|
MX2013010911A
(es)
|
2011-03-23 |
2015-03-03 |
Pioneer Hi Bred Int |
Metodos para producir un locus de rasgo transgenico complejo.
|
|
JP6261500B2
(ja)
|
2011-07-22 |
2018-01-17 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ヌクレアーゼ切断特異性の評価および改善
|
|
US10760064B2
(en)
|
2013-03-15 |
2020-09-01 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
AU2014227653B2
(en)
|
2013-03-15 |
2017-04-20 |
The General Hospital Corporation |
Using RNA-guided foki nucleases (RFNs) to increase specificity for RNA-guided genome editing
|
|
SI2986729T1
(sl)
|
2013-04-16 |
2019-02-28 |
Regeneron Pharmaceuticals, Inc. |
Ciljana sprememba genoma podgane
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
CA3109801C
(en)
|
2013-08-22 |
2024-01-09 |
Andrew Cigan |
Plant genome modification using guide rna/cas endonuclease systems and methods of use
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
US9388430B2
(en)
|
2013-09-06 |
2016-07-12 |
President And Fellows Of Harvard College |
Cas9-recombinase fusion proteins and uses thereof
|
|
US9340799B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
MRNA-sensing switchable gRNAs
|
|
US9546384B2
(en)
|
2013-12-11 |
2017-01-17 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a mouse genome
|
|
US20150165054A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting caspase-9 point mutations
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
CN108064129A
(zh)
|
2014-09-12 |
2018-05-22 |
纳幕尔杜邦公司 |
玉米和大豆中复合性状基因座的位点特异性整合位点的产生和使用方法
|
|
EP3204496A1
(en)
|
2014-10-10 |
2017-08-16 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
|
GB201418965D0
(https=)
|
2014-10-24 |
2014-12-10 |
Ospedale San Raffaele And Fond Telethon |
|
|
CA2963820A1
(en)
|
2014-11-07 |
2016-05-12 |
Editas Medicine, Inc. |
Methods for improving crispr/cas-mediated genome-editing
|
|
EP3250691B9
(en)
|
2015-01-28 |
2023-08-02 |
Caribou Biosciences, Inc. |
Crispr hybrid dna/rna polynucleotides and methods of use
|
|
BR112017017260A2
(pt)
|
2015-03-27 |
2018-04-17 |
Du Pont |
construções de dna, vetor, célula, plantas, semente, método de expressão de rna e método de modificação de local alvo
|
|
GB201506509D0
(en)
|
2015-04-16 |
2015-06-03 |
Univ Wageningen |
Nuclease-mediated genome editing
|
|
AU2016261358B2
(en)
|
2015-05-11 |
2021-09-16 |
Editas Medicine, Inc. |
Optimized CRISPR/Cas9 systems and methods for gene editing in stem cells
|
|
EP3307887A1
(en)
|
2015-06-09 |
2018-04-18 |
Editas Medicine, Inc. |
Crispr/cas-related methods and compositions for improving transplantation
|
|
US20160362667A1
(en)
*
|
2015-06-10 |
2016-12-15 |
Caribou Biosciences, Inc. |
CRISPR-Cas Compositions and Methods
|
|
US9790490B2
(en)
*
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
US10648020B2
(en)
|
2015-06-18 |
2020-05-12 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
|
EP4545544A3
(en)
|
2015-06-29 |
2025-10-08 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and modified single crispr rna and uses thereof
|
|
US11279928B2
(en)
|
2015-06-29 |
2022-03-22 |
Massachusetts Institute Of Technology |
Compositions comprising nucleic acids and methods of using the same
|
|
US9926546B2
(en)
|
2015-08-28 |
2018-03-27 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
US9512446B1
(en)
|
2015-08-28 |
2016-12-06 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
AU2016326711B2
(en)
|
2015-09-24 |
2022-11-03 |
Editas Medicine, Inc. |
Use of exonucleases to improve CRISPR/Cas-mediated genome editing
|
|
JP7109784B2
(ja)
|
2015-10-23 |
2022-08-01 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
遺伝子編集のための進化したＣａｓ９蛋白質
|
|
DK3350327T3
(en)
|
2015-10-23 |
2019-01-21 |
Caribou Biosciences Inc |
CONSTRUCTED CRISPR CLASS-2-NUCLEIC ACID TARGETING-NUCLEIC ACID
|
|
AU2016363024B2
(en)
*
|
2015-12-04 |
2020-01-30 |
Caribou Biosciences, Inc. |
Engineered nucleic-acid targeting nucleic acids
|
|
CN109310784B
(zh)
|
2015-12-07 |
2022-08-19 |
阿克生物公司 |
用于制备和使用指导核酸的方法和组合物
|
|
US11208649B2
(en)
|
2015-12-07 |
2021-12-28 |
Zymergen Inc. |
HTP genomic engineering platform
|
|
JP6821598B2
(ja)
|
2015-12-07 |
2021-01-27 |
ザイマージェン インコーポレイテッド |
Ｃｏｒｙｎｅｂａｃｔｅｒｉｕｍ ｇｌｕｔａｍｉｃｕｍ由来のプロモーター
|
|
US9988624B2
(en)
|
2015-12-07 |
2018-06-05 |
Zymergen Inc. |
Microbial strain improvement by a HTP genomic engineering platform
|
|
US11845933B2
(en)
|
2016-02-03 |
2023-12-19 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide RNA and its applications
|
|
US9896696B2
(en)
*
|
2016-02-15 |
2018-02-20 |
Benson Hill Biosystems, Inc. |
Compositions and methods for modifying genomes
|
|
EP3433363A1
(en)
|
2016-03-25 |
2019-01-30 |
Editas Medicine, Inc. |
Genome editing systems comprising repair-modulating enzyme molecules and methods of their use
|
|
WO2017180694A1
(en)
|
2016-04-13 |
2017-10-19 |
Editas Medicine, Inc. |
Cas9 fusion molecules gene editing systems, and methods of use thereof
|
|
CN110382692A
(zh)
|
2016-04-19 |
2019-10-25 |
博德研究所 |
新型crispr酶以及系统
|
|
CN106244591A
(zh)
*
|
2016-08-23 |
2016-12-21 |
苏州吉玛基因股份有限公司 |
修饰crRNA在CRISPR/Cpf1基因编辑系统中的应用
|
|
JP2019517261A
(ja)
|
2016-06-01 |
2019-06-24 |
カーヴェーエス ザート ソシエタス・ヨーロピアＫｗｓ Ｓａａｔ Ｓｅ |
ゲノム操作のためのハイブリッド核酸配列
|
|
US10767175B2
(en)
|
2016-06-08 |
2020-09-08 |
Agilent Technologies, Inc. |
High specificity genome editing using chemically modified guide RNAs
|
|
EP3478833A4
(en)
|
2016-06-30 |
2019-10-02 |
Zymergen, Inc. |
METHOD FOR PRODUCING A BACTERIAL HEMOGLOBIN LIBRARY AND ITS USE
|
|
JP2019519241A
(ja)
|
2016-06-30 |
2019-07-11 |
ザイマージェン インコーポレイテッド |
グルコース透過酵素ライブラリーを生成するための方法およびその使用
|
|
WO2018009822A1
(en)
*
|
2016-07-08 |
2018-01-11 |
Ohio State Innovation Foundation |
Modified nucleic acids, hybrid guide rnas, and uses thereof
|
|
KR102547316B1
(ko)
|
2016-08-03 |
2023-06-23 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
|
WO2018031950A1
(en)
|
2016-08-12 |
2018-02-15 |
Caribou Biosciences, Inc. |
Protein engineering methods
|
|
CN109844123A
(zh)
*
|
2016-08-19 |
2019-06-04 |
株式会社图尔金 |
经人工操纵的血管生成调控系统
|
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
CA3034931A1
(en)
|
2016-09-23 |
2018-03-29 |
Board Of Trustees Of Southern Illinois University |
Tuning crispr/cas9 activity with chemically modified nucleotide substitutions
|
|
US11242542B2
(en)
|
2016-10-07 |
2022-02-08 |
Integrated Dna Technologies, Inc. |
S. pyogenes Cas9 mutant genes and polypeptides encoded by same
|
|
CN118726313A
(zh)
|
2016-10-07 |
2024-10-01 |
综合Dna技术公司 |
化脓链球菌cas9突变基因和由其编码的多肽
|
|
EP3526320A1
(en)
|
2016-10-14 |
2019-08-21 |
President and Fellows of Harvard College |
Aav delivery of nucleobase editors
|
|
US20180282722A1
(en)
*
|
2016-11-21 |
2018-10-04 |
Massachusetts Institute Of Technology |
Chimeric DNA:RNA Guide for High Accuracy Cas9 Genome Editing
|
|
WO2018098383A1
(en)
*
|
2016-11-22 |
2018-05-31 |
Integrated Dna Technologies, Inc. |
Crispr/cpf1 systems and methods
|
|
US9816093B1
(en)
|
2016-12-06 |
2017-11-14 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
WO2018111947A1
(en)
|
2016-12-12 |
2018-06-21 |
Integrated Dna Technologies, Inc. |
Genome editing enhancement
|
|
WO2018119010A1
(en)
|
2016-12-19 |
2018-06-28 |
Editas Medicine, Inc. |
Assessing nuclease cleavage
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
WO2018125964A1
(en)
*
|
2016-12-28 |
2018-07-05 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and uses thereof
|
|
EP3565907B1
(en)
|
2017-01-06 |
2022-05-04 |
Editas Medicine, Inc. |
Methods of assessing nuclease cleavage
|
|
ES2950676T3
(es)
*
|
2017-01-30 |
2023-10-11 |
Kws Saat Se & Co Kgaa |
Reparación de enlace de plantillas a endonucleasas para modificación de genes
|
|
EP3592853A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Suppression of pain by gene editing
|
|
JP2020510038A
(ja)
|
2017-03-09 |
2020-04-02 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
がんワクチン
|
|
JP2020510439A
(ja)
|
2017-03-10 |
2020-04-09 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
シトシンからグアニンへの塩基編集因子
|
|
CA3057192A1
(en)
|
2017-03-23 |
2018-09-27 |
President And Fellows Of Harvard College |
Nucleobase editors comprising nucleic acid programmable dna binding proteins
|
|
US10876101B2
(en)
|
2017-03-28 |
2020-12-29 |
Locanabio, Inc. |
CRISPR-associated (Cas) protein
|
|
US11499151B2
(en)
|
2017-04-28 |
2022-11-15 |
Editas Medicine, Inc. |
Methods and systems for analyzing guide RNA molecules
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
CN108977442B
(zh)
*
|
2017-06-05 |
2023-01-06 |
广州市锐博生物科技有限公司 |
用于dna编辑的系统及其应用
|
|
CA3102054A1
(en)
|
2017-06-05 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Genomic safe harbors for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies
|
|
KR20200026878A
(ko)
|
2017-06-06 |
2020-03-11 |
지머젠 인코포레이티드 |
균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
|
|
KR20200026874A
(ko)
|
2017-06-06 |
2020-03-11 |
지머젠 인코포레이티드 |
대장균 개량을 위한 htp 게놈 공학 플랫폼
|
|
AU2018279112B2
(en)
*
|
2017-06-07 |
2024-11-07 |
Arc Bio, Llc |
Creation and use of guide nucleic acids
|
|
WO2018227114A1
(en)
|
2017-06-09 |
2018-12-13 |
Editas Medicine, Inc. |
Engineered cas9 nucleases
|
|
WO2018232114A1
(en)
|
2017-06-14 |
2018-12-20 |
Wisconsin Alumni Research Foundation |
Modified guide rnas, crispr-ribonucleotprotein complexes and methods of use
|
|
CN107488710B
(zh)
|
2017-07-14 |
2020-09-22 |
上海吐露港生物科技有限公司 |
一种Cas蛋白的用途及靶标核酸分子的检测方法和试剂盒
|
|
US11866726B2
(en)
|
2017-07-14 |
2024-01-09 |
Editas Medicine, Inc. |
Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
|
|
US11584955B2
(en)
*
|
2017-07-14 |
2023-02-21 |
Shanghai Tolo Biotechnology Company Limited |
Application of Cas protein, method for detecting target nucleic acid molecule and kit
|
|
WO2019023680A1
(en)
|
2017-07-28 |
2019-01-31 |
President And Fellows Of Harvard College |
METHODS AND COMPOSITIONS FOR EVOLUTION OF BASIC EDITORS USING PHAGE-ASSISTED CONTINUOUS EVOLUTION (PACE)
|
|
JP7355730B2
(ja)
|
2017-08-09 |
2023-10-03 |
ベンソン ヒル，インコーポレイティド |
ゲノムを修飾するための組成物及び方法
|
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
WO2019046540A1
(en)
|
2017-08-31 |
2019-03-07 |
New York Genome Center, Inc. |
METHODS AND COMPOSITIONS COMPRISING CRISPR-CPF1 AND APPROVED GUIDING CRISPR RNAES FOR PROGRAMMABLE GENOMIC DELETIONS
|
|
KR20250107288A
(ko)
|
2017-10-16 |
2025-07-11 |
더 브로드 인스티튜트, 인코퍼레이티드 |
아데노신 염기 편집제의 용도
|
|
CN111448313A
(zh)
|
2017-11-16 |
2020-07-24 |
阿斯利康(瑞典)有限公司 |
用于改善基于Cas9的敲入策略的有效性的组合物和方法
|
|
WO2019113132A1
(en)
|
2017-12-05 |
2019-06-13 |
Caribou Biosciences, Inc. |
Modified lymphocytes
|
|
WO2019118949A1
(en)
|
2017-12-15 |
2019-06-20 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
US20200354413A1
(en)
|
2017-12-15 |
2020-11-12 |
Dana-Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
|
WO2019147743A1
(en)
*
|
2018-01-26 |
2019-08-01 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide rna and its applications
|
|
US20210093679A1
(en)
|
2018-02-05 |
2021-04-01 |
Novome Biotechnologies, Inc. |
Engineered gut microbes and uses thereof
|
|
KR20200124702A
(ko)
|
2018-02-23 |
2020-11-03 |
파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 |
신규한 cas9 오르소로그
|
|
WO2019173248A1
(en)
|
2018-03-07 |
2019-09-12 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
JP7555822B2
(ja)
|
2018-04-19 |
2024-09-25 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア |
ゲノム編集のための組成物および方法
|
|
KR20210045360A
(ko)
|
2018-05-16 |
2021-04-26 |
신테고 코포레이션 |
가이드 rna 설계 및 사용을 위한 방법 및 시스템
|
|
EP3797160A1
(en)
|
2018-05-23 |
2021-03-31 |
The Broad Institute Inc. |
Base editors and uses thereof
|
|
US10227576B1
(en)
|
2018-06-13 |
2019-03-12 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
JP6965466B2
(ja)
*
|
2018-06-13 |
2021-11-10 |
カリブー・バイオサイエンシーズ・インコーポレイテッド |
操作されたカスケード構成要素およびカスケード複合体
|
|
US12227776B2
(en)
|
2018-06-13 |
2025-02-18 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
EP3823633A4
(en)
|
2018-06-29 |
2023-05-03 |
Editas Medicine, Inc. |
SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
|
|
US12522807B2
(en)
|
2018-07-09 |
2026-01-13 |
The Broad Institute, Inc. |
RNA programmable epigenetic RNA modifiers and uses thereof
|
|
EP3847251A1
(en)
|
2018-09-07 |
2021-07-14 |
Astrazeneca AB |
Compositions and methods for improved nucleases
|
|
EP3833682B1
(en)
|
2018-10-01 |
2022-08-17 |
Caribou Biosciences, Inc. |
Suicide module compositions and methods
|
|
KR102126573B1
(ko)
|
2018-10-18 |
2020-06-26 |
대한민국 |
CRISPR-Cas9 시스템을 이용한 유색고약버섯의 리그닌 분해효소의 유전자 편집방법 및 이의 용도
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
EP3874037A4
(en)
*
|
2018-10-31 |
2021-12-15 |
Zymergen, Inc. |
DETERMINIST MULTIPLEXED SET OF DNA LIBRARIES
|
|
US11739320B2
(en)
|
2018-11-05 |
2023-08-29 |
Wisconsin Alumni Research Foundation |
Gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases
|
|
US12365888B2
(en)
|
2018-12-14 |
2025-07-22 |
Pioneer Hi-Bred International, Inc. |
CRISPR-Cas systems for genome editing
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
AU2020210884A1
(en)
|
2019-01-25 |
2021-08-12 |
Synthego Corporation |
Systems and methods for modulating CRISPR activity
|
|
US20220290120A1
(en)
|
2019-02-25 |
2022-09-15 |
Novome Biotechnologies, Inc. |
Plasmids for gene editing
|
|
US11053515B2
(en)
|
2019-03-08 |
2021-07-06 |
Zymergen Inc. |
Pooled genome editing in microbes
|
|
CN113728106A
(zh)
|
2019-03-08 |
2021-11-30 |
齐默尔根公司 |
微生物中的迭代基因组编辑
|
|
JP7657726B2
(ja)
|
2019-03-19 |
2025-04-07 |
ザ ブロード インスティテュート，インコーポレーテッド |
編集ヌクレオチド配列を編集するための方法および組成物
|
|
US10982187B2
(en)
|
2019-03-26 |
2021-04-20 |
Genus Plc |
Bos taurus variety ‘HO840003150607238’ and methods of use thereof
|
|
US12473543B2
(en)
|
2019-04-17 |
2025-11-18 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
US10975351B2
(en)
|
2019-06-17 |
2021-04-13 |
Abs Global, Inc. |
Bos taurus variety ‘JE840003146074527’ and methods of use therof
|
|
CA3153301A1
(en)
*
|
2019-09-05 |
2021-03-11 |
Benson Hill, Inc. |
Compositions and methods for modifying genomes
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
US20230002761A1
(en)
|
2019-11-19 |
2023-01-05 |
Benson Hill, Inc. |
Anti-bacterial crispr compositions and methods
|
|
EP4438729A3
(en)
|
2019-12-09 |
2025-03-26 |
Caribou Biosciences, Inc. |
Crispr abasic restricted nucleotides and crispr accuracy via analogs
|
|
CA3166430A1
(en)
*
|
2020-02-05 |
2021-08-12 |
Ryan T. Gill |
Compositions and methods for targeting, editing or modifying human genes
|
|
WO2021173734A1
(en)
*
|
2020-02-24 |
2021-09-02 |
The Broad Institute, Inc. |
Novel type iv and type i crispr-cas systems and methods of use thereof
|
|
CN115427566A
(zh)
|
2020-04-08 |
2022-12-02 |
阿斯利康(瑞典)有限公司 |
用于改善的位点特异性修饰的组合物和方法
|
|
DE112021002672T5
(de)
|
2020-05-08 |
2023-04-13 |
President And Fellows Of Harvard College |
Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz
|
|
WO2021231606A2
(en)
*
|
2020-05-12 |
2021-11-18 |
University Of Massachusetts |
Modified guide rnas for crispr genome editing
|
|
JP7698715B2
(ja)
*
|
2020-10-19 |
2025-06-25 |
カリブー・バイオサイエンシーズ・インコーポレイテッド |
Ｃｒｉｓｐｒ ｖ型系のためのｄｎａ含有ポリヌクレオチドおよびガイド、ならびにこれらを製造する方法および使用する方法
|
|
CN112301162B
(zh)
*
|
2020-10-22 |
2023-09-22 |
清华-伯克利深圳学院筹备办公室 |
同时检测dna病毒和rna病毒的病毒核酸检测方法
|
|
EP4298212A4
(en)
*
|
2021-02-25 |
2026-04-15 |
Celyntra Therapeutics Sa |
Compositions and methods for targeting, editing, or modifying genes
|
|
JP2024513087A
(ja)
|
2021-04-07 |
2024-03-21 |
アストラゼネカ・アクチエボラーグ |
部位特異的改変のための組成物及び方法
|
|
AU2022349449A1
(en)
*
|
2021-09-22 |
2024-04-18 |
Verve Therapeutics, Inc. |
Gene editing of pcsk9 or angptl3 and compositions and methods of using same for treatment of disease
|
|
WO2023052508A2
(en)
|
2021-09-30 |
2023-04-06 |
Astrazeneca Ab |
Use of inhibitors to increase efficiency of crispr/cas insertions
|
|
JP7765627B2
(ja)
|
2021-10-26 |
2025-11-06 |
カリブー・バイオサイエンシーズ・インコーポレイテッド |
エキソヌクレアーゼ連動式リアルタイムエンドヌクレアーゼ活性アッセイ
|
|
CA3242053A1
(en)
*
|
2021-12-07 |
2023-06-15 |
Caribou Biosciences, Inc. |
A method of capturing crispr endonuclease cleavage products
|
|
WO2023185697A2
(en)
*
|
2022-03-29 |
2023-10-05 |
Accuredit Therapeutics (Suzhou) Co., Ltd. |
Compositions and methods for treatment of transthyretin amyloidosis
|
|
IL316048A
(en)
*
|
2022-04-13 |
2024-11-01 |
Caribou Biosciences Inc |
Therapeutic applications of V-type CRISPR systems
|
|
WO2023224327A1
(ko)
*
|
2022-05-20 |
2023-11-23 |
한국생명공학연구원 |
오토라이신을 활용한 미세조류의 유전자 교정 효율을 증대시키기 위한 시스템 및 방법
|
|
US20260035424A1
(en)
|
2022-05-26 |
2026-02-05 |
Caribou Biosciences, Inc. |
Cytokine-receptor fusions for immune cell stimulation
|
|
AU2023285071B2
(en)
|
2022-06-06 |
2025-02-20 |
Caribou Biosciences, Inc. |
Treatment of autoimmune diseases with engineered immune cells
|
|
WO2024041653A1
(zh)
|
2022-08-26 |
2024-02-29 |
广州瑞风生物科技有限公司 |
一种CRISPR-Cas13系统及其应用
|
|
EP4593871A1
(en)
|
2022-09-30 |
2025-08-06 |
Caribou Biosciences, Inc. |
Anti-ror1 chimeric antigen receptors (cars), car-nk cells and related methods
|
|
EP4584283A1
(en)
|
2022-11-14 |
2025-07-16 |
Caribou Biosciences, Inc. |
Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
|
|
EP4414452A1
(en)
*
|
2023-02-13 |
2024-08-14 |
Universidad de Granada |
Dual-guide rna composition for executing a single-guide rna crispr-associated system
|
|
CN121127605A
(zh)
|
2023-03-29 |
2025-12-12 |
阿斯利康(瑞典)有限公司 |
使用抑制剂来提高CRISPR/Cas插入的效率
|
|
AU2024265453A1
(en)
|
2023-05-01 |
2025-09-25 |
Caribou Biosciences, Inc. |
Treatment of autoimmune diseases with bcma-targeting engineered immune cells
|
|
IL324634A
(en)
|
2023-05-15 |
2026-01-01 |
Nchroma Bio Inc |
Compositions and methods for epigenetic regulation of hbv gene expression
|
|
WO2025006880A1
(en)
|
2023-06-29 |
2025-01-02 |
Caribou Biosciences, Inc. |
Diagnostic and therapeutic methods for use with ror1 antagonists
|
|
WO2025024676A1
(en)
|
2023-07-26 |
2025-01-30 |
Caribou Biosciences, Inc. |
In vitro validation methods for cd19-targeting cell therapies
|
|
CN121816418A
(zh)
|
2023-08-02 |
2026-04-07 |
广州瑞风生物科技股份有限公司 |
基因编辑系统及其应用
|
|
CN119614679A
(zh)
*
|
2023-09-14 |
2025-03-14 |
厦门大学 |
一款通用型核酸检测平台
|
|
WO2025064930A1
(en)
*
|
2023-09-20 |
2025-03-27 |
Emory University |
Nucleic acid hairpin based triggered hydrogels and uses thereof
|
|
WO2025117745A1
(en)
|
2023-12-01 |
2025-06-05 |
Caribou Biosciences, Inc. |
Methods and compositions for improving precision of endonuclease-mediated genome editing
|
|
WO2025193609A1
(en)
|
2024-03-11 |
2025-09-18 |
Caribou Biosciences, Inc. |
Methods and compositions for cost-effective assessment of nucleic acid transcripts and isoforms in cells
|
|
WO2025193386A1
(en)
|
2024-03-13 |
2025-09-18 |
Caribou Biosciences, Inc. |
Treatment regimens for autoimmune disease with cd19-targeting engineered immune cells
|
|
WO2026024468A1
(en)
|
2024-07-26 |
2026-01-29 |
Caribou Biosciences, Inc. |
Modular linked chimeric antigen receptors
|
|
WO2026050087A1
(en)
|
2024-08-27 |
2026-03-05 |
Caribou Biosciences, Inc. |
Real-time crispr endonuclease activity assay
|
|
US20260085302A1
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for controlling plant pests
|
|
US20260085301A1
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for modifying genomes
|