JP2017530718A5 - - Google Patents
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- Publication number
- JP2017530718A5 JP2017530718A5 JP2017520418A JP2017520418A JP2017530718A5 JP 2017530718 A5 JP2017530718 A5 JP 2017530718A5 JP 2017520418 A JP2017520418 A JP 2017520418A JP 2017520418 A JP2017520418 A JP 2017520418A JP 2017530718 A5 JP2017530718 A5 JP 2017530718A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- recombinant expression
- expression vector
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013604 expression vector Substances 0.000 claims 10
- 238000003259 recombinant expression Methods 0.000 claims 10
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical group 0.000 claims 7
- 230000001105 regulatory effect Effects 0.000 claims 6
- 102100031181 Glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000699800 Cricetinae Species 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462064335P | 2014-10-15 | 2014-10-15 | |
| US62/064,335 | 2014-10-15 | ||
| PCT/US2015/055549 WO2016061240A1 (en) | 2014-10-15 | 2015-10-14 | Promoter and regulatory elements for improved expression of heterologous genes in host cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530718A JP2017530718A (ja) | 2017-10-19 |
| JP2017530718A5 true JP2017530718A5 (enExample) | 2018-11-22 |
| JP6749898B2 JP6749898B2 (ja) | 2020-09-02 |
Family
ID=54541176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017520418A Active JP6749898B2 (ja) | 2014-10-15 | 2015-10-14 | 宿主細胞における異種由来遺伝子の発現を改善するためのプロモーター及び調節エレメント |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10202616B2 (enExample) |
| EP (2) | EP3207146B1 (enExample) |
| JP (1) | JP6749898B2 (enExample) |
| AU (1) | AU2015332577B2 (enExample) |
| CA (1) | CA2964313C (enExample) |
| ES (2) | ES2900331T3 (enExample) |
| MX (1) | MX377591B (enExample) |
| WO (1) | WO2016061240A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4183412B1 (en) | 2009-07-15 | 2024-08-14 | GlaxoSmithKline Biologicals SA | Rsv f protein compositions and methods for making same |
| RS56748B1 (sr) | 2011-05-13 | 2018-03-30 | Glaxosmithkline Biologicals Sa | Pre-fuzioni rsv f antigeni |
| US20230323287A1 (en) | 2020-10-30 | 2023-10-12 | Amgen Inc. | Overexpression of insulin-like growth factor receptor mutants to modulate igf supplementation |
| CN114196703B (zh) * | 2021-12-22 | 2023-02-03 | 西北农林科技大学 | 一种提高牦牛克隆胚胎发育率的载体、细胞和方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US30985A (en) | 1860-12-18 | Thomas l | ||
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| ATE135045T1 (de) | 1988-07-23 | 1996-03-15 | Delta Biotechnology Ltd | Sekretorische leader-sequenzen |
| WO1990003430A1 (en) | 1988-09-23 | 1990-04-05 | Cetus Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022543D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| EP0626012B1 (en) | 1992-02-11 | 2003-07-09 | Cell Genesys, Inc. | Homogenotization of gene-targeting events |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| ES2301158T3 (es) | 1992-07-24 | 2008-06-16 | Amgen Fremont Inc. | Produccion de anticuerpos xenogenicos. |
| US6054287A (en) | 1994-05-27 | 2000-04-25 | Methodist Hospital Of Indiana, Inc. | Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species |
| US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| GB9712818D0 (en) | 1996-07-08 | 1997-08-20 | Cambridge Antibody Tech | Labelling and selection of specific binding molecules |
| EP1972194A1 (en) | 1996-12-03 | 2008-09-24 | Amgen Fremont Inc. | Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US20030044772A1 (en) | 1997-08-04 | 2003-03-06 | Applied Molecular Evolution [Formerly Ixsys] | Methods for identifying ligand specific binding molecules |
| US6022952A (en) | 1998-04-01 | 2000-02-08 | University Of Alberta | Compositions and methods for protein secretion |
| US20020029391A1 (en) | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
| US6210924B1 (en) | 1998-08-11 | 2001-04-03 | Amgen Inc. | Overexpressing cyclin D 1 in a eukaryotic cell line |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| JP4475814B2 (ja) | 1998-11-20 | 2010-06-09 | 扶桑薬品工業株式会社 | タンパク質発現ベクターとその使用 |
| CA2368068A1 (en) | 1999-03-18 | 2000-09-21 | Steven M. Ruben | 27 human secreted proteins |
| DE60131456T2 (de) | 2000-11-30 | 2008-07-10 | Medarex, Inc., Milpitas | Transchromosomale transgen-nagetiere zur herstellung von humanen antikörpern |
| US20040257396A1 (en) | 2003-06-19 | 2004-12-23 | Toshiba Tec Kabushiki Kaisha | Ink jet head cleaning apparatus and ink jet recording apparatus |
| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| TW200722436A (en) | 2005-10-21 | 2007-06-16 | Hoffmann La Roche | A peptide-immunoglobulin-conjugate |
| WO2008085962A2 (en) * | 2007-01-08 | 2008-07-17 | Millipore Corporation | Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants |
| HK1202578A1 (en) * | 2011-12-07 | 2015-10-02 | Ichnos Sciences SA | Expression cassette |
-
2015
- 2015-10-14 EP EP15794369.7A patent/EP3207146B1/en active Active
- 2015-10-14 MX MX2017004769A patent/MX377591B/es active IP Right Grant
- 2015-10-14 ES ES15794369T patent/ES2900331T3/es active Active
- 2015-10-14 ES ES20173389T patent/ES2962385T3/es active Active
- 2015-10-14 CA CA2964313A patent/CA2964313C/en active Active
- 2015-10-14 AU AU2015332577A patent/AU2015332577B2/en active Active
- 2015-10-14 EP EP20173389.6A patent/EP3722433B1/en active Active
- 2015-10-14 JP JP2017520418A patent/JP6749898B2/ja active Active
- 2015-10-14 US US15/519,820 patent/US10202616B2/en active Active
- 2015-10-14 WO PCT/US2015/055549 patent/WO2016061240A1/en not_active Ceased
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