JP2018518978A5 - - Google Patents

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Publication number
JP2018518978A5
JP2018518978A5 JP2017568133A JP2017568133A JP2018518978A5 JP 2018518978 A5 JP2018518978 A5 JP 2018518978A5 JP 2017568133 A JP2017568133 A JP 2017568133A JP 2017568133 A JP2017568133 A JP 2017568133A JP 2018518978 A5 JP2018518978 A5 JP 2018518978A5
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JP
Japan
Prior art keywords
cell according
mil
cell
antigen
receptor
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Application number
JP2017568133A
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English (en)
Japanese (ja)
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JP2018518978A (ja
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Priority claimed from PCT/US2016/041521 external-priority patent/WO2017008019A1/en
Publication of JP2018518978A publication Critical patent/JP2018518978A/ja
Publication of JP2018518978A5 publication Critical patent/JP2018518978A5/ja
Priority to JP2021095119A priority Critical patent/JP2021121230A/ja
Withdrawn legal-status Critical Current

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JP2017568133A 2015-07-08 2016-07-08 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ） Withdrawn JP2018518978A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021095119A JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ）

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562189928P 2015-07-08 2015-07-08
US62/189,928 2015-07-08
PCT/US2016/041521 WO2017008019A1 (en) 2015-07-08 2016-07-08 Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021095119A Division JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ）

Publications (2)

Publication Number Publication Date
JP2018518978A JP2018518978A (ja) 2018-07-19
JP2018518978A5 true JP2018518978A5 (enExample) 2019-08-15

Family

ID=57686063

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017568133A Withdrawn JP2018518978A (ja) 2015-07-08 2016-07-08 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ）
JP2021095119A Pending JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ）

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021095119A Pending JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体（ｃａｒ）療法のためのｔ細胞の供給源としての骨髄浸潤リンパ球（ｍｉｌ）

Country Status (12)

Country Link
US (3) US11478548B2 (enExample)
EP (1) EP3320087A4 (enExample)
JP (2) JP2018518978A (enExample)
KR (1) KR20180039068A (enExample)
CN (1) CN108026510A (enExample)
AU (1) AU2016291199B2 (enExample)
CA (1) CA2990694A1 (enExample)
HK (2) HK1255208A1 (enExample)
IL (1) IL256434B2 (enExample)
MA (1) MA42902A (enExample)
MX (1) MX2017017083A (enExample)
WO (1) WO2017008019A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017008019A1 (en) 2015-07-08 2017-01-12 The Johns Hopkins University Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
KR20200003913A (ko) * 2017-05-10 2020-01-10 이오반스 바이오테라퓨틱스, 인크. 액상 종양으로부터의 종양 침윤 림프구의 확장 및 그의 치료 용도
EP3714041A1 (en) * 2017-11-22 2020-09-30 Iovance Biotherapeutics, Inc. Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
US20190284553A1 (en) 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
JP2021516666A (ja) * 2018-03-22 2021-07-08 ウィンドミル セラピューティクス インコーポレイテッド 前立腺がん特異的髄浸潤リンパ球およびその使用
CN112638428A (zh) * 2018-06-12 2021-04-09 H·李·莫菲特癌症中心和研究所公司 嵌合抗原受体肿瘤浸润淋巴细胞
WO2020004337A1 (ja) * 2018-06-27 2020-01-02 国立大学法人名古屋大学 Ｃｄ３７特異的キメラ抗原レセプター
AU2019302603A1 (en) * 2018-07-13 2021-01-14 Nanjing Legend Biotech Co., Ltd. Co-receptor systems for treating infectious diseases
US20210338730A1 (en) * 2018-11-05 2021-11-04 Windmil Therapeutics, Inc. Marrow Infiltrating Lymphocytes With Increased Clonality and Uses Thereof
MX2021006399A (es) * 2018-11-30 2021-07-15 Windmil Therapeutics Inc Linfocitos infiltrantes de medula osea (mils) que expresan receptores de antigenos quimericos (car), metodo de fabricacion de los mismos y metodo de uso en terapia.
CN114072158A (zh) * 2019-03-22 2022-02-18 温德弥尔治疗公司 肺癌特异性骨髓浸润淋巴细胞及其用途
BR112022011795A2 (pt) 2019-12-20 2022-08-30 Instil Bio Uk Ltd Métodos para preparar e isolar uma população terapêutica de linfócitos e para tratar câncer em um indivíduo, população terapêutica de linfócitos, bolsa criopreservada, recipiente flexível, e, sistema para extração de linfócitos
US20230100744A1 (en) * 2020-02-28 2023-03-30 Windmil Therapeutics, Inc. Methods for enriching marrow infiltrating lymphocytes ("mils"), compositions containing enriched mils, and methods of using enriched mils
WO2022066872A1 (en) * 2020-09-24 2022-03-31 Windmil Therapeutics, Inc. Marrow infiltrating lymphocytes (mils) expressing t cell receptors, methods of manufacturing same, and method of using in therapy
WO2022076606A1 (en) * 2020-10-06 2022-04-14 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
JP2023546359A (ja) * 2020-10-06 2023-11-02 アイオバンス バイオセラピューティクス，インコーポレイテッド 腫瘍浸潤リンパ球療法によるｎｓｃｌｃ患者の治療
WO2022098985A1 (en) * 2020-11-05 2022-05-12 Windmil Therapeutics, Inc. Glioblastoma specific marrow infiltrating lymphocytes and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014085437A2 (en) * 2012-11-27 2014-06-05 The Johns Hopkins University Use of post-transplant cyclophosphamide treated allogeneic marrow infiltrating lymphocytes to augment anti-tumor immunity
EP2364152A4 (en) * 2008-11-03 2013-02-13 Univ Johns Hopkins METHOD FOR PRODUCING AND USING MARKINFILTRATING LYMPHOCYTES (MILS)
PH12013501201A1 (en) * 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
US9272002B2 (en) * 2011-10-28 2016-03-01 The Trustees Of The University Of Pennsylvania Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
EP2804625A4 (en) * 2012-01-17 2015-10-28 Univ Northeastern METHOD AND COMPOSITIONS FOR THE EXPANSION OF IMMUNOSUPPRESSIVE REGULATORY T CELLS IN VITRO AND USES THEREOF
JP2015524255A (ja) * 2012-07-13 2015-08-24 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 二重特異性抗体を共導入することによってｃａｒｔ細胞の活性を強化する方法
JP6647868B2 (ja) * 2013-02-20 2020-02-14 ノバルティス アーゲー ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
WO2015092024A2 (en) * 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
WO2016037054A1 (en) * 2014-09-04 2016-03-10 The Johns Hopkins University Activation of marrow infiltrating lymphocytes in hypoxic alternating with normoxic conditions
JP2018520679A (ja) * 2015-06-29 2018-08-02 ザ・ジョンズ・ホプキンス・ユニバーシティー 免疫チェックポイントキメラ抗原受容体療法
WO2017008019A1 (en) * 2015-07-08 2017-01-12 The Johns Hopkins University Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy

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