JP2021035366A5 - - Google Patents
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- JP2021035366A5 JP2021035366A5 JP2020173659A JP2020173659A JP2021035366A5 JP 2021035366 A5 JP2021035366 A5 JP 2021035366A5 JP 2020173659 A JP2020173659 A JP 2020173659A JP 2020173659 A JP2020173659 A JP 2020173659A JP 2021035366 A5 JP2021035366 A5 JP 2021035366A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- protein
- cell
- receptor
- homing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022161320A JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462036447P | 2014-08-12 | 2014-08-12 | |
| US62/036,447 | 2014-08-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Division JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022161320A Division JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021035366A JP2021035366A (ja) | 2021-03-04 |
| JP2021035366A5 true JP2021035366A5 (enExample) | 2021-06-17 |
Family
ID=55304746
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Pending JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
| JP2020173659A Pending JP2021035366A (ja) | 2014-08-12 | 2020-10-15 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ−ｔ細胞 |
| JP2022161320A Pending JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507842A Pending JP2017524365A (ja) | 2014-08-12 | 2015-08-11 | リンパ節のｂ細胞領域、皮膚、または腸管にホーミングするように操作されたｃａｒ−ｔ細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022161320A Pending JP2023011593A (ja) | 2014-08-12 | 2022-10-06 | リンパ節のｂ細胞領域、皮膚、または消化管にホーミングするように操作されたｃａｒ－ｔ細胞 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20180080008A1 (enExample) |
| EP (2) | EP3828267A3 (enExample) |
| JP (3) | JP2017524365A (enExample) |
| KR (2) | KR20170045244A (enExample) |
| CN (1) | CN106795497A (enExample) |
| AU (1) | AU2015301921A1 (enExample) |
| CA (1) | CA2957929A1 (enExample) |
| NZ (1) | NZ729046A (enExample) |
| SG (1) | SG11201701111SA (enExample) |
| TW (2) | TW202235619A (enExample) |
| WO (1) | WO2016025454A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| EP2970372B1 (en) | 2013-03-15 | 2020-09-30 | Celgene Corporation | Modified t lymphocytes |
| EP3770168A1 (en) | 2015-05-18 | 2021-01-27 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| EP3448995A1 (en) | 2016-04-25 | 2019-03-06 | Universität Basel | Allele editing and applications thereof |
| WO2018026953A1 (en) | 2016-08-02 | 2018-02-08 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| BR112019007100A2 (pt) | 2016-10-07 | 2019-06-25 | Tcr2 Therapeutics Inc | composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão |
| CN109983027A (zh) | 2016-10-20 | 2019-07-05 | 细胞基因公司 | 基于cereblon的可异二聚化嵌合抗原受体 |
| CN110177803A (zh) | 2016-11-22 | 2019-08-27 | T细胞受体治疗公司 | 用于使用融合蛋白进行tcr重新编程的组合物和方法 |
| AU2018223211B2 (en) * | 2017-02-21 | 2025-02-27 | Adelaide university | T cells expressing chemokine receptors for treating cancer |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| US11166985B2 (en) | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| BR112019023608A2 (pt) | 2017-05-12 | 2020-05-26 | Crispr Therapeutics Ag | Materiais e métodos para células manipuladas e seus usos em imuno-oncologia |
| US12384830B2 (en) | 2017-06-02 | 2025-08-12 | Regents Of The University Of Minnesota | Compositions and methods for improving immunotherapy |
| CN107287207B (zh) * | 2017-08-01 | 2019-02-26 | 上海优卡迪生物医药科技有限公司 | 一种用于体内示踪和人工清除car-t细胞的标签和应用 |
| WO2019032699A1 (en) * | 2017-08-09 | 2019-02-14 | Eureka Therapeutics, Inc. | CELLS EXPRESSING ANTIBODIES AND CELL SURFACE RECEPTORS |
| CA3072859A1 (en) * | 2017-08-23 | 2019-02-28 | Max-Delbruck-Centrum Fur Molekulare Medizin In Der Helmholtz-Gemeinscht | Chimeric antigen receptor and car-t cells that bind cxcr5 |
| WO2019056174A1 (zh) * | 2017-09-19 | 2019-03-28 | 中山大学 | 一种过表达cxcr5的间质干细胞及其制备方法和用途 |
| US12036273B2 (en) | 2018-01-08 | 2024-07-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Compositions and methods for targeting CD99-expressing cancers |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| US20200063100A1 (en) | 2018-05-11 | 2020-02-27 | Crispr Therapeutics Ag | Methods and compositions for treating cancer |
| US20220403001A1 (en) | 2018-06-12 | 2022-12-22 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| MX2021000617A (es) * | 2018-07-18 | 2021-04-13 | Amgen Inc | Receptores quimericos de steap1 y metodos de uso de los mismos. |
| CN109666074B (zh) * | 2018-12-29 | 2020-04-24 | 广州百暨基因科技有限公司 | 一种趋化因子受体cxcr5的用途 |
| WO2020182681A1 (en) * | 2019-03-08 | 2020-09-17 | Klinikum Der Universität München | Ccr8 expressing lymphocytes for targeted tumor therapy |
| CA3138633A1 (en) | 2019-04-30 | 2020-11-05 | Crispr Therapeutics Ag | Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19 |
| AU2020382219A1 (en) | 2019-11-13 | 2022-05-12 | Crispr Therapeutics Ag | Manufacturing process for making T cells expressing chimeric antigen receptors |
| IL301078A (en) * | 2020-09-02 | 2023-05-01 | Walking Fish Therapeutics | Modified B cells and methods of using them |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US5665577A (en) | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| ATE368122T1 (de) | 1999-04-29 | 2007-08-15 | Cell Genesys Inc | Verfahren und mittel für die herstellung von sicheren rekombinanten lentiviralen vektoren mit hohem titer |
| AU2002251935B2 (en) | 2001-02-14 | 2007-11-29 | Celularity Inc. | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| JP2006521325A (ja) * | 2003-03-24 | 2006-09-21 | タップ ファーマシューティカル プロダクツ インコーポレイテッド | 幹細胞移植に対するケモカイン受容体アゴニストの新規な使用 |
| JP2005336062A (ja) * | 2004-05-24 | 2005-12-08 | Mitsubishi Chemicals Corp | Ｔ細胞の腸組織へのホーミング誘導剤 |
| KR20180105266A (ko) | 2005-12-29 | 2018-09-27 | 안트로제네시스 코포레이션 | 태반 줄기 세포 집단 |
| WO2010003002A2 (en) * | 2008-07-02 | 2010-01-07 | Board Of Regents, The University Of Texas System | Modulation of follicular helper t cells |
| EP2814846B1 (en) * | 2012-02-13 | 2020-01-08 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| CN110241086A (zh) * | 2012-06-11 | 2019-09-17 | 威尔逊沃夫制造公司 | 用于过继细胞疗法的改进的细胞培养方法 |
| CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
| US11471486B2 (en) * | 2012-09-04 | 2022-10-18 | Inven2 As | Selective and controlled expansion of educated NK cells |
| US9393268B2 (en) * | 2013-03-15 | 2016-07-19 | Thomas Jefferson University | Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same |
-
2015
- 2015-08-11 CA CA2957929A patent/CA2957929A1/en active Pending
- 2015-08-11 KR KR1020177006518A patent/KR20170045244A/ko not_active Ceased
- 2015-08-11 NZ NZ729046A patent/NZ729046A/en not_active IP Right Cessation
- 2015-08-11 EP EP20195244.7A patent/EP3828267A3/en not_active Withdrawn
- 2015-08-11 AU AU2015301921A patent/AU2015301921A1/en not_active Abandoned
- 2015-08-11 KR KR1020227037473A patent/KR20220150428A/ko not_active Ceased
- 2015-08-11 CN CN201580055115.3A patent/CN106795497A/zh active Pending
- 2015-08-11 WO PCT/US2015/044611 patent/WO2016025454A2/en not_active Ceased
- 2015-08-11 JP JP2017507842A patent/JP2017524365A/ja active Pending
- 2015-08-11 SG SG11201701111SA patent/SG11201701111SA/en unknown
- 2015-08-11 EP EP15831772.7A patent/EP3194579A4/en not_active Withdrawn
- 2015-08-11 US US15/502,752 patent/US20180080008A1/en not_active Abandoned
- 2015-08-12 TW TW110145417A patent/TW202235619A/zh unknown
- 2015-08-12 TW TW104126314A patent/TW201614072A/zh unknown
-
2020
- 2020-09-30 US US17/039,507 patent/US20210254003A1/en not_active Abandoned
- 2020-10-15 JP JP2020173659A patent/JP2021035366A/ja active Pending
-
2022
- 2022-10-06 JP JP2022161320A patent/JP2023011593A/ja active Pending
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