HK1245804A1 - 用於治疗pvns的抗csf1r抗体 - Google Patents

用於治疗pvns的抗csf1r抗体 Download PDF

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Publication number
HK1245804A1
HK1245804A1 HK18105046.3A HK18105046A HK1245804A1 HK 1245804 A1 HK1245804 A1 HK 1245804A1 HK 18105046 A HK18105046 A HK 18105046A HK 1245804 A1 HK1245804 A1 HK 1245804A1
Authority
HK
Hong Kong
Prior art keywords
pvns
csf1r antibodies
treating
csf1r
antibodies
Prior art date
Application number
HK18105046.3A
Other languages
English (en)
Chinese (zh)
Inventor
Robert Sikorski
Julie Hambleton
Nilacantan SANKAR
Original Assignee
Five Prime Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics, Inc. filed Critical Five Prime Therapeutics, Inc.
Publication of HK1245804A1 publication Critical patent/HK1245804A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK18105046.3A 2014-12-22 2015-12-21 用於治疗pvns的抗csf1r抗体 HK1245804A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462095297P 2014-12-22 2014-12-22
US201462095297P 2014-12-22
US201562163251P 2015-05-18 2015-05-18
US201562163251P 2015-05-18
PCT/US2015/067012 WO2016106180A1 (en) 2014-12-22 2015-12-21 Anti-csf1r antibodies for treating pvns

Publications (1)

Publication Number Publication Date
HK1245804A1 true HK1245804A1 (zh) 2018-08-31

Family

ID=55135539

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105046.3A HK1245804A1 (zh) 2014-12-22 2015-12-21 用於治疗pvns的抗csf1r抗体

Country Status (16)

Country Link
US (3) US10040858B2 (enExample)
EP (1) EP3237447B1 (enExample)
JP (1) JP6797801B2 (enExample)
KR (1) KR20170096187A (enExample)
CN (1) CN107257806B (enExample)
AU (1) AU2015369854B2 (enExample)
BR (1) BR112017013111A2 (enExample)
CA (1) CA2969341C (enExample)
EA (1) EA201791421A1 (enExample)
ES (1) ES2843586T3 (enExample)
HK (1) HK1245804A1 (enExample)
IL (1) IL252716A0 (enExample)
MX (1) MX2017008218A (enExample)
SG (1) SG11201704792UA (enExample)
TW (1) TW201630937A (enExample)
WO (1) WO2016106180A1 (enExample)

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Publication number Publication date
ES2843586T3 (es) 2021-07-19
AU2015369854A1 (en) 2017-06-15
AU2015369854B2 (en) 2021-07-01
US10040858B2 (en) 2018-08-07
KR20170096187A (ko) 2017-08-23
IL252716A0 (en) 2017-08-31
US10730949B2 (en) 2020-08-04
EP3237447A1 (en) 2017-11-01
EA201791421A1 (ru) 2017-10-31
CN107257806B (zh) 2021-08-10
US20190119390A1 (en) 2019-04-25
MX2017008218A (es) 2017-10-18
WO2016106180A1 (en) 2016-06-30
TW201630937A (zh) 2016-09-01
CA2969341A1 (en) 2016-06-30
CA2969341C (en) 2023-07-04
BR112017013111A2 (pt) 2018-05-15
US20160185869A1 (en) 2016-06-30
EP3237447B1 (en) 2020-12-02
JP2018501254A (ja) 2018-01-18
US20210009700A1 (en) 2021-01-14
JP6797801B2 (ja) 2020-12-09
SG11201704792UA (en) 2017-07-28
CN107257806A (zh) 2017-10-17

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