|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
EP0382781B1
(en)
|
1987-10-23 |
1993-09-29 |
Genetics Institute, Inc. |
Composition for treating cancers characterized by over-expression of the c-fms proto-oncogene
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5866114A
(en)
|
1992-06-09 |
1999-02-02 |
Chiron Corporation |
Crystallization of M-CSFα
|
|
US20020193575A1
(en)
|
1993-09-07 |
2002-12-19 |
Smithkline Beecham P.L.C. |
Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
|
|
US6972323B1
(en)
|
1997-04-01 |
2005-12-06 |
Sankyo Company, Limited |
Anti-Fas antibodies
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
AU1804499A
(en)
|
1997-12-05 |
1999-06-28 |
La Jolla Institute For Experimental Medicine |
Inhibition of tumor growth by macrophage intervention
|
|
CA2348292A1
(en)
|
1998-10-30 |
2000-05-11 |
Takeda Chemical Industries, Ltd. |
Betacellulin protein-containing preparation
|
|
PT1223980E
(pt)
|
1999-10-28 |
2003-10-31 |
Reinhold Hofbauer |
Utilizacao de inibidores de csf-1
|
|
AU1759501A
(en)
|
1999-11-08 |
2001-06-06 |
Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The |
Method of treating a viral infection using antagonists of macrophage colony stimulating factor
|
|
US7108852B2
(en)
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
US7455836B2
(en)
|
2000-05-08 |
2008-11-25 |
The University Of Melbourne |
Method of treatment and agents useful for same
|
|
US6773895B2
(en)
|
2000-09-01 |
2004-08-10 |
Boehringer Ingelheim Pharma Kg |
Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases
|
|
US7247618B2
(en)
|
2001-04-30 |
2007-07-24 |
Tripathi Rajavashisth |
Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
|
|
JP2005500034A
(ja)
|
2001-06-20 |
2005-01-06 |
プロション バイオテク リミテッド |
受容体型タンパク質チロシンキナーゼ活性化を遮断する抗体、そのスクリーニング方法、及びその使用
|
|
PT1572106E
(pt)
|
2002-11-15 |
2010-06-17 |
Novartis Vaccines & Diagnostic |
Métodos para prevenção e tratamento de metástase de cancro e perda óssea associada a metástase de cancro
|
|
US7807389B2
(en)
|
2003-03-14 |
2010-10-05 |
University Of Rochester |
Methods and compositions related to joint inflammation diseases
|
|
NZ547279A
(en)
|
2003-10-22 |
2008-04-30 |
Keck Graduate Inst |
Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy
|
|
GB0325836D0
(en)
|
2003-11-05 |
2003-12-10 |
Celltech R&D Ltd |
Biological products
|
|
WO2005070447A2
(en)
|
2004-01-21 |
2005-08-04 |
Chiron Corporation |
M-csf muteins and uses thereof
|
|
WO2005113596A2
(en)
|
2004-05-14 |
2005-12-01 |
Receptor Biologix, Inc. |
Cell surface receptor isoforms and methods of identifying and using the same
|
|
EP2479277B1
(en)
|
2004-07-22 |
2015-09-02 |
Five Prime Therapeutics, Inc. |
Use of MGD-CSF in a method of treatment of Alzheimer's disease.
|
|
WO2006076288A2
(en)
|
2005-01-11 |
2006-07-20 |
Five Prime Therapeutics, Inc. |
Dna constructs for long-term expression of intravascularly injected naked dna
|
|
ATE454455T1
(de)
|
2005-01-27 |
2010-01-15 |
Five Prime Therapeutics Inc |
Leitsequenzen zur anleitung von polypeptidsekretion und verfahren zur herstellung
|
|
US8003108B2
(en)
|
2005-05-03 |
2011-08-23 |
Amgen Inc. |
Sclerostin epitopes
|
|
EP1945662A2
(en)
|
2005-11-10 |
2008-07-23 |
Receptor Biologix, Inc. |
Methods for production of receptor and ligand isoforms
|
|
WO2007075933A2
(en)
|
2005-12-21 |
2007-07-05 |
Cell Signaling Technology, Inc. |
Translocation and mutant csf1r kinase in human leukemia
|
|
KR101358600B1
(ko)
|
2005-12-22 |
2014-02-06 |
조마 테크놀로지 리미티드 |
가용성 인간 ｍ-ｃｓｆ 수용체 및 이의 용도
|
|
US20090246208A1
(en)
|
2006-01-05 |
2009-10-01 |
Novartis Ag |
Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
|
|
HUE035654T2
(en)
|
2006-04-19 |
2018-05-28 |
Novartis Ag |
6-o-substituted benzoxazole and benzothiazole compounds and methods for inhibiting CSF-1R signaling
|
|
EP2423226A3
(en)
|
2006-11-10 |
2012-05-30 |
Amgen Inc. |
Antibody-based diagnostics and therapeutics
|
|
WO2008060610A2
(en)
|
2006-11-17 |
2008-05-22 |
Biogen Idec Ma Inc. |
Systemic administration of colony stimulating factors to treat amyloid associated disorders
|
|
DE602008004296D1
(de)
|
2007-02-14 |
2011-02-17 |
Vaccinex Inc |
Humanisierte anti-cd100-antikörper
|
|
WO2008124858A2
(en)
|
2007-04-11 |
2008-10-23 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges. M.B.H. |
Targeted receptor
|
|
ES2452349T3
(es)
|
2007-05-21 |
2014-04-01 |
Novartis Ag |
Inhibidores de CSF-1R, composiciones, y métodos de uso
|
|
US20100298217A1
(en)
|
2007-05-30 |
2010-11-25 |
Evan Richard Stanley |
Csf-1r mutants
|
|
HUE037265T2
(hu)
|
2007-08-21 |
2018-08-28 |
Amgen Inc |
Humán c-fms antigént kötõ proteinek
|
|
US7981415B2
(en)
|
2007-09-07 |
2011-07-19 |
Cisthera, Inc. |
Humanized PAI-1 antibodies
|
|
MX2010004246A
(es)
|
2007-10-18 |
2010-04-30 |
Novartis Ag |
Inhibidores de csf-1r para el tratamiento de cancer y de enfermedades oseas.
|
|
EP2215482A2
(en)
|
2007-10-31 |
2010-08-11 |
Janssen Pharmaceutica N.V. |
Biomarker for assessing response to fms treatment
|
|
WO2009075344A1
(ja)
|
2007-12-12 |
2009-06-18 |
Japan As Represented By Director General Of Agency Of National Cancer Center |
M-csf受容体を分子標的とするmll白血病及びmoz白血病治療剤、およびその利用
|
|
EP2262836B1
(en)
|
2008-03-14 |
2016-03-09 |
Transgene SA |
Antibody against the csf-1 r
|
|
US8470977B2
(en)
|
2008-03-14 |
2013-06-25 |
Transgene S.A. |
Antibody against the CSF-1R
|
|
WO2009143018A2
(en)
|
2008-05-19 |
2009-11-26 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
CA2727389A1
(en)
|
2008-06-10 |
2009-12-17 |
Prabha N. Ibrahim |
5h-pyrrolo [2,3-b] pyrazine derivatives for kinase modulation, and indications therefor
|
|
US8183207B2
(en)
|
2008-11-26 |
2012-05-22 |
Five Prime Therapeutics, Inc. |
Treatment of osteolytic disorders and cancer using CSF1R extracellular domain fusion molecules
|
|
US8080246B2
(en)
|
2008-11-26 |
2011-12-20 |
Five Prime Therapeutics, Inc. |
Colony stimulating factor 1 receptor (CSF1R) extracellular domain fusion molecules
|
|
EP2496086B1
(en)
|
2009-11-06 |
2017-05-31 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
RS58693B1
(sr)
|
2009-12-10 |
2019-06-28 |
Hoffmann La Roche |
Antitela koja poželjno vezuju ekstracelularni domen 4 humanog csf1r, i njihova primena
|
|
HRP20140770T1
(hr)
|
2009-12-21 |
2014-11-07 |
Array Biopharma, Inc. |
SUPSTITUIRANI SPOJEVI N-(1H-INDAZOL-4-IL)IMIDAZO[1,2-a]PIRIDIN-3-KARBOKSAMIDA KAO INHIBITORI CFMS
|
|
CN102918060B
(zh)
|
2010-03-05 |
2016-04-06 |
霍夫曼-拉罗奇有限公司 |
抗人csf-1r抗体及其用途
|
|
BR112012022046A2
(pt)
|
2010-03-05 |
2017-02-14 |
F Hoffamann-La Roche Ag |
''anticorpo,composição farmacêutica,ácido nucleico ,vetores de expressão,célula hospedeira e método para a produção de um anticorpo recombinante''.
|
|
AR080698A1
(es)
|
2010-04-01 |
2012-05-02 |
Imclone Llc |
Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e
|
|
SG10201911345WA
(en)
|
2010-05-04 |
2020-01-30 |
Five Prime Therapeutics Inc |
Antibodies that bind csf1r
|
|
AR084234A1
(es)
|
2010-12-13 |
2013-05-02 |
Novartis Ag |
Metodos predictivos y metodos para tratar artritis usando antagonistas de interleuquina 17 (il-17)
|
|
RU2639553C2
(ru)
|
2011-10-21 |
2017-12-21 |
Трансжене Са |
Модуляция активации макрофагов
|
|
EP2768861A1
(en)
|
2011-10-21 |
2014-08-27 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
A m-dc8+ monocyte depleting agent for the prevention or the treatment of a condition associated with a chronic hyperactivation of the immune system
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
AU2013238126C1
(en)
*
|
2012-03-26 |
2018-06-14 |
Nippon Chemiphar Co., Ltd. |
Prophylactic or therapeutic agent for giant cell tumors occurring in bone and soft tissue or for chondrosarcoma
|
|
US20130302322A1
(en)
|
2012-05-11 |
2013-11-14 |
Five Prime Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
|
|
AU2012374617B2
(en)
|
2012-05-11 |
2015-09-17 |
Five Prime Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R)
|
|
CN104684582A
(zh)
|
2012-08-31 |
2015-06-03 |
戊瑞治疗有限公司 |
用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法
|