JP6871637B2 - 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 - Google Patents
高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 Download PDFInfo
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- JP6871637B2 JP6871637B2 JP2018523011A JP2018523011A JP6871637B2 JP 6871637 B2 JP6871637 B2 JP 6871637B2 JP 2018523011 A JP2018523011 A JP 2018523011A JP 2018523011 A JP2018523011 A JP 2018523011A JP 6871637 B2 JP6871637 B2 JP 6871637B2
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
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- Developmental Biology & Embryology (AREA)
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- Physical Education & Sports Medicine (AREA)
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- Biotechnology (AREA)
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- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021066352A JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250664P | 2015-11-04 | 2015-11-04 | |
| US62/250,664 | 2015-11-04 | ||
| PCT/US2016/060624 WO2017079621A1 (en) | 2015-11-04 | 2016-11-04 | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Division JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537440A JP2018537440A (ja) | 2018-12-20 |
| JP2018537440A5 JP2018537440A5 (enExample) | 2019-12-12 |
| JP6871637B2 true JP6871637B2 (ja) | 2021-05-12 |
Family
ID=58662777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018523011A Active JP6871637B2 (ja) | 2015-11-04 | 2016-11-04 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021066352A Active JP7153951B2 (ja) | 2015-11-04 | 2021-04-09 | 高齢細胞集団由来の高い分化能を有するヒト間葉系幹細胞の濃縮および増幅 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11802272B2 (enExample) |
| EP (1) | EP3370740A4 (enExample) |
| JP (2) | JP6871637B2 (enExample) |
| CN (1) | CN108601799A (enExample) |
| AU (1) | AU2016349701B2 (enExample) |
| CA (1) | CA3004296A1 (enExample) |
| HK (1) | HK1254739A1 (enExample) |
| WO (1) | WO2017079621A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190153386A1 (en) * | 2017-11-17 | 2019-05-23 | James R. Musick | Stem cell line for treatment of various medical conditions |
| CN113166722A (zh) | 2018-10-03 | 2021-07-23 | 斯特姆生物系统有限公司 | 羊水细胞来源的细胞外基质及其用途 |
| KR102639023B1 (ko) | 2019-02-21 | 2024-02-20 | 스템바이오시스, 인크. | 양수 세포-유래 ecm 상에서 심근세포 성숙을 위한 방법, 세포 구조, 및 약물 화합물의 심장 독성 및 전부정맥 스크리닝을 위한 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807458B2 (en) * | 2003-01-30 | 2010-10-05 | The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs | Multilineage-inducible cells and uses thereof |
| US9155762B2 (en) * | 2005-12-08 | 2015-10-13 | University Of Louisville Research Foundation, Inc. | Uses and isolation of stem cells from bone marrow |
| EP2535403B1 (en) | 2005-12-08 | 2019-06-19 | University Of Louisville Research Foundation, Inc. | Very small embryonic-like (VSEL) stem cells and methods of isolating and using the same |
| US8084023B2 (en) | 2007-01-22 | 2011-12-27 | The Board Of Trustees Of The University Of Arkansas | Maintenance and propagation of mesenchymal stem cells |
| CN102333861A (zh) * | 2008-09-30 | 2012-01-25 | 路易斯维尔大学研究基金会有限公司 | 用于分离非常小的胚胎样(vsel)干细胞的方法 |
| BRPI0924921A2 (pt) | 2009-03-31 | 2015-07-07 | Univ Texas | Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados |
| EP2614145B1 (en) | 2010-09-07 | 2020-12-02 | The Board of Regents of The University of Texas System | Tissue-specific differentiation matrices and uses thereof |
| WO2012135838A1 (en) * | 2011-04-01 | 2012-10-04 | University Of Louisville Research Foundation, Inc. | Methods and compositions for large-scale isolation of very small embryonic-like (vsel) stem cells |
| CA2857545A1 (en) * | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| US20170335286A1 (en) | 2014-10-30 | 2017-11-23 | Stembiosys, Inc. | Methods for maintaining and expanding mesenchymal stem cells on extracellular matrix coated microcarriers |
-
2016
- 2016-11-04 HK HK18113751.2A patent/HK1254739A1/zh unknown
- 2016-11-04 AU AU2016349701A patent/AU2016349701B2/en active Active
- 2016-11-04 US US15/773,520 patent/US11802272B2/en active Active
- 2016-11-04 EP EP16863074.7A patent/EP3370740A4/en not_active Withdrawn
- 2016-11-04 CA CA3004296A patent/CA3004296A1/en not_active Abandoned
- 2016-11-04 WO PCT/US2016/060624 patent/WO2017079621A1/en not_active Ceased
- 2016-11-04 CN CN201680077403.3A patent/CN108601799A/zh active Pending
- 2016-11-04 JP JP2018523011A patent/JP6871637B2/ja active Active
-
2021
- 2021-04-09 JP JP2021066352A patent/JP7153951B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HK1254739A1 (zh) | 2019-07-26 |
| AU2016349701A1 (en) | 2018-05-24 |
| CA3004296A1 (en) | 2017-05-11 |
| CN108601799A (zh) | 2018-09-28 |
| AU2016349701B2 (en) | 2023-10-19 |
| US20180320140A1 (en) | 2018-11-08 |
| EP3370740A4 (en) | 2019-05-22 |
| US11802272B2 (en) | 2023-10-31 |
| EP3370740A1 (en) | 2018-09-12 |
| WO2017079621A1 (en) | 2017-05-11 |
| JP2018537440A (ja) | 2018-12-20 |
| JP7153951B2 (ja) | 2022-10-17 |
| JP2021105047A (ja) | 2021-07-26 |
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