JP2018508519A5 - - Google Patents

Info

Publication number

JP2018508519A5

JP2018508519A5 JP2017546102A JP2017546102A JP2018508519A5 JP 2018508519 A5 JP2018508519 A5 JP 2018508519A5 JP 2017546102 A JP2017546102 A JP 2017546102A JP 2017546102 A JP2017546102 A JP 2017546102A JP 2018508519 A5 JP2018508519 A5 JP 2018508519A5

Authority

JP

Japan

Prior art keywords

cone

composition

amino acids

seq

item

Prior art date

2016-03-02

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 241000702421 Dependoparvovirus Species 0.000 claims description 13
• 108090000765 processed proteins & peptides Proteins 0.000 claims description 12
• 108090000565 Capsid Proteins Proteins 0.000 claims description 11
• 102100023321 Ceruloplasmin Human genes 0.000 claims description 11
• 102000040430 polynucleotide Human genes 0.000 claims description 11
• 108091033319 polynucleotide Proteins 0.000 claims description 11
• 239000002157 polynucleotide Substances 0.000 claims description 11
• 208000017442 Retinal disease Diseases 0.000 claims description 9
• 208000034461 Progressive cone dystrophy Diseases 0.000 claims description 6
• 201000008615 cone dystrophy Diseases 0.000 claims description 6
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 6
• 208000035475 disorder Diseases 0.000 claims description 6
• 241000288906 Primates Species 0.000 claims description 4
• 208000007014 Retinitis pigmentosa Diseases 0.000 claims description 4
• 206010064930 age-related macular degeneration Diseases 0.000 claims description 4
• 125000003275 alpha amino acid group Chemical group 0.000 claims description 4
• 208000002780 macular degeneration Diseases 0.000 claims description 4
• 230000001225 therapeutic effect Effects 0.000 claims description 4
• 108090000623 proteins and genes Proteins 0.000 claims description 3
• 208000037663 Best vitelliform macular dystrophy Diseases 0.000 claims description 2
• 208000021089 Coats disease Diseases 0.000 claims description 2
• 208000006992 Color Vision Defects Diseases 0.000 claims description 2
• 206010012689 Diabetic retinopathy Diseases 0.000 claims description 2
• 208000028506 Familial Exudative Vitreoretinopathies Diseases 0.000 claims description 2
• 208000008069 Geographic Atrophy Diseases 0.000 claims description 2
• 208000035719 Maculopathy Diseases 0.000 claims description 2
• 208000008709 Retinal Telangiectasis Diseases 0.000 claims description 2
• 206010038923 Retinopathy Diseases 0.000 claims description 2
• 208000027073 Stargardt disease Diseases 0.000 claims description 2
• 206010043189 Telangiectasia Diseases 0.000 claims description 2
• 208000000208 Wet Macular Degeneration Diseases 0.000 claims description 2
• 201000007254 color blindness Diseases 0.000 claims description 2
• 201000006902 exudative vitreoretinopathy Diseases 0.000 claims description 2
• 201000006321 fundus dystrophy Diseases 0.000 claims description 2
• 208000014188 hereditary optic neuropathy Diseases 0.000 claims description 2
• 230000002207 retinal effect Effects 0.000 claims description 2
• 208000032253 retinal ischemia Diseases 0.000 claims description 2
• 208000004644 retinal vein occlusion Diseases 0.000 claims description 2
• 230000009919 sequestration Effects 0.000 claims description 2
• 230000000392 somatic effect Effects 0.000 claims description 2
• 208000009056 telangiectasis Diseases 0.000 claims description 2
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• 208000020938 vitelliform macular dystrophy 2 Diseases 0.000 claims description 2
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• 150000001413 amino acids Chemical class 0.000 description 83
• 238000000034 method Methods 0.000 description 38
• 241000702423 Adeno-associated virus - 2 Species 0.000 description 9
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• 241001655883 Adeno-associated virus - 1 Species 0.000 description 3
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