JP2019501145A5 - - Google Patents
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- Publication number
- JP2019501145A5 JP2019501145A5 JP2018528650A JP2018528650A JP2019501145A5 JP 2019501145 A5 JP2019501145 A5 JP 2019501145A5 JP 2018528650 A JP2018528650 A JP 2018528650A JP 2018528650 A JP2018528650 A JP 2018528650A JP 2019501145 A5 JP2019501145 A5 JP 2019501145A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cancer
- composition according
- checkpoint inhibitor
- fucose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562263228P | 2015-12-04 | 2015-12-04 | |
| US62/263,228 | 2015-12-04 | ||
| US201662308583P | 2016-03-15 | 2016-03-15 | |
| US62/308,583 | 2016-03-15 | ||
| US201662321857P | 2016-04-13 | 2016-04-13 | |
| US62/321,857 | 2016-04-13 | ||
| PCT/US2016/064783 WO2017096274A1 (en) | 2015-12-04 | 2016-12-02 | Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501145A JP2019501145A (ja) | 2019-01-17 |
| JP2019501145A5 true JP2019501145A5 (enExample) | 2020-01-16 |
| JP6906520B2 JP6906520B2 (ja) | 2021-07-21 |
Family
ID=58797961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528650A Active JP6906520B2 (ja) | 2015-12-04 | 2016-12-02 | チェックポイント阻害剤と組みわせて２−デオキシ−２−フルオロ−ｌ−フコースを用いる癌治療 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20180353524A1 (enExample) |
| EP (1) | EP3383404A4 (enExample) |
| JP (1) | JP6906520B2 (enExample) |
| KR (1) | KR20180086233A (enExample) |
| CN (1) | CN108289903B (enExample) |
| AU (1) | AU2016362993A1 (enExample) |
| BR (1) | BR112018011261A2 (enExample) |
| CA (1) | CA3005997A1 (enExample) |
| EA (1) | EA201891340A1 (enExample) |
| IL (1) | IL259479B (enExample) |
| MX (1) | MX385283B (enExample) |
| SG (2) | SG11201804263PA (enExample) |
| WO (1) | WO2017096274A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101950520B1 (ko) | 2010-08-05 | 2019-02-20 | 시애틀 지네틱스, 인크. | 푸코스 유사체를 사용한 생체 내에서의 단백질 푸코실화 억제 방법 |
| TWI773694B (zh) | 2016-10-11 | 2022-08-11 | 美商艾吉納斯公司 | 抗ｌａｇ－３抗體及其使用方法 |
| KR102687149B1 (ko) * | 2017-06-07 | 2024-07-24 | 씨젠 인크. | 감소된 표면 푸코실화를 갖는 t 세포 및 이를 생산하고 사용하는 방법 |
| US11911404B2 (en) * | 2017-10-13 | 2024-02-27 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune surveillance in melanoma |
| AU2019324170A1 (en) | 2018-08-23 | 2021-02-18 | Seagen, Inc. | Anti-TIGIT antibodies |
| CA3123591A1 (en) * | 2018-12-19 | 2020-06-25 | Seagen Inc. | Controlled fucosylation of antibodies |
| WO2021034774A1 (en) * | 2019-08-16 | 2021-02-25 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune modulation in cancer |
| CN111973749B (zh) * | 2020-09-07 | 2023-03-21 | 威海人生药业集团股份有限公司 | 一种抗肿瘤免疫治疗的药物组合物 |
| AU2022238571A1 (en) | 2021-03-18 | 2023-09-14 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| WO2022221766A1 (en) * | 2021-04-16 | 2022-10-20 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune modulation in cancer |
| CN113274502B (zh) * | 2021-05-05 | 2023-01-03 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 用于特定型三阴乳腺癌免疫治疗的组合物 |
| US20240238318A1 (en) * | 2021-05-06 | 2024-07-18 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | L-fucose and anti-androgen receptor therapy for treatment of cancer |
| CN113413465B (zh) * | 2021-06-15 | 2022-06-03 | 北京大学 | 岩藻糖基化抑制剂在抗癌导致炎症中的应用 |
| CN115466297B (zh) * | 2022-08-25 | 2023-07-07 | 青岛农业大学 | L-岩藻糖的应用以及动物饲料 |
| WO2024077106A2 (en) * | 2022-10-04 | 2024-04-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Leveraging l-fucose-mediated signaling to induce monocyte-derived dendritic cell polarization |
| WO2024191807A1 (en) | 2023-03-10 | 2024-09-19 | Seagen Inc. | Methods of treating cancer with anti-tigit antibodies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101950520B1 (ko) | 2010-08-05 | 2019-02-20 | 시애틀 지네틱스, 인크. | 푸코스 유사체를 사용한 생체 내에서의 단백질 푸코실화 억제 방법 |
| JP2016540042A (ja) * | 2013-11-05 | 2016-12-22 | コグネート バイオサービシズ， インコーポレイテッド | がんを処置するためのチェックポイント阻害剤および治療薬の組合せ |
-
2016
- 2016-12-02 CN CN201680071076.0A patent/CN108289903B/zh not_active Expired - Fee Related
- 2016-12-02 JP JP2018528650A patent/JP6906520B2/ja active Active
- 2016-12-02 SG SG11201804263PA patent/SG11201804263PA/en unknown
- 2016-12-02 MX MX2018006674A patent/MX385283B/es unknown
- 2016-12-02 AU AU2016362993A patent/AU2016362993A1/en not_active Abandoned
- 2016-12-02 CA CA3005997A patent/CA3005997A1/en not_active Abandoned
- 2016-12-02 BR BR112018011261A patent/BR112018011261A2/pt not_active Application Discontinuation
- 2016-12-02 US US15/781,256 patent/US20180353524A1/en not_active Abandoned
- 2016-12-02 SG SG10202005298RA patent/SG10202005298RA/en unknown
- 2016-12-02 KR KR1020187017824A patent/KR20180086233A/ko not_active Withdrawn
- 2016-12-02 EP EP16871645.4A patent/EP3383404A4/en not_active Withdrawn
- 2016-12-02 WO PCT/US2016/064783 patent/WO2017096274A1/en not_active Ceased
- 2016-12-02 EA EA201891340A patent/EA201891340A1/ru unknown
-
2018
- 2018-05-21 IL IL259479A patent/IL259479B/en unknown
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