ES2186340T3 - Utilizacion de polipeptidos fgf-5 para la prevencion de la muerte de neuronas retinales y para el tratamiento de enfermedades oculares. - Google Patents
Utilizacion de polipeptidos fgf-5 para la prevencion de la muerte de neuronas retinales y para el tratamiento de enfermedades oculares.Info
- Publication number
- ES2186340T3 ES2186340T3 ES99912439T ES99912439T ES2186340T3 ES 2186340 T3 ES2186340 T3 ES 2186340T3 ES 99912439 T ES99912439 T ES 99912439T ES 99912439 T ES99912439 T ES 99912439T ES 2186340 T3 ES2186340 T3 ES 2186340T3
- Authority
- ES
- Spain
- Prior art keywords
- retinal
- retinopathies
- polypeptides
- fgf
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Utilización de un polipéptido activo de FGF-5 en la preparación de un medicamento para retrasar, prevenir o rescatar las células de la retina de la lesión o de la muerte celular.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4138398A | 1998-03-12 | 1998-03-12 | |
US09/240,952 US6331523B1 (en) | 1998-03-12 | 1999-01-29 | Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2186340T3 true ES2186340T3 (es) | 2003-05-01 |
Family
ID=26718088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99912439T Expired - Lifetime ES2186340T3 (es) | 1998-03-12 | 1999-03-10 | Utilizacion de polipeptidos fgf-5 para la prevencion de la muerte de neuronas retinales y para el tratamiento de enfermedades oculares. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1061943B1 (es) |
JP (2) | JP3764047B2 (es) |
AT (1) | ATE226444T1 (es) |
AU (1) | AU754380B2 (es) |
CA (1) | CA2322380C (es) |
DE (1) | DE69903612T2 (es) |
ES (1) | ES2186340T3 (es) |
IL (1) | IL138033A0 (es) |
WO (1) | WO1999045952A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
JP2002539176A (ja) * | 1999-03-15 | 2002-11-19 | カイロン コーポレイション | 眼の疾患を処置または予防するための組換え遺伝子送達ベクターの使用 |
AU774958B2 (en) * | 1999-10-02 | 2004-07-15 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Fibroblast growth factor-5 (FGF-5) is a tumor associated T-cell antigen |
EP2305308A1 (en) * | 2003-04-18 | 2011-04-06 | Advanced Medicine Research Institute | Remedies for diseases to be applied to eye |
JP2008064459A (ja) * | 2004-12-24 | 2008-03-21 | Univ Kurume | 色素上皮由来因子の定量法 |
US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
MX338067B (es) | 2008-07-16 | 2016-04-01 | Inst Research In Biomedicine | Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos. |
TWI775096B (zh) | 2012-05-15 | 2022-08-21 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
JP6628252B2 (ja) * | 2014-02-28 | 2020-01-08 | 国立大学法人京都大学 | 虚血性眼疾患の処置用の医薬組成物 |
SG10201810150UA (en) | 2014-03-17 | 2018-12-28 | Adverum Biotechnologies Inc | Compositions and methods for enhanced gene expression in cone cells |
WO2016141078A1 (en) | 2015-03-02 | 2016-09-09 | Avalanche Biotechnologies, Inc. | Compositions and methods for intravitreal delivery of polynucleotides to retinal cones |
GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA941729B (en) * | 1993-03-12 | 1994-10-13 | Max Planck Gesellschaft | Treatment of motor neuron diseases with fibroblast growth factor-5 (fgf-5). |
JPH09510352A (ja) * | 1994-03-15 | 1997-10-21 | プリズム ファーマシューティカルズ,インコーポレイティド | 遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子 |
US5629284A (en) * | 1995-07-24 | 1997-05-13 | Meiji Milk Products Co., Ltd. | Method for treating retinal diseases |
IL129379A (en) * | 1996-10-16 | 2008-12-29 | Zymogenetics Inc | Fibroblast growth factor homologues |
-
1999
- 1999-03-10 AT AT99912439T patent/ATE226444T1/de not_active IP Right Cessation
- 1999-03-10 EP EP99912439A patent/EP1061943B1/en not_active Expired - Lifetime
- 1999-03-10 CA CA002322380A patent/CA2322380C/en not_active Expired - Lifetime
- 1999-03-10 JP JP2000535365A patent/JP3764047B2/ja not_active Expired - Lifetime
- 1999-03-10 IL IL13803399A patent/IL138033A0/xx active IP Right Grant
- 1999-03-10 WO PCT/US1999/005375 patent/WO1999045952A2/en active IP Right Grant
- 1999-03-10 DE DE69903612T patent/DE69903612T2/de not_active Expired - Lifetime
- 1999-03-10 ES ES99912439T patent/ES2186340T3/es not_active Expired - Lifetime
- 1999-03-10 AU AU30813/99A patent/AU754380B2/en not_active Expired
-
2005
- 2005-10-04 JP JP2005290896A patent/JP2006089489A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69903612D1 (de) | 2002-11-28 |
AU3081399A (en) | 1999-09-27 |
JP2006089489A (ja) | 2006-04-06 |
IL138033A0 (en) | 2001-10-31 |
CA2322380A1 (en) | 1999-09-16 |
EP1061943B1 (en) | 2002-10-23 |
JP3764047B2 (ja) | 2006-04-05 |
ATE226444T1 (de) | 2002-11-15 |
CA2322380C (en) | 2008-10-14 |
WO1999045952A3 (en) | 2000-11-23 |
JP2002526381A (ja) | 2002-08-20 |
WO1999045952A2 (en) | 1999-09-16 |
DE69903612T2 (de) | 2003-07-10 |
AU754380B2 (en) | 2002-11-14 |
EP1061943A1 (en) | 2000-12-27 |
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