GB2485635B - Method for determining the presence or absence of different aneuploidies in a sample - Google Patents
Method for determining the presence or absence of different aneuploidies in a sampleInfo
- Publication number
- GB2485635B GB2485635B GB1114713.9A GB201114713A GB2485635B GB 2485635 B GB2485635 B GB 2485635B GB 201114713 A GB201114713 A GB 201114713A GB 2485635 B GB2485635 B GB 2485635B
- Authority
- GB
- United Kingdom
- Prior art keywords
- absence
- sample
- determining
- different aneuploidies
- aneuploidies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000036878 aneuploidy Diseases 0.000 title 1
- 231100001075 aneuploidy Toxicity 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B45/00—ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Data Mining & Analysis (AREA)
- Bioethics (AREA)
- Databases & Information Systems (AREA)
- Physiology (AREA)
- Pathology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Artificial Intelligence (AREA)
- Animal Behavior & Ethology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/045412 WO2013015793A1 (en) | 2011-07-26 | 2011-07-26 | Method for determining the presence or absence of different aneuploidies in a sample |
Publications (3)
Publication Number | Publication Date |
---|---|
GB201114713D0 GB201114713D0 (en) | 2011-10-12 |
GB2485635A GB2485635A (en) | 2012-05-23 |
GB2485635B true GB2485635B (en) | 2012-11-28 |
Family
ID=44838718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1114713.9A Active GB2485635B (en) | 2011-07-26 | 2011-07-26 | Method for determining the presence or absence of different aneuploidies in a sample |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2563937A1 (en) |
JP (1) | JP6161607B2 (en) |
KR (1) | KR101974492B1 (en) |
CN (1) | CN103003447B (en) |
AU (1) | AU2011373694A1 (en) |
CA (1) | CA2840418C (en) |
GB (1) | GB2485635B (en) |
HK (1) | HK1174063A1 (en) |
WO (1) | WO2013015793A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9657342B2 (en) | 2010-01-19 | 2017-05-23 | Verinata Health, Inc. | Sequencing methods for prenatal diagnoses |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100112590A1 (en) | 2007-07-23 | 2010-05-06 | The Chinese University Of Hong Kong | Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment |
CA2786565C (en) | 2010-01-19 | 2017-04-25 | Verinata Health, Inc. | Partition defined detection methods |
US10388403B2 (en) | 2010-01-19 | 2019-08-20 | Verinata Health, Inc. | Analyzing copy number variation in the detection of cancer |
US9323888B2 (en) | 2010-01-19 | 2016-04-26 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US20120100548A1 (en) | 2010-10-26 | 2012-04-26 | Verinata Health, Inc. | Method for determining copy number variations |
US10662474B2 (en) | 2010-01-19 | 2020-05-26 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing |
WO2011090556A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Methods for determining fraction of fetal nucleic acid in maternal samples |
US9260745B2 (en) | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
PL3456844T3 (en) | 2011-04-12 | 2020-11-16 | Verinata Health, Inc. | Resolving genome fractions using polymorphism counts |
US9411937B2 (en) * | 2011-04-15 | 2016-08-09 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US11261494B2 (en) * | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
AU2019200162B2 (en) * | 2012-07-20 | 2021-10-07 | Verinata Health, Inc. | Detecting and classifying copy number variation |
AU2013204615A1 (en) * | 2012-07-20 | 2014-02-06 | Verinata Health, Inc. | Detecting and classifying copy number variation in a fetal genome |
AU2013204536A1 (en) * | 2012-07-20 | 2014-02-06 | Verinata Health, Inc. | Detecting and classifying copy number variation in a cancer genome |
CN104736725A (en) | 2012-08-13 | 2015-06-24 | 加利福尼亚大学董事会 | Methods and systems for detecting biological components |
GB201215449D0 (en) * | 2012-08-30 | 2012-10-17 | Zoragen Biotechnologies Llp | Method of detecting chromosonal abnormalities |
JP6426162B2 (en) * | 2013-06-13 | 2018-11-21 | アリオサ ダイアグノスティックス インコーポレイテッドAriosa Diagnostics,Inc. | Method of noninvasively calculating the risk of fetal sex chromosome aneuploidy |
AU2014281635B2 (en) * | 2013-06-17 | 2020-05-28 | Verinata Health, Inc. | Method for determining copy number variations in sex chromosomes |
CN104520437B (en) * | 2013-07-17 | 2016-09-14 | 深圳华大基因股份有限公司 | A kind of chromosomal aneuploidy detection method and device |
ES2968644T3 (en) * | 2013-10-04 | 2024-05-13 | Sequenom Inc | Methods and procedures for the non-invasive evaluation of genetic variations |
CA2928185C (en) * | 2013-10-21 | 2024-01-30 | Verinata Health, Inc. | Method for improving the sensitivity of detection in determining copy number variations |
CN105765076B (en) * | 2013-12-17 | 2019-07-19 | 深圳华大基因股份有限公司 | A kind of chromosomal aneuploidy detection method and device |
US10318704B2 (en) | 2014-05-30 | 2019-06-11 | Verinata Health, Inc. | Detecting fetal sub-chromosomal aneuploidies |
US10697007B2 (en) | 2014-06-27 | 2020-06-30 | The Regents Of The University Of California | PCR-activated sorting (PAS) |
WO2016045106A1 (en) * | 2014-09-26 | 2016-03-31 | 深圳华大基因股份有限公司 | Cnv analysis method for chromosomes of single-cell and detection device |
EP3209419A4 (en) | 2014-10-22 | 2018-10-03 | The Regents of The University of California | High definition microdroplet printer |
EP3567120B1 (en) * | 2014-12-12 | 2020-08-19 | Verinata Health, Inc. | Using cell-free dna fragment size to determine copy number variations |
ES2923602T3 (en) * | 2014-12-31 | 2022-09-28 | Guardant Health Inc | Detection and treatment of diseases showing cellular heterogeneity of disease and systems and methods for communicating test results |
US10319463B2 (en) * | 2015-01-23 | 2019-06-11 | The Chinese University Of Hong Kong | Combined size- and count-based analysis of maternal plasma for detection of fetal subchromosomal aberrations |
EP4112744A1 (en) | 2015-02-04 | 2023-01-04 | The Regents of the University of California | Sequencing of nucleic acids via barcoding in discrete entities |
WO2016127944A1 (en) | 2015-02-10 | 2016-08-18 | The Chinese University Of Hong Kong | Detecting mutations for cancer screening and fetal analysis |
CN104745718B (en) * | 2015-04-23 | 2018-02-16 | 北京中仪康卫医疗器械有限公司 | A kind of method for detecting human embryos microdeletion and micro- repetition |
US10844428B2 (en) * | 2015-04-28 | 2020-11-24 | Illumina, Inc. | Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS) |
WO2017031125A1 (en) * | 2015-08-17 | 2017-02-23 | The Regents Of The University Of California | Microdroplet-based multiple displacement amplification (mda) methods and related compositions |
WO2017044609A1 (en) | 2015-09-08 | 2017-03-16 | Cold Spring Harbor Laboratory | Genetic copy number determination using high throughput multiplex sequencing of smashed nucleotides |
WO2017083828A1 (en) * | 2015-11-12 | 2017-05-18 | Samuel Williams | Rapid sequencing of short dna fragments using nanopore technology |
CN108475301A (en) * | 2015-12-04 | 2018-08-31 | 绿十字基因组公司 | The method of copy number variation in sample for determining the mixture comprising nucleic acid |
US10095831B2 (en) | 2016-02-03 | 2018-10-09 | Verinata Health, Inc. | Using cell-free DNA fragment size to determine copy number variations |
WO2018009723A1 (en) * | 2016-07-06 | 2018-01-11 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
CN110088290A (en) | 2016-08-10 | 2019-08-02 | 加利福尼亚大学董事会 | Multiple displacement amplification and PCR are combined in lotion droplet |
TWI603082B (en) * | 2016-09-30 | 2017-10-21 | 有勁生物科技股份有限公司 | Non-invasive fetal sex abnormality detecting system and method thereof and non-invasive fetal sex determination system and method thereof |
CN110462053A (en) | 2016-12-21 | 2019-11-15 | 加利福尼亚大学董事会 | Unicellular gene order-checking is carried out using the drop based on hydrogel |
EP3574108A4 (en) | 2017-01-25 | 2020-12-23 | The Chinese University Of Hong Kong | Diagnostic applications using nucleic acid fragments |
US11342047B2 (en) * | 2017-04-21 | 2022-05-24 | Illumina, Inc. | Using cell-free DNA fragment size to detect tumor-associated variant |
JP2018183095A (en) * | 2017-04-26 | 2018-11-22 | 株式会社エンプラス | Method for isolating fetus-derived hemopoietic precursor cell, and method for testing possibility of chromosomal aberration of fetus |
US10501739B2 (en) | 2017-10-18 | 2019-12-10 | Mission Bio, Inc. | Method, systems and apparatus for single cell analysis |
SG11202110655UA (en) * | 2019-03-28 | 2021-10-28 | Phase Genomics Inc | Systems and methods for karyotyping by sequencing |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2479080A (en) * | 2010-01-19 | 2011-09-28 | Artemis Health Inc | Sequencing methods and compositions for prenatal diagnoses |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007100911A2 (en) * | 2006-02-28 | 2007-09-07 | University Of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
US20080050739A1 (en) * | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
PL2557520T3 (en) * | 2007-07-23 | 2021-10-11 | The Chinese University Of Hong Kong | Determining a nucleic acid sequence imbalance |
US20100112590A1 (en) * | 2007-07-23 | 2010-05-06 | The Chinese University Of Hong Kong | Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment |
CA2701726A1 (en) | 2007-10-04 | 2009-04-09 | Halcyon Molecular | Sequencing nucleic acid polymers with electron microscopy |
PT2334812T (en) * | 2008-09-20 | 2017-03-29 | Univ Leland Stanford Junior | Noninvasive diagnosis of fetal aneuploidy by sequencing |
EP2494065B1 (en) * | 2009-10-26 | 2015-12-23 | Lifecodexx AG | Means and methods for non-invasive diagnosis of chromosomal aneuploidy |
US10662474B2 (en) * | 2010-01-19 | 2020-05-26 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing |
CA2786565C (en) * | 2010-01-19 | 2017-04-25 | Verinata Health, Inc. | Partition defined detection methods |
-
2011
- 2011-07-26 WO PCT/US2011/045412 patent/WO2013015793A1/en active Application Filing
- 2011-07-26 AU AU2011373694A patent/AU2011373694A1/en not_active Abandoned
- 2011-07-26 JP JP2014522796A patent/JP6161607B2/en active Active
- 2011-07-26 KR KR1020147002820A patent/KR101974492B1/en active IP Right Grant
- 2011-07-26 CA CA2840418A patent/CA2840418C/en active Active
- 2011-07-26 CN CN201180022958.5A patent/CN103003447B/en active Active
- 2011-07-26 GB GB1114713.9A patent/GB2485635B/en active Active
- 2011-07-26 EP EP11744148A patent/EP2563937A1/en not_active Withdrawn
-
2012
- 2012-10-26 HK HK12110738.2A patent/HK1174063A1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2479080A (en) * | 2010-01-19 | 2011-09-28 | Artemis Health Inc | Sequencing methods and compositions for prenatal diagnoses |
GB2479476A (en) * | 2010-01-19 | 2011-10-12 | Artemis Health Inc | Simultaneous determination of aneuploidy and fetal fraction |
GB2479471A (en) * | 2010-01-19 | 2011-10-12 | Artemis Health Inc | Method for determining copy number variations |
Non-Patent Citations (3)
Title |
---|
Clinical Chemistry 57 (2011) Sehnert et al 'Optimal detection of fetal chromosomal abnormalities by massively parallel DNA sequencing of cell-free fetal DNA from maternal blood' 1042-1049 * |
Clinical Chemistry 57 (2011) Sehnert et al 'Optimal detection of fetal chromosomal abnormalities by massively parallel DNA sequencing of cell-free fetal DNA from maternal blood.' 1042-1049 * |
PLoS One 5 (2010) Fan and Quake 'Sensitivity of Noninvasive Prenatal Detection of Fetal Aneuploidy from Maternal Plasma Using Shotgun Sequencing Is Limited Only by Counting Statistics' e10439 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9657342B2 (en) | 2010-01-19 | 2017-05-23 | Verinata Health, Inc. | Sequencing methods for prenatal diagnoses |
Also Published As
Publication number | Publication date |
---|---|
GB201114713D0 (en) | 2011-10-12 |
KR101974492B1 (en) | 2019-05-02 |
KR20140050032A (en) | 2014-04-28 |
JP6161607B2 (en) | 2017-07-12 |
CN103003447B (en) | 2020-08-25 |
CA2840418A1 (en) | 2013-01-31 |
HK1174063A1 (en) | 2013-05-31 |
EP2563937A1 (en) | 2013-03-06 |
CN103003447A (en) | 2013-03-27 |
AU2011373694A1 (en) | 2013-05-02 |
CA2840418C (en) | 2019-10-29 |
GB2485635A (en) | 2012-05-23 |
WO2013015793A1 (en) | 2013-01-31 |
JP2014521334A (en) | 2014-08-28 |
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