SI3373959T1 - Arenavirusni delci kot cepiva proti raku - Google Patents
Arenavirusni delci kot cepiva proti rakuInfo
- Publication number
- SI3373959T1 SI3373959T1 SI201631604T SI201631604T SI3373959T1 SI 3373959 T1 SI3373959 T1 SI 3373959T1 SI 201631604 T SI201631604 T SI 201631604T SI 201631604 T SI201631604 T SI 201631604T SI 3373959 T1 SI3373959 T1 SI 3373959T1
- Authority
- SI
- Slovenia
- Prior art keywords
- cancer vaccines
- arenavirus particles
- arenavirus
- particles
- vaccines
- Prior art date
Links
- 241000712891 Arenavirus Species 0.000 title 1
- 229940022399 cancer vaccine Drugs 0.000 title 1
- 238000009566 cancer vaccine Methods 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
Classifications
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- A61K39/0011—Cancer antigens
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- Organic Chemistry (AREA)
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- Vascular Medicine (AREA)
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- Plant Pathology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562254654P | 2015-11-12 | 2015-11-12 | |
US201562254651P | 2015-11-12 | 2015-11-12 | |
PCT/EP2016/076668 WO2017080920A1 (en) | 2015-11-12 | 2016-11-04 | Arenavirus particles as cancer vaccines |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20221475T3 (hr) | 2007-12-27 | 2023-01-06 | Universität Zürich | Replikacijski defektni vektori arenavirusa |
PT3077519T (pt) | 2013-12-03 | 2021-05-13 | Hookipa Biotech Ag | Vacinas contra cmv |
AU2015345080B2 (en) * | 2014-11-13 | 2022-01-27 | Universite De Geneve | Tri-segmented arenaviruses as vaccine vectors |
AU2016274655B2 (en) | 2015-06-10 | 2021-06-17 | Hookipa Biotech Gmbh | HPV vaccines |
WO2018045029A1 (en) * | 2016-09-02 | 2018-03-08 | The United States Of America, As Represented By The Secretary Of The Army | Pan south american arenavirus live attenuated vaccine |
FI3371316T3 (fi) | 2015-11-04 | 2023-01-13 | Rokotteita hepatiitti b -virusta vastaan | |
CN108697775B (zh) | 2015-11-12 | 2023-05-09 | 霍欧奇帕生物科技有限公司 | 作为癌症疫苗的沙粒病毒颗粒 |
TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
AU2018247958A1 (en) * | 2017-04-07 | 2019-10-10 | Hookipa Biotech Gmbh | Arenavirus particles to treat solid tumors |
US20210369635A1 (en) * | 2017-11-29 | 2021-12-02 | Adaptive Phage Therapeutics, Inc. | Novel methods of vaccination using icosahedral phage |
WO2020255023A1 (en) | 2019-06-18 | 2020-12-24 | Janssen Sciences Ireland Unlimited Company | Arenavirus vectors for hepatitis b virus (hbv) vaccines and uses thereof |
WO2021089853A1 (en) * | 2019-11-07 | 2021-05-14 | Universität Basel | Arenaviruses as vectors |
CA3160755A1 (en) | 2019-12-07 | 2021-06-10 | Sonja Ingrid BUSCHOW | Treatment of diseases related to hepatitis b virus |
IL298420A (en) | 2020-05-29 | 2023-01-01 | Hookipa Biotech Gmbh | Cancer treatment strategies using RNA virus vectors |
CN117280027A (zh) | 2021-03-23 | 2023-12-22 | 霍欧奇帕生物科技有限公司 | 用于治疗前列腺癌的沙粒病毒 |
WO2023152116A1 (en) * | 2022-02-08 | 2023-08-17 | Hookipa Biotech Gmbh | Combination therapy with arenavirus particles and immune checkpoint modulators or cytokines |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
JPH1084967A (ja) | 1996-09-19 | 1998-04-07 | Fujirebio Inc | B型肝炎のe抗原 |
FR2803599B1 (fr) | 2000-01-06 | 2004-11-19 | Inst Nat Sante Rech Med | Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications |
DE10161767T1 (de) | 2002-07-03 | 2018-06-07 | Honjo Tasuku | Immunopotenzierende Zusammensetzungen, die einen Anti-PD-L1 Antikörper enthalten |
NZ563193A (en) | 2005-05-09 | 2010-05-28 | Ono Pharmaceutical Co | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
WO2006125983A1 (en) | 2005-05-23 | 2006-11-30 | Oxxon Therapeutics Ltd | Compositions for inducing an immune response against hepatitis b |
CA2646891A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Immunopotentiating compounds |
EP2357184B1 (en) | 2006-03-23 | 2015-02-25 | Novartis AG | Imidazoquinoxaline compounds as immunomodulators |
CN101663323A (zh) * | 2006-12-27 | 2010-03-03 | 埃默里大学 | 用于治疗传染病和肿瘤的组合物和方法 |
HRP20221475T3 (hr) | 2007-12-27 | 2023-01-06 | Universität Zürich | Replikacijski defektni vektori arenavirusa |
NZ598000A (en) | 2009-08-07 | 2013-10-25 | Transgene Sa | Composition for treating hbv infection |
GB201001726D0 (en) | 2010-02-03 | 2010-03-24 | Univ St Andrews | Bunyavirus vaccine |
WO2012162428A1 (en) | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
CN110042110A (zh) | 2012-01-24 | 2019-07-23 | 桑福德健康公司 | 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸 |
EP2968506B1 (en) | 2013-03-15 | 2019-07-31 | Université de Genève | Anti-mycobacterial vaccines |
GB201305361D0 (en) | 2013-03-25 | 2013-05-08 | Univ Edinburgh | Enhanced expression |
PT3077519T (pt) | 2013-12-03 | 2021-05-13 | Hookipa Biotech Ag | Vacinas contra cmv |
CA2935375C (en) * | 2014-01-06 | 2023-08-08 | The Trustees Of The University Of Pennsylvania | Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy |
US10342861B2 (en) | 2014-05-27 | 2019-07-09 | University Of Rochester | Arenavirus vaccine |
US9943585B2 (en) | 2014-07-30 | 2018-04-17 | University Of Rochester | Methods and compositions related to reorganization of arenavirus genome for development of novel arenavirus live-attenuated vaccines (LAV) |
EP3198008B1 (en) | 2014-09-22 | 2019-05-29 | Regents of the University of Minnesota | Pichinde virus reverse genetics system and methods of use |
GB201419572D0 (en) | 2014-11-03 | 2014-12-17 | Pirbright Inst The | Virus |
AU2015345080B2 (en) * | 2014-11-13 | 2022-01-27 | Universite De Geneve | Tri-segmented arenaviruses as vaccine vectors |
WO2016123285A1 (en) * | 2015-01-29 | 2016-08-04 | The Trustees Of The University Of Pennsylvania | Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy |
DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
AU2016274655B2 (en) | 2015-06-10 | 2021-06-17 | Hookipa Biotech Gmbh | HPV vaccines |
EP3365005A1 (en) | 2015-10-23 | 2018-08-29 | Institut Pasteur | Recombinant mopeia virus and vaccine platform |
FI3371316T3 (fi) | 2015-11-04 | 2023-01-13 | Rokotteita hepatiitti b -virusta vastaan | |
CN108697775B (zh) | 2015-11-12 | 2023-05-09 | 霍欧奇帕生物科技有限公司 | 作为癌症疫苗的沙粒病毒颗粒 |
US10980877B2 (en) | 2016-04-28 | 2021-04-20 | The University Of Chicago | Method for treating melanoma using lymphangiogenesis inducers and a melanoma-specific antigen |
CA3023599A1 (en) | 2016-05-18 | 2017-11-23 | Hookipa Biotech Gmbh | Tri-segmented pichinde viruses as vaccine vectors |
EP3534943A2 (en) | 2016-11-04 | 2019-09-11 | Hookipa Biotech GmbH | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
AU2018247958A1 (en) | 2017-04-07 | 2019-10-10 | Hookipa Biotech Gmbh | Arenavirus particles to treat solid tumors |
WO2021089853A1 (en) | 2019-11-07 | 2021-05-14 | Universität Basel | Arenaviruses as vectors |
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CN108697775B (zh) | 2023-05-09 |
HRP20221167T1 (hr) | 2022-12-09 |
JP2022033736A (ja) | 2022-03-02 |
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AU2016352572A1 (en) | 2018-05-17 |
DK3373959T3 (da) | 2022-09-19 |
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LT3373959T (lt) | 2022-07-25 |
WO2017080920A1 (en) | 2017-05-18 |
ES2922981T3 (es) | 2022-09-22 |
EP3373959B1 (en) | 2022-06-29 |
PT3373959T (pt) | 2022-08-09 |
US11266727B2 (en) | 2022-03-08 |
EP3960197A1 (en) | 2022-03-02 |
AU2016352572B2 (en) | 2023-10-19 |
CA3003548A1 (en) | 2017-05-18 |
JP7157662B2 (ja) | 2022-10-20 |
US20220257734A1 (en) | 2022-08-18 |
RS63546B1 (sr) | 2022-09-30 |
PL3373959T3 (pl) | 2022-10-24 |
EP3373959A1 (en) | 2018-09-19 |
US20180344830A1 (en) | 2018-12-06 |
CN108697775A (zh) | 2018-10-23 |
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