CO2018004576A2 - Composición farmacéutica que comprende ácidos grasos activados - Google Patents

Composición farmacéutica que comprende ácidos grasos activados

Info

Publication number
CO2018004576A2
CO2018004576A2 CONC2018/0004576A CO2018004576A CO2018004576A2 CO 2018004576 A2 CO2018004576 A2 CO 2018004576A2 CO 2018004576 A CO2018004576 A CO 2018004576A CO 2018004576 A2 CO2018004576 A2 CO 2018004576A2
Authority
CO
Colombia
Prior art keywords
fatty acids
pharmaceutical composition
activated fatty
nitro
methods
Prior art date
Application number
CONC2018/0004576A
Other languages
English (en)
Inventor
Diane Jorkasky
Original Assignee
Complexa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Complexa Inc filed Critical Complexa Inc
Publication of CO2018004576A2 publication Critical patent/CO2018004576A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Varias modalidades de esta invención se dirigen a composiciones y métodos farmacéuticos para tratar enfermedades, incluyendo glomeruloesclerosis segmentaria focal o hipertensión arterial pulmonar. Las composiciones de tales modalidades incluyen ácidos grasos activados tales como ácidos grasos sustituidos con alquilo, ácidos grasos ceto y ácidos grasos nitro. Los métodos de varias modalidades incluyen administrar una cantidad efectiva de ácido 10-nitro-9(E)-octadec-9-enoico para tratar tales enfermedades.
CONC2018/0004576A 2015-10-02 2018-04-27 Composición farmacéutica que comprende ácidos grasos activados CO2018004576A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562236702P 2015-10-02 2015-10-02
PCT/US2016/055206 WO2017059451A1 (en) 2015-10-02 2016-10-03 Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids

Publications (1)

Publication Number Publication Date
CO2018004576A2 true CO2018004576A2 (es) 2018-07-19

Family

ID=58428002

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0004576A CO2018004576A2 (es) 2015-10-02 2018-04-27 Composición farmacéutica que comprende ácidos grasos activados

Country Status (17)

Country Link
US (3) US10537541B2 (es)
EP (1) EP3355879A4 (es)
JP (2) JP2018529779A (es)
KR (1) KR20180098222A (es)
CN (2) CN108430466A (es)
AU (2) AU2016331314A1 (es)
BR (1) BR112018006687A2 (es)
CA (1) CA3000842A1 (es)
CL (1) CL2018000835A1 (es)
CO (1) CO2018004576A2 (es)
CR (1) CR20180246A (es)
EA (1) EA201890859A1 (es)
HK (1) HK1259031A1 (es)
IL (2) IL258476B2 (es)
MX (1) MX2018004043A (es)
SG (1) SG10201913953UA (es)
WO (1) WO2017059451A1 (es)

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CN117843645A (zh) 2018-05-25 2024-04-09 伊马拉公司 一种pde9抑制剂的一水合物和结晶形态
CN111229120B (zh) * 2018-11-29 2022-01-07 中国石油化工股份有限公司 含脂肪酸型表面活性剂的混合体系及其制备方法
CN111229117B (zh) * 2018-11-29 2022-01-04 中国石油化工股份有限公司 含脂肪酸型表面活性剂的混合体系及其制备方法
FR3092968B1 (fr) * 2019-02-22 2021-05-21 Microphyt Complement alimentaire
CN110157792A (zh) * 2019-04-22 2019-08-23 中山大学孙逸仙纪念医院 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用
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WO2023014748A1 (en) * 2021-08-03 2023-02-09 Imara Inc. Nitrated fatty acids for the treatment of sickle cell disorders

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Also Published As

Publication number Publication date
IL297844A (en) 2023-01-01
EP3355879A1 (en) 2018-08-08
AU2016331314A1 (en) 2018-05-17
AU2021205027A1 (en) 2021-08-12
WO2017059451A1 (en) 2017-04-06
EA201890859A1 (ru) 2018-11-30
JP2018529779A (ja) 2018-10-11
CN108430466A (zh) 2018-08-21
US10537541B2 (en) 2020-01-21
US20200046669A1 (en) 2020-02-13
CA3000842A1 (en) 2017-04-06
IL258476B2 (en) 2023-04-01
CL2018000835A1 (es) 2018-09-14
HK1259031A1 (zh) 2019-11-22
JP2021183640A (ja) 2021-12-02
BR112018006687A2 (pt) 2018-10-09
US20170095437A1 (en) 2017-04-06
KR20180098222A (ko) 2018-09-03
CR20180246A (es) 2018-11-22
IL258476A (en) 2018-06-28
SG10201913953UA (en) 2020-03-30
IL258476B (en) 2022-12-01
EP3355879A4 (en) 2019-05-22
US20220000824A1 (en) 2022-01-06
CN113440506A (zh) 2021-09-28
MX2018004043A (es) 2018-11-09

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