JP2018537440A5 - - Google Patents
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- JP2018537440A5 JP2018537440A5 JP2018523011A JP2018523011A JP2018537440A5 JP 2018537440 A5 JP2018537440 A5 JP 2018537440A5 JP 2018523011 A JP2018523011 A JP 2018523011A JP 2018523011 A JP2018523011 A JP 2018523011A JP 2018537440 A5 JP2018537440 A5 JP 2018537440A5
- Authority
- JP
- Japan
- Prior art keywords
- msc
- donor
- small
- mscs
- ssea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000004113 cell culture Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 5
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 5
- 210000002744 extracellular matrix Anatomy 0.000 claims 5
- 238000002955 isolation Methods 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 230000032683 aging Effects 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000007747 plating Methods 0.000 claims 1
- 238000009168 stem cell therapy Methods 0.000 claims 1
- 238000009580 stem-cell therapy Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021066352A JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250664P | 2015-11-04 | 2015-11-04 | |
| US62/250,664 | 2015-11-04 | ||
| PCT/US2016/060624 WO2017079621A1 (en) | 2015-11-04 | 2016-11-04 | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Division JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537440A JP2018537440A (ja) | 2018-12-20 |
| JP2018537440A5 true JP2018537440A5 (enExample) | 2019-12-12 |
| JP6871637B2 JP6871637B2 (ja) | 2021-05-12 |
Family
ID=58662777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018523011A Active JP6871637B2 (ja) | 2015-11-04 | 2016-11-04 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11802272B2 (enExample) |
| EP (1) | EP3370740A4 (enExample) |
| JP (2) | JP6871637B2 (enExample) |
| CN (1) | CN108601799A (enExample) |
| AU (1) | AU2016349701B2 (enExample) |
| CA (1) | CA3004296A1 (enExample) |
| HK (1) | HK1254739A1 (enExample) |
| WO (1) | WO2017079621A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190153386A1 (en) * | 2017-11-17 | 2019-05-23 | James R. Musick | Stem cell line for treatment of various medical conditions |
| CN113166722A (zh) | 2018-10-03 | 2021-07-23 | 斯特姆生物系统有限公司 | 羊水细胞来源的细胞外基质及其用途 |
| KR102639023B1 (ko) | 2019-02-21 | 2024-02-20 | 스템바이오시스, 인크. | 양수 세포-유래 ecm 상에서 심근세포 성숙을 위한 방법, 세포 구조, 및 약물 화합물의 심장 독성 및 전부정맥 스크리닝을 위한 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807458B2 (en) * | 2003-01-30 | 2010-10-05 | The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs | Multilineage-inducible cells and uses thereof |
| US9155762B2 (en) * | 2005-12-08 | 2015-10-13 | University Of Louisville Research Foundation, Inc. | Uses and isolation of stem cells from bone marrow |
| EP2535403B1 (en) | 2005-12-08 | 2019-06-19 | University Of Louisville Research Foundation, Inc. | Very small embryonic-like (VSEL) stem cells and methods of isolating and using the same |
| US8084023B2 (en) | 2007-01-22 | 2011-12-27 | The Board Of Trustees Of The University Of Arkansas | Maintenance and propagation of mesenchymal stem cells |
| CN102333861A (zh) * | 2008-09-30 | 2012-01-25 | 路易斯维尔大学研究基金会有限公司 | 用于分离非常小的胚胎样(vsel)干细胞的方法 |
| BRPI0924921A2 (pt) | 2009-03-31 | 2015-07-07 | Univ Texas | Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados |
| EP2614145B1 (en) | 2010-09-07 | 2020-12-02 | The Board of Regents of The University of Texas System | Tissue-specific differentiation matrices and uses thereof |
| WO2012135838A1 (en) * | 2011-04-01 | 2012-10-04 | University Of Louisville Research Foundation, Inc. | Methods and compositions for large-scale isolation of very small embryonic-like (vsel) stem cells |
| CA2857545A1 (en) * | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| US20170335286A1 (en) | 2014-10-30 | 2017-11-23 | Stembiosys, Inc. | Methods for maintaining and expanding mesenchymal stem cells on extracellular matrix coated microcarriers |
-
2016
- 2016-11-04 HK HK18113751.2A patent/HK1254739A1/zh unknown
- 2016-11-04 AU AU2016349701A patent/AU2016349701B2/en active Active
- 2016-11-04 US US15/773,520 patent/US11802272B2/en active Active
- 2016-11-04 EP EP16863074.7A patent/EP3370740A4/en not_active Withdrawn
- 2016-11-04 CA CA3004296A patent/CA3004296A1/en not_active Abandoned
- 2016-11-04 WO PCT/US2016/060624 patent/WO2017079621A1/en not_active Ceased
- 2016-11-04 CN CN201680077403.3A patent/CN108601799A/zh active Pending
- 2016-11-04 JP JP2018523011A patent/JP6871637B2/ja active Active
-
2021
- 2021-04-09 JP JP2021066352A patent/JP7153951B2/ja active Active
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