JP2018518978A - キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil) - Google Patents

キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil) Download PDF

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JP2018518978A
JP2018518978A JP2017568133A JP2017568133A JP2018518978A JP 2018518978 A JP2018518978 A JP 2018518978A JP 2017568133 A JP2017568133 A JP 2017568133A JP 2017568133 A JP2017568133 A JP 2017568133A JP 2018518978 A JP2018518978 A JP 2018518978A
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mil
cell
cells
antigen
car
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JP2018518978A5 (enExample
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イヴァン エム. ボレロ,
イヴァン エム. ボレロ,
スーザン リー,
スーザン リー,
キンバリー エー. ヌーナン,
キンバリー エー. ヌーナン,
ドリュー エム. パードール,
ドリュー エム. パードール,
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ザ・ジョンズ・ホプキンス・ユニバーシティー
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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JP2017568133A 2015-07-08 2016-07-08 キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil) Withdrawn JP2018518978A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021095119A JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562189928P 2015-07-08 2015-07-08
US62/189,928 2015-07-08
PCT/US2016/041521 WO2017008019A1 (en) 2015-07-08 2016-07-08 Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy

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JP2021095119A Division JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil)

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JP2018518978A true JP2018518978A (ja) 2018-07-19
JP2018518978A5 JP2018518978A5 (enExample) 2019-08-15

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JP2017568133A Withdrawn JP2018518978A (ja) 2015-07-08 2016-07-08 キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil)
JP2021095119A Pending JP2021121230A (ja) 2015-07-08 2021-06-07 キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil)

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US (3) US11478548B2 (enExample)
EP (1) EP3320087A4 (enExample)
JP (2) JP2018518978A (enExample)
KR (1) KR20180039068A (enExample)
CN (1) CN108026510A (enExample)
AU (1) AU2016291199B2 (enExample)
CA (1) CA2990694A1 (enExample)
HK (2) HK1254313A1 (enExample)
IL (1) IL256434B2 (enExample)
MA (1) MA42902A (enExample)
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Cited By (1)

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JP2022513687A (ja) * 2018-11-30 2022-02-09 ウィンドミル セラピューティクス インコーポレイテッド キメラ抗原受容体(car)を発現する骨髄浸潤リンパ球(mil)、その製造方法および治療における使用方法

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WO2017008019A1 (en) * 2015-07-08 2017-01-12 The Johns Hopkins University Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
WO2018209115A1 (en) * 2017-05-10 2018-11-15 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
JP2021503885A (ja) * 2017-11-22 2021-02-15 アイオバンス バイオセラピューティクス,インコーポレイテッド 末梢血からの末梢血リンパ球(pbl)の拡大培養
EP3765094A4 (en) 2018-03-15 2021-12-22 KSQ Therapeutics, Inc. GENE REGULATORY COMPOSITIONS AND PROCEDURES FOR IMPROVED IMMUNOTHERAPY
US20210000876A1 (en) * 2018-03-22 2021-01-07 Windmil Therapeutics, Inc. Prostate Cancer Specific Marrow Infiltrating Lymphocytes and Uses Thereof
CN112638428A (zh) * 2018-06-12 2021-04-09 H·李·莫菲特癌症中心和研究所公司 嵌合抗原受体肿瘤浸润淋巴细胞
JPWO2020004337A1 (ja) * 2018-06-27 2021-08-02 国立大学法人東海国立大学機構 Cd37特異的キメラ抗原レセプター
KR20210031898A (ko) * 2018-07-13 2021-03-23 난징 레전드 바이오테크 씨오., 엘티디. 전염병을 치료하기 위한 공동수용체 시스템
JP2022507113A (ja) * 2018-11-05 2022-01-18 ウィンドミル セラピューティクス インコーポレイテッド クローン性の増大した骨髄浸潤リンパ球およびそれらの使用
CN114072158A (zh) * 2019-03-22 2022-02-18 温德弥尔治疗公司 肺癌特异性骨髓浸润淋巴细胞及其用途
JP2023507432A (ja) 2019-12-20 2023-02-22 インスティル バイオ (ユーケイ) リミテッド 腫瘍浸潤リンパ球を単離するためのデバイスおよび方法ならびにそれらの使用
US20230100744A1 (en) * 2020-02-28 2023-03-30 Windmil Therapeutics, Inc. Methods for enriching marrow infiltrating lymphocytes ("mils"), compositions containing enriched mils, and methods of using enriched mils
WO2022066872A1 (en) * 2020-09-24 2022-03-31 Windmil Therapeutics, Inc. Marrow infiltrating lymphocytes (mils) expressing t cell receptors, methods of manufacturing same, and method of using in therapy
WO2022076606A1 (en) * 2020-10-06 2022-04-14 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
CA3195019A1 (en) 2020-10-06 2022-04-14 Maria Fardis Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
WO2022098985A1 (en) * 2020-11-05 2022-05-12 Windmil Therapeutics, Inc. Glioblastoma specific marrow infiltrating lymphocytes and uses thereof

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