TWI728994B - 血漿dna之單分子定序 - Google Patents

血漿dna之單分子定序 Download PDF

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TWI728994B
TWI728994B TW105125873A TW105125873A TWI728994B TW I728994 B TWI728994 B TW I728994B TW 105125873 A TW105125873 A TW 105125873A TW 105125873 A TW105125873 A TW 105125873A TW I728994 B TWI728994 B TW I728994B
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dna fragments
plasma
sequence
dna
serum
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TW105125873A
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TW201718874A (zh
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煜明 盧
慧君 趙
淑恒 鄭
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香港中文大學
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    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60Detection means characterised by use of a special device
    • C12Q2565/631Detection means characterised by use of a special device being a biochannel or pore

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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TW105125873A 2015-08-12 2016-08-12 血漿dna之單分子定序 TWI728994B (zh)

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US201562204396P 2015-08-12 2015-08-12
US62/204,396 2015-08-12

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TWI728994B true TWI728994B (zh) 2021-06-01

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US (2) US11319586B2 (enExample)
EP (1) EP3334843A4 (enExample)
JP (3) JP6867045B2 (enExample)
CN (2) CN115433769A (enExample)
AU (3) AU2016305103C1 (enExample)
CA (1) CA2995422A1 (enExample)
HK (1) HK1248286A1 (enExample)
IL (3) IL285795B (enExample)
MY (1) MY188348A (enExample)
SA (1) SA518390907B1 (enExample)
TW (2) TWI793586B (enExample)
WO (1) WO2017025059A1 (enExample)

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CN114507708A (zh) * 2020-11-16 2022-05-17 唐纳德·李 一种制备长分子测序dna的方法
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WO2023023561A1 (en) * 2021-08-17 2023-02-23 Quantapore, Inc. Multiplex binding assays with optical nanopore readout
WO2023067597A1 (en) * 2021-10-18 2023-04-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Use of nanopore sequencing for determining the origin of circulating dna
US20250368983A1 (en) 2022-06-30 2025-12-04 Kapa Biosystems, Inc. Controlling for tagmentation sequencing library insert size using archaeal histone-like proteins
CN114898802B (zh) * 2022-07-14 2022-09-30 臻和(北京)生物科技有限公司 基于血浆游离dna甲基化测序数据的末端序列频率分布特征确定方法、评价方法及装置
JP2025528488A (ja) 2022-09-02 2025-08-28 エフ. ホフマン-ラ ロシュ アーゲー 次世代標的濃縮性能の改善
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JP2018531583A (ja) 2018-11-01
JP2024113130A (ja) 2024-08-21
EP3334843A4 (en) 2019-01-02
TW202130815A (zh) 2021-08-16
JP7506408B2 (ja) 2024-06-26
AU2023202572B2 (en) 2025-04-10
CN107849607A (zh) 2018-03-27
CN107849607B (zh) 2022-10-11
AU2016305103A1 (en) 2018-03-22
AU2023202572A1 (en) 2023-05-18
IL285795B (en) 2022-07-01
IL294192B2 (en) 2023-08-01
AU2020202153A1 (en) 2020-04-16
JP2021118691A (ja) 2021-08-12
HK1245850A1 (zh) 2018-08-31
AU2016305103C1 (en) 2020-06-04
TW201718874A (zh) 2017-06-01
TWI793586B (zh) 2023-02-21
AU2016305103B2 (en) 2020-01-02
WO2017025059A1 (en) 2017-02-16
AU2020202153B2 (en) 2023-02-02
IL285795A (en) 2021-09-30
MY188348A (en) 2021-12-02
IL257074A (en) 2018-03-29
JP6867045B2 (ja) 2021-04-28
US11319586B2 (en) 2022-05-03
US20220205038A1 (en) 2022-06-30
HK1248286A1 (zh) 2018-10-12
IL257074B (en) 2021-09-30
EP3334843A1 (en) 2018-06-20
US20170044606A1 (en) 2017-02-16
SA518390907B1 (ar) 2021-09-08
IL294192B1 (en) 2023-04-01
CN115433769A (zh) 2022-12-06
IL294192A (en) 2022-08-01
CA2995422A1 (en) 2017-02-16

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