|
CA2831144A1
(en)
|
2011-03-23 |
2012-09-27 |
Pioneer Hi-Bred International, Inc. |
Methods for producing a complex transgenic trait locus
|
|
US10323236B2
(en)
|
2011-07-22 |
2019-06-18 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
CN112301024A
(zh)
|
2013-03-15 |
2021-02-02 |
通用医疗公司 |
使用RNA引导的FokI核酸酶(RFN)提高RNA引导的基因组编辑的特异性
|
|
US10760064B2
(en)
|
2013-03-15 |
2020-09-01 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
DK3456831T3
(da)
|
2013-04-16 |
2021-09-06 |
Regeneron Pharma |
Målrettet modifikation af rottegenom
|
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
|
CN120574876A
(zh)
|
2013-08-22 |
2025-09-02 |
纳幕尔杜邦公司 |
使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
KR102170502B1
(ko)
|
2013-12-11 |
2020-10-28 |
리제너론 파마슈티칼스 인코포레이티드 |
게놈의 표적화된 변형을 위한 방법 및 조성물
|
|
US20150165054A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting caspase-9 point mutations
|
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
|
MX2017002930A
(es)
|
2014-09-12 |
2017-06-06 |
Du Pont |
Generacion de sitios de integracion especifica de sitio para loci de rasgos complejos en maiz y soja, y metodos de uso.
|
|
AU2015330699B2
(en)
|
2014-10-10 |
2021-12-02 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
|
GB201418965D0
(https=)
|
2014-10-24 |
2014-12-10 |
Ospedale San Raffaele And Fond Telethon |
|
|
EP4464338A3
(en)
|
2014-11-07 |
2025-02-12 |
Editas Medicine, Inc. |
Systems for improving crispr/cas-mediated genome-editing
|
|
US9650617B2
(en)
|
2015-01-28 |
2017-05-16 |
Pioneer Hi-Bred International. Inc. |
CRISPR hybrid DNA/RNA polynucleotides and methods of use
|
|
BR112017017260A2
(pt)
|
2015-03-27 |
2018-04-17 |
Du Pont |
construções de dna, vetor, célula, plantas, semente, método de expressão de rna e método de modificação de local alvo
|
|
GB201506509D0
(en)
|
2015-04-16 |
2015-06-03 |
Univ Wageningen |
Nuclease-mediated genome editing
|
|
CA2986310A1
(en)
|
2015-05-11 |
2016-11-17 |
Editas Medicine, Inc. |
Optimized crispr/cas9 systems and methods for gene editing in stem cells
|
|
CN108026526B
(zh)
|
2015-06-09 |
2023-05-12 |
爱迪塔斯医药公司 |
用于改善移植的crispr/cas相关方法和组合物
|
|
US20160362667A1
(en)
*
|
2015-06-10 |
2016-12-15 |
Caribou Biosciences, Inc. |
CRISPR-Cas Compositions and Methods
|
|
US9790490B2
(en)
*
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
US10648020B2
(en)
|
2015-06-18 |
2020-05-12 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
|
WO2017004261A1
(en)
|
2015-06-29 |
2017-01-05 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and modified single crispr rna and uses thereof
|
|
US11279928B2
(en)
|
2015-06-29 |
2022-03-22 |
Massachusetts Institute Of Technology |
Compositions comprising nucleic acids and methods of using the same
|
|
US9512446B1
(en)
|
2015-08-28 |
2016-12-06 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
US9926546B2
(en)
|
2015-08-28 |
2018-03-27 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
EP3353296B1
(en)
|
2015-09-24 |
2020-11-04 |
Editas Medicine, Inc. |
Use of exonucleases to improve crispr/cas-mediated genome editing
|
|
IL310721B2
(en)
|
2015-10-23 |
2025-11-01 |
Harvard College |
Nucleobase editors and uses thereof
|
|
WO2017070598A1
(en)
|
2015-10-23 |
2017-04-27 |
Caribou Biosciences, Inc. |
Engineered crispr class 2 cross-type nucleic-acid targeting nucleic acids
|
|
CN108473981B
(zh)
*
|
2015-12-04 |
2022-04-12 |
卡里布生物科学公司 |
工程化靶向核酸的核酸
|
|
US11208649B2
(en)
|
2015-12-07 |
2021-12-28 |
Zymergen Inc. |
HTP genomic engineering platform
|
|
BR112018011503A2
(pt)
|
2015-12-07 |
2018-12-04 |
Zymergen Inc |
promotores da corynebacterium glutamicum
|
|
US9988624B2
(en)
|
2015-12-07 |
2018-06-05 |
Zymergen Inc. |
Microbial strain improvement by a HTP genomic engineering platform
|
|
AU2016365720B2
(en)
|
2015-12-07 |
2020-11-26 |
Arc Bio, Llc |
Methods and compositions for the making and using of guide nucleic acids
|
|
WO2017136794A1
(en)
|
2016-02-03 |
2017-08-10 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide rna and its applications
|
|
US9896696B2
(en)
*
|
2016-02-15 |
2018-02-20 |
Benson Hill Biosystems, Inc. |
Compositions and methods for modifying genomes
|
|
US11597924B2
(en)
|
2016-03-25 |
2023-03-07 |
Editas Medicine, Inc. |
Genome editing systems comprising repair-modulating enzyme molecules and methods of their use
|
|
US11236313B2
(en)
|
2016-04-13 |
2022-02-01 |
Editas Medicine, Inc. |
Cas9 fusion molecules, gene editing systems, and methods of use thereof
|
|
KR20260004568A
(ko)
|
2016-04-19 |
2026-01-08 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신규한 crispr 효소 및 시스템
|
|
CN106244591A
(zh)
*
|
2016-08-23 |
2016-12-21 |
苏州吉玛基因股份有限公司 |
修饰crRNA在CRISPR/Cpf1基因编辑系统中的应用
|
|
EP3464594A1
(en)
|
2016-06-01 |
2019-04-10 |
Kws Saat Se |
Hybrid nucleic acid sequences for genome engineering
|
|
US10767175B2
(en)
|
2016-06-08 |
2020-09-08 |
Agilent Technologies, Inc. |
High specificity genome editing using chemically modified guide RNAs
|
|
EP3478845A4
(en)
|
2016-06-30 |
2019-07-31 |
Zymergen, Inc. |
METHOD OF GENERATING A GLUCOSE PERMEASE LIBRARY AND USES THEREOF
|
|
US10544390B2
(en)
|
2016-06-30 |
2020-01-28 |
Zymergen Inc. |
Methods for generating a bacterial hemoglobin library and uses thereof
|
|
WO2018009822A1
(en)
|
2016-07-08 |
2018-01-11 |
Ohio State Innovation Foundation |
Modified nucleic acids, hybrid guide rnas, and uses thereof
|
|
CN110214183A
(zh)
|
2016-08-03 |
2019-09-06 |
哈佛大学的校长及成员们 |
腺苷核碱基编辑器及其用途
|
|
WO2018031683A1
(en)
|
2016-08-09 |
2018-02-15 |
President And Fellows Of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
WO2018031950A1
(en)
|
2016-08-12 |
2018-02-15 |
Caribou Biosciences, Inc. |
Protein engineering methods
|
|
SG11201901306XA
(en)
*
|
2016-08-19 |
2019-03-28 |
Toolgen Inc |
Artificially engineered angiogenesis regulatory system
|
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
CA3034931A1
(en)
|
2016-09-23 |
2018-03-29 |
Board Of Trustees Of Southern Illinois University |
Tuning crispr/cas9 activity with chemically modified nucleotide substitutions
|
|
KR20260019012A
(ko)
|
2016-10-07 |
2026-02-09 |
인티그레이티드 디엔에이 테크놀로지스 아이엔씨. |
S. 피오게네스 cas9 돌연변이 유전자 및 이에 의해 암호화되는 폴리펩티드
|
|
US11242542B2
(en)
|
2016-10-07 |
2022-02-08 |
Integrated Dna Technologies, Inc. |
S. pyogenes Cas9 mutant genes and polypeptides encoded by same
|
|
KR102622411B1
(ko)
|
2016-10-14 |
2024-01-10 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵염기 에디터의 aav 전달
|
|
US20180282722A1
(en)
*
|
2016-11-21 |
2018-10-04 |
Massachusetts Institute Of Technology |
Chimeric DNA:RNA Guide for High Accuracy Cas9 Genome Editing
|
|
KR20190082318A
(ko)
*
|
2016-11-22 |
2019-07-09 |
인티그레이티드 디엔에이 테크놀로지스 아이엔씨. |
Crispr/cpf1 시스템 및 방법
|
|
US9816093B1
(en)
*
|
2016-12-06 |
2017-11-14 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
WO2018111947A1
(en)
|
2016-12-12 |
2018-06-21 |
Integrated Dna Technologies, Inc. |
Genome editing enhancement
|
|
EP3555297A1
(en)
|
2016-12-19 |
2019-10-23 |
Editas Medicine, Inc. |
Assessing nuclease cleavage
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
EP3562942A4
(en)
*
|
2016-12-28 |
2020-12-09 |
Ionis Pharmaceuticals, Inc. |
MODIFIED CRISPR-RNA AND ITS USES
|
|
JP7229923B2
(ja)
|
2017-01-06 |
2023-02-28 |
エディタス・メディシン、インコーポレイテッド |
ヌクレアーゼ切断を評価する方法
|
|
CA3052099A1
(en)
*
|
2017-01-30 |
2018-08-02 |
Mathias LABS |
Repair template linkage to endonucleases for genome engineering
|
|
EP3592853A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Suppression of pain by gene editing
|
|
US12390514B2
(en)
|
2017-03-09 |
2025-08-19 |
President And Fellows Of Harvard College |
Cancer vaccine
|
|
US11542496B2
(en)
|
2017-03-10 |
2023-01-03 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
KR20240116572A
(ko)
|
2017-03-23 |
2024-07-29 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제
|
|
US10876101B2
(en)
|
2017-03-28 |
2020-12-29 |
Locanabio, Inc. |
CRISPR-associated (Cas) protein
|
|
US11499151B2
(en)
|
2017-04-28 |
2022-11-15 |
Editas Medicine, Inc. |
Methods and systems for analyzing guide RNA molecules
|
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
|
CN108977442B
(zh)
*
|
2017-06-05 |
2023-01-06 |
广州市锐博生物科技有限公司 |
用于dna编辑的系统及其应用
|
|
CA3102054A1
(en)
|
2017-06-05 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Genomic safe harbors for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies
|
|
WO2018226880A1
(en)
|
2017-06-06 |
2018-12-13 |
Zymergen Inc. |
A htp genomic engineering platform for improving escherichia coli
|
|
WO2018226900A2
(en)
|
2017-06-06 |
2018-12-13 |
Zymergen Inc. |
A htp genomic engineering platform for improving fungal strains
|
|
US20200190508A1
(en)
*
|
2017-06-07 |
2020-06-18 |
Arc Bio, Llc |
Creation and use of guide nucleic acids
|
|
MX2019014640A
(es)
|
2017-06-09 |
2020-10-05 |
Editas Medicine Inc |
Nucleasas de repeticiones palíndromicas agrupadas y regularmente interespaciadas de proteina asociada 9 (cas9) genomanipuladas.
|
|
KR102634727B1
(ko)
|
2017-06-14 |
2024-02-07 |
위스콘신 얼럼나이 리서어치 화운데이션 |
변형된 가이드 rna, crispr-리보뉴클레오프로테인 복합체 및 사용 방법
|
|
US11866726B2
(en)
|
2017-07-14 |
2024-01-09 |
Editas Medicine, Inc. |
Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
|
|
CN112501254B
(zh)
|
2017-07-14 |
2024-07-19 |
上海吐露港生物科技有限公司 |
一种Cas蛋白的用途及靶标核酸分子的检测方法和试剂盒
|
|
US11584955B2
(en)
*
|
2017-07-14 |
2023-02-21 |
Shanghai Tolo Biotechnology Company Limited |
Application of Cas protein, method for detecting target nucleic acid molecule and kit
|
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
|
EP3665279B1
(en)
|
2017-08-09 |
2023-07-19 |
Benson Hill, Inc. |
Compositions and methods for modifying genomes
|
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
WO2019046540A1
(en)
|
2017-08-31 |
2019-03-07 |
New York Genome Center, Inc. |
METHODS AND COMPOSITIONS COMPRISING CRISPR-CPF1 AND APPROVED GUIDING CRISPR RNAES FOR PROGRAMMABLE GENOMIC DELETIONS
|
|
KR20250107288A
(ko)
|
2017-10-16 |
2025-07-11 |
더 브로드 인스티튜트, 인코퍼레이티드 |
아데노신 염기 편집제의 용도
|
|
CN120310773A
(zh)
|
2017-11-16 |
2025-07-15 |
阿斯利康(瑞典)有限公司 |
用于改善基于Cas9的敲入策略的有效性的组合物和方法
|
|
US20210002609A1
(en)
|
2017-12-05 |
2021-01-07 |
Caribou Biosciences, Inc. |
Modified lymphocytes
|
|
EP3724216A1
(en)
|
2017-12-15 |
2020-10-21 |
Dana Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
WO2019147743A1
(en)
*
|
2018-01-26 |
2019-08-01 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide rna and its applications
|
|
WO2019152941A1
(en)
|
2018-02-05 |
2019-08-08 |
Caribou Biosciences, Inc. |
Engineered gut microbes for reduction of reactivation of detoxified drugs
|
|
WO2019165168A1
(en)
|
2018-02-23 |
2019-08-29 |
Pioneer Hi-Bred International, Inc. |
Novel cas9 orthologs
|
|
WO2019173248A1
(en)
|
2018-03-07 |
2019-09-12 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
KR102922694B1
(ko)
|
2018-04-19 |
2026-02-03 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
유전자 편집을 위한 조성물 및 방법
|
|
KR20210045360A
(ko)
|
2018-05-16 |
2021-04-26 |
신테고 코포레이션 |
가이드 rna 설계 및 사용을 위한 방법 및 시스템
|
|
US12157760B2
(en)
|
2018-05-23 |
2024-12-03 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
US10227576B1
(en)
|
2018-06-13 |
2019-03-12 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
CN119490976B
(zh)
*
|
2018-06-13 |
2026-03-31 |
卡里布生物科学公司 |
改造的cascade组分和cascade复合体
|
|
US12227776B2
(en)
|
2018-06-13 |
2025-02-18 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
EP3823633A4
(en)
|
2018-06-29 |
2023-05-03 |
Editas Medicine, Inc. |
SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
|
|
US12522807B2
(en)
|
2018-07-09 |
2026-01-13 |
The Broad Institute, Inc. |
RNA programmable epigenetic RNA modifiers and uses thereof
|
|
CN112654702B
(zh)
|
2018-09-07 |
2025-05-13 |
阿斯利康(瑞典)有限公司 |
改进的核酸酶的组合物和方法
|
|
US12103956B2
(en)
|
2018-10-01 |
2024-10-01 |
Caribou Biosciences, Inc. |
Suicide module compositions and methods
|
|
KR102126573B1
(ko)
|
2018-10-18 |
2020-06-26 |
대한민국 |
CRISPR-Cas9 시스템을 이용한 유색고약버섯의 리그닌 분해효소의 유전자 편집방법 및 이의 용도
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
SG11202104409YA
(en)
*
|
2018-10-31 |
2021-05-28 |
Zymergen Inc |
Multiplexed deterministic assembly of dna libraries
|
|
US11739320B2
(en)
|
2018-11-05 |
2023-08-29 |
Wisconsin Alumni Research Foundation |
Gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases
|
|
WO2020123887A2
(en)
|
2018-12-14 |
2020-06-18 |
Pioneer Hi-Bred International, Inc. |
Novel crispr-cas systems for genome editing
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
CN113874503A
(zh)
*
|
2019-01-25 |
2021-12-31 |
辛瑟高公司 |
用于调节crispr活性的系统和方法
|
|
WO2020176389A1
(en)
|
2019-02-25 |
2020-09-03 |
Caribou Biosciences, Inc. |
Plasmids for gene editing
|
|
US11053515B2
(en)
|
2019-03-08 |
2021-07-06 |
Zymergen Inc. |
Pooled genome editing in microbes
|
|
CN113728106A
(zh)
|
2019-03-08 |
2021-11-30 |
齐默尔根公司 |
微生物中的迭代基因组编辑
|
|
WO2020191233A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
US10982187B2
(en)
|
2019-03-26 |
2021-04-20 |
Genus Plc |
Bos taurus variety ‘HO840003150607238’ and methods of use thereof
|
|
US12473543B2
(en)
|
2019-04-17 |
2025-11-18 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
US10975351B2
(en)
|
2019-06-17 |
2021-04-13 |
Abs Global, Inc. |
Bos taurus variety ‘JE840003146074527’ and methods of use therof
|
|
MX2022002642A
(es)
*
|
2019-09-05 |
2022-06-14 |
Benson Hill Inc |
Composiciones y metodos para modificar genomas.
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
US20230002761A1
(en)
|
2019-11-19 |
2023-01-05 |
Benson Hill, Inc. |
Anti-bacterial crispr compositions and methods
|
|
EP4438729A3
(en)
|
2019-12-09 |
2025-03-26 |
Caribou Biosciences, Inc. |
Crispr abasic restricted nucleotides and crispr accuracy via analogs
|
|
AU2021216418A1
(en)
*
|
2020-02-05 |
2022-09-01 |
Danmarks Tekniske Universitet |
Compositions and methods for targeting, editing or modifying human genes
|
|
WO2021173734A1
(en)
*
|
2020-02-24 |
2021-09-02 |
The Broad Institute, Inc. |
Novel type iv and type i crispr-cas systems and methods of use thereof
|
|
EP4133069A2
(en)
|
2020-04-08 |
2023-02-15 |
Astrazeneca AB |
Compositions and methods for improved site-specific modification
|
|
IL297761A
(en)
|
2020-05-08 |
2022-12-01 |
Broad Inst Inc |
Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence
|
|
CN115956120A
(zh)
*
|
2020-05-12 |
2023-04-11 |
马萨诸塞大学 |
用于crispr基因组编辑的修饰的指导rna
|
|
MX2023004505A
(es)
*
|
2020-10-19 |
2023-05-10 |
Caribou Biosciences Inc |
Polinucleotidos que contienen adn y guias para sistemas crispr de tipo v, y metodos de fabricacion y uso de los mismos.
|
|
CN112301162B
(zh)
*
|
2020-10-22 |
2023-09-22 |
清华-伯克利深圳学院筹备办公室 |
同时检测dna病毒和rna病毒的病毒核酸检测方法
|
|
AU2022227650A1
(en)
*
|
2021-02-25 |
2023-10-12 |
Celyntra Therapeutics Sa |
Compositions and methods for targeting, editing, or modifying genes
|
|
WO2022214522A2
(en)
|
2021-04-07 |
2022-10-13 |
Astrazeneca Ab |
Compositions and methods for site-specific modification
|
|
IL311607A
(en)
*
|
2021-09-22 |
2024-05-01 |
Verve Therapeutics Inc |
PCSK9 or ANGPTL3 gene editing and preparations and methods for using them to treat the disease
|
|
WO2023052508A2
(en)
|
2021-09-30 |
2023-04-06 |
Astrazeneca Ab |
Use of inhibitors to increase efficiency of crispr/cas insertions
|
|
US20250019739A1
(en)
|
2021-10-26 |
2025-01-16 |
Caribou Biosciences, Inc. |
Exonuclease-coupled real-time endonuclease activity assay
|
|
WO2023107899A2
(en)
|
2021-12-07 |
2023-06-15 |
Caribou Biosciences, Inc. |
A method of capturing crispr endonuclease cleavage products
|
|
WO2023185697A2
(en)
*
|
2022-03-29 |
2023-10-05 |
Accuredit Therapeutics (Suzhou) Co., Ltd. |
Compositions and methods for treatment of transthyretin amyloidosis
|
|
EP4508211A2
(en)
*
|
2022-04-13 |
2025-02-19 |
Caribou Biosciences, Inc. |
Therapeutic applications of crispr type v systems
|
|
WO2023224327A1
(ko)
*
|
2022-05-20 |
2023-11-23 |
한국생명공학연구원 |
오토라이신을 활용한 미세조류의 유전자 교정 효율을 증대시키기 위한 시스템 및 방법
|
|
EP4504764A1
(en)
|
2022-05-26 |
2025-02-12 |
Caribou Biosciences, Inc. |
Cytokine-receptor fusions for immune cell stimulation
|
|
IL316804A
(en)
|
2022-06-06 |
2025-01-01 |
Caribou Biosciences Inc |
Treating autoimmune diseases with engineered immune cells
|
|
JP2025511466A
(ja)
|
2022-08-26 |
2025-04-16 |
広州瑞風生物科技有限公司 |
CRISPR-Cas13システム及びその使用
|
|
AU2023353989A1
(en)
|
2022-09-30 |
2025-02-27 |
Caribou Biosciences, Inc. |
Anti-ror1 chimeric antigen receptors (cars), cells expressing the cars and related methods
|
|
EP4584283A1
(en)
|
2022-11-14 |
2025-07-16 |
Caribou Biosciences, Inc. |
Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
|
|
EP4414452A1
(en)
*
|
2023-02-13 |
2024-08-14 |
Universidad de Granada |
Dual-guide rna composition for executing a single-guide rna crispr-associated system
|
|
EP4689155A1
(en)
|
2023-03-29 |
2026-02-11 |
Astrazeneca AB |
Use of inhibitors to increase efficiency of crispr/cas insertions
|
|
EP4704886A1
(en)
|
2023-05-01 |
2026-03-11 |
Caribou Biosciences, Inc. |
Treatment of autoimmune diseases with bcma-targeting engineered immune cells
|
|
AU2024270764A1
(en)
|
2023-05-15 |
2025-12-04 |
Nchroma Bio, Inc. |
Compositions and methods for epigenetic regulation of hbv gene expression
|
|
WO2025006880A1
(en)
|
2023-06-29 |
2025-01-02 |
Caribou Biosciences, Inc. |
Diagnostic and therapeutic methods for use with ror1 antagonists
|
|
WO2025024676A1
(en)
|
2023-07-26 |
2025-01-30 |
Caribou Biosciences, Inc. |
In vitro validation methods for cd19-targeting cell therapies
|
|
WO2025026439A1
(zh)
|
2023-08-02 |
2025-02-06 |
广州瑞风生物科技有限公司 |
基因编辑系统及其应用
|
|
CN119614679A
(zh)
*
|
2023-09-14 |
2025-03-14 |
厦门大学 |
一款通用型核酸检测平台
|
|
WO2025064930A1
(en)
*
|
2023-09-20 |
2025-03-27 |
Emory University |
Nucleic acid hairpin based triggered hydrogels and uses thereof
|
|
WO2025117745A1
(en)
|
2023-12-01 |
2025-06-05 |
Caribou Biosciences, Inc. |
Methods and compositions for improving precision of endonuclease-mediated genome editing
|
|
WO2025193609A1
(en)
|
2024-03-11 |
2025-09-18 |
Caribou Biosciences, Inc. |
Methods and compositions for cost-effective assessment of nucleic acid transcripts and isoforms in cells
|
|
WO2025193386A1
(en)
|
2024-03-13 |
2025-09-18 |
Caribou Biosciences, Inc. |
Treatment regimens for autoimmune disease with cd19-targeting engineered immune cells
|
|
WO2026024468A1
(en)
|
2024-07-26 |
2026-01-29 |
Caribou Biosciences, Inc. |
Modular linked chimeric antigen receptors
|
|
WO2026050087A1
(en)
|
2024-08-27 |
2026-03-05 |
Caribou Biosciences, Inc. |
Real-time crispr endonuclease activity assay
|
|
US20260085302A1
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for controlling plant pests
|
|
US20260085301A1
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for modifying genomes
|
|
WO2026083309A1
(en)
|
2024-10-17 |
2026-04-23 |
Astrazeneca Ab |
Use of inhibitors or modulators of artemis in gene editing
|