|
US3541130A
(en)
|
1967-02-06 |
1970-11-17 |
Boehringer Sohn Ingelheim |
1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
|
|
US4613676A
(en)
*
|
1983-11-23 |
1986-09-23 |
Ciba-Geigy Corporation |
Substituted 5-amino-4-hydroxyvaleryl derivatives
|
|
US4743607A
(en)
|
1987-05-29 |
1988-05-10 |
Merrell Dow Pharmaceuticals Inc. |
Cardiotonic tricyclic imidazolones
|
|
JPH04503205A
(ja)
|
1988-05-02 |
1992-06-11 |
ナフッチィ，エヌ，エリック |
神経学的活性化合物
|
|
US5028622A
(en)
|
1988-05-06 |
1991-07-02 |
Ajinomoto Company, Inc. |
Administration of amino acids as treatment for neurodegenerative disorders
|
|
US5321029A
(en)
|
1988-11-14 |
1994-06-14 |
Beecham-Wuelfing Gmbh & Co.K.G. |
Xanthines
|
|
CA2010531A1
(en)
*
|
1989-03-06 |
1990-09-06 |
Werner Neidhart |
Amino acid derivatives
|
|
EP0536671B1
(de)
|
1991-10-07 |
1996-03-06 |
Hoechst Aktiengesellschaft |
Carbonsäureester-Schutzgruppen, ein Verfahren zu ihrer Herstellung, ihre Kopplung an eine funktionelle Gruppe sowie ihre Verwendung
|
|
US5608067A
(en)
|
1993-12-09 |
1997-03-04 |
Afonso; Adriano |
4-substituted pyrazoloquinoline derivatives
|
|
GB9402331D0
(en)
|
1994-02-07 |
1994-03-30 |
Univ Mcgill |
Nerve growth factor structural analogs and their uses
|
|
JPH08119922A
(ja)
|
1994-10-21 |
1996-05-14 |
Torii Yakuhin Kk |
ｏ−ピバロイル−チロシン誘導体
|
|
WO1996016980A1
(en)
|
1994-11-29 |
1996-06-06 |
Novartis Ag |
Morpholinoethylamide derivatives
|
|
JPH1081661A
(ja)
|
1995-10-23 |
1998-03-31 |
Sankyo Co Ltd |
ヒドロキサム酸誘導体
|
|
DE69736976T2
(de)
|
1996-03-29 |
2007-10-18 |
Trustees Of Boston University, Boston |
Mit Alzheimer Krankheit verknüpften Verfahren zur Diagnose, zur Herstellung von Medikamenten und zum Screenen von Substanzen sowie aus Beta-Amyloid abgeleiteten Peptiden
|
|
US5958875A
(en)
|
1996-03-29 |
1999-09-28 |
The Regents Of The University Of California |
Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity
|
|
AU2645497A
(en)
|
1996-05-06 |
1997-11-26 |
Zeneca Limited |
Thio derivatives of hydroxamic acids
|
|
GB9613547D0
(en)
|
1996-06-27 |
1996-08-28 |
Pharmacia Spa |
Matrix metalloproteinase inhibitors
|
|
GB9616105D0
(en)
|
1996-07-31 |
1996-09-11 |
Univ Kingston |
TrkA binding site of NGF
|
|
GB9715962D0
(en)
|
1996-08-23 |
1997-10-01 |
Zeneca Ltd |
Sulfonamides
|
|
SK286779B6
(sk)
|
1997-02-19 |
2009-05-07 |
Berlex Laboratories, Inc. |
N-Heterocyklické deriváty ako inhibítory NOS, spôsob ich prípravy, farmaceutické prostriedky s ich obsahom a ich použitie
|
|
FR2762315B1
(fr)
|
1997-04-22 |
1999-05-28 |
Logeais Labor Jacques |
Derives d'amino-acides inhibiteurs des metalloproteases de la matrice extracellulaire et de la liberation du tnf alpha
|
|
US6117841A
(en)
|
1997-05-30 |
2000-09-12 |
Warner-Lambert Company |
Substituted peptidylamine calcium channel blockers
|
|
US6342507B1
(en)
|
1997-09-05 |
2002-01-29 |
Isotechnika, Inc. |
Deuterated rapamycin compounds, method and uses thereof
|
|
US20020022657A1
(en)
*
|
1998-02-11 |
2002-02-21 |
Francine Gervais |
Methods for modulating neuronal cell death
|
|
WO1999050264A1
(en)
|
1998-03-30 |
1999-10-07 |
Kyowa Hakko Kogyo Co., Ltd. |
Quinazoline derivatives
|
|
FR2783519B1
(fr)
|
1998-09-23 |
2003-01-24 |
Sod Conseils Rech Applic |
Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
|
|
JP2002529404A
(ja)
|
1998-11-06 |
2002-09-10 |
ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
基質メタロプロテアーゼ関連疾患の治療薬としてのシスチン誘導体
|
|
US6472418B1
(en)
|
1998-12-18 |
2002-10-29 |
Warner-Lambert Company |
Non-peptide NK1 receptors antagonists
|
|
US6583148B1
(en)
|
1999-04-08 |
2003-06-24 |
Krenitsky Pharmaceuticals, Inc. |
Neurotrophic substituted pyrimidines
|
|
US6492380B1
(en)
|
1999-05-17 |
2002-12-10 |
Queen's University At Kingston |
Method of inhibiting neurotrophin-receptor binding
|
|
TWI289557B
(en)
|
1999-06-17 |
2007-11-11 |
Takeda Chemical Industries Ltd |
A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
|
|
US6858577B1
(en)
|
1999-06-29 |
2005-02-22 |
Ortho-Mcneil Pharmaceutical, Inc. |
Indole peptidomimetics as thrombin receptor antagonists
|
|
DE19939910A1
(de)
|
1999-08-23 |
2001-03-01 |
Morphochem Ag |
Neue Verbindungen, die Tryptase-Aktivität hemmen
|
|
WO2001017953A1
(en)
|
1999-09-08 |
2001-03-15 |
Guilford Pharmaceuticals Inc. |
Non-peptidic cyclophilin binding compounds and their use
|
|
KR100708247B1
(ko)
|
1999-12-08 |
2007-04-16 |
데이진 가부시키가이샤 |
고리형 아민 ｃｃｒ５ 리셉터 길항제
|
|
ATE340571T1
(de)
|
2000-01-18 |
2006-10-15 |
Univ Mcgill |
Pharmazeutische zubereitungen enthaltend beta- turn peptidomimetische zyklische substanzen
|
|
AR028606A1
(es)
|
2000-05-24 |
2003-05-14 |
Smithkline Beecham Corp |
Nuevos inhibidores de mmp-2/mmp-9
|
|
US6699989B1
(en)
|
2000-08-28 |
2004-03-02 |
B. Vithal Shetty |
Antiviral and antimicrobial guanidine or biguanidine derivatives
|
|
AU2002220144A1
(en)
*
|
2000-12-13 |
2002-06-24 |
Spelman College |
Multiplex coherent raman spectroscopy detector and method
|
|
MXPA04000334A
(es)
|
2001-07-11 |
2004-09-28 |
Elan Pharm Inc |
Compuestos de alquilamida n-(3-amino-2-hidroxi-propil) substituidos.
|
|
US20040248984A1
(en)
|
2001-08-29 |
2004-12-09 |
Josef Krieglstein |
Use of $g(b)-adrenoceptor agonists for the treatment of neurodegenerative diseases
|
|
AU2002335824A1
(en)
|
2001-10-12 |
2003-04-22 |
Case Western Reserve University |
Neuronal regeneration
|
|
IL161881A0
(en)
|
2001-11-08 |
2005-11-20 |
Upjohn Co |
N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives
|
|
US7439251B2
(en)
*
|
2002-05-03 |
2008-10-21 |
Israel Institute For Biological Research |
Methods and compositions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor
|
|
UA77526C2
(en)
|
2002-06-07 |
2006-12-15 |
Sanofi Aventis |
Substituted derivatives of 1-piperazineacylpiperidine, a method for the preparation thereof and their use in therapy
|
|
US7429560B2
(en)
|
2002-09-25 |
2008-09-30 |
Georgia Tech Research Corporation |
Ketoamide inhibitors in chronic nerve disease
|
|
WO2004031145A2
(en)
|
2002-10-02 |
2004-04-15 |
Bristol-Myers Squibb Company |
Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor xa inhibitors
|
|
US20040186044A1
(en)
|
2002-11-06 |
2004-09-23 |
Cosgaya Jose Miguel |
Modulation of myelination by interaction with P75 and TRK receptors
|
|
US20040167183A1
(en)
|
2003-02-20 |
2004-08-26 |
The Procter & Gamble Company |
Phenethylamino sulfamic acids
|
|
GB0304433D0
(en)
|
2003-02-27 |
2003-04-02 |
Xceleron Ltd |
Improvements relating to chemical libraries
|
|
WO2005044810A1
(en)
|
2003-10-30 |
2005-05-19 |
Janssen Pharmaceutica, N.V. |
Glyt2 modulators
|
|
DK1689721T3
(da)
|
2003-11-26 |
2010-09-20 |
Pfizer Prod Inc |
Aminopyrazolderivater som GSK-3-ihibitorer
|
|
JP2007522129A
(ja)
|
2004-01-21 |
2007-08-09 |
エラン ファーマシューティカルズ，インコーポレイテッド |
アスパラギン酸プロテアーゼ阻害薬を用いるアミロイドーシスの処置方法
|
|
EP1736465A4
(en)
|
2004-03-31 |
2009-06-17 |
Ajinomoto Kk |
ANILINE DERIVATIVES
|
|
EP1768955A1
(en)
|
2004-07-12 |
2007-04-04 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Amide derivatives as inhibitors of histone deacetylase
|
|
JP4194540B2
(ja)
|
2004-07-27 |
2008-12-10 |
キヤノン株式会社 |
画像形成装置
|
|
US20110230479A1
(en)
|
2005-04-15 |
2011-09-22 |
Longo Frank M |
Neurotrophin mimetics and uses thereof
|
|
US7723328B2
(en)
|
2005-04-15 |
2010-05-25 |
The University Of North Carolina At Chapel Hill |
Methods of facilitating cell survival using neurotrophin mimetics
|
|
US8686045B2
(en)
|
2005-06-08 |
2014-04-01 |
The University Of North Carolina At Chapel Hill |
Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics
|
|
ES2436225T3
(es)
|
2005-12-22 |
2013-12-27 |
Hydra Biosciences, Inc. |
Inhibidores TRPA1 para tratamiento del dolor
|
|
WO2008107365A1
(en)
*
|
2007-03-02 |
2008-09-12 |
Medivir Ab |
New compounds
|
|
JP2012519703A
(ja)
|
2009-03-06 |
2012-08-30 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
ニューロトロフィン・ミメティック及びその使用
|
|
CN102740856B
(zh)
|
2009-11-12 |
2015-02-18 |
特罗菲克斯制药股份有限公司 |
神经营养蛋白模拟化合物及其盐的晶型
|
|
US10273219B2
(en)
|
2009-11-12 |
2019-04-30 |
Pharmatrophix, Inc. |
Crystalline forms of neurotrophin mimetic compounds and their salts
|
|
WO2011066544A2
(en)
|
2009-11-30 |
2011-06-03 |
Pharmatrophix, Inc. |
Deuterated compounds useful for treating neurodegenerative diseases
|
|
EP2900646A4
(en)
|
2012-09-27 |
2016-09-21 |
Pharmatrophix Inc |
CRYSTALLINE FORMS OF NEUROTROPHINMIMETIC COMPOUNDS AND THEIR SALTS
|