JP2018503373A - がんの予後診断及び治療のための方法及び組成物 - Google Patents
がんの予後診断及び治療のための方法及び組成物 Download PDFInfo
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- JP2018503373A JP2018503373A JP2017534648A JP2017534648A JP2018503373A JP 2018503373 A JP2018503373 A JP 2018503373A JP 2017534648 A JP2017534648 A JP 2017534648A JP 2017534648 A JP2017534648 A JP 2017534648A JP 2018503373 A JP2018503373 A JP 2018503373A
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021031306A JP7325463B2 (ja) | 2014-12-30 | 2021-03-01 | がんの予後診断及び治療のための方法及び組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462098055P | 2014-12-30 | 2014-12-30 | |
| US62/098,055 | 2014-12-30 | ||
| PCT/US2015/067878 WO2016109546A2 (en) | 2014-12-30 | 2015-12-29 | Methods and compositions for prognosis and treatment of cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2021031306A Division JP7325463B2 (ja) | 2014-12-30 | 2021-03-01 | がんの予後診断及び治療のための方法及び組成物 |
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| Publication Number | Publication Date |
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| JP2018503373A true JP2018503373A (ja) | 2018-02-08 |
| JP2018503373A5 JP2018503373A5 (enExample) | 2019-01-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2017534648A Pending JP2018503373A (ja) | 2014-12-30 | 2015-12-29 | がんの予後診断及び治療のための方法及び組成物 |
| JP2021031306A Active JP7325463B2 (ja) | 2014-12-30 | 2021-03-01 | がんの予後診断及び治療のための方法及び組成物 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2021031306A Active JP7325463B2 (ja) | 2014-12-30 | 2021-03-01 | がんの予後診断及び治療のための方法及び組成物 |
Country Status (5)
| Country | Link |
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| US (2) | US11236394B2 (enExample) |
| EP (1) | EP3240908A2 (enExample) |
| JP (2) | JP2018503373A (enExample) |
| CN (1) | CN107208138A (enExample) |
| WO (1) | WO2016109546A2 (enExample) |
Cited By (7)
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| KR102084196B1 (ko) * | 2018-08-29 | 2020-03-03 | 연세대학교 산학협력단 | 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트 |
| WO2021107452A1 (ko) * | 2019-11-29 | 2021-06-03 | 의료법인 성광의료재단 | 면역 세포 치료제에 대한 치료 반응성 예측용 바이오마커 |
| JP2021524744A (ja) * | 2018-05-21 | 2021-09-16 | ナノストリング テクノロジーズ,インコーポレイティド | 分子遺伝子シグネチャーとその使用方法 |
| JP2022511502A (ja) * | 2018-12-05 | 2022-01-31 | ジェネンテック, インコーポレイテッド | がんの免疫療法のための診断方法及び診断用組成物 |
| JP2022527972A (ja) * | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
| JP2024502489A (ja) * | 2021-01-12 | 2024-01-19 | コーニンクレッカ フィリップス エヌ ヴェ | 結腸直腸がん対象者の転帰の予測 |
| WO2024225488A1 (ja) * | 2023-04-27 | 2024-10-31 | 株式会社リプロセル | 抗pd-1抗体療法に応答性である候補がん患者を同定する方法 |
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| TWI715587B (zh) | 2015-05-28 | 2021-01-11 | 美商安可美德藥物股份有限公司 | Tigit結合劑和彼之用途 |
| US12241053B2 (en) | 2015-10-09 | 2025-03-04 | The Brigham And Women's Hospital, Inc. | Modulation of novel immune checkpoint targets |
| EP3400246B1 (en) | 2016-01-08 | 2020-10-21 | H. Hoffnabb-La Roche Ag | Methods of treating cea-positive cancers using pd-1 axis binding antagonists and anti-cea/anti-cd3 bispecific antibodies |
| WO2018029124A1 (en) * | 2016-08-08 | 2018-02-15 | F. Hoffmann-La Roche Ag | Therapeutic and diagnostic methods for cancer |
| JP7235508B2 (ja) * | 2016-11-24 | 2023-03-08 | 第一三共株式会社 | Pd-1免疫チェックポイント阻害剤による治療に対するがんの感受性を予測する方法 |
| CN110662552A (zh) | 2016-11-30 | 2020-01-07 | 昂科梅德制药有限公司 | 包含tigit结合剂的癌症治疗方法 |
| EP3333268A1 (en) * | 2016-12-09 | 2018-06-13 | Institut Paoli Calmettes | Biomarker panel for prognosis of bladder cancer |
| WO2018122249A1 (en) * | 2016-12-28 | 2018-07-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer |
| EP3580349A1 (en) * | 2017-02-07 | 2019-12-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Tim-3 for assessing the severity of cancer |
| CN106950371B (zh) * | 2017-02-17 | 2019-03-08 | 张灏 | Pd-l1、cdk5和ctla4中的至少一种在制备肿瘤诊断试剂盒中的用途 |
| EP3589754B1 (en) | 2017-03-01 | 2023-06-28 | F. Hoffmann-La Roche AG | Diagnostic and therapeutic methods for cancer |
| US10340030B2 (en) | 2017-06-13 | 2019-07-02 | Bostongene Corporation | Systems and methods for identifying cancer treatments from normalized biomarker scores |
| KR102348291B1 (ko) * | 2017-06-14 | 2022-01-07 | 연세대학교 산학협력단 | 암 환자의 치료 반응성을 예측하는 방법 |
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| JP7304558B2 (ja) * | 2017-12-12 | 2023-07-07 | 地方独立行政法人神奈川県立病院機構 | がん免疫療法の予後予測のためのバイオマーカー |
| CN108823309B (zh) * | 2018-06-11 | 2021-11-30 | 北京大学人民医院 | 检测kiaa0125基因表达水平的物质在辅助鉴定急性淋巴细胞白血病中的应用 |
| GB201810190D0 (en) * | 2018-06-21 | 2018-08-08 | Cancer Research Tech Ltd | Prognostic and treatment response predictive method |
| EP3833323A4 (en) * | 2018-08-08 | 2022-08-10 | Cedars-Sinai Medical Center | Compositions and methods for treating cancer and autoimmune diseases |
| US20210338727A1 (en) * | 2018-09-13 | 2021-11-04 | Nkarta, Inc. | Natural killer cell compositions and immunotherapy methods for treating tumors |
| CA3131533A1 (en) | 2019-03-05 | 2020-09-10 | Nkarta, Inc. | Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| CN109880894A (zh) * | 2019-03-05 | 2019-06-14 | 杭州西合森医学检验实验室有限公司 | 基于RNAseq的肿瘤免疫微环境预测模型的构建方法 |
| EP3953712A1 (en) * | 2019-04-10 | 2022-02-16 | Universität Zürich | A method for determining the likelihood of a patient being responsive to cancer immunotherapy |
| JP2022534967A (ja) * | 2019-05-30 | 2022-08-04 | ブリストル-マイヤーズ スクイブ カンパニー | 多腫瘍遺伝子シグネチャーおよびその使用 |
| EP3976040A1 (en) * | 2019-06-01 | 2022-04-06 | Ares Trading S.A. | Pd-1 axis binding antagonist to treat cancer with genetic mutations in specific genes |
| KR102042710B1 (ko) * | 2019-07-02 | 2019-11-08 | 의료법인 성광의료재단 | 면역체크 포인트와 관련된, 난소암 진단용 바이오마커 |
| CN110804642B (zh) * | 2019-09-10 | 2022-06-21 | 清华大学 | Gpr174免疫学功能及其用途 |
| US20210181200A1 (en) * | 2019-12-17 | 2021-06-17 | Women's College Hospital | Ovarian cancer biomarker and methods of using same |
| GB202007099D0 (en) | 2020-05-14 | 2020-07-01 | Kymab Ltd | Tumour biomarkers for immunotherapy |
| KR20230012559A (ko) | 2020-05-19 | 2023-01-26 | 베링거 인겔하임 인터내셔날 게엠베하 | 암 치료를 위한 결합 분자 |
| CN111500733B (zh) * | 2020-05-27 | 2022-03-08 | 中国人民解放军军事科学院军事医学研究院 | 外周血单核细胞中用于非小细胞肺癌早期诊断的分子标记物 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013505008A (ja) * | 2009-09-18 | 2013-02-14 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法 |
| WO2014023706A1 (en) * | 2012-08-06 | 2014-02-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for screening patients with a cancer |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU22545A1 (es) | 1994-11-18 | 1999-03-31 | Centro Inmunologia Molecular | Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico |
| US4943533A (en) | 1984-03-01 | 1990-07-24 | The Regents Of The University Of California | Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor |
| US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| WO1991003489A1 (en) | 1989-09-08 | 1991-03-21 | The Johns Hopkins University | Structural alterations of the egf receptor gene in human gliomas |
| AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| WO1993025673A1 (en) | 1992-06-04 | 1993-12-23 | The Regents Of The University Of California | In vivo gene therapy with intron-free sequence of interest |
| GB9314893D0 (en) | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| PT659439E (pt) | 1993-12-24 | 2002-04-29 | Merck Patent Gmbh | Imunoconjugados |
| IL112248A0 (en) | 1994-01-25 | 1995-03-30 | Warner Lambert Co | Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them |
| IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| US5654307A (en) | 1994-01-25 | 1997-08-05 | Warner-Lambert Company | Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
| EP0772609B1 (en) | 1994-07-21 | 1999-02-24 | Akzo Nobel N.V. | Cyclic ketone peroxide formulations |
| US5910486A (en) | 1994-09-06 | 1999-06-08 | Uab Research Foundation | Methods for modulating protein function in cells using, intracellular antibody homologues |
| US5804396A (en) | 1994-10-12 | 1998-09-08 | Sugen, Inc. | Assay for agents active in proliferative disorders |
| EP2163546B1 (en) | 1995-03-30 | 2016-06-01 | Pfizer Products Inc. | Quinazoline derivatives |
| GB9508565D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quiazoline derivative |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| JPH11507535A (ja) | 1995-06-07 | 1999-07-06 | イムクローン システムズ インコーポレイテッド | 腫瘍の成長を抑制する抗体および抗体フラグメント類 |
| TR199800012T1 (xx) | 1995-07-06 | 1998-04-21 | Novartis Ag | Piroloprimidinler ve preparasyon i�in tatbikler. |
| US5760041A (en) | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
| GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| DE69710712T3 (de) | 1996-04-12 | 2010-12-23 | Warner-Lambert Co. Llc | Umkehrbare inhibitoren von tyrosin kinasen |
| EP0912559B1 (en) | 1996-07-13 | 2002-11-06 | Glaxo Group Limited | Fused heterocyclic compounds as protein tyrosine kinase inhibitors |
| ID18494A (id) | 1996-10-02 | 1998-04-16 | Novartis Ag | Turunan pirazola leburan dan proses pembuatannya |
| UA73073C2 (uk) | 1997-04-03 | 2005-06-15 | Уайт Холдінгз Корпорейшн | Заміщені 3-ціанохіноліни, спосіб їх одержання та фармацевтична композиція |
| US6002008A (en) | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| AU7165698A (en) | 1997-05-06 | 1998-11-27 | American Cyanamid Company | Use of quinazoline compounds for the treatment of polycystic kidney disease |
| ZA986732B (en) | 1997-07-29 | 1999-02-02 | Warner Lambert Co | Irreversible inhibitiors of tyrosine kinases |
| ZA986729B (en) | 1997-07-29 | 1999-02-02 | Warner Lambert Co | Irreversible inhibitors of tyrosine kinases |
| TW436485B (en) | 1997-08-01 | 2001-05-28 | American Cyanamid Co | Substituted quinazoline derivatives |
| HUP0004286A3 (en) | 1997-11-06 | 2002-01-28 | American Cyanamid Co Madison | Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps |
| JP3687900B2 (ja) | 1998-11-19 | 2005-08-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | チロシンキナーゼの不可逆的阻害剤であるn−[4−(3−クロロ−4−フルオロフェニルアミノ)−7−(3−モルホリン−4−イルプロポキシ)キナゾリン−6−イル]アクリルアミド |
| JP5883384B2 (ja) * | 2009-08-13 | 2016-03-15 | ザ ジョンズ ホプキンス ユニバーシティー | 免疫機能を調節する方法 |
| WO2011040532A1 (ja) * | 2009-10-02 | 2011-04-07 | 学校法人 久留米大学 | 癌患者に対する免疫療法の治療効果および/または免疫療法後の予後の予測方法、ならびに該方法に用いる遺伝子セットおよびキット |
| US9404926B2 (en) * | 2010-01-29 | 2016-08-02 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Immune gene signatures in cancer |
| WO2011130624A2 (en) | 2010-04-16 | 2011-10-20 | Immune Disease Institute, Inc. | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| WO2012016332A1 (en) * | 2010-08-04 | 2012-02-09 | Med Biogene Inc. | Prognostic gene signatures for non-small cell lung cancer |
| KR20190133790A (ko) * | 2011-08-01 | 2019-12-03 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 mek 억제제를 사용하는 암 치료 방법 |
| EP2615181A1 (en) * | 2012-01-10 | 2013-07-17 | Universite Joseph Fourier - Grenoble 1 | Cyclon expression for the identification and control of cancer cells |
| SG10201700698WA (en) * | 2012-05-15 | 2017-02-27 | Bristol Myers Squibb Co | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
| EP2920325A2 (en) * | 2012-11-15 | 2015-09-23 | Bristol-Myers Squibb Company | Biomarkers for predicting clinical response of cancer patients to treatment with immunotherapeutic agent |
-
2015
- 2015-12-29 CN CN201580070110.8A patent/CN107208138A/zh active Pending
- 2015-12-29 WO PCT/US2015/067878 patent/WO2016109546A2/en not_active Ceased
- 2015-12-29 EP EP15832855.9A patent/EP3240908A2/en active Pending
- 2015-12-29 JP JP2017534648A patent/JP2018503373A/ja active Pending
-
2017
- 2017-05-31 US US15/609,473 patent/US11236394B2/en active Active
-
2021
- 2021-03-01 JP JP2021031306A patent/JP7325463B2/ja active Active
- 2021-12-17 US US17/554,966 patent/US12385098B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013505008A (ja) * | 2009-09-18 | 2013-02-14 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法 |
| WO2014023706A1 (en) * | 2012-08-06 | 2014-02-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for screening patients with a cancer |
Non-Patent Citations (8)
| Title |
|---|
| CLIN CANCER RES, vol. 15, no. 3, JPN6021029718, 2009, pages 1046 - 1051, ISSN: 0004562556 * |
| CLINICAL IMMUNOLOGY, vol. 134, JPN6021029717, 2010, pages 277 - 288, ISSN: 0004562557 * |
| GENE THERAPY, vol. 17, JPN6021029716, 2010, pages 972 - 979, ISSN: 0004562558 * |
| PLOS ONE, vol. vol.9, issue 2, JPN6022001755, February 2014 (2014-02-01), pages 89350 - 1, ISSN: 0004682948 * |
| SCIENCE, vol. 302, JPN6022001754, 2003, pages 1041 - 1043, ISSN: 0004682949 * |
| THE JOURNAL OF IMMUNOLOGY, vol. 177, JPN6022001753, 2006, pages 4330 - 4340, ISSN: 0004682950 * |
| ULTRA-LEAFTM PURIFIED ANTI-MOUSE CD8A ANTIBODY, JPN6022001752, 2014, ISSN: 0004682951 * |
| 新たな癌免疫療法:制御性T細胞制御療法, vol. 101, no. 10, JPN6019045035, 2010, pages 207 - 214, ISSN: 0004682944 * |
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| JP2021524744A (ja) * | 2018-05-21 | 2021-09-16 | ナノストリング テクノロジーズ,インコーポレイティド | 分子遺伝子シグネチャーとその使用方法 |
| JP2024053048A (ja) * | 2018-05-21 | 2024-04-12 | ナノストリング テクノロジーズ,インコーポレイティド | 分子遺伝子シグネチャーとその使用方法 |
| KR102084196B1 (ko) * | 2018-08-29 | 2020-03-03 | 연세대학교 산학협력단 | 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트 |
| WO2020045996A1 (ko) * | 2018-08-29 | 2020-03-05 | 연세대학교 산학협력단 | 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트 |
| US12480949B2 (en) | 2018-08-29 | 2025-11-25 | Industry-Academic Cooperation Foundation, Yonsei University | Methods for treating non-small lung cancer and for preparing a sample |
| JP2022511502A (ja) * | 2018-12-05 | 2022-01-31 | ジェネンテック, インコーポレイテッド | がんの免疫療法のための診断方法及び診断用組成物 |
| JP7671248B2 (ja) | 2018-12-05 | 2025-05-01 | ジェネンテック, インコーポレイテッド | がんの免疫療法のための診断方法及び診断用組成物 |
| JP2022527972A (ja) * | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
| WO2021107452A1 (ko) * | 2019-11-29 | 2021-06-03 | 의료법인 성광의료재단 | 면역 세포 치료제에 대한 치료 반응성 예측용 바이오마커 |
| JP2023504444A (ja) * | 2019-11-29 | 2023-02-03 | スンクワン メディカル ファウンデーション | 免疫治療剤に係わる治療反応性予測用バイオマーカー |
| JP2024502489A (ja) * | 2021-01-12 | 2024-01-19 | コーニンクレッカ フィリップス エヌ ヴェ | 結腸直腸がん対象者の転帰の予測 |
| WO2024225488A1 (ja) * | 2023-04-27 | 2024-10-31 | 株式会社リプロセル | 抗pd-1抗体療法に応答性である候補がん患者を同定する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3240908A2 (en) | 2017-11-08 |
| CN107208138A (zh) | 2017-09-26 |
| US12385098B2 (en) | 2025-08-12 |
| US20170260594A1 (en) | 2017-09-14 |
| WO2016109546A3 (en) | 2016-09-01 |
| US20220298576A1 (en) | 2022-09-22 |
| JP7325463B2 (ja) | 2023-08-14 |
| US11236394B2 (en) | 2022-02-01 |
| JP2021118684A (ja) | 2021-08-12 |
| WO2016109546A2 (en) | 2016-07-07 |
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