JP2018537517A5 - - Google Patents

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Publication number
JP2018537517A5
JP2018537517A5 JP2018535221A JP2018535221A JP2018537517A5 JP 2018537517 A5 JP2018537517 A5 JP 2018537517A5 JP 2018535221 A JP2018535221 A JP 2018535221A JP 2018535221 A JP2018535221 A JP 2018535221A JP 2018537517 A5 JP2018537517 A5 JP 2018537517A5
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JP
Japan
Prior art keywords
group
pharmaceutically acceptable
combination
acceptable salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018535221A
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English (en)
Japanese (ja)
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JP2018537517A (ja
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Publication date
Priority claimed from PCT/CN2016/078039 external-priority patent/WO2017084234A1/zh
Application filed filed Critical
Priority claimed from PCT/CN2016/100187 external-priority patent/WO2017050298A1/en
Publication of JP2018537517A publication Critical patent/JP2018537517A/ja
Publication of JP2018537517A5 publication Critical patent/JP2018537517A5/ja
Priority to JP2021176691A priority Critical patent/JP7261850B2/ja
Pending legal-status Critical Current

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JP2018535221A 2015-09-24 2016-09-26 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用 Pending JP2018537517A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021176691A JP7261850B2 (ja) 2015-09-24 2021-10-28 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562222959P 2015-09-24 2015-09-24
US62/222,959 2015-09-24
US201562257697P 2015-11-19 2015-11-19
US62/257,697 2015-11-19
PCT/CN2016/078039 WO2017084234A1 (zh) 2015-11-19 2016-03-31 预防或治疗脂肪肝的药物组合物
CNPCT/CN2016/078039 2016-03-31
PCT/CN2016/100187 WO2017050298A1 (en) 2015-09-24 2016-09-26 Compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021176691A Division JP7261850B2 (ja) 2015-09-24 2021-10-28 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用

Publications (2)

Publication Number Publication Date
JP2018537517A JP2018537517A (ja) 2018-12-20
JP2018537517A5 true JP2018537517A5 (enExample) 2019-11-07

Family

ID=60047309

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018535221A Pending JP2018537517A (ja) 2015-09-24 2016-09-26 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用
JP2021176691A Active JP7261850B2 (ja) 2015-09-24 2021-10-28 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021176691A Active JP7261850B2 (ja) 2015-09-24 2021-10-28 肝毒性および脂肪性肝疾患の処置に有効な化合物およびその使用

Country Status (20)

Country Link
US (4) US10456371B2 (enExample)
EP (3) EP4609911A3 (enExample)
JP (2) JP2018537517A (enExample)
KR (2) KR20240042148A (enExample)
CN (3) CN107614475A (enExample)
AU (3) AU2016327930B2 (enExample)
BR (1) BR112018005905B1 (enExample)
CA (2) CA2999368A1 (enExample)
EA (1) EA201890810A1 (enExample)
ES (1) ES3044383T3 (enExample)
HK (1) HK1244266A1 (enExample)
HR (1) HRP20250899T1 (enExample)
HU (1) HUE072982T2 (enExample)
MX (2) MX395231B (enExample)
MY (1) MY190647A (enExample)
PH (1) PH12018500659A1 (enExample)
SG (1) SG10202002573RA (enExample)
TW (1) TWI781912B (enExample)
WO (1) WO2017050298A1 (enExample)
ZA (1) ZA201802373B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016520100A (ja) * 2013-11-13 2016-07-11 ▲財▼▲団▼法人国防教育研究基金会National Defense Education And Research Foundation 肝臓に対する副作用がない、新しいアセトアミノフェン複合組成
ES3044383T3 (en) 2015-09-24 2025-11-26 Sinew Pharma Inc Mannitol for use in treating hepatotoxicity and fatty liver diseases
TWI711464B (zh) * 2015-11-19 2020-12-01 欣耀生醫股份有限公司 預防或治療脂肪肝、保護肝功能、或改善脂肪肝引起的肝病變或其他相關病症之組合物及方法
SG11202007314QA (en) * 2018-02-14 2020-08-28 Sinew Pharma Inc Methods and compositions for preventing, reducing or eradicating toxicity caused by acetaminophen (apap)
CN110538187A (zh) * 2018-05-28 2019-12-06 北京大学 Cpt1激活剂
KR102136326B1 (ko) * 2018-09-06 2020-07-22 서울대학교산학협력단 가시박으로부터 분리한 플라보노이드 유도체를 유효성분으로 포함하는 간 질환 예방 또는 치료용 조성물
TWI691719B (zh) * 2018-10-19 2020-04-21 香港商阿瓦隆 海帕波有限公司 半乳糖快速定量檢測系統及其應用
CN109920550A (zh) * 2018-12-25 2019-06-21 天津大学 一种基于dMRI研究青少年肌阵挛性癫痫的方法
AU2020211695A1 (en) * 2019-01-21 2021-09-02 National University Of Singapore Treatment of hepatotoxicity
CN110269855A (zh) * 2019-07-19 2019-09-24 辽宁大学 黄酮类小分子化合物在制备抑制胰脂肪酶活性药物中的应用
US12383191B1 (en) * 2020-05-04 2025-08-12 PathAI, Inc. Systems and methods for assessing liver pathology
CN113999272A (zh) * 2021-10-29 2022-02-01 广西医科大学 香蜂草苷的制备方法及其应用
CN113875982A (zh) * 2021-11-19 2022-01-04 武汉森澜生物科技有限公司 一种含二氢杨梅素的抗衰组合物及其应用
CN117482082A (zh) * 2023-11-27 2024-02-02 西北大学 金松双黄酮在制备抗慢性肾损伤药物中的应用

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
US4661519A (en) * 1983-04-12 1987-04-28 Pola Chemical Industries Inc. Method for dermatological application
CH664150A5 (de) * 1985-01-15 1988-02-15 Peter Paul Prof Dr Speiser Fumarsaeureprodrug, verfahren zu seiner herstellung und dieses enthaltende darreichungsformen.
JP3916685B2 (ja) * 1996-02-29 2007-05-16 第一製薬株式会社 ガラクトース誘導体
JP4677550B2 (ja) * 2002-08-14 2011-04-27 独立行政法人産業技術総合研究所 環状エステル化合物
TWI287990B (en) * 2004-01-08 2007-10-11 Nat Defense Medical Ct Inhibitors and enhancers of uridine diphosphate-glucuronosyl transferase 2B (UGT2B)
US20070009441A1 (en) * 2004-07-08 2007-01-11 Molecular Therapeutics, Inc. Biodegradable nanoparticles
CN1939929A (zh) * 2005-09-29 2007-04-04 云南白药集团股份有限公司 一种偏诺皂苷类化合物酸式盐及制备方法
CN108465110A (zh) * 2011-04-20 2018-08-31 教育研究基金会 无/低副作用的抗结核病药物复方
US20150291721A1 (en) * 2012-11-12 2015-10-15 Segetis, Inc. Crosslinkable polyketal esters, methods of manufacture and uses thereof
US9211298B2 (en) * 2012-11-16 2015-12-15 Song Gao Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses
US9149491B2 (en) * 2013-04-29 2015-10-06 Harsha Chigurupati Reduced toxicity in alcoholic beverages
TWI552748B (zh) 2013-10-25 2016-10-11 The use of a compound for the removal of hepatotoxicity against Acetaminophen (APAP)
CN104623670A (zh) * 2013-11-06 2015-05-20 高松 一种含西红花素的组合物及其应用
JP2016520100A (ja) * 2013-11-13 2016-07-11 ▲財▼▲団▼法人国防教育研究基金会National Defense Education And Research Foundation 肝臓に対する副作用がない、新しいアセトアミノフェン複合組成
CN104292289B (zh) * 2014-07-10 2017-12-29 程怡 半乳糖配体及其在肝靶向脂质体中的应用
ES3044383T3 (en) * 2015-09-24 2025-11-26 Sinew Pharma Inc Mannitol for use in treating hepatotoxicity and fatty liver diseases
TWI711464B (zh) * 2015-11-19 2020-12-01 欣耀生醫股份有限公司 預防或治療脂肪肝、保護肝功能、或改善脂肪肝引起的肝病變或其他相關病症之組合物及方法

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