JP2018537440A5 - - Google Patents
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- JP2018537440A5 JP2018537440A5 JP2018523011A JP2018523011A JP2018537440A5 JP 2018537440 A5 JP2018537440 A5 JP 2018537440A5 JP 2018523011 A JP2018523011 A JP 2018523011A JP 2018523011 A JP2018523011 A JP 2018523011A JP 2018537440 A5 JP2018537440 A5 JP 2018537440A5
- Authority
- JP
- Japan
- Prior art keywords
- msc
- donor
- small
- mscs
- ssea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000004113 cell culture Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 5
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 5
- 210000002744 extracellular matrix Anatomy 0.000 claims 5
- 238000002955 isolation Methods 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 230000032683 aging Effects 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000007747 plating Methods 0.000 claims 1
- 238000009168 stem cell therapy Methods 0.000 claims 1
- 238000009580 stem-cell therapy Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021066352A JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250664P | 2015-11-04 | 2015-11-04 | |
| US62/250,664 | 2015-11-04 | ||
| PCT/US2016/060624 WO2017079621A1 (en) | 2015-11-04 | 2016-11-04 | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Division JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537440A JP2018537440A (ja) | 2018-12-20 |
| JP2018537440A5 true JP2018537440A5 (enExample) | 2019-12-12 |
| JP6871637B2 JP6871637B2 (ja) | 2021-05-12 |
Family
ID=58662777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018523011A Active JP6871637B2 (ja) | 2015-11-04 | 2016-11-04 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11802272B2 (enExample) |
| EP (1) | EP3370740A4 (enExample) |
| JP (2) | JP6871637B2 (enExample) |
| CN (1) | CN108601799A (enExample) |
| AU (1) | AU2016349701B2 (enExample) |
| CA (1) | CA3004296A1 (enExample) |
| HK (1) | HK1254739A1 (enExample) |
| WO (1) | WO2017079621A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190153386A1 (en) * | 2017-11-17 | 2019-05-23 | James R. Musick | Stem cell line for treatment of various medical conditions |
| CN113166722A (zh) | 2018-10-03 | 2021-07-23 | 斯特姆生物系统有限公司 | 羊水细胞来源的细胞外基质及其用途 |
| CN113728092B (zh) | 2019-02-21 | 2025-04-22 | 斯特姆生物系统有限公司 | 心肌细胞在羊水细胞来源的ecm上成熟化的方法、细胞构建体及用于药物化合物的心脏毒性和致心律失常筛查的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807458B2 (en) * | 2003-01-30 | 2010-10-05 | The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs | Multilineage-inducible cells and uses thereof |
| US9155762B2 (en) * | 2005-12-08 | 2015-10-13 | University Of Louisville Research Foundation, Inc. | Uses and isolation of stem cells from bone marrow |
| CN101573441A (zh) * | 2005-12-08 | 2009-11-04 | 路易斯维尔大学研究基金会有限公司 | 非常小的胚胎样(vsel)干细胞及分离和利用其的方法 |
| US8084023B2 (en) | 2007-01-22 | 2011-12-27 | The Board Of Trustees Of The University Of Arkansas | Maintenance and propagation of mesenchymal stem cells |
| CN102333861A (zh) * | 2008-09-30 | 2012-01-25 | 路易斯维尔大学研究基金会有限公司 | 用于分离非常小的胚胎样(vsel)干细胞的方法 |
| KR20120003470A (ko) | 2009-03-31 | 2012-01-10 | 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 사람 제대혈 유래의 중간엽 줄기 세포의 분리 |
| AU2011299327B2 (en) | 2010-09-07 | 2015-07-16 | The Board Of Regents Of The University Of Texas System | Tissue-specific differentiation matrices and uses thereof |
| EP2694651A4 (en) | 2011-04-01 | 2014-11-26 | Univ Louisville Res Found | METHOD AND COMPOSITIONS FOR THE LARGE INSULATION OF VERY SMALL EMBRYONAL-SIMILAR STEM CELLS |
| PL2785359T3 (pl) * | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| US20170335286A1 (en) | 2014-10-30 | 2017-11-23 | Stembiosys, Inc. | Methods for maintaining and expanding mesenchymal stem cells on extracellular matrix coated microcarriers |
-
2016
- 2016-11-04 CA CA3004296A patent/CA3004296A1/en not_active Abandoned
- 2016-11-04 CN CN201680077403.3A patent/CN108601799A/zh active Pending
- 2016-11-04 JP JP2018523011A patent/JP6871637B2/ja active Active
- 2016-11-04 HK HK18113751.2A patent/HK1254739A1/zh unknown
- 2016-11-04 AU AU2016349701A patent/AU2016349701B2/en not_active Ceased
- 2016-11-04 US US15/773,520 patent/US11802272B2/en active Active
- 2016-11-04 WO PCT/US2016/060624 patent/WO2017079621A1/en not_active Ceased
- 2016-11-04 EP EP16863074.7A patent/EP3370740A4/en not_active Withdrawn
-
2021
- 2021-04-09 JP JP2021066352A patent/JP7153951B2/ja active Active
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