JP2017528485A5 - - Google Patents
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- Publication number
- JP2017528485A5 JP2017528485A5 JP2017514665A JP2017514665A JP2017528485A5 JP 2017528485 A5 JP2017528485 A5 JP 2017528485A5 JP 2017514665 A JP2017514665 A JP 2017514665A JP 2017514665 A JP2017514665 A JP 2017514665A JP 2017528485 A5 JP2017528485 A5 JP 2017528485A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- cycloalkyl
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14185224 | 2014-09-17 | ||
| EP14185224.4 | 2014-09-17 | ||
| PCT/EP2015/070741 WO2016041845A1 (en) | 2014-09-17 | 2015-09-10 | Tetrahydroisoquinoline derivatives and pharmaceutical compositions useful for the treatment of obesity and diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528485A JP2017528485A (ja) | 2017-09-28 |
| JP2017528485A5 true JP2017528485A5 (enExample) | 2018-10-18 |
| JP6559228B2 JP6559228B2 (ja) | 2019-08-14 |
Family
ID=51564524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514665A Expired - Fee Related JP6559228B2 (ja) | 2014-09-17 | 2015-09-10 | 肥満症及び糖尿病の治療に有用なテトラヒドロイソキノリン誘導体及び医薬組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9340510B2 (enExample) |
| EP (1) | EP3194367B1 (enExample) |
| JP (1) | JP6559228B2 (enExample) |
| WO (1) | WO2016041845A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102714554B1 (ko) | 2017-07-11 | 2024-10-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 신규한 치환된 크산틴 유도체 |
| US11459324B2 (en) * | 2018-03-14 | 2022-10-04 | Biogen Ma Inc. | O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors |
| TWI785660B (zh) * | 2020-07-02 | 2022-12-01 | 美商輝瑞大藥廠 | 嘧啶基-3,8-二氮雜雙環[3.2.1]辛烷基甲酮衍生物及其鹽之製備 |
| EP4434520A4 (en) | 2021-11-19 | 2025-10-29 | Shionogi & Co | PHARMACEUTICAL PRODUCT FOR THE TREATMENT OF HEART DISEASE OR SKELETAL MUSCLE DISEASE |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2237850T3 (es) | 1997-10-14 | 2005-08-01 | Mitsubishi Pharma Corporation | Compuestos de piperazina y su uso medicinal. |
| WO2000068202A1 (en) * | 1999-05-06 | 2000-11-16 | Neurogen Corporation | Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands |
| JP2004143134A (ja) * | 2002-02-13 | 2004-05-20 | Takeda Chem Ind Ltd | Ｊｎｋ阻害剤 |
| JP4842963B2 (ja) * | 2004-11-30 | 2011-12-21 | エフ．ホフマン−ラ ロシュ アーゲー | 糖尿病を処置するｄｐｐ−ｉｖ阻害剤としての置換ベンゾキノリジン |
| US7977336B2 (en) | 2006-12-28 | 2011-07-12 | Banyu Pharmaceutical Co. Ltd | Aminopyrimidine derivatives as PLK1 inhibitors |
| CA2724603A1 (en) * | 2008-05-28 | 2009-12-03 | Pfizer Inc. | Pyrazolospiroketone acetyl-coa carboxylase inhibitors |
| WO2010127212A1 (en) * | 2009-04-30 | 2010-11-04 | Forest Laboratories Holdings Limited | Inhibitors of acetyl-coa carboxylase |
| US9006450B2 (en) | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| CN102451178A (zh) | 2010-10-29 | 2012-05-16 | 中国科学院上海药物研究所 | 二氢呋喃-2-酮类化合物在制备抗糖尿病及糖脂代谢药物中的用途 |
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2015
- 2015-09-10 EP EP15760470.3A patent/EP3194367B1/en active Active
- 2015-09-10 WO PCT/EP2015/070741 patent/WO2016041845A1/en not_active Ceased
- 2015-09-10 JP JP2017514665A patent/JP6559228B2/ja not_active Expired - Fee Related
- 2015-09-16 US US14/855,668 patent/US9340510B2/en active Active