JP2018523675A5 - - Google Patents

Info

Publication number

JP2018523675A5

JP2018523675A5 JP2018507672A JP2018507672A JP2018523675A5 JP 2018523675 A5 JP2018523675 A5 JP 2018523675A5 JP 2018507672 A JP2018507672 A JP 2018507672A JP 2018507672 A JP2018507672 A JP 2018507672A JP 2018523675 A5 JP2018523675 A5 JP 2018523675A5

Authority

JP

Japan

Prior art keywords

pharmaceutically acceptable

compound

pharmaceutical formulation

streptococcus

acceptable salt

Prior art date

2016-08-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 239000008194 pharmaceutical composition Substances 0.000 claims 8
• 208000035143 Bacterial infection Diseases 0.000 claims 7
• 208000022362 bacterial infectious disease Diseases 0.000 claims 7
• 150000001875 compounds Chemical class 0.000 claims 7
• 239000000825 pharmaceutical preparation Substances 0.000 claims 5
• 150000003839 salts Chemical class 0.000 claims 5
• QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical class N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 3
• 241000588770 Proteus mirabilis Species 0.000 claims 3
• 241000191967 Staphylococcus aureus Species 0.000 claims 3
• 239000003937 drug carrier Substances 0.000 claims 3
• 238000009472 formulation Methods 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• 241000588626 Acinetobacter baumannii Species 0.000 claims 2
• 241000589513 Burkholderia cepacia Species 0.000 claims 2
• 241000194032 Enterococcus faecalis Species 0.000 claims 2
• 241000194031 Enterococcus faecium Species 0.000 claims 2
• 241000588724 Escherichia coli Species 0.000 claims 2
• 241000606768 Haemophilus influenzae Species 0.000 claims 2
• 241000588915 Klebsiella aerogenes Species 0.000 claims 2
• 241000588747 Klebsiella pneumoniae Species 0.000 claims 2
• 241000589242 Legionella pneumophila Species 0.000 claims 2
• RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 2
• 241000588655 Moraxella catarrhalis Species 0.000 claims 2
• 241000589517 Pseudomonas aeruginosa Species 0.000 claims 2
• 241000607715 Serratia marcescens Species 0.000 claims 2
• 241000122973 Stenotrophomonas maltophilia Species 0.000 claims 2
• 241000193985 Streptococcus agalactiae Species 0.000 claims 2
• 241000193998 Streptococcus pneumoniae Species 0.000 claims 2
• 241000193996 Streptococcus pyogenes Species 0.000 claims 2
• 229940092559 enterobacter aerogenes Drugs 0.000 claims 2
• 229940032049 enterococcus faecalis Drugs 0.000 claims 2
• 229940047650 haemophilus influenzae Drugs 0.000 claims 2
• 229940115932 legionella pneumophila Drugs 0.000 claims 2
• 229960003085 meticillin Drugs 0.000 claims 2
• 229940031000 streptococcus pneumoniae Drugs 0.000 claims 2
• 208000019206 urinary tract infection Diseases 0.000 claims 2
• 241000217846 Bacteroides caccae Species 0.000 claims 1
• 241000606124 Bacteroides fragilis Species 0.000 claims 1
• 241001135228 Bacteroides ovatus Species 0.000 claims 1
• 241000315377 Bremia ovata Species 0.000 claims 1
• 241000588923 Citrobacter Species 0.000 claims 1
• 101710200331 Cytochrome b-245 chaperone 1 Proteins 0.000 claims 1
• 102100037186 Cytochrome b-245 chaperone 1 Human genes 0.000 claims 1
• 101710119396 Cytochrome b-245 chaperone 1 homolog Proteins 0.000 claims 1
• 241000588914 Enterobacter Species 0.000 claims 1
• 241000588697 Enterobacter cloacae Species 0.000 claims 1
• 241001505295 Eros Species 0.000 claims 1
• ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 1
• 241000588768 Providencia Species 0.000 claims 1
• 241000588777 Providencia rettgeri Species 0.000 claims 1
• 241000295644 Staphylococcaceae Species 0.000 claims 1
• 241000122971 Stenotrophomonas Species 0.000 claims 1
• 241000194017 Streptococcus Species 0.000 claims 1
• 210000003555 cloaca Anatomy 0.000 claims 1
• 241000894007 species Species 0.000 claims 1