JP2018524336A5 - - Google Patents
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- Publication number
- JP2018524336A5 JP2018524336A5 JP2017567321A JP2017567321A JP2018524336A5 JP 2018524336 A5 JP2018524336 A5 JP 2018524336A5 JP 2017567321 A JP2017567321 A JP 2017567321A JP 2017567321 A JP2017567321 A JP 2017567321A JP 2018524336 A5 JP2018524336 A5 JP 2018524336A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- haloalkyl
- group
- halogen
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229910052736 halogen Inorganic materials 0.000 claims description 48
- 150000002367 halogens Chemical class 0.000 claims description 48
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 44
- 125000000217 alkyl group Chemical group 0.000 claims description 35
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims description 31
- 125000001424 substituent group Chemical group 0.000 claims description 31
- 150000001875 compounds Chemical class 0.000 claims description 25
- 229910052739 hydrogen Inorganic materials 0.000 claims description 24
- 239000001257 hydrogen Substances 0.000 claims description 24
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims description 21
- -1 C 1 -C 6 alkyl Chemical group 0.000 claims description 21
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 18
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 18
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 16
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 16
- 125000003545 alkoxy group Chemical group 0.000 claims description 16
- 125000004122 cyclic group Chemical group 0.000 claims description 16
- 125000004770 (C1-C4) haloalkylsulfanyl group Chemical group 0.000 claims description 14
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 14
- 229910052717 sulfur Inorganic materials 0.000 claims description 14
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 13
- 125000004740 (C1-C6) haloalkylsulfanyl group Chemical group 0.000 claims description 12
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims description 12
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims description 12
- 229910052760 oxygen Inorganic materials 0.000 claims description 12
- 125000004771 (C1-C4) haloalkylsulfinyl group Chemical group 0.000 claims description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 10
- 125000001188 haloalkyl group Chemical group 0.000 claims description 10
- 239000001301 oxygen Substances 0.000 claims description 10
- 239000011593 sulfur Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 229910052757 nitrogen Inorganic materials 0.000 claims description 9
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 9
- 125000004768 (C1-C4) alkylsulfinyl group Chemical group 0.000 claims description 8
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 claims description 8
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims description 8
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 8
- 241000607479 Yersinia pestis Species 0.000 claims description 8
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 8
- 150000002431 hydrogen Chemical class 0.000 claims description 8
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims description 7
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims description 6
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims description 6
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims description 6
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims description 6
- 229920006395 saturated elastomer Polymers 0.000 claims description 6
- 125000003118 aryl group Chemical group 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 5
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims description 4
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 claims description 4
- 150000001204 N-oxides Chemical class 0.000 claims description 4
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical group C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims description 4
- 125000000304 alkynyl group Chemical group 0.000 claims description 4
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims description 4
- 125000005842 heteroatom Chemical group 0.000 claims description 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 4
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims description 4
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 125000004434 sulfur atom Chemical group 0.000 claims description 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims description 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 150000001412 amines Chemical group 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims description 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 2
- 239000012752 auxiliary agent Substances 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 description 7
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 description 7
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 description 6
- 125000006310 cycloalkyl amino group Chemical group 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 description 2
- 125000000232 haloalkynyl group Chemical group 0.000 description 2
- 241000256186 Anopheles <genus> Species 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 description 1
- 230000001548 androgenic effect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15174760.7 | 2015-07-01 | ||
| EP15174760 | 2015-07-01 | ||
| EP15184065.9 | 2015-09-07 | ||
| EP15184065 | 2015-09-07 | ||
| PCT/EP2016/064784 WO2017001314A1 (en) | 2015-07-01 | 2016-06-27 | Pesticidally active polycyclic derivatives with sulfur containing substituents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018524336A JP2018524336A (ja) | 2018-08-30 |
| JP2018524336A5 true JP2018524336A5 (enExample) | 2019-08-08 |
Family
ID=56203412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017567321A Ceased JP2018524336A (ja) | 2015-07-01 | 2016-06-27 | 硫黄含有置換基を有する有害生物防除に活性な多環式誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10745396B2 (enExample) |
| EP (1) | EP3317276B1 (enExample) |
| JP (1) | JP2018524336A (enExample) |
| CN (1) | CN107735396B (enExample) |
| BR (1) | BR112017028600A2 (enExample) |
| WO (1) | WO2017001314A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112018010347A2 (pt) * | 2015-11-23 | 2018-12-04 | Syngenta Participations Ag | derivados heterocíclicos ativos em termos pesticidas com substituintes contendo enxofre e ciclopropila |
| BR112019008492B1 (pt) * | 2016-10-27 | 2024-01-30 | Syngenta Participations Ag | Compostos derivados heterocíclicos ativos em termos pesticidas com substituintes contendo enxofre e hidroxilamina, composição pesticida, método para controle de pragas e método para a proteção de material de propagação de plantas do ataque por pragas |
| DE112018001170T5 (de) * | 2017-03-06 | 2019-11-21 | Sumitomo Chemical Company, Limited | Verfahren zur Herstellung einer Triazolverbindung |
| KR102694625B1 (ko) | 2017-05-10 | 2024-08-12 | 바스프 에스이 | 바이시클릭 화합물 |
| EP3453706A1 (en) | 2017-09-08 | 2019-03-13 | Basf Se | Pesticidal imidazole compounds |
| AU2018332263B2 (en) * | 2017-09-18 | 2023-02-09 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| US11019821B2 (en) | 2018-02-21 | 2021-06-01 | Bayer Aktiengesellschaft | Fused bicyclic heterocycle derivatives as pesticides |
| US11414432B2 (en) | 2018-03-12 | 2022-08-16 | Bayer Aktiengesellschaft | Condensed bicyclic heterocyclic derivatives as pest control agents |
| JP2022515896A (ja) | 2018-12-31 | 2022-02-22 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 硫黄含有置換基を有する殺有害生物的に活性な複素環式誘導体 |
| WO2020141135A1 (en) * | 2018-12-31 | 2020-07-09 | Syngenta Crop Protection Ag | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| TW202045011A (zh) * | 2019-02-28 | 2020-12-16 | 瑞士商先正達農作物保護公司 | 具有含硫取代基之殺有害生物活性雜環衍生物 |
| CN112062759B (zh) * | 2020-09-08 | 2021-11-23 | 浙江工业大学 | 含乙砜基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用 |
| CN111943944B (zh) * | 2020-09-08 | 2021-11-23 | 浙江工业大学 | 含乙硫基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用 |
| CN120882309A (zh) | 2023-03-14 | 2025-10-31 | 先正达农作物保护股份公司 | 对杀昆虫剂具有抗性的有害生物的控制 |
| WO2025010291A2 (en) * | 2023-07-03 | 2025-01-09 | The General Hospital Corporation | Targeted epigenetic therapies for disorders of progranulin deficiency |
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| BR8600161A (pt) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio |
| CA1340685C (en) | 1988-07-29 | 1999-07-27 | Frederick Meins | Dna sequences encoding polypeptides having beta-1,3-glucanase activity |
| US5169629A (en) | 1988-11-01 | 1992-12-08 | Mycogen Corporation | Process of controlling lepidopteran pests, using bacillus thuringiensis isolate denoted b.t ps81gg |
| EP0374753A3 (de) | 1988-12-19 | 1991-05-29 | American Cyanamid Company | Insektizide Toxine, Gene, die diese Toxine kodieren, Antikörper, die sie binden, sowie transgene Pflanzenzellen und transgene Pflanzen, die diese Toxine exprimieren |
| EP0392225B1 (en) | 1989-03-24 | 2003-05-28 | Syngenta Participations AG | Disease-resistant transgenic plants |
| GB8910624D0 (en) | 1989-05-09 | 1989-06-21 | Ici Plc | Bacterial strains |
| CA2015951A1 (en) | 1989-05-18 | 1990-11-18 | Mycogen Corporation | Novel bacillus thuringiensis isolates active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins |
| EP0427529B1 (en) | 1989-11-07 | 1995-04-19 | Pioneer Hi-Bred International, Inc. | Larvicidal lectins and plant insect resistance based thereon |
| US5639949A (en) | 1990-08-20 | 1997-06-17 | Ciba-Geigy Corporation | Genes for the synthesis of antipathogenic substances |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
| US5631072A (en) | 1995-03-10 | 1997-05-20 | Avondale Incorporated | Method and means for increasing efficacy and wash durability of insecticide treated fabric |
| DE19840337A1 (de) | 1998-09-04 | 2000-03-09 | Hoechst Schering Agrevo Gmbh | Benzoylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
| EP1114030B1 (en) | 1998-09-15 | 2005-06-01 | Syngenta Participations AG | Pyridine ketones useful as herbicides |
| AU2001285900B2 (en) | 2000-08-25 | 2005-02-17 | Syngenta Participations Ag | Novel insecticidal toxins derived from bacillus thuringiensis insecticidal crystal proteins |
| AU2002345250A1 (en) | 2001-06-22 | 2003-01-08 | Syngenta Participations Ag | Plant disease resistance genes |
| US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
| WO2003034823A1 (en) | 2001-10-25 | 2003-05-01 | Siamdutch Mosquito Netting Company Limited | Treatment of fabric materials with an insecticide |
| AR037856A1 (es) | 2001-12-17 | 2004-12-09 | Syngenta Participations Ag | Evento de maiz |
| US20050132500A1 (en) | 2003-12-22 | 2005-06-23 | Basf Aktiengesellschaft | Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests |
| DE102004023894A1 (de) | 2004-05-12 | 2005-12-08 | Basf Ag | Verfahren zur Behandlung von flexiblen Substraten |
| JP2008505167A (ja) | 2004-07-05 | 2008-02-21 | アステックス、セラピューティックス、リミテッド | 医薬組成物 |
| DE102005007160A1 (de) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen |
| DE102005020889A1 (de) | 2005-05-04 | 2006-11-09 | Fritz Blanke Gmbh & Co.Kg | Verfahren zur antimikrobiellen Ausrüstung von textilen Flächengebilden |
| UA85488C2 (ru) | 2005-06-03 | 2009-01-26 | Басф Акциенгезелльшафт | Инсектицидная композиция, ее применение для нанесения на неживой материал, способ пропитки, пропитанный материал и способ покрытия |
| EA014297B1 (ru) | 2005-10-25 | 2010-10-29 | Зингента Партисипейшнс Аг | Гетероциклические амиды, применимые в качестве микробиоцидов |
| PT1984555T (pt) | 2006-02-03 | 2016-08-18 | Basf Se | Processo para o tratamento de substratos têxteis |
| CA2682676A1 (en) | 2007-04-19 | 2008-10-30 | Novartis Ag | Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5 |
| WO2008151984A1 (en) | 2007-06-12 | 2008-12-18 | Basf Se | Aqueous formulation and process for the impregnation of non-living-materials imparting a protective activity against pests |
| JP5369854B2 (ja) | 2008-04-21 | 2013-12-18 | 住友化学株式会社 | 有害節足動物防除組成物および縮合複素環化合物 |
| JP2012514577A (ja) | 2008-12-26 | 2012-06-28 | グレンマーク ファーマシューティカルズ， エセ．アー． | Ｔｒｐｖ３アンタゴニストとしての縮合イミダゾール誘導体 |
| BRPI1015315B1 (pt) | 2009-04-28 | 2020-02-04 | Sumitomo Chemical Co | composto heterocíclico fundido, seu uso, composição e método de controlar um artrópode nocivo |
| EP2482660A4 (en) | 2009-09-30 | 2013-04-17 | Sumitomo Chemical Co | COMPOSITION AND METHOD FOR COMBATING HARMFUL ARTHROPODES |
| JP5540640B2 (ja) | 2009-10-07 | 2014-07-02 | 住友化学株式会社 | 複素環化合物及びその有害節足動物防除用途 |
| EP3006429B1 (en) | 2010-12-24 | 2019-02-06 | Sumitomo Chemical Co., Ltd. | Fused heterocyclic compound and use for pest control thereof |
| US20120309796A1 (en) | 2011-06-06 | 2012-12-06 | Fariborz Firooznia | Benzocycloheptene acetic acids |
| TWI545119B (zh) | 2011-08-04 | 2016-08-11 | 住友化學股份有限公司 | 稠合雜環化合物及其在病蟲害防制上之用途 |
| JP6217630B2 (ja) * | 2012-05-30 | 2017-10-25 | 住友化学株式会社 | 縮合複素環化合物 |
| WO2013180193A1 (ja) * | 2012-05-31 | 2013-12-05 | 住友化学株式会社 | 縮合複素環化合物 |
| JP6168055B2 (ja) | 2012-06-18 | 2017-07-26 | 住友化学株式会社 | 縮合複素環化合物 |
| UY35421A (es) | 2013-03-15 | 2014-10-31 | Nihon Nohyaku Co Ltd | Compuesto heterocíclico condensado o su sal, insecticida agrícola u hortícola que comprende el comp uesto y método de uso del insecticida |
| CA2917262A1 (en) | 2013-07-02 | 2015-01-08 | Syngenta Participations Ag | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
| CN107074846B (zh) * | 2014-08-12 | 2020-05-19 | 先正达参股股份有限公司 | 具有含硫取代基的杀有害生物活性杂环衍生物 |
| JP6949712B2 (ja) * | 2015-01-19 | 2021-10-13 | シンジェンタ パーティシペーションズ アーゲー | 硫黄含有置換基を有する殺有害生物的に活性な多環式誘導体 |
| EP3268365B8 (en) * | 2015-03-12 | 2019-04-03 | Syngenta Participations AG | Pesticidally active tetracyclic derivatives with sulfur containing substituents |
| ES2806459T3 (es) * | 2015-04-24 | 2021-02-17 | Syngenta Participations Ag | Derivados policíclicos activos como plaguicidas con heterociclos con anillos de cinco miembros sustituidos con azufre |
-
2016
- 2016-06-27 WO PCT/EP2016/064784 patent/WO2017001314A1/en not_active Ceased
- 2016-06-27 JP JP2017567321A patent/JP2018524336A/ja not_active Ceased
- 2016-06-27 CN CN201680038595.7A patent/CN107735396B/zh not_active Expired - Fee Related
- 2016-06-27 EP EP16731936.7A patent/EP3317276B1/en not_active Not-in-force
- 2016-06-27 US US15/732,803 patent/US10745396B2/en not_active Expired - Fee Related
- 2016-06-27 BR BR112017028600A patent/BR112017028600A2/pt not_active Application Discontinuation
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