JP2018035162A5 - - Google Patents

Download PDF

Info

Publication number
JP2018035162A5
JP2018035162A5 JP2017172825A JP2017172825A JP2018035162A5 JP 2018035162 A5 JP2018035162 A5 JP 2018035162A5 JP 2017172825 A JP2017172825 A JP 2017172825A JP 2017172825 A JP2017172825 A JP 2017172825A JP 2018035162 A5 JP2018035162 A5 JP 2018035162A5
Authority
JP
Japan
Prior art keywords
therapeutic agent
superoxide dismutase
agent according
administered
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017172825A
Other languages
English (en)
Japanese (ja)
Other versions
JP6382416B2 (ja
JP2018035162A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2018035162A publication Critical patent/JP2018035162A/ja
Publication of JP2018035162A5 publication Critical patent/JP2018035162A5/ja
Application granted granted Critical
Publication of JP6382416B2 publication Critical patent/JP6382416B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017172825A 2011-09-26 2017-09-08 疾患の治療方法 Active JP6382416B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161539365P 2011-09-26 2011-09-26
US61/539,365 2011-09-26

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014532075A Division JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018145207A Division JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法

Publications (3)

Publication Number Publication Date
JP2018035162A JP2018035162A (ja) 2018-03-08
JP2018035162A5 true JP2018035162A5 (enExample) 2018-08-02
JP6382416B2 JP6382416B2 (ja) 2018-08-29

Family

ID=47911939

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2014532075A Active JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法
JP2017172825A Active JP6382416B2 (ja) 2011-09-26 2017-09-08 疾患の治療方法
JP2018145207A Active JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法
JP2020121417A Active JP7562125B2 (ja) 2011-09-26 2020-07-15 疾患の治療方法
JP2022200192A Active JP7697688B2 (ja) 2011-09-26 2022-12-15 疾患の治療方法
JP2025094341A Pending JP2025131753A (ja) 2011-09-26 2025-06-05 疾患の治療方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2014532075A Active JP6267638B2 (ja) 2011-09-26 2012-09-24 疾患の治療方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018145207A Active JP6736618B2 (ja) 2011-09-26 2018-08-01 疾患の治療方法
JP2020121417A Active JP7562125B2 (ja) 2011-09-26 2020-07-15 疾患の治療方法
JP2022200192A Active JP7697688B2 (ja) 2011-09-26 2022-12-15 疾患の治療方法
JP2025094341A Pending JP2025131753A (ja) 2011-09-26 2025-06-05 疾患の治療方法

Country Status (8)

Country Link
US (5) US9149483B2 (enExample)
EP (1) EP2760874A4 (enExample)
JP (6) JP6267638B2 (enExample)
CN (2) CN111467351A (enExample)
AU (5) AU2012316397B2 (enExample)
CA (2) CA2849456C (enExample)
HK (1) HK1199261A1 (enExample)
WO (1) WO2013048965A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2056675T3 (pl) 2006-10-12 2019-08-30 Galera Labs, Llc Metody leczenia zapalenia błony śluzowej jamy ustnej
AU2012316397B2 (en) * 2011-09-26 2016-07-21 Galera Labs, Llc Methods for treatment of diseases
TWI746449B (zh) * 2015-07-20 2021-11-21 美商Ａｉ治療公司 使用阿吡莫德治療癌症之方法
US10597415B2 (en) 2015-08-11 2020-03-24 Galera Labs, Llc Pentaaza macrocyclic ring complexes possessing oral bioavailability
WO2017192740A2 (en) * 2016-05-03 2017-11-09 Galera Labs, Llc Combination therapy for cancer treatment
CA3035766A1 (en) 2016-09-01 2018-03-08 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound
JP2020507598A (ja) * 2017-02-15 2020-03-12 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ 局所腸送達のためのペンタアザマクロ環錯体
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
AU2019215032A1 (en) * 2018-01-31 2020-09-10 Board Of Regents Of The University Of Texas System Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
EP4041253A4 (en) * 2019-10-10 2023-11-01 Galera Labs, LLC PRODUCTION PROCESS FOR AQUEOUS FORMULATION OF A COORDINATION COMPLEX CONTAINING MANGANESE, FORMULATION AND TREATMENT PROCESS
WO2021163397A1 (en) * 2020-02-13 2021-08-19 Teva Pharmaceuticals International Gmbh Solid state forms of avasopasem manganese and process for preparation thereof

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001212A (en) 1973-10-03 1977-01-04 E. I. Du Pont De Nemours And Company Macrocyclic polyamines
US3930867A (en) 1974-01-07 1976-01-06 E. I. Du Pont De Nemours And Company Macrocyclic polyamines as sensitizers for silver halide emulsions
JPS61226751A (ja) 1985-03-30 1986-10-08 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料用処理液及びその処理方法
US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
US5033252A (en) 1987-12-23 1991-07-23 Entravision, Inc. Method of packaging and sterilizing a pharmaceutical product
US5096724A (en) 1988-06-03 1992-03-17 Aquanautics Corporation Methods, compositions, and systems for ligand extraction
GB9001245D0 (en) 1990-01-19 1990-03-21 Salutar Inc Compounds
CA2072934C (en) 1991-07-19 2007-08-28 Karl William Aston Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
DE69224839T2 (de) 1991-07-19 1998-10-08 Monsanto Co Mangan-Komplexe mit Stickstoff enthaltenden makrozyklischen Liganden, wirksam als Superoxiddismutasekatalysatoren.
US5323907A (en) 1992-06-23 1994-06-28 Multi-Comp, Inc. Child resistant package assembly for dispensing pharmaceutical medications
US6204259B1 (en) 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
NZ283279A (en) 1994-04-22 1998-01-26 Monsanto Co Magnetic resonance imaging compounds comprising paramagnetic metals, compositions and use thereof
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
JPH0840941A (ja) 1994-07-29 1996-02-13 Kanegafuchi Chem Ind Co Ltd 炎症性腸疾患治療製剤
US6525041B1 (en) 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
CA2229799A1 (en) * 1995-08-17 1997-02-27 Monsanto Company Bioconjugates of manganese complexes and their application as catalysts
US5976498A (en) 1995-08-17 1999-11-02 Neumann; William L. Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands
CA2229781A1 (en) 1995-08-17 1997-02-27 Monsanto Company Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
US20020128248A1 (en) 1997-06-20 2002-09-12 Metaphore Pharmaceuticals, Inc SODm therapy for prevention and/or treatment of inflammatory disease
US6180620B1 (en) * 1997-06-20 2001-01-30 G.D. Searle & Co. Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals
US20050171198A1 (en) 1997-06-20 2005-08-04 Metaphore Pharmaceuticals, Inc. SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease
US20060270639A1 (en) 1997-06-20 2006-11-30 Daniela Salvemini Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs
US6214817B1 (en) * 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
JP2991172B2 (ja) 1997-10-24 1999-12-20 日本電気株式会社 半導体装置
EP1045851B1 (en) 1997-11-03 2003-04-23 Duke University Substituted porphyrins
GB9817845D0 (en) 1998-08-17 1998-10-14 Glaxo Group Ltd Chemical compounds
US6040330A (en) 1999-01-08 2000-03-21 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of taxanes
DE60037768T2 (de) * 1999-05-27 2009-01-15 Pharmacia Corp.(N.D.Ges.D.Staates Delaware) Biomaterialien, modifiziert mit Superoxid-Dismutase Imitatoren
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
JP2003502372A (ja) 1999-06-23 2003-01-21 エリック・エフ・バーンスタイン 創傷治癒および光傷害の防止におけるニトロキシドの使用
WO2001058458A1 (en) 2000-02-08 2001-08-16 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
US7279160B2 (en) 2000-05-02 2007-10-09 The Uab Research Foundation Combinations of DR5 antibodies and other therapeutic agents
AU2000265525A1 (en) 2000-08-29 2002-03-13 Mepha Ag Medicament for treating intestinal diseases
US6589948B1 (en) * 2000-11-28 2003-07-08 Eukarion, Inc. Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases
US7166910B2 (en) 2000-11-28 2007-01-23 Knowles Electronics Llc Miniature silicon condenser microphone
US20020072512A1 (en) 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
ATE464061T1 (de) * 2001-01-05 2010-04-15 Metaphore Pharmaceuticals Inc Zusammensetzungen und verfahren zur erhöhung der zytokin-aktivität und zur behandlung der hypotension assoziiert mit der verabreichung von zytokinen
CA2436245C (en) * 2001-01-19 2013-04-23 National Jewish Medical And Research Center Medicament for protection in radiotherapy
AU2002236861A1 (en) 2001-01-26 2002-08-06 Metaphore Pharmaceuticals, Inc. Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes
CA2439971A1 (en) 2001-03-02 2002-09-12 Metaphore Pharmaceuticals, Inc. Chromatography of metal complexes
US20040137638A1 (en) * 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
WO2002100395A1 (en) 2001-06-08 2002-12-19 Genzyme Corporation Bismuth salts of anti-oxidants and radical scavengers for prevention and treatment of mucous membrane ulcers
US20040132706A1 (en) 2001-10-05 2004-07-08 Daniela Salvemini Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension
CN100506277C (zh) 2001-11-01 2009-07-01 Uab研究基金会 肿瘤坏死因子相关细胞凋亡诱导配体受体的选择性抗体和其它治疗剂的联合体系
SI1463563T1 (sl) * 2001-12-14 2009-06-30 Alcon Inc Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni
WO2003088986A1 (en) 2002-04-16 2003-10-30 Isis Innovation Limited Curcumin for the prevention and/or treatment of tissue damage
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
US6781231B2 (en) 2002-09-10 2004-08-24 Knowles Electronics Llc Microelectromechanical system package with environmental and interference shield
US6798047B1 (en) 2002-12-26 2004-09-28 Amkor Technology, Inc. Pre-molded leadframe
WO2005042718A2 (en) 2003-10-31 2005-05-12 Metaphore Pharmaceuticals, Inc. Compositions and methods for treating, preventing, reversing and inhibiting pain
FR2863892B1 (fr) 2003-12-18 2007-05-11 Univ Paris Descartes Utilisation de mimetiques de la superoxyde dismutase et de la glutathion reductase comme anti-cancereux
WO2005070126A2 (en) 2004-01-08 2005-08-04 The Regents Of The University Of Colorado Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
EA010834B1 (ru) 2004-03-29 2008-12-30 Инотек Фармасьютикалз Корпорейшн Пиридилзамещённые порфириновые соединения и способы их применения
US7262498B2 (en) 2004-10-19 2007-08-28 Hewlett-Packard Development Company, L.P. Assembly with a ring and bonding pads formed of a same material on a substrate
US20070148154A1 (en) 2004-12-17 2007-06-28 Universite Rene Descartes (Paris V) Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs
US8217166B2 (en) 2005-05-05 2012-07-10 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
WO2006083508A2 (en) 2005-01-10 2006-08-10 Metaphore Pharmaceuticals Inc. Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs
WO2006078713A2 (en) 2005-01-19 2006-07-27 Metaphore Pharmaceuticals, Inc. Methotrexate combinations for treating inflammatory diseases
AU2006230292A1 (en) 2005-03-31 2006-10-05 Schering Corporation Spirocyclic thrombin receptor antagonists
CN2870352Y (zh) 2005-12-23 2007-02-14 瑞声声学科技(深圳)有限公司 微机电系统传声器扣合式封装结构
US20100158857A1 (en) 2006-05-23 2010-06-24 University Of Utah Research Foundation Compositions and methods for the inhibition of endothelial nitric oxide synthase activity
US20080139525A1 (en) 2006-08-31 2008-06-12 The Brigham And Women's Hospital, Inc. Antioxidant therapies
US20080161324A1 (en) 2006-09-14 2008-07-03 Johansen Lisa M Compositions and methods for treatment of viral diseases
PL2056675T3 (pl) * 2006-10-12 2019-08-30 Galera Labs, Llc Metody leczenia zapalenia błony śluzowej jamy ustnej
TWI333264B (en) 2007-01-10 2010-11-11 Advanced Semiconductor Eng Packaging structure and method of mems microphone
US20100184679A1 (en) * 2007-09-11 2010-07-22 Dorian Bevec Use of a combination of cart peptides as a therapeutic agent
US20090221622A1 (en) 2008-02-29 2009-09-03 Eagle Pharmaceuticals, Inc. Topotecan ready to use solutions
AU2009241514A1 (en) 2008-04-15 2009-11-05 Intermune, Inc. Novel inhibitors of hepatitis C virus replication
CA2724550C (en) * 2008-05-22 2017-01-03 Kereos, Inc. Combination antitumor therapy
CN102822198B (zh) 2010-03-12 2016-08-31 艾伯维生物医疗股份有限公司 Ctla4蛋白和其用途
US20120207687A1 (en) 2011-01-14 2012-08-16 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Topical formulations of targeted nitroxide agents
AU2012316397B2 (en) * 2011-09-26 2016-07-21 Galera Labs, Llc Methods for treatment of diseases
US9238659B2 (en) 2012-11-19 2016-01-19 The University Of Hong Kong Method of using binuclear gold (I) compounds for cancer treatment
US10597415B2 (en) 2015-08-11 2020-03-24 Galera Labs, Llc Pentaaza macrocyclic ring complexes possessing oral bioavailability
WO2017192740A2 (en) 2016-05-03 2017-11-09 Galera Labs, Llc Combination therapy for cancer treatment
CA3035766A1 (en) 2016-09-01 2018-03-08 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound
US20190350867A1 (en) 2016-12-27 2019-11-21 Soon Kap Hahn Prevention of local tumor recurrence following surgery using sustained and/or delayed release of medicaments contained in micro-particles
JP2020507598A (ja) 2017-02-15 2020-03-12 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ 局所腸送達のためのペンタアザマクロ環錯体
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
EP3388082A1 (en) 2017-04-13 2018-10-17 Galera Labs, LLC Combination cancer immunotherapy with pentaaza macrocyclic ring complex
WO2018191676A1 (en) 2017-04-13 2018-10-18 Galera Labs, Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
AU2019215032A1 (en) 2018-01-31 2020-09-10 Board Of Regents Of The University Of Texas System Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent

Similar Documents

Publication Publication Date Title
JP2018035162A5 (enExample)
JP2018184465A5 (enExample)
Rejhová et al. Natural compounds and combination therapy in colorectal cancer treatment
JP2020183416A5 (enExample)
JP2014526562A5 (enExample)
CN105452258B (zh) 使用双核金(i)化合物用于癌症治疗的方法
JP2015524444A5 (enExample)
JP2011503111A5 (ja) ４−ヨード−３−ニトロベンズアミド化合物と抗腫瘍剤の組み合わせによる乳がんの治療
JP2016528162A5 (enExample)
JP2015523397A5 (enExample)
JP2018533589A5 (enExample)
JP2016527202A5 (enExample)
JP2020523356A5 (enExample)
JP2019508476A5 (enExample)
JP2017537124A5 (enExample)
JP2014508758A5 (enExample)
JP2014512355A5 (enExample)
Sugawara et al. Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer: NJLCG 0601
RU2020122083A (ru) Способ снижения ототоксичности у педиатрических пациентов, получающих химиотерапию препаратами платины
TW201141472A (en) Method to treat small cell lung cancer
JP2019513706A5 (enExample)
Karpuz et al. Clinical applications of nanosized drug-delivery systems in lung cancer imaging and therapy
RU2015139515A (ru) Комбинированное лечение
JP2025015727A (ja) ｐ－ボロノフェニルアラニンを含有する注射液剤
JP2018516964A (ja) 局所進行性または転移性である肝内もしくは肝外胆管または胆嚢のカルシノーマに罹患する患者を治療する方法