| US9364433B2 (en) | 2011-04-28 | 2016-06-14 | Borje S. Andersson | Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same |
| ES2666857T3 (es) | 2011-07-18 | 2018-05-08 | Mor-Research Applications Ltd. | Un dispositivo para ajustar la presión intraocular |
| EP2877195B1 (de) * | 2012-07-27 | 2018-03-21 | Curonz Holdings Company Limited | Verfahren zur behandlung von sehnervenschäden, ophthalmischer ischämie oder ophthalmischen reperfusionsschäden |
| US10342699B2 (en) | 2012-08-03 | 2019-07-09 | J.D. Franco & Co., Llc | Systems and methods for treating eye diseases |
| US20140303254A1 (en) * | 2013-04-08 | 2014-10-09 | InnoPharma Licensing LLC | Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation |
| AU2014302458A1 (en) * | 2013-06-26 | 2015-12-24 | Proteostasis Therapeutics, Inc. | Methods of modulating CFTR activity |
| US9630909B2 (en) | 2013-06-27 | 2017-04-25 | Mylan Laboratories Ltd | Process for the preparation of nepafenac |
| PL3016654T3 (pl) * | 2013-07-01 | 2019-02-28 | Bruschettini S.R.L. | Kwas tauroursodeoksycholowy (TUDCA) do zastosowania w leczeniu zaburzeń neurodegeneracyjnych |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016061378A1 (en) * | 2014-10-16 | 2016-04-21 | Gen Pharma Holdings, Llc | Cai-based systems and methods for the localized treatment of uveitis |
| WO2016109586A1 (en) * | 2014-12-29 | 2016-07-07 | Ocudyne, Llc | Apparatus and method for treating eye diseases |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| AU2017229852B2 (en) | 2016-03-09 | 2022-03-03 | J.D. Franco & Co., Llc | Systems and methods for treating eye diseases using retrograde blood flow |
| US11690985B2 (en) | 2016-09-24 | 2023-07-04 | J.D. Franco & Co., Llc | Systems and methods for single puncture percutaneous reverse blood flow |
| CA3046006A1 (en) | 2016-12-08 | 2018-06-14 | Michael Calhoun | Methods and devices for treating an eye using a filter |
| CN106680412B (zh) * | 2016-12-14 | 2018-11-06 | 南京济群医药科技股份有限公司 | 一种奈帕芬胺有关物质的rt-hplc检测方法 |
| WO2018140371A1 (en) | 2017-01-25 | 2018-08-02 | Rmvidlund Llc | Blood vessel access and closure devices and related methods of use |
| US10898212B2 (en) | 2017-05-07 | 2021-01-26 | J.D. Franco & Co., Llc | Devices and methods for treating an artery |
| US10779929B2 (en) | 2017-10-06 | 2020-09-22 | J.D. Franco & Co., Llc | Treating eye diseases by deploying a stent |
| US10398880B2 (en) | 2017-11-02 | 2019-09-03 | J.D. Franco & Co., Llc | Medical systems, devices, and related methods |
| US10758254B2 (en) | 2017-12-15 | 2020-09-01 | J.D. Franco & Co., Llc | Medical systems, devices, and related methods |
| US11478249B2 (en) | 2018-02-23 | 2022-10-25 | J.D. Franco & Co., Llc | Ophthalmic artery therapy under reverse flow |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| CN111249277A (zh) * | 2018-12-03 | 2020-06-09 | 中国医学科学院基础医学研究所 | 羧胺三唑类化合物在制备治疗或预防自身炎症性疾病的药物中的应用 |
| US10765843B2 (en) | 2018-12-31 | 2020-09-08 | J.D. Franco & Co., Llc | Intravascular devices, systems, and methods to address eye disorders |
| CN114786731A (zh) | 2019-10-10 | 2022-07-22 | 科达制药股份有限公司 | 治疗眼部病症的方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4590201A (en) | 1984-02-02 | 1986-05-20 | Merck & Co., Inc. | 5-amino or substituted amino 1,2,3-triazoles |
| US4853224A (en) * | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| US5817075A (en) * | 1989-08-14 | 1998-10-06 | Photogenesis, Inc. | Method for preparation and transplantation of planar implants and surgical instrument therefor |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US5770592A (en) * | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
| US5679666A (en) * | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
| GB9126209D0 (en) * | 1991-12-10 | 1992-02-12 | Orion Yhtymae Oy | Drug formulations for parenteral use |
| US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
| US5602156A (en) * | 1993-09-17 | 1997-02-11 | The United States Of America As Represented By The Department Of Health And Human Services | Method for inhibiting metalloproteinase expression |
| US5744492A (en) * | 1993-09-17 | 1998-04-28 | United States Of America | Method for inhibiting angiogenesis |
| US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US5868728A (en) * | 1995-02-28 | 1999-02-09 | Photogenesis, Inc. | Medical linear actuator for surgical delivery, manipulation, and extraction |
| US5869079A (en) | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5736152A (en) * | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| EP0995435B1 (de) * | 1997-05-14 | 2007-04-25 | Senju Pharmaceutical Co., Ltd. | Wässrige suspensionspräparationen mit exzellenter redispersibilität |
| ATE289801T1 (de) * | 1998-12-22 | 2005-03-15 | Us Health | Verabreichungssystem für wasserunlösliche arzneistoffe |
| US6682758B1 (en) * | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| GB9918180D0 (en) * | 1999-08-02 | 1999-10-06 | Smithkline Beecham Plc | Novel compositions |
| CN1144585C (zh) | 2000-12-13 | 2004-04-07 | 华扩达动物科学[I.P.2]有限公司 | 含有半胱胺或其盐类的促进动物快速生长的组合物及用途 |
| CA2479665C (en) * | 2002-03-20 | 2011-08-30 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
| EP1571225A1 (de) * | 2004-03-02 | 2005-09-07 | PrimaGen Holding B.V. | Diagnose von Krankheiten und Überwachung einer Therapie unter Verwendung des AC133 Gens |
| US7276050B2 (en) * | 2004-03-02 | 2007-10-02 | Alan Franklin | Trans-scleral drug delivery method and apparatus |
| WO2005107470A2 (en) * | 2004-04-29 | 2005-11-17 | University Of Florida Research Foundation, Inc. | Use of carbonic anhydrase inhibitors for insect control and malaria treatment |
| US20060116404A1 (en) * | 2004-09-24 | 2006-06-01 | Gary Robinson | CAI-based systems and methods for the localized treatment of ocular and other diseases |
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- 2005-09-26 ES ES05800193T patent/ES2369554T3/es active Active
- 2005-09-26 JP JP2007533782A patent/JP2008514645A/ja active Pending
- 2005-09-26 AT AT05800193T patent/ATE515288T1/de not_active IP Right Cessation
- 2005-09-26 CA CA002581126A patent/CA2581126A1/en not_active Abandoned
- 2005-09-26 EP EP05800193A patent/EP1802373B1/de not_active Not-in-force
- 2005-09-26 NZ NZ554686A patent/NZ554686A/en not_active IP Right Cessation
- 2005-09-26 WO PCT/US2005/035067 patent/WO2006037106A2/en not_active Ceased
- 2005-09-26 AU AU2005289415A patent/AU2005289415A1/en not_active Abandoned
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2011
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2013
- 2013-11-19 US US14/083,794 patent/US20140079694A1/en not_active Abandoned
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2016
- 2016-09-22 US US15/273,456 patent/US20170007581A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006037106A3 (en) | 2006-12-21 |
| AU2005289415A1 (en) | 2006-04-06 |
| EP1802373A2 (de) | 2007-07-04 |
| JP2008514645A (ja) | 2008-05-08 |
| US20060116404A1 (en) | 2006-06-01 |
| US20140079694A1 (en) | 2014-03-20 |
| WO2006037106A2 (en) | 2006-04-06 |
| EP1802373B1 (de) | 2011-07-06 |
| ES2369554T3 (es) | 2011-12-01 |
| US20140154246A1 (en) | 2014-06-05 |
| US20170007581A1 (en) | 2017-01-12 |
| CA2581126A1 (en) | 2006-04-06 |
| NZ554686A (en) | 2011-06-30 |
| US20110274748A1 (en) | 2011-11-10 |
| US8614235B2 (en) | 2013-12-24 |
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