JP2020508663A5 - - Google Patents

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Publication number
JP2020508663A5
JP2020508663A5 JP2019545731A JP2019545731A JP2020508663A5 JP 2020508663 A5 JP2020508663 A5 JP 2020508663A5 JP 2019545731 A JP2019545731 A JP 2019545731A JP 2019545731 A JP2019545731 A JP 2019545731A JP 2020508663 A5 JP2020508663 A5 JP 2020508663A5
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JP
Japan
Prior art keywords
antigen
fragment
antibody
tumor
binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019545731A
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English (en)
Japanese (ja)
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JP2020508663A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/019281 external-priority patent/WO2018156802A1/en
Publication of JP2020508663A publication Critical patent/JP2020508663A/ja
Publication of JP2020508663A5 publication Critical patent/JP2020508663A5/ja
Pending legal-status Critical Current

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JP2019545731A 2017-02-22 2018-02-22 癌の治療のための組成物及び方法 Pending JP2020508663A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762462098P 2017-02-22 2017-02-22
US62/462,098 2017-02-22
US201762541439P 2017-08-04 2017-08-04
US62/541,439 2017-08-04
PCT/US2018/019281 WO2018156802A1 (en) 2017-02-22 2018-02-22 Compositions and methods for treatment of cancer

Publications (2)

Publication Number Publication Date
JP2020508663A JP2020508663A (ja) 2020-03-26
JP2020508663A5 true JP2020508663A5 (enExample) 2021-04-08

Family

ID=63253021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019545731A Pending JP2020508663A (ja) 2017-02-22 2018-02-22 癌の治療のための組成物及び方法

Country Status (13)

Country Link
US (1) US20210130494A1 (enExample)
EP (1) EP3585817A4 (enExample)
JP (1) JP2020508663A (enExample)
KR (1) KR20200003367A (enExample)
CN (1) CN110637033A (enExample)
AU (1) AU2018225164A1 (enExample)
BR (1) BR112019017403A2 (enExample)
CA (1) CA3054304A1 (enExample)
CL (1) CL2019002368A1 (enExample)
IL (1) IL268814A (enExample)
MA (1) MA47613A (enExample)
MX (1) MX2019010040A (enExample)
WO (1) WO2018156802A1 (enExample)

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Publication number Priority date Publication date Assignee Title
IL270743B2 (en) 2017-05-19 2024-09-01 Wuxi Biologics Shanghai Co Ltd Monoclonal antibodies to cytotoxic t-lymphocyte-associated protein 4 (ctla-4), compositions containing same and uses thereof
WO2019118918A1 (en) * 2017-12-15 2019-06-20 Aleta Biotherapeutics Inc. Cd19 variants
CN109504660B (zh) * 2018-11-02 2021-08-06 温州启星生物技术有限公司 一种第四代car-t细胞及其构建方法和应用
JP7649239B2 (ja) * 2018-11-30 2025-03-19 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド キメラ抗原受容体ファクトリおよびその使用方法
WO2020113063A1 (en) 2018-11-30 2020-06-04 Aleta Biotherapeutics Inc. Single domain antibodies against cll-1
BR112021012631A2 (pt) 2018-12-26 2021-12-14 Xilio Dev Inc Anticorpos anti-ctla4 e métodos de uso dos mesmos
US12590135B2 (en) 2019-03-01 2026-03-31 Universität Für Bodenkultur Wien Stabilized extracellular domain of CD19
CN110256582B (zh) * 2019-07-10 2021-09-17 杭州普科亭生物医药有限公司 包含cd28和4-1bb的嵌合抗原受体及其应用
US12702708B2 (en) 2019-08-21 2026-08-11 Innovative Cellular Therapeutics Holdings, Ltd. Presenting cell and use thereof in cell therapy
WO2021113776A1 (en) * 2019-12-06 2021-06-10 Juno Therapeutics, Inc. Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
CN122150591A (zh) * 2020-06-08 2026-06-05 詹森生物科技公司 用于测定表达嵌合抗原的免疫细胞的体外肿瘤杀伤活性的基于细胞的测定法
EP4210733B1 (en) 2020-09-04 2024-11-06 Miltenyi Biotec B.V. & Co. KG System for inducible expression of an adapter in immune cells
EP4211164A1 (en) 2020-09-14 2023-07-19 Vor Biopharma Inc. Single domain antibodies against cd33
TW202241935A (zh) 2020-12-18 2022-11-01 美商世紀治療股份有限公司 具有可調適受體專一性之嵌合抗原受體系統
CN115128267B (zh) * 2021-03-25 2025-11-14 青岛海兰深生物科技有限公司 检测抗乳腺癌天然抗体的检测试剂、试剂盒及其应用
US20240181055A1 (en) * 2021-04-08 2024-06-06 Crage Medical Co., Limited Cellular immunotherapy use
BR112023025020A2 (pt) * 2021-06-01 2024-02-20 Janssen Biotech Inc Anticorpos anti-idiotípicos contra anticorpos anti-cd79b
JP2025513855A (ja) 2022-04-11 2025-04-30 ブイオーアール バイオファーマ インコーポレーテッド 結合剤及びその使用方法
CN115725738B (zh) * 2022-08-17 2026-06-12 深圳市龙岗区耳鼻咽喉医院 一种长链非编码rna分子标志物组合及其应用
EP4713363A1 (en) 2023-05-15 2026-03-25 Syzygymed Inc Egf-like module containing mucin-like hormone-like 2 (erm2) binding agents and methods of use thereof
EP4470555A1 (en) 2023-05-31 2024-12-04 Miltenyi Biotec B.V. & Co. KG Anti-tag chimeric antigen receptors with specificity for mutated peptides derived from human fgfr2
WO2026131594A1 (en) * 2024-12-19 2026-06-25 Lakefront Biotherapeutics Nv Novel bispecific anti cd19-cd20 car-t constructs and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034636A1 (en) * 1996-03-20 1997-09-25 Immunomedics, Inc. Humanization of an anti-carcinoembryonic antigen anti-idiotype antibody and use as a tumor vaccine and for targeting applications
WO2005067980A2 (en) * 2004-01-12 2005-07-28 Pointilliste, Inc. Design of therapeutics and therapeutics
GB0404187D0 (en) * 2004-02-25 2004-03-31 Biotransformations Ltd Binding agents
EP2190861A4 (en) * 2007-08-22 2011-03-30 Univ California ACTIVE BINDING POLYPEPTIDES AND METHOD FOR THEIR IDENTIFICATION AND USE
EP3543256A1 (en) * 2009-01-12 2019-09-25 Cytomx Therapeutics Inc. Modified antibody compositions, methods of making and using thereof
US11492383B2 (en) * 2011-06-24 2022-11-08 Stephen D. Gillies Light chain immunoglobulin fusion proteins and methods of use thereof
GB201203442D0 (en) * 2012-02-28 2012-04-11 Univ Birmingham Immunotherapeutic molecules and uses
CA2913052A1 (en) * 2013-05-24 2014-11-27 Board Of Regents, The University Of Texas System Chimeric antigen receptor-targeting monoclonal antibodies
DK3105317T3 (en) * 2014-02-14 2019-01-14 Cellectis Immunotherapy cells that are genetically engineered to target antigen on both immune cells and pathological cells
CA2955947A1 (en) * 2014-07-25 2016-01-28 Cytomx Therapeutics, Inc. Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
CN107709356A (zh) * 2015-06-26 2018-02-16 南加利福尼亚大学 用于肿瘤特异性活化的掩蔽嵌合抗原受体t细胞
WO2017075537A1 (en) * 2015-10-30 2017-05-04 Aleta Biotherapeutics Inc. Compositions and methods for treatment of cancer
WO2017162587A1 (en) * 2016-03-22 2017-09-28 F. Hoffmann-La Roche Ag Protease-activated t cell bispecific molecules
WO2017177337A1 (en) * 2016-04-15 2017-10-19 Zymeworks Inc. Multi-specific antigen-binding constructs targeting immunotherapeutics

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