JP2018529779A - 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 - Google Patents
活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 Download PDFInfo
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- JP2018529779A JP2018529779A JP2018536704A JP2018536704A JP2018529779A JP 2018529779 A JP2018529779 A JP 2018529779A JP 2018536704 A JP2018536704 A JP 2018536704A JP 2018536704 A JP2018536704 A JP 2018536704A JP 2018529779 A JP2018529779 A JP 2018529779A
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- nitro
- octadeca
- acid
- enoic acid
- disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021139287A JP2021183640A (ja) | 2015-10-02 | 2021-08-27 | 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562236702P | 2015-10-02 | 2015-10-02 | |
| US62/236,702 | 2015-10-02 | ||
| PCT/US2016/055206 WO2017059451A1 (en) | 2015-10-02 | 2016-10-03 | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021139287A Division JP2021183640A (ja) | 2015-10-02 | 2021-08-27 | 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018529779A true JP2018529779A (ja) | 2018-10-11 |
| JP2018529779A5 JP2018529779A5 (enExample) | 2019-11-14 |
Family
ID=58428002
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536704A Withdrawn JP2018529779A (ja) | 2015-10-02 | 2016-10-03 | 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 |
| JP2021139287A Pending JP2021183640A (ja) | 2015-10-02 | 2021-08-27 | 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021139287A Pending JP2021183640A (ja) | 2015-10-02 | 2021-08-27 | 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10537541B2 (enExample) |
| EP (1) | EP3355879A4 (enExample) |
| JP (2) | JP2018529779A (enExample) |
| KR (1) | KR20180098222A (enExample) |
| CN (2) | CN113440506A (enExample) |
| AU (2) | AU2016331314A1 (enExample) |
| BR (1) | BR112018006687A2 (enExample) |
| CA (1) | CA3000842A1 (enExample) |
| CL (1) | CL2018000835A1 (enExample) |
| CO (1) | CO2018004576A2 (enExample) |
| CR (1) | CR20180246A (enExample) |
| EA (1) | EA201890859A1 (enExample) |
| HK (1) | HK1259031A1 (enExample) |
| IL (2) | IL258476B2 (enExample) |
| MX (1) | MX2018004043A (enExample) |
| SG (1) | SG10201913953UA (enExample) |
| WO (1) | WO2017059451A1 (enExample) |
Families Citing this family (12)
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|---|---|---|---|---|
| WO2009134383A2 (en) * | 2008-05-01 | 2009-11-05 | Complexa Inc. | Vinyl substituted fatty acids |
| US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| BR112018000254A2 (pt) | 2015-07-07 | 2018-09-04 | H Lundbeck As | inibidores de pde9 com cadeia principal de imidazotriazinona e cadeia principal de imidazopirazinona para o tratamento de doenças periféricas |
| IL258476B2 (en) * | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| EP3801526B1 (en) | 2018-05-25 | 2023-12-27 | Imara Inc. | Monohydrate and crystalline forms of 6-[(3s,4s)-4-methyl-1- (pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl- 7h-imid azo [1,5- a] pyrazin-8-one |
| CN112996512B (zh) | 2018-08-31 | 2025-01-03 | 卡都瑞恩医药公司 | 用于治疗镰状细胞病的pde9抑制剂 |
| CN111229117B (zh) * | 2018-11-29 | 2022-01-04 | 中国石油化工股份有限公司 | 含脂肪酸型表面活性剂的混合体系及其制备方法 |
| CN111229120B (zh) * | 2018-11-29 | 2022-01-07 | 中国石油化工股份有限公司 | 含脂肪酸型表面活性剂的混合体系及其制备方法 |
| FR3092968B1 (fr) * | 2019-02-22 | 2021-05-21 | Microphyt | Complement alimentaire |
| CN110157792A (zh) * | 2019-04-22 | 2019-08-23 | 中山大学孙逸仙纪念医院 | 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用 |
| WO2021242758A1 (en) * | 2020-05-26 | 2021-12-02 | Imara Inc. | Improved nitro-fatty acid oral dose regimens |
| WO2023014748A1 (en) * | 2021-08-03 | 2023-02-09 | Imara Inc. | Nitrated fatty acids for the treatment of sickle cell disorders |
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2016
- 2016-10-03 IL IL258476A patent/IL258476B2/en unknown
- 2016-10-03 EP EP16852846.1A patent/EP3355879A4/en not_active Withdrawn
- 2016-10-03 EA EA201890859A patent/EA201890859A1/ru unknown
- 2016-10-03 HK HK19101519.9A patent/HK1259031A1/zh unknown
- 2016-10-03 JP JP2018536704A patent/JP2018529779A/ja not_active Withdrawn
- 2016-10-03 MX MX2018004043A patent/MX2018004043A/es unknown
- 2016-10-03 CN CN202110744035.6A patent/CN113440506A/zh active Pending
- 2016-10-03 CN CN201680070797.XA patent/CN108430466A/zh active Pending
- 2016-10-03 BR BR112018006687A patent/BR112018006687A2/pt not_active Application Discontinuation
- 2016-10-03 CR CR20180246A patent/CR20180246A/es unknown
- 2016-10-03 US US15/283,887 patent/US10537541B2/en not_active Expired - Fee Related
- 2016-10-03 IL IL297844A patent/IL297844A/en unknown
- 2016-10-03 WO PCT/US2016/055206 patent/WO2017059451A1/en not_active Ceased
- 2016-10-03 AU AU2016331314A patent/AU2016331314A1/en not_active Abandoned
- 2016-10-03 SG SG10201913953UA patent/SG10201913953UA/en unknown
- 2016-10-03 CA CA3000842A patent/CA3000842A1/en not_active Abandoned
- 2016-10-03 KR KR1020187012337A patent/KR20180098222A/ko not_active Ceased
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2018
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- 2018-04-27 CO CONC2018/0004576A patent/CO2018004576A2/es unknown
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2019
- 2019-10-18 US US16/657,028 patent/US20200046669A1/en not_active Abandoned
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2021
- 2021-03-19 US US17/207,380 patent/US20220000824A1/en not_active Abandoned
- 2021-07-14 AU AU2021205027A patent/AU2021205027A1/en not_active Abandoned
- 2021-08-27 JP JP2021139287A patent/JP2021183640A/ja active Pending
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| AU2021205027A1 (en) | 2021-08-12 |
| CN113440506A (zh) | 2021-09-28 |
| KR20180098222A (ko) | 2018-09-03 |
| US10537541B2 (en) | 2020-01-21 |
| SG10201913953UA (en) | 2020-03-30 |
| WO2017059451A1 (en) | 2017-04-06 |
| CL2018000835A1 (es) | 2018-09-14 |
| IL258476B2 (en) | 2023-04-01 |
| US20170095437A1 (en) | 2017-04-06 |
| US20220000824A1 (en) | 2022-01-06 |
| EA201890859A1 (ru) | 2018-11-30 |
| CO2018004576A2 (es) | 2018-07-19 |
| IL258476A (en) | 2018-06-28 |
| CN108430466A (zh) | 2018-08-21 |
| IL258476B (en) | 2022-12-01 |
| MX2018004043A (es) | 2018-11-09 |
| HK1259031A1 (zh) | 2019-11-22 |
| JP2021183640A (ja) | 2021-12-02 |
| EP3355879A1 (en) | 2018-08-08 |
| BR112018006687A2 (pt) | 2018-10-09 |
| AU2016331314A1 (en) | 2018-05-17 |
| CA3000842A1 (en) | 2017-04-06 |
| US20200046669A1 (en) | 2020-02-13 |
| EP3355879A4 (en) | 2019-05-22 |
| CR20180246A (es) | 2018-11-22 |
| IL297844A (en) | 2023-01-01 |
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