AU2016349701B2 - Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations - Google Patents
Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations Download PDFInfo
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- AU2016349701B2 AU2016349701B2 AU2016349701A AU2016349701A AU2016349701B2 AU 2016349701 B2 AU2016349701 B2 AU 2016349701B2 AU 2016349701 A AU2016349701 A AU 2016349701A AU 2016349701 A AU2016349701 A AU 2016349701A AU 2016349701 B2 AU2016349701 B2 AU 2016349701B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250664P | 2015-11-04 | 2015-11-04 | |
| US62/250,664 | 2015-11-04 | ||
| PCT/US2016/060624 WO2017079621A1 (en) | 2015-11-04 | 2016-11-04 | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2016349701A1 AU2016349701A1 (en) | 2018-05-24 |
| AU2016349701B2 true AU2016349701B2 (en) | 2023-10-19 |
Family
ID=58662777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016349701A Active AU2016349701B2 (en) | 2015-11-04 | 2016-11-04 | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11802272B2 (enExample) |
| EP (1) | EP3370740A4 (enExample) |
| JP (2) | JP6871637B2 (enExample) |
| CN (1) | CN108601799A (enExample) |
| AU (1) | AU2016349701B2 (enExample) |
| CA (1) | CA3004296A1 (enExample) |
| HK (1) | HK1254739A1 (enExample) |
| WO (1) | WO2017079621A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190153386A1 (en) * | 2017-11-17 | 2019-05-23 | James R. Musick | Stem cell line for treatment of various medical conditions |
| CN113166722A (zh) | 2018-10-03 | 2021-07-23 | 斯特姆生物系统有限公司 | 羊水细胞来源的细胞外基质及其用途 |
| KR102639023B1 (ko) | 2019-02-21 | 2024-02-20 | 스템바이오시스, 인크. | 양수 세포-유래 ecm 상에서 심근세포 성숙을 위한 방법, 세포 구조, 및 약물 화합물의 심장 독성 및 전부정맥 스크리닝을 위한 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807458B2 (en) * | 2003-01-30 | 2010-10-05 | The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs | Multilineage-inducible cells and uses thereof |
| US9155762B2 (en) * | 2005-12-08 | 2015-10-13 | University Of Louisville Research Foundation, Inc. | Uses and isolation of stem cells from bone marrow |
| EP2535403B1 (en) | 2005-12-08 | 2019-06-19 | University Of Louisville Research Foundation, Inc. | Very small embryonic-like (VSEL) stem cells and methods of isolating and using the same |
| US8084023B2 (en) | 2007-01-22 | 2011-12-27 | The Board Of Trustees Of The University Of Arkansas | Maintenance and propagation of mesenchymal stem cells |
| CN102333861A (zh) * | 2008-09-30 | 2012-01-25 | 路易斯维尔大学研究基金会有限公司 | 用于分离非常小的胚胎样(vsel)干细胞的方法 |
| BRPI0924921A2 (pt) | 2009-03-31 | 2015-07-07 | Univ Texas | Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados |
| EP2614145B1 (en) | 2010-09-07 | 2020-12-02 | The Board of Regents of The University of Texas System | Tissue-specific differentiation matrices and uses thereof |
| WO2012135838A1 (en) * | 2011-04-01 | 2012-10-04 | University Of Louisville Research Foundation, Inc. | Methods and compositions for large-scale isolation of very small embryonic-like (vsel) stem cells |
| CA2857545A1 (en) * | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| US20170335286A1 (en) | 2014-10-30 | 2017-11-23 | Stembiosys, Inc. | Methods for maintaining and expanding mesenchymal stem cells on extracellular matrix coated microcarriers |
-
2016
- 2016-11-04 HK HK18113751.2A patent/HK1254739A1/zh unknown
- 2016-11-04 AU AU2016349701A patent/AU2016349701B2/en active Active
- 2016-11-04 US US15/773,520 patent/US11802272B2/en active Active
- 2016-11-04 EP EP16863074.7A patent/EP3370740A4/en not_active Withdrawn
- 2016-11-04 CA CA3004296A patent/CA3004296A1/en not_active Abandoned
- 2016-11-04 WO PCT/US2016/060624 patent/WO2017079621A1/en not_active Ceased
- 2016-11-04 CN CN201680077403.3A patent/CN108601799A/zh active Pending
- 2016-11-04 JP JP2018523011A patent/JP6871637B2/ja active Active
-
2021
- 2021-04-09 JP JP2021066352A patent/JP7153951B2/ja active Active
Non-Patent Citations (2)
| Title |
|---|
| Hall, S.R.R. et al., Stem Cells Translational Medicine. 2013, Vol. 2, No. 8, pages 567-578 * |
| Igura, K. et al., AMERICAN JOURNAL OF PHYSIOLOGY - HEART AND CIRCULATORY PHYSIOLOGY. 2013, Vol. 305, No. 9, pages H1354-H1362 * |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1254739A1 (zh) | 2019-07-26 |
| JP6871637B2 (ja) | 2021-05-12 |
| AU2016349701A1 (en) | 2018-05-24 |
| CA3004296A1 (en) | 2017-05-11 |
| CN108601799A (zh) | 2018-09-28 |
| US20180320140A1 (en) | 2018-11-08 |
| EP3370740A4 (en) | 2019-05-22 |
| US11802272B2 (en) | 2023-10-31 |
| EP3370740A1 (en) | 2018-09-12 |
| WO2017079621A1 (en) | 2017-05-11 |
| JP2018537440A (ja) | 2018-12-20 |
| JP7153951B2 (ja) | 2022-10-17 |
| JP2021105047A (ja) | 2021-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |