ES2900331T3 - Elementos promotores y reguladores para mejorar la expresión de genes heterólogos en células hospederas - Google Patents
Elementos promotores y reguladores para mejorar la expresión de genes heterólogos en células hospederas Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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| SI3178490T1 (sl) | 2009-07-15 | 2022-08-31 | Glaxosmithkline Biologicals S.A. | Sestavki proteina F RSV-ja in postopki za pripravo le-teh |
| SI3275892T1 (sl) | 2011-05-13 | 2020-06-30 | Glaxosmithkline Biologicals S.A. | Prefuzijski RSV F antigeni |
| TW202233660A (zh) | 2020-10-30 | 2022-09-01 | 美商安進公司 | 過表現胰島素樣生長因子受體突變體以調節ｉｇｆ補充 |
| CN114196703B (zh) * | 2021-12-22 | 2023-02-03 | 西北农林科技大学 | 一种提高牦牛克隆胚胎发育率的载体、细胞和方法 |
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| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
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| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| DE68925893T2 (de) | 1988-07-23 | 1996-08-08 | Delta Biotechnology Ltd | Sekretorische leader-sequenzen |
| EP0435911B1 (en) | 1988-09-23 | 1996-03-13 | Cetus Oncology Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
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| EP0626012B1 (en) | 1992-02-11 | 2003-07-09 | Cell Genesys, Inc. | Homogenotization of gene-targeting events |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| WO1994002602A1 (en) | 1992-07-24 | 1994-02-03 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
| US6054287A (en) | 1994-05-27 | 2000-04-25 | Methodist Hospital Of Indiana, Inc. | Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species |
| US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| JP4312259B2 (ja) | 1995-04-27 | 2009-08-12 | アムジェン フレモント インク． | 免疫したゼノマウス（ＸｅｎｏＭｏｕｓｅ）に由来するヒト抗体 |
| GB9712818D0 (en) | 1996-07-08 | 1997-08-20 | Cambridge Antibody Tech | Labelling and selection of specific binding molecules |
| DE69738539T2 (de) | 1996-12-03 | 2009-03-26 | Amgen Fremont Inc. | Vollkommen humane Antikörper die EGFR binden |
| WO2000055371A1 (en) | 1999-03-18 | 2000-09-21 | Human Genome Sciences, Inc. | 27 human secreted proteins |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
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| US6022952A (en) | 1998-04-01 | 2000-02-08 | University Of Alberta | Compositions and methods for protein secretion |
| US20020029391A1 (en) | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
| US6210924B1 (en) | 1998-08-11 | 2001-04-03 | Amgen Inc. | Overexpressing cyclin D 1 in a eukaryotic cell line |
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| DK1354034T3 (da) | 2000-11-30 | 2008-03-25 | Medarex Inc | Transgene transchromosomale gnavere til fremstilling af humane antistoffer |
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| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| TW200722436A (en) | 2005-10-21 | 2007-06-16 | Hoffmann La Roche | A peptide-immunoglobulin-conjugate |
| JP2010525789A (ja) * | 2007-01-08 | 2010-07-29 | ミリポア・コーポレイション | １つ又はそれ以上のきょう雑物の低下したレベルの存在下で組換えタンパク質を生産するための細胞培養法 |
| HK1202578A1 (en) * | 2011-12-07 | 2015-10-02 | Ichnos Sciences SA | Expression cassette |
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- 2015-10-14 EP EP15794369.7A patent/EP3207146B1/en active Active
- 2015-10-14 ES ES20173389T patent/ES2962385T3/es active Active
- 2015-10-14 AU AU2015332577A patent/AU2015332577B2/en active Active
- 2015-10-14 CA CA2964313A patent/CA2964313C/en active Active
- 2015-10-14 US US15/519,820 patent/US10202616B2/en active Active
- 2015-10-14 EP EP20173389.6A patent/EP3722433B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3722433A1 (en) | 2020-10-14 |
| EP3207146B1 (en) | 2021-09-29 |
| US10202616B2 (en) | 2019-02-12 |
| US20170253889A1 (en) | 2017-09-07 |
| CA2964313C (en) | 2023-03-14 |
| JP2017530718A (ja) | 2017-10-19 |
| WO2016061240A1 (en) | 2016-04-21 |
| EP3722433B1 (en) | 2023-07-26 |
| EP3207146A1 (en) | 2017-08-23 |
| WO2016061240A8 (en) | 2017-05-18 |
| MX2017004769A (es) | 2017-10-16 |
| CA2964313A1 (en) | 2016-04-21 |
| ES2962385T3 (es) | 2024-03-18 |
| MX377591B (es) | 2025-03-10 |
| AU2015332577B2 (en) | 2021-12-23 |
| JP6749898B2 (ja) | 2020-09-02 |
| AU2015332577A1 (en) | 2017-05-04 |
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