JP2018512597A - 突然変異体スムースンド及びその使用方法 - Google Patents

突然変異体スムースンド及びその使用方法 Download PDF

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JP2018512597A
JP2018512597A JP2017559776A JP2017559776A JP2018512597A JP 2018512597 A JP2018512597 A JP 2018512597A JP 2017559776 A JP2017559776 A JP 2017559776A JP 2017559776 A JP2017559776 A JP 2017559776A JP 2018512597 A JP2018512597 A JP 2018512597A
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amino acid
antibody
smo
protein
cell
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ソバージュ フレデリック ジェイ． ド
ソバージュ フレデリック ジェイ． ド
ロバート エル． ヨーチ
ロバート エル． ヨーチ
ヘリット イェー．ペー． ダイクラーフ
ヘリット イェー．ペー． ダイクラーフ
ヘイリー シャーペ
ヘイリー シャーペ
ニコル バセー−セガン
ニコル バセー−セガン
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Universite Paris Diderot Paris 7
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
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JP2017559776A 2015-02-04 2016-02-04 突然変異体スムースンド及びその使用方法 Pending JP2018512597A (ja)

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US201562112074P 2015-02-04 2015-02-04
US62/112,074 2015-02-04
PCT/US2016/016614 WO2016126972A1 (en) 2015-02-04 2016-02-04 Mutant smoothened and methods of using the same

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JP2018512597A true JP2018512597A (ja) 2018-05-17
JP2018512597A5 JP2018512597A5 (https=) 2019-03-14

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US (1) US10330683B2 (https=)
EP (1) EP3253784B1 (https=)
JP (1) JP2018512597A (https=)
CN (1) CN107636170A (https=)
AU (1) AU2016215227A1 (https=)
CA (1) CA2975875A1 (https=)
HK (1) HK1244512A1 (https=)
WO (1) WO2016126972A1 (https=)

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CN108645830A (zh) * 2018-05-15 2018-10-12 华中科技大学鄂州工业技术研究院 一种纳米荧光探针联合蛋白芯片寻找药物作用靶点的方法
CN110174363A (zh) * 2019-01-09 2019-08-27 北京九强生物技术股份有限公司 6-磷酸葡萄糖脱氢酶突变体及其在制备检测试剂中的用途
CN109887553B (zh) * 2019-01-29 2021-01-26 杭州纽安津生物科技有限公司 针对肿瘤靶向药物耐药位点的多肽疫苗及其设计方法
WO2020165370A1 (en) * 2019-02-13 2020-08-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
CN111658628B (zh) * 2019-03-08 2022-03-01 中国科学院动物研究所 Gli2抑制剂的用途以及抑制gli2的化合物的筛选方法
CN114910643B (zh) * 2021-02-10 2023-08-11 广东菲鹏生物有限公司 一种鉴别结合突变型抗原的抗体的方法及试剂
CN115247191B (zh) * 2021-11-30 2025-03-28 南京启真基因工程有限公司 基因编辑系统及其在构建双基因突变的痣样基底细胞癌综合征猪核移植供体细胞中的应用
CN114464246B (zh) * 2022-01-19 2023-05-30 华中科技大学同济医学院附属协和医院 基于CovMutt框架检测与遗传性增加相关的突变的方法
CN115327134B (zh) * 2022-08-26 2025-03-18 复旦大学附属中山医院 Erbb2 s310f突变的抗体在制备诊断检测胆囊癌中的应用

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US20120039893A1 (en) * 2010-10-05 2012-02-16 Genentech, Inc. Mutant smoothened and methods of using the same
JP2013503644A (ja) * 2009-09-02 2013-02-04 ジェネンテック， インコーポレイテッド 突然変異体ｓｍｏｏｔｈｅｎｅｄおよびその使用方法

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