BR9610241A - Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio - Google Patents

Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio

Info

Publication number
BR9610241A
BR9610241A BR9610241A BR9610241A BR9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A
Authority
BR
Brazil
Prior art keywords
bioconjugates
processes
image analysis
metal complexes
containing nitrogen
Prior art date
Application number
BR9610241A
Other languages
English (en)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR9610241A publication Critical patent/BR9610241A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR9610241A 1995-08-17 1996-08-16 Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio BR9610241A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US239495P 1995-08-17 1995-08-17
PCT/US1996/013044 WO1997006830A1 (en) 1995-08-17 1996-08-16 Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands

Publications (1)

Publication Number Publication Date
BR9610241A true BR9610241A (pt) 1999-06-29

Family

ID=21700561

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610241A BR9610241A (pt) 1995-08-17 1996-08-16 Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio

Country Status (8)

Country Link
US (3) US20040057904A1 (pt)
EP (1) EP0846003A1 (pt)
JP (1) JPH11511168A (pt)
AU (1) AU6896796A (pt)
BR (1) BR9610241A (pt)
CA (1) CA2229781A1 (pt)
NO (1) NO980647L (pt)
WO (1) WO1997006830A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006830A1 (en) * 1995-08-17 1997-02-27 Monsanto Company Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
DK1155019T3 (da) 1999-01-25 2006-04-18 Nat Jewish Med & Res Center Substituerede porphyriner og deres terapeutiske anvendelse
ATE291446T1 (de) 1999-05-27 2005-04-15 Monsanto Co Biomaterialien, modifiziert mit superoxid- dismutase imitatoren
EP2988125B1 (en) * 2001-03-02 2019-05-08 Galera Labs, LLC Manganese(ii) pentaazacycloalkane complexes
US20040137638A1 (en) 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
EP1439842A4 (en) 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
HUE044234T2 (hu) 2006-10-12 2019-10-28 Galera Labs Llc Eljárások szájnyálkahártya-gyulladás kezelésére
ES2600469T3 (es) 2008-05-23 2017-02-09 National Jewish Health Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro
US20110105417A1 (en) * 2008-06-26 2011-05-05 The Curators Of The University Of Missouri Drug Conjugates
WO2013048965A1 (en) 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases
ES2807528T3 (es) 2015-08-11 2021-02-23 Galera Labs Llc Complejos macrocíclicos pentaaza que poseen biodisponibilidad oral
EA201992431A1 (ru) 2017-10-13 2020-03-13 ГАЛЕРА ЛЭБЗ, ЭлЭлСи Комбинированная иммунотерапия рака с использованием пента-аза-макроциклического кольцевого комплекса

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Also Published As

Publication number Publication date
NO980647L (no) 1998-04-03
AU6896796A (en) 1997-03-12
US7407645B2 (en) 2008-08-05
JPH11511168A (ja) 1999-09-28
US20040057904A1 (en) 2004-03-25
CA2229781A1 (en) 1997-02-27
EP0846003A1 (en) 1998-06-10
US20090098047A1 (en) 2009-04-16
NO980647D0 (no) 1998-02-16
WO1997006830A1 (en) 1997-02-27
US20040131550A1 (en) 2004-07-08

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