JP2018503668A5 - - Google Patents

Download PDF

Info

Publication number
JP2018503668A5
JP2018503668A5 JP2017540549A JP2017540549A JP2018503668A5 JP 2018503668 A5 JP2018503668 A5 JP 2018503668A5 JP 2017540549 A JP2017540549 A JP 2017540549A JP 2017540549 A JP2017540549 A JP 2017540549A JP 2018503668 A5 JP2018503668 A5 JP 2018503668A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
phe
composition according
lys
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017540549A
Other languages
English (en)
Japanese (ja)
Other versions
JP6613312B2 (ja
JP2018503668A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/055305 external-priority patent/WO2016061087A1/en
Publication of JP2018503668A publication Critical patent/JP2018503668A/ja
Publication of JP2018503668A5 publication Critical patent/JP2018503668A5/ja
Application granted granted Critical
Publication of JP6613312B2 publication Critical patent/JP6613312B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017540549A 2014-10-14 2015-10-13 膵臓癌を処置するためのペプチドをベースとする方法 Expired - Fee Related JP6613312B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462063909P 2014-10-14 2014-10-14
US62/063,909 2014-10-14
PCT/US2015/055305 WO2016061087A1 (en) 2014-10-14 2015-10-13 Peptide-based methods for treating pancreatic cancer

Publications (3)

Publication Number Publication Date
JP2018503668A JP2018503668A (ja) 2018-02-08
JP2018503668A5 true JP2018503668A5 (https=) 2018-11-22
JP6613312B2 JP6613312B2 (ja) 2019-11-27

Family

ID=54365375

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017540549A Expired - Fee Related JP6613312B2 (ja) 2014-10-14 2015-10-13 膵臓癌を処置するためのペプチドをベースとする方法
JP2017540551A Active JP7023709B2 (ja) 2014-10-14 2015-10-13 抗炎症特性を有するペプチド
JP2020118752A Pending JP2020180149A (ja) 2014-10-14 2020-07-09 抗炎症性組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017540551A Active JP7023709B2 (ja) 2014-10-14 2015-10-13 抗炎症特性を有するペプチド
JP2020118752A Pending JP2020180149A (ja) 2014-10-14 2020-07-09 抗炎症性組成物

Country Status (10)

Country Link
US (5) US10016480B2 (https=)
EP (2) EP3206704B1 (https=)
JP (3) JP6613312B2 (https=)
KR (3) KR20230004907A (https=)
CN (2) CN107106638A (https=)
AU (2) AU2015333728B2 (https=)
BR (1) BR112017007543A2 (https=)
CA (2) CA2964361A1 (https=)
WO (2) WO2016061133A1 (https=)
ZA (1) ZA201702537B (https=)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4282419A1 (en) 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
US10016480B2 (en) * 2014-10-14 2018-07-10 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Peptide-based methods for treating pancreatic cancer
WO2017149012A1 (en) * 2016-03-02 2017-09-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Peptides and uses thereof for reducing cd95-mediated cell motility
KR20180117227A (ko) * 2016-03-24 2018-10-26 난트셀, 인크. 네오에피토프 제시를 위한 시퀀스들 및 시퀀스 배열들
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
CA3023802C (en) * 2016-05-10 2025-02-04 Inserm (Institut De La Sante Et De La Recherche Medicale) ACTIVATING AGENTS OF THE DIFFERENTIATION CLUSTER 47 FOR USE IN THE TREATMENT OF INFLAMMATION
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
EP4101447A1 (en) 2016-06-30 2022-12-14 Nant Holdings IP, LLC Nant cancer vaccine
CN106432014B (zh) * 2016-09-05 2019-08-16 中国医学科学院放射医学研究所 胺基硫醇类化合物及其制备方法和其在辐射防护中的应用
US10799555B2 (en) 2016-09-15 2020-10-13 Leidos, Inc. PD-1 peptide inhibitors
WO2018086562A1 (en) * 2016-11-09 2018-05-17 Shen Tang Long Method for treatment or prevention of cancer
US20190358263A1 (en) * 2016-12-07 2019-11-28 Oslo Universitetssykehus Hf Compositions and Methods for Cell Therapy
US11649288B2 (en) 2017-02-07 2023-05-16 Seattle Children's Hospital Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
EP3612210A4 (en) 2017-04-19 2021-01-27 Board Of Regents, The University Of Texas System MANIPULATED ANTIGEN RECEPTORS EXPRESSING IMMUNE CELLS
US11779637B2 (en) 2017-04-24 2023-10-10 Nantcell, Inc. Targeted neoepitope vectors and methods therefor
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
WO2018218137A1 (en) 2017-05-25 2018-11-29 Leidos, Inc. Pd-1 and ctla-4 dual inhibitor peptides
WO2019067984A2 (en) 2017-09-29 2019-04-04 Sanford Burnham Prebys Medical Discovery Institute COMPOSITIONS TARGETING TUMOR ASSOCIATED MACROPHAGES AND METHODS OF USING THE SAME
CN109745324B (zh) * 2017-11-06 2026-02-06 中国科学院上海营养与健康研究所 非经典NF-kB通路的小分子抑制剂及其应用
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
US12312416B2 (en) 2018-02-06 2025-05-27 Seattle Children's Hospital Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors
US12473336B2 (en) 2018-02-21 2025-11-18 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses thereof
AU2019225174B2 (en) 2018-02-23 2025-11-20 Endocyte, Inc. Sequencing method for CAR T cell therapy
DK3758732T3 (da) * 2018-02-27 2024-10-07 Leidos Inc PD-1-peptidinhibitorer
US11823773B2 (en) 2018-04-13 2023-11-21 Nant Holdings Ip, Llc Nant cancer vaccine strategies
EP3810278A1 (en) * 2018-06-20 2021-04-28 Universidade de Coimbra (3s)- and (3r)-6,7-bis(hydroxymethyl)-1h,3h-pyrrolo[1,2-c]thiazoles as p53 activators
WO2020037043A1 (en) * 2018-08-15 2020-02-20 The Regents Of The University Of California Il-10 inhibition for vaccines and immunotherapy
EP3844500A4 (en) 2018-08-27 2022-05-11 NantBio, Inc. RP182 COMPOSITIONS AND METHODS
US10413584B1 (en) * 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US20220143130A1 (en) * 2018-08-29 2022-05-12 Riptide Bioscience, Inc. Peptides Having Immunomodulatory Properties
CA3110618A1 (en) * 2018-08-29 2020-03-05 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
CN110960679A (zh) * 2018-09-28 2020-04-07 江苏康缘药业股份有限公司 一种抗肿瘤的药物组合物及其应用
US20220053773A1 (en) * 2018-10-01 2022-02-24 Innate Immunity LLC Compositions and methods for the treatment of pathogenic infections in plants
US20200102356A1 (en) * 2018-10-01 2020-04-02 NMC Inc. Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
US10548944B1 (en) 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
CN113710229B (zh) 2019-02-25 2026-01-06 芝加哥大学 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物
KR20210151945A (ko) 2019-04-12 2021-12-14 립타이드 바이오사이언스, 인코포레이티드 대식세포 활성을 조정하기 위한 방법
US12221622B2 (en) * 2019-05-10 2025-02-11 The Regents Of The University Of California Modified pluripotent cells
WO2020237050A1 (en) 2019-05-22 2020-11-26 Leidos, Inc. Lag3 binding peptides
EP3990000A1 (en) * 2019-06-28 2022-05-04 Nantcell, Inc. Pharmaceutical compositions to enhance phagocytosis without inflammation
CA3165339A1 (en) 2019-12-19 2021-06-24 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Cd206 modulators their use and methods for preparation
CN111116713B (zh) * 2020-01-07 2023-06-23 郑州大学 Sirpa蛋白亲和环肽及其应用
CN115210252A (zh) 2020-02-04 2022-10-18 西雅图儿童医院(Dba西雅图儿童研究所) 抗二硝基苯酚的嵌合抗原受体
AU2021246017A1 (en) * 2020-03-31 2022-11-10 Innate Immunity LLC Recombinant peptide to treat fire blight
CA3185657A1 (en) 2020-06-04 2021-12-09 Leidos, Inc. Immunomodulatory compounds
WO2022034523A1 (en) 2020-08-13 2022-02-17 Immunitybio, Inc. Phagocytosis-inducing compounds and methods of use
EP4225444A1 (en) 2020-10-12 2023-08-16 Leidos, Inc. Immunomodulatory peptides
WO2023277514A1 (ko) * 2021-06-28 2023-01-05 고려대학교 산학협력단 항암 활성을 갖는 펩타이드 및 이의 용도
CN115607674B (zh) * 2021-07-15 2023-09-19 深圳开悦生命科技有限公司 Rna解旋酶dhx33抑制剂在制备用于治疗胰腺癌的药物中的应用
WO2023080578A1 (ko) * 2021-11-05 2023-05-11 주식회사 레메디 상처 치료 및 항염증 활성을 가지는 펩타이드 및 이의 용도
WO2023097111A2 (en) * 2021-11-29 2023-06-01 Riptide Bioscience, Inc. Methods and compositions for treating calcinosis associated conditions
EP4277645A1 (en) * 2021-12-16 2023-11-22 Ramakrishna Reddy Isanaka A stable anti-angiogenic and anti-inflammatory pharmaceutical formulation and pharmaceutical combination for treatment and prevention of psoriasis
KR102920640B1 (ko) 2022-03-11 2026-01-29 국립순천대학교산학협력단 항진균 활성을 나타내는 펩타이드 및 이를 유효성분으로 포함하는 항진균용 조성물
WO2024102993A1 (en) * 2022-11-10 2024-05-16 Research Foundation Of The City University Of New York Cationically-enframed high density aromatic peptides
CN115838395A (zh) * 2022-11-15 2023-03-24 西北农林科技大学 具有可溶性环氧化物水解酶抑制作用的活性肽及其应用
CN116768970A (zh) * 2023-05-19 2023-09-19 重庆师范大学 抗氧化多肽、制备方法及其应用
CN117143183B (zh) * 2023-08-25 2024-08-16 广州益养生物科技有限公司 一种三肽、三肽盐或衍生物及其应用
WO2025093952A1 (en) * 2023-10-30 2025-05-08 Ramakrishna Reddy Isanaka Peptide with anti-inflammatory and anti-microbial activity
WO2025255373A2 (en) * 2024-06-05 2025-12-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Fatty acid and cyclized derivatives of the immunomodulatory peptide rp-182 with improved anti-tumor activity, compositions, and methods of use thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
WO1989000194A1 (en) 1987-07-06 1989-01-12 Louisiana State University Agricultural And Mechan Inhibition of eucaryotic pathogens and neoplasms and stimulation of fibroblasts and lymphocytes with lytic peptides
CA2032527C (en) 1989-04-10 2002-07-02 Jesse M. Jaynes Lytic peptides: their use in the treatment of microbial infections, cancer and in the promotion of growth
AU2514592A (en) * 1991-08-21 1993-03-16 Board Of Regents, The University Of Texas System Methods and compositions for modulating g protein action
US5955573A (en) * 1993-06-04 1999-09-21 Demegen, Inc. Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
WO1995013085A1 (en) * 1993-11-08 1995-05-18 Demeter Biotechnologies Ltd. Methylated lysine-rich lytic peptides and method of making same by reductive alkylation
IL114697A0 (en) * 1994-07-22 1995-11-27 Demeter Biotech Ltd Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use
JP2001501620A (ja) 1996-10-04 2001-02-06 デメジェン インコーポレイテッド 免疫不全ウイルス感染の治療方法
DE19711831C2 (de) 1997-03-21 2000-07-13 Daimler Chrysler Ag Schmelzinfiltrierte faserverstärkte Verbundkeramik und Verfahren zur Herstellung einer solchen
US6635740B1 (en) 1997-03-27 2003-10-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Ligand/lytic peptide compositions and methods of use
AU6587998A (en) * 1997-03-27 1998-10-20 Demeter Biotechnologies, Ltd. Ligand/lytic peptide compositions and methods of use
IL147970A0 (en) * 1999-08-09 2002-09-12 Tripep Ab Pharmaceutical compositions containing tripeptides
CA2441562C (en) 2001-03-28 2013-05-14 Helix Biomedix, Inc. Short bioactive peptides and methods for their use
US7091185B2 (en) 2003-02-24 2006-08-15 Dow Global Technologies Inc. Periodic antimicrobial peptides
GB0326393D0 (en) 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
US7288622B1 (en) * 2006-09-19 2007-10-30 Issar Pharmaceuticals Pvt Ltd Composition for treatment of burns and wounds
US7803755B2 (en) * 2006-12-21 2010-09-28 Jesse Jaynes Molecules for the treatment and prevention of fungal diseases
TWI436775B (zh) * 2007-08-24 2014-05-11 Oncotherapy Science Inc 以抗原胜肽合併化療藥劑治療胰臟癌
CN101485885B (zh) * 2009-01-09 2012-06-27 中国科学院广州生物医药与健康研究院 蛋白磷酸酯酶PPM1E作为疾病的治疗靶标及其应用和siRNA
GB0916576D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
US20120270770A1 (en) * 2010-08-03 2012-10-25 Jesse Michael Jaynes Anti-angiogenic peptides and their uses
WO2012050892A2 (en) * 2010-09-29 2012-04-19 Esperance Pharmaceuticals, Inc. Methods for stimulating, increasing or enhancing killing of a cell that expresses luteinizing hormone releasing hormone (lhrh) receptors
US8734775B2 (en) 2011-08-26 2014-05-27 University Of Pittsburgh Chemokine derived peptides that bind with chemokine receptor CXCR3 and uses for chronic wound and angiogenesis inhibition treatments
US9487560B2 (en) 2013-05-02 2016-11-08 ISSAR Pharmaceuticals Ltd Angiogenic active lytic peptides
US10016480B2 (en) * 2014-10-14 2018-07-10 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Peptide-based methods for treating pancreatic cancer
US9737584B2 (en) * 2015-08-11 2017-08-22 Issar Pharmaceuticals Composition for the treatment of burns, diabetic wounds, other types of wounds and subsequently greatly reduced scarring

Similar Documents

Publication Publication Date Title
JP2018503668A5 (https=)
FI3430027T3 (fi) Peptidi käytettäväksi ei-pienisoluisen keuhkosyövän ja pienisoluisen keuhkosyövän hoidossa
PH12020552179A1 (en) Bicyclic peptide ligands specific for nectin-4
BR112021022315A2 (pt) Ligantes de peptídeo bicíclicos específicos para ox40
JP2018521983A5 (https=)
JP2016527286A5 (https=)
PH12020550929A1 (en) Bicyclic peptide ligands specific for epha2
MX2017004592A (es) Formulaciones farmaceuticas para la administracion oral de farmacos peptidicos o proteinicos.
JP2017528419A5 (https=)
JP2018523703A5 (https=)
JP2017523781A5 (https=)
TW201613958A (en) MIC-1 fusion proteins and uses thereof
JP2022514687A5 (https=)
JP2016502515A5 (https=)
NZ731185A (en) Bicyclic peptide ligands specific for mt1-mmp
HRP20192174T1 (hr) Kombinirani farmaceutski pripravak
JP2015510393A5 (https=)
JP2017521486A5 (https=)
JP2017503014A5 (https=)
WO2017009843A3 (en) Compositions, articles of manufacture and methods for treating cancer
JP2014526881A5 (https=)
JP2016506413A5 (https=)
MX2020006822A (es) Proteinas de fusion de anticuerpo de un solo dominio-citosina desaminasa.
JP2019533722A5 (https=)
RU2017114673A (ru) Слитый белок, наночастица, состоящая из множества мономеров указанного слитого белка, и их применение