JP2019500376A5 - - Google Patents

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Publication number
JP2019500376A5
JP2019500376A5 JP2018533668A JP2018533668A JP2019500376A5 JP 2019500376 A5 JP2019500376 A5 JP 2019500376A5 JP 2018533668 A JP2018533668 A JP 2018533668A JP 2018533668 A JP2018533668 A JP 2018533668A JP 2019500376 A5 JP2019500376 A5 JP 2019500376A5
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JP
Japan
Prior art keywords
optionally substituted
pharmaceutically acceptable
alkyl
prodrug
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018533668A
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English (en)
Japanese (ja)
Other versions
JP6995757B2 (ja
JP2019500376A (ja
Filing date
Publication date
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Priority claimed from PCT/US2016/068448 external-priority patent/WO2017112909A1/en
Publication of JP2019500376A publication Critical patent/JP2019500376A/ja
Publication of JP2019500376A5 publication Critical patent/JP2019500376A5/ja
Priority to JP2021147955A priority Critical patent/JP2022003045A/ja
Application granted granted Critical
Publication of JP6995757B2 publication Critical patent/JP6995757B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018533668A 2015-12-23 2016-12-22 グルココルチコイド受容体の阻害剤 Expired - Fee Related JP6995757B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021147955A JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562387293P 2015-12-23 2015-12-23
US62/387,293 2015-12-23
PCT/US2016/068448 WO2017112909A1 (en) 2015-12-23 2016-12-22 Inhibitors of glucocorticoid receptor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021147955A Division JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Publications (3)

Publication Number Publication Date
JP2019500376A JP2019500376A (ja) 2019-01-10
JP2019500376A5 true JP2019500376A5 (enExample) 2020-01-30
JP6995757B2 JP6995757B2 (ja) 2022-01-17

Family

ID=59091255

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018533668A Expired - Fee Related JP6995757B2 (ja) 2015-12-23 2016-12-22 グルココルチコイド受容体の阻害剤
JP2021147955A Pending JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021147955A Pending JP2022003045A (ja) 2015-12-23 2021-09-10 グルココルチコイド受容体の阻害剤

Country Status (7)

Country Link
US (1) US11208432B2 (enExample)
EP (1) EP3394079A4 (enExample)
JP (2) JP6995757B2 (enExample)
CN (1) CN108713023B (enExample)
AU (2) AU2016379417B2 (enExample)
CA (1) CA3009525A1 (enExample)
WO (1) WO2017112909A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017112909A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
WO2017112904A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6906525B2 (ja) 2015-12-23 2021-07-21 オリック ファーマシューティカルズ,インク. グルココルチコイド受容体の阻害剤
CN110099915A (zh) * 2016-10-07 2019-08-06 欧瑞克制药公司 糖皮质激素受体抑制剂
WO2019200156A1 (en) * 2018-04-11 2019-10-17 Oric Pharmaceuticals, Inc. Solid forms and formulations comprising a glucocorticoid receptor antagonist and uses thereof
CN118265717A (zh) * 2022-03-31 2024-06-28 成都赛璟生物医药科技有限公司 一种cdk8抑制剂及其制备方法和用途

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FR2522328B1 (fr) 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
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JPH02188599A (ja) 1988-11-16 1990-07-24 Roussel Uclaf 3―ケト―デルタ―4,9―19―ノルステロイドから誘導される新物質及びそれらよりなる薬剤
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DE4018167A1 (de) * 1990-06-01 1991-12-05 Schering Ag Verfahren zur herstellung von 10(beta)-h-steroiden
DE4042007A1 (de) 1990-12-22 1992-06-25 Schering Ag 6,7-modifizierte-11(beta)-aryl-4-estrene
US5741787A (en) 1993-08-04 1998-04-21 Akzo Nobel N.V. Antiglucocorticoid steroids for the treatment of anxiety disorders
AU1439595A (en) 1993-12-22 1995-07-10 Salk Institute For Biological Studies, The Methods for reducing multidrug resistance
DK0806952T3 (da) 1995-02-02 2003-06-16 Schering Ag Progesteronantagonister til fremstillingen af lægemidler til behandling af dysfunktionelle uterine blødninger
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
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CN101421290B (zh) 2006-02-17 2012-09-19 詹森药业有限公司 用作孕酮受体调节剂的17-磷类固醇衍生物
CA2648139A1 (en) 2006-03-29 2007-11-08 The Regents Of The University Of California Diaryl thiohydantoin compounds and their use in the treatment of hyperproliferative disorders
US8569274B2 (en) 2007-04-20 2013-10-29 Preglem S.A. Progesterone antagonist and selective progesterone modulator in the treatment of excessive uterine bleeding
WO2012106514A2 (en) 2011-02-03 2012-08-09 Pop Test Cortisol Llc System and method for diagnosis and treatment
EP2545922A1 (en) 2011-07-12 2013-01-16 PregLem S.A. Treatment of excessive menstrual bleeding associated with uterine fibroids
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DK3111950T3 (da) 2012-02-24 2021-10-04 Univ Chicago Fremgangsmåder og sammensætninger relateret til glucocorticoidreceptorantagonisme og prostatacancer
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EP3079475B1 (en) 2013-12-11 2020-10-07 Sloan-kettering Institute For Cancer Research Glucocorticoid inhibitors for treatment of prostate cancer
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WO2017112904A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6906525B2 (ja) 2015-12-23 2021-07-21 オリック ファーマシューティカルズ,インク. グルココルチコイド受容体の阻害剤
WO2017112909A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
CN110099915A (zh) 2016-10-07 2019-08-06 欧瑞克制药公司 糖皮质激素受体抑制剂
US12233073B2 (en) 2017-06-09 2025-02-25 Regents Of The University Of Minnesota Skin care formulations and skin cancer treatment
WO2019200156A1 (en) 2018-04-11 2019-10-17 Oric Pharmaceuticals, Inc. Solid forms and formulations comprising a glucocorticoid receptor antagonist and uses thereof

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