JP2019500376A5 - - Google Patents

Download PDF

Info

Publication number
JP2019500376A5
JP2019500376A5 JP2018533668A JP2018533668A JP2019500376A5 JP 2019500376 A5 JP2019500376 A5 JP 2019500376A5 JP 2018533668 A JP2018533668 A JP 2018533668A JP 2018533668 A JP2018533668 A JP 2018533668A JP 2019500376 A5 JP2019500376 A5 JP 2019500376A5
Authority
JP
Japan
Prior art keywords
optionally substituted
pharmaceutically acceptable
alkyl
prodrug
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018533668A
Other languages
English (en)
Japanese (ja)
Other versions
JP6995757B2 (ja
JP2019500376A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/068448 external-priority patent/WO2017112909A1/en
Publication of JP2019500376A publication Critical patent/JP2019500376A/ja
Publication of JP2019500376A5 publication Critical patent/JP2019500376A5/ja
Priority to JP2021147955A priority Critical patent/JP2022003045A/ja
Application granted granted Critical
Publication of JP6995757B2 publication Critical patent/JP6995757B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018533668A 2015-12-23 2016-12-22 グルココルチコイド受容体の阻害剤 Expired - Fee Related JP6995757B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021147955A JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562387293P 2015-12-23 2015-12-23
US62/387,293 2015-12-23
PCT/US2016/068448 WO2017112909A1 (en) 2015-12-23 2016-12-22 Inhibitors of glucocorticoid receptor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021147955A Division JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Publications (3)

Publication Number Publication Date
JP2019500376A JP2019500376A (ja) 2019-01-10
JP2019500376A5 true JP2019500376A5 (enExample) 2020-01-30
JP6995757B2 JP6995757B2 (ja) 2022-01-17

Family

ID=59091255

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018533668A Expired - Fee Related JP6995757B2 (ja) 2015-12-23 2016-12-22 グルココルチコイド受容体の阻害剤
JP2021147955A Pending JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021147955A Pending JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Country Status (7)

Country Link
US (1) US11208432B2 (enExample)
EP (1) EP3394079A4 (enExample)
JP (2) JP6995757B2 (enExample)
CN (1) CN108713023B (enExample)
AU (2) AU2016379417B2 (enExample)
CA (1) CA3009525A1 (enExample)
WO (1) WO2017112909A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017112902A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
US11208432B2 (en) 2015-12-23 2021-12-28 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
PL3523315T3 (pl) * 2016-10-07 2021-10-18 Oric Pharmaceuticals, Inc. Inhibitor receptora glukokortykoidowego
CN112272552A (zh) * 2018-04-11 2021-01-26 欧瑞克制药公司 包含糖皮质激素受体拮抗剂的固体形式和制剂及其用途
WO2023185673A1 (zh) * 2022-03-31 2023-10-05 成都赛璟生物医药科技有限公司 一种cdk8抑制剂及其制备方法和用途

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528434B1 (fr) 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
ZA8231B (en) 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (fr) 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
JP2785023B2 (ja) 1987-12-30 1998-08-13 ルセル―ユクラフ 17α位置を置換された17β―OH―19―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物
EP0369881A1 (fr) 1988-11-16 1990-05-23 Roussel-Uclaf Nouveaux produits dérivés de la structure 3-céto delta-4,9 19-nor stéroides et leur application comme médicaments
DE3921059A1 (de) 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
FR2651435A1 (fr) 1989-09-07 1991-03-08 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques.
DE4018167A1 (de) * 1990-06-01 1991-12-05 Schering Ag Verfahren zur herstellung von 10(beta)-h-steroiden
DE4042007A1 (de) 1990-12-22 1992-06-25 Schering Ag 6,7-modifizierte-11(beta)-aryl-4-estrene
EP0712311B1 (en) 1993-08-04 1998-10-07 Akzo Nobel N.V. Antiglucocorticoid steroids for the treatment of anxiety disorders
AU1439595A (en) 1993-12-22 1995-07-10 Salk Institute For Biological Studies, The Methods for reducing multidrug resistance
SK282570B6 (sk) 1995-02-02 2002-10-08 Schering Aktiengesellschaft Antagonisty progesterónu na výrobu liekov na ošetrenie dysfunkčného maternicového krvácania
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
IL122740A (en) 1997-01-15 2003-09-17 Akzo Nobel Nv 16-hydroxy-11-(substituted phenyl)-estra-9,4-diene derivatives, their preparation and pharmaceutical compositions containing them
CN1085078C (zh) * 1998-01-07 2002-05-22 沈志华 用于大月份引产的复合药物
US6512130B1 (en) * 2000-09-05 2003-01-28 Council Of Scientific And Industrial Research Mifepristone analogue, process for the preparation thereof and use thereof
EP1285927A3 (de) 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
US7250408B2 (en) * 2002-12-16 2007-07-31 Bayer Schering Pharma Ag Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility
SI1989218T1 (sl) 2006-02-17 2010-04-30 Janssen Pharmaceutica Nv 17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji
NZ572374A (en) 2006-03-29 2011-12-22 Univ California Diarylthiohydantoin compounds
HRP20160689T1 (hr) 2007-04-20 2016-07-15 Preglem S.A. Selektivni modulatori progesterona za tretman uterinog krvarenja
EP2671086B1 (en) 2011-02-03 2018-04-25 Pop Test Oncology LLC System and method for diagnosis and treatment
EP2545922A1 (en) 2011-07-12 2013-01-16 PregLem S.A. Treatment of excessive menstrual bleeding associated with uterine fibroids
US20130029953A1 (en) 2011-07-28 2013-01-31 Klaus Nickisch Progesterone antagonists
PT3111950T (pt) 2012-02-24 2021-10-19 Univ Chicago Métodos e composições relacionadas com antagonismo recetor de glucocorticoide e cancro da próstata
EP2641602A1 (en) 2012-03-23 2013-09-25 PregLem S.A. Method for treating gynecological diseases
US9096641B2 (en) 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists
WO2015089338A2 (en) 2013-12-11 2015-06-18 Sloan-Kettering Institute For Cancer Research Glucocorticoid inhibitors for treatment of prostate cancer
CN104530166B (zh) 2014-12-04 2016-08-24 陕西汉江药业集团股份有限公司 选择性还原4,6-共轭双烯-3-酮甾体化合物的方法
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
US11208432B2 (en) * 2015-12-23 2021-12-28 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
WO2017112902A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
PL3523315T3 (pl) 2016-10-07 2021-10-18 Oric Pharmaceuticals, Inc. Inhibitor receptora glukokortykoidowego
US12233073B2 (en) 2017-06-09 2025-02-25 Regents Of The University Of Minnesota Skin care formulations and skin cancer treatment
CN112272552A (zh) 2018-04-11 2021-01-26 欧瑞克制药公司 包含糖皮质激素受体拮抗剂的固体形式和制剂及其用途

Similar Documents

Publication Publication Date Title
JP2019524883A5 (enExample)
JP2019500374A5 (enExample)
JP2018522879A5 (enExample)
JP2018504437A5 (enExample)
JP2019522055A5 (enExample)
JP2017501237A5 (enExample)
JP2017512833A5 (enExample)
JP2016503799A5 (enExample)
JP2016506369A5 (enExample)
JP2019518766A5 (enExample)
JP2017511815A5 (enExample)
JP2017071634A5 (enExample)
JP2015520769A5 (enExample)
JP2017504635A5 (enExample)
JP2015531366A5 (enExample)
JP2017537937A5 (enExample)
JP2015509534A5 (enExample)
JP2017508782A5 (enExample)
JP2016537366A5 (enExample)
JP2014503574A5 (enExample)
JP2017526677A5 (enExample)
JP2017538773A5 (enExample)
JP2019501130A5 (enExample)
JP2019500387A5 (enExample)
JP2015508092A5 (enExample)