JP2018531583A5 - - Google Patents
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- Publication number
- JP2018531583A5 JP2018531583A5 JP2018506601A JP2018506601A JP2018531583A5 JP 2018531583 A5 JP2018531583 A5 JP 2018531583A5 JP 2018506601 A JP2018506601 A JP 2018506601A JP 2018506601 A JP2018506601 A JP 2018506601A JP 2018531583 A5 JP2018531583 A5 JP 2018531583A5
- Authority
- JP
- Japan
- Prior art keywords
- free dna
- dna fragments
- cell
- sequence
- subsequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021060027A JP7506408B2 (ja) | 2015-08-12 | 2021-03-31 | 血漿ｄｎａの単分子配列決定 |
| JP2024092950A JP7810455B2 (ja) | 2015-08-12 | 2024-06-07 | 血漿ｄｎａの単分子配列決定 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562204396P | 2015-08-12 | 2015-08-12 | |
| US62/204,396 | 2015-08-12 | ||
| PCT/CN2016/094802 WO2017025059A1 (en) | 2015-08-12 | 2016-08-12 | Single-molecule sequencing of plasma dna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021060027A Division JP7506408B2 (ja) | 2015-08-12 | 2021-03-31 | 血漿ｄｎａの単分子配列決定 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531583A JP2018531583A (ja) | 2018-11-01 |
| JP2018531583A5 true JP2018531583A5 (enExample) | 2019-09-05 |
| JP6867045B2 JP6867045B2 (ja) | 2021-04-28 |
Family
ID=57983895
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506601A Active JP6867045B2 (ja) | 2015-08-12 | 2016-08-12 | 血漿ｄｎａの単分子配列決定 |
| JP2021060027A Active JP7506408B2 (ja) | 2015-08-12 | 2021-03-31 | 血漿ｄｎａの単分子配列決定 |
| JP2024092950A Active JP7810455B2 (ja) | 2015-08-12 | 2024-06-07 | 血漿ｄｎａの単分子配列決定 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021060027A Active JP7506408B2 (ja) | 2015-08-12 | 2021-03-31 | 血漿ｄｎａの単分子配列決定 |
| JP2024092950A Active JP7810455B2 (ja) | 2015-08-12 | 2024-06-07 | 血漿ｄｎａの単分子配列決定 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11319586B2 (enExample) |
| EP (1) | EP3334843A4 (enExample) |
| JP (3) | JP6867045B2 (enExample) |
| CN (2) | CN115433769A (enExample) |
| AU (3) | AU2016305103C1 (enExample) |
| CA (1) | CA2995422A1 (enExample) |
| HK (1) | HK1248286A1 (enExample) |
| IL (3) | IL285795B (enExample) |
| MY (1) | MY188348A (enExample) |
| SA (1) | SA518390907B1 (enExample) |
| TW (2) | TWI728994B (enExample) |
| WO (1) | WO2017025059A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7084470B2 (ja) | 2017-08-23 | 2022-06-14 | エフ．ホフマン－ラ ロシュ アーゲー | 酵素のスクリーニング法 |
| KR20200060410A (ko) * | 2017-09-07 | 2020-05-29 | 쿠퍼제노믹스, 인크. | 비침습적 착상전 유전자 진단을 위한 방법과 시스템 (systems and methods for non-invasive preimplantation genetic diagnosis) |
| WO2019084158A1 (en) | 2017-10-26 | 2019-05-02 | Ultima Genomics, Inc. | METHODS AND SYSTEMS FOR SEQUENCE CALL |
| EP3731959B1 (en) | 2017-12-29 | 2025-10-08 | Clear Labs, Inc. | Automated priming and library loading device |
| WO2019204720A1 (en) * | 2018-04-20 | 2019-10-24 | The Regents Of The University Of California | Nucleic acid sequencing methods and computer-readable media for practicing same |
| WO2020185790A1 (en) | 2019-03-10 | 2020-09-17 | Ultima Genomics, Inc. | Methods and systems for sequence calling |
| CN114303202A (zh) | 2019-06-21 | 2022-04-08 | 酷博尔外科器械有限公司 | 用于确定胚胎中遗传模式的系统和方法 |
| WO2021108532A2 (en) * | 2019-11-25 | 2021-06-03 | William Marsh Rice University | Linear dna assembly for nanopore sequencing |
| US20230249178A1 (en) | 2020-07-08 | 2023-08-10 | Roche Sequencing Solutions, Inc. | Split-pool synthesis apparatus and methods of performing split-pool synthesis |
| WO2022081741A1 (en) | 2020-10-15 | 2022-04-21 | Roche Sequencing Solutions, Inc. | Electrophoretic devices and methods for next-generation sequencing library preparation |
| CN114507708A (zh) * | 2020-11-16 | 2022-05-17 | 唐纳德·李 | 一种制备长分子测序dna的方法 |
| WO2022194764A1 (en) | 2021-03-15 | 2022-09-22 | F. Hoffmann-La Roche Ag | Targeted next-generation sequencing via anchored primer extension |
| WO2022200485A1 (en) | 2021-03-26 | 2022-09-29 | F. Hoffmann-La Roche Ag | Hybridization buffer formulations |
| EP4314337A1 (en) | 2021-04-01 | 2024-02-07 | F. Hoffmann-La Roche AG | Immune cell counting of sars-cov-2 patients based on immune repertoire sequencing |
| IL307398A (en) * | 2021-04-12 | 2023-12-01 | Univ Hong Kong Chinese | Base change analysis using electrical signals |
| WO2023023561A1 (en) * | 2021-08-17 | 2023-02-23 | Quantapore, Inc. | Multiplex binding assays with optical nanopore readout |
| US20250243536A1 (en) * | 2021-10-18 | 2025-07-31 | Belgian Volition Srl | Use of nanopore sequencing for determining the origin of circulating dna |
| EP4547839A1 (en) | 2022-06-30 | 2025-05-07 | Kapa Biosystems, Inc. | Controlling for tagmentation sequencing library insert size using archaeal histone-like proteins |
| CN114898802B (zh) * | 2022-07-14 | 2022-09-30 | 臻和(北京)生物科技有限公司 | 基于血浆游离dna甲基化测序数据的末端序列频率分布特征确定方法、评价方法及装置 |
| WO2024046992A1 (en) | 2022-09-02 | 2024-03-07 | F. Hoffmann-La Roche Ag | Improvements to next-generation target enrichment performance |
| JP2026519344A (ja) | 2023-04-13 | 2026-06-16 | ベンタナ メディカル システムズ， インコーポレイテッド | 固定固形腫瘍に対する増殖アッセイ |
| JP2026524816A (ja) | 2023-06-14 | 2026-07-24 | エフ． ホフマン－ラ ロシュ アーゲー | 加速された５－ホルミルシトシンのマーキングおよび核酸メチル化シーケンシングにおける使用 |
| WO2025193604A1 (en) | 2024-03-11 | 2025-09-18 | Ventana Medical Systems, Inc. | Non-enzymatic dissociation of ffpe tissue and generation of single cells with intact cell surface markers |
| WO2025210056A1 (en) | 2024-04-03 | 2025-10-09 | Roche Sequencing Solutions, Inc. | In vitro amplification of dna methylation patterns |
| WO2025247632A1 (en) | 2024-05-27 | 2025-12-04 | European Molecular Biology Laboratory | Preparation of cell-free fragmented nucleic acids for genetic analysis sequencing |
| WO2026082489A1 (en) | 2024-10-18 | 2026-04-23 | F. Hoffmann-La Roche Ag | Universal pcr to boost molecule recovery in cell free dna library preparation and target enrichment workflows |
| WO2026087220A1 (en) | 2024-10-22 | 2026-04-30 | F. Hoffmann-La Roche Ag | Preparation of dna libraries for next generation sequencing using y-adapters modified with phosphorothioate bonds |
| WO2026093331A1 (en) | 2024-10-28 | 2026-05-07 | F. Hoffmann-La Roche Ag | Hairpin adapter constructs and primers to generate next-generation sequencing library molecules |
| WO2026099278A1 (en) | 2024-11-08 | 2026-05-15 | F. Hoffmann-La Roche Ag | Normalizing and pooling of pcr-free sequencing libraries |
| WO2026151663A1 (en) | 2025-01-07 | 2026-07-16 | Kapa Biosystems, Inc. | Selective rna tagging methods of total nucleic samples for sequencing applications |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020197618A1 (en) | 2001-01-20 | 2002-12-26 | Sampson Jeffrey R. | Synthesis and amplification of unstructured nucleic acids for rapid sequencing |
| GB0504774D0 (en) * | 2005-03-08 | 2005-04-13 | Lingvitae As | Method |
| JP2008161056A (ja) | 2005-04-08 | 2008-07-17 | Hiroaki Mita | Ｄｎａ配列解析装置、ｄｎａ配列解析方法およびプログラム |
| US12054776B2 (en) | 2007-07-23 | 2024-08-06 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using massively parallel genomic sequencing |
| AU2009325069B2 (en) | 2008-12-11 | 2015-03-19 | Pacific Biosciences Of California, Inc. | Classification of nucleic acid templates |
| DE102008061772A1 (de) * | 2008-12-11 | 2010-06-17 | Febit Holding Gmbh | Verfahren zur Untersuchung von Nukleinsäure-Populationen |
| LT3241914T (lt) | 2009-11-05 | 2019-04-25 | The Chinese University Of Hong Kong | Vaisiaus genomo analizė iš motinos biologinio mėginio |
| CA2780016C (en) | 2009-11-06 | 2017-09-19 | The Chinese University Of Hong Kong | Size-based genomic analysis |
| US9121823B2 (en) * | 2010-02-19 | 2015-09-01 | The Trustees Of The University Of Pennsylvania | High-resolution analysis devices and related methods |
| KR20120045922A (ko) * | 2010-11-01 | 2012-05-09 | 엘지전자 주식회사 | 나노 포어를 포함하는 염기 서열 결정 장치 |
| KR102040307B1 (ko) | 2010-11-30 | 2019-11-27 | 더 차이니즈 유니버시티 오브 홍콩 | 암과 연관된 유전적 또는 분자적 이상들의 검출 |
| KR20140050067A (ko) * | 2011-07-25 | 2014-04-28 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 막횡단 포어를 사용한 이중 가닥 폴리뉴클레오티드 서열분석을 위한 헤어핀 루프 방법 |
| GB2485635B (en) * | 2011-07-26 | 2012-11-28 | Verinata Health Inc | Method for determining the presence or absence of different aneuploidies in a sample |
| US20130040827A1 (en) * | 2011-08-14 | 2013-02-14 | Stephen C. Macevicz | Method and compositions for detecting and sequencing nucleic acids |
| CA2861457A1 (en) | 2012-01-20 | 2013-07-25 | Genia Technologies, Inc. | Nanopore based molecular detection and sequencing |
| GB2559073A (en) * | 2012-06-08 | 2018-07-25 | Pacific Biosciences California Inc | Modified base detection with nanopore sequencing |
| JP2015525077A (ja) * | 2012-06-15 | 2015-09-03 | ジェニア・テクノロジーズ・インコーポレイテッド | チップの構成および高精度な核酸配列決定 |
| US11261494B2 (en) * | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
| GB201215449D0 (en) | 2012-08-30 | 2012-10-17 | Zoragen Biotechnologies Llp | Method of detecting chromosonal abnormalities |
| HUE053822T2 (hu) | 2012-09-20 | 2021-07-28 | Univ Hong Kong Chinese | Nem invazív módszer daganat metilom meghatározása plazmából |
| IL274464B2 (en) * | 2013-12-11 | 2023-08-01 | Accuragen Holdings Ltd | Preparations and methods for the detection of rare sequence variants |
| WO2016077313A1 (en) * | 2014-11-11 | 2016-05-19 | Bgi Shenzhen | Multi-pass sequencing |
| AU2016406443A1 (en) | 2016-05-10 | 2018-11-15 | Nec Corporation | Demand and supply adjustment system, control apparatus, control method, and program |
-
2016
- 2016-08-12 US US15/235,630 patent/US11319586B2/en active Active
- 2016-08-12 TW TW105125873A patent/TWI728994B/zh active
- 2016-08-12 CA CA2995422A patent/CA2995422A1/en active Pending
- 2016-08-12 WO PCT/CN2016/094802 patent/WO2017025059A1/en not_active Ceased
- 2016-08-12 MY MYPI2018000139A patent/MY188348A/en unknown
- 2016-08-12 CN CN202211147693.8A patent/CN115433769A/zh active Pending
- 2016-08-12 TW TW110115619A patent/TWI793586B/zh active
- 2016-08-12 EP EP16834683.1A patent/EP3334843A4/en active Pending
- 2016-08-12 IL IL285795A patent/IL285795B/en unknown
- 2016-08-12 HK HK18108082.2A patent/HK1248286A1/zh unknown
- 2016-08-12 AU AU2016305103A patent/AU2016305103C1/en active Active
- 2016-08-12 JP JP2018506601A patent/JP6867045B2/ja active Active
- 2016-08-12 CN CN201680046621.0A patent/CN107849607B/zh active Active
-
2018
- 2018-01-22 IL IL257074A patent/IL257074B/en unknown
- 2018-02-12 SA SA518390907A patent/SA518390907B1/ar unknown
-
2020
- 2020-03-26 AU AU2020202153A patent/AU2020202153B2/en active Active
-
2021
- 2021-03-31 JP JP2021060027A patent/JP7506408B2/ja active Active
-
2022
- 2022-03-18 US US17/698,574 patent/US20220205038A1/en active Pending
- 2022-06-22 IL IL294192A patent/IL294192B2/en unknown
-
2023
- 2023-04-27 AU AU2023202572A patent/AU2023202572B2/en active Active
-
2024
- 2024-06-07 JP JP2024092950A patent/JP7810455B2/ja active Active
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