JP2018533604A5 - - Google Patents

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Publication number
JP2018533604A5
JP2018533604A5 JP2018524447A JP2018524447A JP2018533604A5 JP 2018533604 A5 JP2018533604 A5 JP 2018533604A5 JP 2018524447 A JP2018524447 A JP 2018524447A JP 2018524447 A JP2018524447 A JP 2018524447A JP 2018533604 A5 JP2018533604 A5 JP 2018533604A5
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JP
Japan
Prior art keywords
cancer
arenavirus
tumor
protein
segment
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Application number
JP2018524447A
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English (en)
Japanese (ja)
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JP2018533604A (ja
JP7157662B2 (ja
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Priority claimed from PCT/EP2016/076668 external-priority patent/WO2017080920A1/en
Publication of JP2018533604A publication Critical patent/JP2018533604A/ja
Publication of JP2018533604A5 publication Critical patent/JP2018533604A5/ja
Priority to JP2021179213A priority Critical patent/JP2022033736A/ja
Application granted granted Critical
Publication of JP7157662B2 publication Critical patent/JP7157662B2/ja
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JP2018524447A 2015-11-12 2016-11-04 癌ワクチンとしてのアレナウイルス粒子 Active JP7157662B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021179213A JP2022033736A (ja) 2015-11-12 2021-11-02 癌ワクチンとしてのアレナウイルス粒子

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562254654P 2015-11-12 2015-11-12
US201562254651P 2015-11-12 2015-11-12
US62/254,654 2015-11-12
US62/254,651 2015-11-12
PCT/EP2016/076668 WO2017080920A1 (en) 2015-11-12 2016-11-04 Arenavirus particles as cancer vaccines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021179213A Division JP2022033736A (ja) 2015-11-12 2021-11-02 癌ワクチンとしてのアレナウイルス粒子

Publications (3)

Publication Number Publication Date
JP2018533604A JP2018533604A (ja) 2018-11-15
JP2018533604A5 true JP2018533604A5 (enExample) 2020-04-09
JP7157662B2 JP7157662B2 (ja) 2022-10-20

Family

ID=57345877

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018524447A Active JP7157662B2 (ja) 2015-11-12 2016-11-04 癌ワクチンとしてのアレナウイルス粒子
JP2021179213A Pending JP2022033736A (ja) 2015-11-12 2021-11-02 癌ワクチンとしてのアレナウイルス粒子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021179213A Pending JP2022033736A (ja) 2015-11-12 2021-11-02 癌ワクチンとしてのアレナウイルス粒子

Country Status (17)

Country Link
US (2) US11266727B2 (enExample)
EP (2) EP3373959B1 (enExample)
JP (2) JP7157662B2 (enExample)
CN (1) CN108697775B (enExample)
AU (1) AU2016352572B2 (enExample)
CA (1) CA3003548A1 (enExample)
CY (1) CY1125526T1 (enExample)
DK (1) DK3373959T3 (enExample)
ES (1) ES2922981T3 (enExample)
HR (1) HRP20221167T1 (enExample)
HU (1) HUE059589T2 (enExample)
LT (1) LT3373959T (enExample)
PL (1) PL3373959T3 (enExample)
PT (1) PT3373959T (enExample)
RS (1) RS63546B1 (enExample)
SI (1) SI3373959T1 (enExample)
WO (1) WO2017080920A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103993012B (zh) 2007-12-27 2023-01-10 苏黎士大学 复制缺陷型沙粒病毒载体
RS61993B1 (sr) 2013-12-03 2021-07-30 Hookipa Biotech Gmbh Cmv vakcine
ES2811093T3 (es) * 2014-11-13 2021-03-10 Univ Geneve Arenavirus trisegmentados como vectores de vacunas
HK1246183A1 (zh) 2015-06-10 2018-09-07 Hookipa Biotech Gmbh Hpv疫苗
WO2018045029A1 (en) * 2016-09-02 2018-03-08 The United States Of America, As Represented By The Secretary Of The Army Pan south american arenavirus live attenuated vaccine
WO2017076988A1 (en) 2015-11-04 2017-05-11 Hookipa Biotech Ag Vaccines against hepatitis b virus
EP3373959B1 (en) 2015-11-12 2022-06-29 Hookipa Biotech GmbH Arenavirus particles as cancer vaccines
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
CN110719788A (zh) * 2017-04-07 2020-01-21 霍欧奇帕生物科技有限公司 治疗实体瘤的沙粒病毒颗粒
US20210369635A1 (en) * 2017-11-29 2021-12-02 Adaptive Phage Therapeutics, Inc. Novel methods of vaccination using icosahedral phage
WO2020255023A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Arenavirus vectors for hepatitis b virus (hbv) vaccines and uses thereof
CN114981443A (zh) * 2019-11-07 2022-08-30 巴塞尔大学 作为载体的沙粒病毒
EP4069271A1 (en) 2019-12-07 2022-10-12 ISA Pharmaceuticals B.V. Treatment of diseases related to hepatitis b virus
IL298420A (en) 2020-05-29 2023-01-01 Hookipa Biotech Gmbh Cancer treatment strategies using RNA virus vectors
WO2022180203A1 (en) * 2021-02-26 2022-09-01 Abalos Therapeutics Gmbh New virus particles for therapeutic purposes
MX2023011054A (es) 2021-03-23 2023-11-22 Hookipa Biotech Gmbh Arenavirus utilizados en tratamientos del cáncer de próstata.
EP4475879A1 (en) * 2022-02-08 2024-12-18 Hookipa Biotech GmbH Combination therapy with arenavirus particles and immune checkpoint modulators or cytokines
EP4701650A2 (en) 2023-04-26 2026-03-04 Isabella Pharma B.V. Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
JPH1084967A (ja) 1996-09-19 1998-04-07 Fujirebio Inc B型肝炎のe抗原
FR2803599B1 (fr) 2000-01-06 2004-11-19 Inst Nat Sante Rech Med Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications
DE60334303D1 (de) * 2002-07-03 2010-11-04 Tasuku Honjo Immunpotenzierende zusammensetzungen
EP3530736A3 (en) 2005-05-09 2019-11-06 ONO Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
WO2006125983A1 (en) 2005-05-23 2006-11-30 Oxxon Therapeutics Ltd Compositions for inducing an immune response against hepatitis b
CA2646891A1 (en) 2006-03-23 2007-09-27 Novartis Ag Immunopotentiating compounds
ATE539079T1 (de) 2006-03-23 2012-01-15 Novartis Ag Imidazochinoxalinverbindungen als immunmodulatoren
CA2673870A1 (en) * 2006-12-27 2008-07-10 Emory University Compositions and methods for the treatment of infections and tumors
CN103993012B (zh) * 2007-12-27 2023-01-10 苏黎士大学 复制缺陷型沙粒病毒载体
CA2770075C (en) 2009-08-07 2021-08-24 Perrine Martin Composition for treating hbv infection
GB201001726D0 (en) 2010-02-03 2010-03-24 Univ St Andrews Bunyavirus vaccine
WO2012162428A1 (en) 2011-05-23 2012-11-29 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Prime-boost vaccination for viral infection
CN104159607A (zh) 2012-01-24 2014-11-19 桑福德研究院/南达科他大学 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸
US9809801B2 (en) 2013-03-15 2017-11-07 Université De Genève Anti-mycobacterial vaccines
GB201305361D0 (en) 2013-03-25 2013-05-08 Univ Edinburgh Enhanced expression
RS61993B1 (sr) 2013-12-03 2021-07-30 Hookipa Biotech Gmbh Cmv vakcine
WO2015103602A1 (en) * 2014-01-06 2015-07-09 The Trustees Of The University Of Pennsylvania Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy
US10342861B2 (en) 2014-05-27 2019-07-09 University Of Rochester Arenavirus vaccine
US9943585B2 (en) 2014-07-30 2018-04-17 University Of Rochester Methods and compositions related to reorganization of arenavirus genome for development of novel arenavirus live-attenuated vaccines (LAV)
BR112017005744B1 (pt) 2014-09-22 2023-11-28 Regents Of The University Of Minnesota "vírus pichinde geneticamente manipulado, método de fabricação e uso do mesmo, partícula viral infecciosa, composição, coleção de vetores, sistema de genética reversa e método de uso do mesmo"
GB201419572D0 (en) 2014-11-03 2014-12-17 Pirbright Inst The Virus
ES2811093T3 (es) * 2014-11-13 2021-03-10 Univ Geneve Arenavirus trisegmentados como vectores de vacunas
KR102698184B1 (ko) * 2015-01-29 2024-08-23 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 관문 억제제 및 백신 조합 및 면역요법을 위한 이들의 사용
DE102015207036A1 (de) 2015-04-17 2016-10-20 Karl Sebastian Lang Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften
HK1246183A1 (zh) 2015-06-10 2018-09-07 Hookipa Biotech Gmbh Hpv疫苗
US10849969B2 (en) 2015-10-23 2020-12-01 Institut Pasteur Recombinant attenuated Mopeia virus comprising a modified nucleoprotein with reduced exonuclease activity
WO2017076988A1 (en) 2015-11-04 2017-05-11 Hookipa Biotech Ag Vaccines against hepatitis b virus
EP3373959B1 (en) 2015-11-12 2022-06-29 Hookipa Biotech GmbH Arenavirus particles as cancer vaccines
WO2017190074A1 (en) 2016-04-28 2017-11-02 The University Of Chicago Lymphangiogenesis for therapeutic immunomodulation
IL262963B2 (en) 2016-05-18 2025-01-01 Hookipa Biotech Gmbh Trisegmented PICHINDE viruses as vaccine vectors
CN110167586B (zh) 2016-11-04 2024-01-30 霍欧奇帕生物科技有限公司 作为癌症疫苗的复制-缺陷型沙粒病毒颗粒和三-节段沙粒病毒颗粒
CN110719788A (zh) 2017-04-07 2020-01-21 霍欧奇帕生物科技有限公司 治疗实体瘤的沙粒病毒颗粒
CN114981443A (zh) 2019-11-07 2022-08-30 巴塞尔大学 作为载体的沙粒病毒

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