ATE226444T1 - Verwendung von fgf-5 polypetiden zur vorbeugung des absterbens retinaler neuronen und behandlung okularer krankheiten - Google Patents

Verwendung von fgf-5 polypetiden zur vorbeugung des absterbens retinaler neuronen und behandlung okularer krankheiten

Info

Publication number
ATE226444T1
ATE226444T1 AT99912439T AT99912439T ATE226444T1 AT E226444 T1 ATE226444 T1 AT E226444T1 AT 99912439 T AT99912439 T AT 99912439T AT 99912439 T AT99912439 T AT 99912439T AT E226444 T1 ATE226444 T1 AT E226444T1
Authority
AT
Austria
Prior art keywords
retinal
retinopathies
fgf
cells
retinopathy
Prior art date
Application number
AT99912439T
Other languages
English (en)
Inventor
Ivar J Kljavin
Fleur Monique La
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/240,952 external-priority patent/US6331523B1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE226444T1 publication Critical patent/ATE226444T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT99912439T 1998-03-12 1999-03-10 Verwendung von fgf-5 polypetiden zur vorbeugung des absterbens retinaler neuronen und behandlung okularer krankheiten ATE226444T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4138398A 1998-03-12 1998-03-12
US09/240,952 US6331523B1 (en) 1998-03-12 1999-01-29 Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5
PCT/US1999/005375 WO1999045952A2 (en) 1998-03-12 1999-03-10 Method of preventing the death of retinal neurons and treating ocular diseases

Publications (1)

Publication Number Publication Date
ATE226444T1 true ATE226444T1 (de) 2002-11-15

Family

ID=26718088

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99912439T ATE226444T1 (de) 1998-03-12 1999-03-10 Verwendung von fgf-5 polypetiden zur vorbeugung des absterbens retinaler neuronen und behandlung okularer krankheiten

Country Status (9)

Country Link
EP (1) EP1061943B1 (de)
JP (2) JP3764047B2 (de)
AT (1) ATE226444T1 (de)
AU (1) AU754380B2 (de)
CA (1) CA2322380C (de)
DE (1) DE69903612T2 (de)
ES (1) ES2186340T3 (de)
IL (1) IL138033A0 (de)
WO (1) WO1999045952A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
JP2002539176A (ja) * 1999-03-15 2002-11-19 カイロン コーポレイション 眼の疾患を処置または予防するための組換え遺伝子送達ベクターの使用
AU774958B2 (en) * 1999-10-02 2004-07-15 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Fibroblast growth factor-5 (FGF-5) is a tumor associated T-cell antigen
EP2305308A1 (de) * 2003-04-18 2011-04-06 Advanced Medicine Research Institute Mittel zur Behandlung von Krankheiten zur Aufbringung auf das Auge
JP2008064459A (ja) * 2004-12-24 2008-03-21 Univ Kurume 色素上皮由来因子の定量法
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
MX338067B (es) 2008-07-16 2016-04-01 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos.
TWI775096B (zh) 2012-05-15 2022-08-21 澳大利亞商艾佛蘭屈澳洲私營有限公司 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
JP6628252B2 (ja) * 2014-02-28 2020-01-08 国立大学法人京都大学 虚血性眼疾患の処置用の医薬組成物
SG10201810150UA (en) 2014-03-17 2018-12-28 Adverum Biotechnologies Inc Compositions and methods for enhanced gene expression in cone cells
WO2016141078A1 (en) 2015-03-02 2016-09-09 Avalanche Biotechnologies, Inc. Compositions and methods for intravitreal delivery of polynucleotides to retinal cones
GB2545763A (en) 2015-12-23 2017-06-28 Adverum Biotechnologies Inc Mutant viral capsid libraries and related systems and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA941729B (en) * 1993-03-12 1994-10-13 Max Planck Gesellschaft Treatment of motor neuron diseases with fibroblast growth factor-5 (fgf-5).
JPH09510352A (ja) * 1994-03-15 1997-10-21 プリズム ファーマシューティカルズ，インコーポレイティド 遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子
US5629284A (en) * 1995-07-24 1997-05-13 Meiji Milk Products Co., Ltd. Method for treating retinal diseases
IL129379A (en) * 1996-10-16 2008-12-29 Zymogenetics Inc Fibroblast growth factor homologues

Also Published As

Publication number Publication date
DE69903612D1 (de) 2002-11-28
AU3081399A (en) 1999-09-27
JP2006089489A (ja) 2006-04-06
IL138033A0 (en) 2001-10-31
CA2322380A1 (en) 1999-09-16
EP1061943B1 (de) 2002-10-23
JP3764047B2 (ja) 2006-04-05
CA2322380C (en) 2008-10-14
WO1999045952A3 (en) 2000-11-23
JP2002526381A (ja) 2002-08-20
ES2186340T3 (es) 2003-05-01
WO1999045952A2 (en) 1999-09-16
DE69903612T2 (de) 2003-07-10
AU754380B2 (en) 2002-11-14
EP1061943A1 (de) 2000-12-27

Similar Documents

Publication Publication Date Title
WO2001009327A3 (en) Method of preventing the injury or death of retinal cells and treating ocular diseases
ATE226444T1 (de) Verwendung von fgf-5 polypetiden zur vorbeugung des absterbens retinaler neuronen und behandlung okularer krankheiten
NO982275D0 (no) FremgangsmÕter for behandling av fotoreseptorer under anvendelse av proteinprodukt av gliacellelinjeavledet neurotrof faktor (GDNF)
Valiente-Soriano et al. BDNF rescues RGCs but not intrinsically photosensitive RGCs in ocular hypertensive albino rat retinas
Chang et al. Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure
Guillery Neural abnormalities of albinos
Drucker et al. Pathogenesis of post-traumatic sympathetic dystrophy
Tsutsumi-Miyahara et al. The relative contributions of each subset of ocular infiltrated cells in experimental choroidal neovascularisation
He et al. Gene expression signatures in tree shrew choroid in response to three myopiagenic conditions
Nishihara et al. Surface scattering in implanted hydrophobic intraocular lenses
JP2004262947A (ja) 網膜の色素沈着された上皮由来の神経栄養性因子
WO2000053760A3 (en) Method of preventing the death of retinal neurons and treating ocular diseases
Tandon et al. Amniotic membrane grafting for conjunctival and lid surface disease in the acute phase of toxic epidermal necrolysis
AU5135098A (en) Use of nerve growth factor for the storage, culture or treatment of cornea
Abe et al. Lens epithelial changes and mutated gene expression in patients with myotonic dystrophy
ITRM20100100A1 (it) Composizione farmaceutica a base di glicirrizina e polimero eg56 per la preparazione di prodotti ad azione flogolitica.
JPS6284025A (ja) 繊維芽細胞増殖促進作用を有する胎盤由来蛋白加水分解物
EP0083261B1 (de) Therapeutische Zusammensetzung für die Behandlung von Schwierigkeiten des Anpassungsvermögens des Auges
Copello et al. Ozone therapy in patients with retinitis pigmentosa
EP1059931B1 (de) Verwendung von cd137 zur förderung der proliferation peripherer monocyten
Bernhard et al. Chronic ulcerating acyclovir-resistant varicella zoster lesions in an AIDS patient
Travers et al. A controlled trial of adenine arabinoside and trifluorothymidine in herpetic keratitis
Møller et al. Early treatment of granular dystrophy (Groenouw type I)
Sambhav et al. Necrotizing scleritis in a case of Vogt-Koyanagi-Harada disease
Srinivas et al. Haridra (curcuma longa) and its effect on abhisayanda (conjunctivitis)

Legal Events

Date Code Title Description
REZ Deleted due to withdrawal