JP2017536813A5 - - Google Patents
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- JP2017536813A5 JP2017536813A5 JP2017521095A JP2017521095A JP2017536813A5 JP 2017536813 A5 JP2017536813 A5 JP 2017536813A5 JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017536813 A5 JP2017536813 A5 JP 2017536813A5
- Authority
- JP
- Japan
- Prior art keywords
- primer
- virus
- reverse
- cdna
- forward primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000523 sample Substances 0.000 claims 24
- 238000000034 method Methods 0.000 claims 19
- 108091033319 polynucleotide Proteins 0.000 claims 15
- 239000002157 polynucleotide Substances 0.000 claims 15
- 102000040430 polynucleotide Human genes 0.000 claims 15
- 239000002299 complementary DNA Substances 0.000 claims 13
- 238000001514 detection method Methods 0.000 claims 13
- 102000004190 Enzymes Human genes 0.000 claims 10
- 108090000790 Enzymes Proteins 0.000 claims 10
- 102000004594 DNA Polymerase I Human genes 0.000 claims 9
- 108010017826 DNA Polymerase I Proteins 0.000 claims 9
- 102100034343 Integrase Human genes 0.000 claims 9
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 9
- 241001493065 dsRNA viruses Species 0.000 claims 8
- 108091093088 Amplicon Proteins 0.000 claims 7
- 230000003321 amplification Effects 0.000 claims 6
- 238000006073 displacement reaction Methods 0.000 claims 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims 6
- 241000725619 Dengue virus Species 0.000 claims 5
- 238000006243 chemical reaction Methods 0.000 claims 5
- 230000003612 virological effect Effects 0.000 claims 5
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 238000011901 isothermal amplification Methods 0.000 claims 4
- 239000002751 oligonucleotide probe Substances 0.000 claims 4
- 241000713196 Influenza B virus Species 0.000 claims 3
- 238000010804 cDNA synthesis Methods 0.000 claims 3
- 230000000087 stabilizing effect Effects 0.000 claims 3
- 241000712891 Arenavirus Species 0.000 claims 2
- 241000710780 Bovine viral diarrhea virus 1 Species 0.000 claims 2
- 241001115402 Ebolavirus Species 0.000 claims 2
- 241000710831 Flavivirus Species 0.000 claims 2
- 241000712902 Lassa mammarenavirus Species 0.000 claims 2
- 208000009341 RNA Virus Infections Diseases 0.000 claims 2
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 2
- 241000710886 West Nile virus Species 0.000 claims 2
- 241000710772 Yellow fever virus Species 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 229940051021 yellow-fever virus Drugs 0.000 claims 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 208000005176 Hepatitis C Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 230000009089 cytolysis Effects 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 claims 1
- UFEJKYYYVXYMMS-UHFFFAOYSA-N methylcarbamic acid Chemical compound CNC(O)=O UFEJKYYYVXYMMS-UHFFFAOYSA-N 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066277P | 2014-10-20 | 2014-10-20 | |
| US62/066,277 | 2014-10-20 | ||
| US201562104008P | 2015-01-15 | 2015-01-15 | |
| US62/104,008 | 2015-01-15 | ||
| PCT/US2015/056491 WO2016064894A2 (en) | 2014-10-20 | 2015-10-20 | Compositions and methods for detecting an rna virus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020189107A Division JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017536813A JP2017536813A (ja) | 2017-12-14 |
| JP2017536813A5 true JP2017536813A5 (cg-RX-API-DMAC7.html) | 2018-12-06 |
Family
ID=55761744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017521095A Pending JP2017536813A (ja) | 2014-10-20 | 2015-10-20 | Ｒｎａウイルスを検出するための組成物及び方法 |
| JP2020189107A Active JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020189107A Active JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10793922B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP4141128A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2017536813A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107208137A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015336086C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017008082A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2965137A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2017005159A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016064894A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (46)
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| CA2810856C (en) | 2010-08-13 | 2022-05-17 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| JP5801513B2 (ja) | 2012-04-09 | 2015-10-28 | エンバイロロジックス インコーポレイテッド | 試料中の核酸配列を定量するための組成物および方法 |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US20150166982A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting pi3k point mutations |
| JP6596442B2 (ja) | 2014-04-22 | 2019-10-23 | エンバイロロジックス インコーポレイテッド | Ｄｎａ増幅を増強および／または予測するための組成物および方法 |
| EP3177718B1 (en) | 2014-07-30 | 2022-03-16 | President and Fellows of Harvard College | Cas9 proteins including ligand-dependent inteins |
| MX2017005159A (es) | 2014-10-20 | 2017-08-18 | Envirologix Inc | Composiciones y metodos para detectar un virus de rna. |
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| US11832801B2 (en) * | 2016-07-11 | 2023-12-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Sweat as a biofluid for analysis and disease identification |
| JP7231935B2 (ja) | 2016-08-03 | 2023-03-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | アデノシン核酸塩基編集因子およびそれらの使用 |
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| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
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| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
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| EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
| WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
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| CN109593863A (zh) * | 2018-11-28 | 2019-04-09 | 江南大学 | 一种链置换型dna聚合酶诱导等温循环扩增反应检测肉类来源的方法 |
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| JP7602238B2 (ja) | 2019-03-07 | 2024-12-18 | 国立大学法人 長崎大学 | Ｔｅｒｔプロモーター変異を検出するプローブセット |
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| CN111424116B (zh) * | 2020-03-19 | 2023-06-23 | 首都儿科研究所 | 用于检测黄热病毒疫苗株的rt-lamp试剂盒及其专用引物和应用 |
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| DE112021002672T5 (de) | 2020-05-08 | 2023-04-13 | President And Fellows Of Harvard College | Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz |
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| MX2017005159A (es) | 2014-10-20 | 2017-08-18 | Envirologix Inc | Composiciones y metodos para detectar un virus de rna. |
| WO2016069345A1 (en) | 2014-10-28 | 2016-05-06 | Envirologix Inc. | Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis |
| WO2016122698A1 (en) | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
-
2015
- 2015-10-20 MX MX2017005159A patent/MX2017005159A/es unknown
- 2015-10-20 EP EP22187762.4A patent/EP4141128A1/en active Pending
- 2015-10-20 WO PCT/US2015/056491 patent/WO2016064894A2/en not_active Ceased
- 2015-10-20 BR BR112017008082A patent/BR112017008082A2/pt unknown
- 2015-10-20 CN CN201580069867.5A patent/CN107208137A/zh active Pending
- 2015-10-20 JP JP2017521095A patent/JP2017536813A/ja active Pending
- 2015-10-20 AU AU2015336086A patent/AU2015336086C1/en active Active
- 2015-10-20 US US15/520,328 patent/US10793922B2/en active Active
- 2015-10-20 CA CA2965137A patent/CA2965137A1/en active Pending
- 2015-10-20 EP EP15852795.2A patent/EP3209802B1/en not_active Revoked
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2020
- 2020-08-12 US US16/991,216 patent/US12392001B2/en active Active
- 2020-11-13 JP JP2020189107A patent/JP7114676B2/ja active Active
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2021
- 2021-03-03 AU AU2021201378A patent/AU2021201378B2/en active Active
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