JP2017527669A5 - - Google Patents
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- JP2017527669A5 JP2017527669A5 JP2017513127A JP2017513127A JP2017527669A5 JP 2017527669 A5 JP2017527669 A5 JP 2017527669A5 JP 2017513127 A JP2017513127 A JP 2017513127A JP 2017513127 A JP2017513127 A JP 2017513127A JP 2017527669 A5 JP2017527669 A5 JP 2017527669A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- cells
- nucleus
- functional groups
- hydrogel according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920000642 polymer Polymers 0.000 claims 38
- 125000000524 functional group Chemical group 0.000 claims 31
- 239000000017 hydrogel Substances 0.000 claims 24
- 210000004027 cell Anatomy 0.000 claims 11
- 150000003573 thiols Chemical class 0.000 claims 7
- 150000001540 azides Chemical class 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 4
- 150000002019 disulfides Chemical class 0.000 claims 3
- 150000003923 2,5-pyrrolediones Chemical class 0.000 claims 2
- 150000001336 alkenes Chemical class 0.000 claims 2
- 150000001345 alkine derivatives Chemical class 0.000 claims 2
- 210000002919 epithelial cell Anatomy 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 210000001789 adipocyte Anatomy 0.000 claims 1
- 210000002453 autonomic neuron Anatomy 0.000 claims 1
- 210000004082 barrier epithelial cell Anatomy 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 210000000601 blood cell Anatomy 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
- 210000002257 embryonic structure Anatomy 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 230000003394 haemopoietic effect Effects 0.000 claims 1
- 210000002064 heart cell Anatomy 0.000 claims 1
- 210000003494 hepatocyte Anatomy 0.000 claims 1
- 210000003630 histaminocyte Anatomy 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 210000000987 immune system Anatomy 0.000 claims 1
- 210000003292 kidney cell Anatomy 0.000 claims 1
- 210000003644 lens cell Anatomy 0.000 claims 1
- 125000003473 lipid group Chemical group 0.000 claims 1
- 210000001616 monocyte Anatomy 0.000 claims 1
- 210000004498 neuroglial cell Anatomy 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 210000000440 neutrophil Anatomy 0.000 claims 1
- 230000000474 nursing effect Effects 0.000 claims 1
- 210000000578 peripheral nerve Anatomy 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 210000000697 sensory organ Anatomy 0.000 claims 1
- 230000009209 sensory transmission Effects 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 210000002536 stromal cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462048155P | 2014-09-09 | 2014-09-09 | |
| US62/048,155 | 2014-09-09 | ||
| PCT/US2015/049197 WO2016040489A1 (en) | 2014-09-09 | 2015-09-09 | Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methds for their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020090650A Division JP2020139163A (ja) | 2014-09-09 | 2020-05-25 | 官能性双性イオン性ポリマーおよび混合電荷ポリマー、関連するヒドロゲルならびにこれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527669A JP2017527669A (ja) | 2017-09-21 |
| JP2017527669A5 true JP2017527669A5 (https=) | 2018-10-11 |
| JP6709780B2 JP6709780B2 (ja) | 2020-06-17 |
Family
ID=55459518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017513127A Active JP6709780B2 (ja) | 2014-09-09 | 2015-09-09 | 官能性双性イオン性ポリマーおよび混合電荷ポリマー、関連するヒドロゲルならびにこれらの使用方法 |
| JP2020090650A Pending JP2020139163A (ja) | 2014-09-09 | 2020-05-25 | 官能性双性イオン性ポリマーおよび混合電荷ポリマー、関連するヒドロゲルならびにこれらの使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020090650A Pending JP2020139163A (ja) | 2014-09-09 | 2020-05-25 | 官能性双性イオン性ポリマーおよび混合電荷ポリマー、関連するヒドロゲルならびにこれらの使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10272180B2 (https=) |
| EP (1) | EP3191016B1 (https=) |
| JP (2) | JP6709780B2 (https=) |
| CN (1) | CN106999270B (https=) |
| WO (1) | WO2016040489A1 (https=) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| CN103347562B (zh) | 2010-12-08 | 2016-08-10 | 康沃特克科技公司 | 伤口分泌液系统附件 |
| JP5965409B2 (ja) | 2010-12-08 | 2016-08-03 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 創傷滲出液を評価するための統合システム |
| PL2648795T3 (pl) | 2010-12-08 | 2023-05-08 | Convatec Technologies Inc. | System do usuwania wysięków z miejsca rany |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| ES2690824T3 (es) | 2012-07-02 | 2018-11-22 | Boston Scientific Scimed, Inc. | Formación de prótesis valvular cardiaca |
| JP2016507663A (ja) | 2012-12-20 | 2016-03-10 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 化学修飾セルロース系繊維の加工 |
| EP3191016B1 (en) | 2014-09-09 | 2021-10-27 | University of Washington | Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use |
| US10426609B2 (en) | 2015-04-09 | 2019-10-01 | Boston Scientific Scimed, Inc. | Fiber reinforced prosthetic heart valve having undulating fibers |
| US10299915B2 (en) * | 2015-04-09 | 2019-05-28 | Boston Scientific Scimed, Inc. | Synthetic heart valves composed of zwitterionic polymers |
| US10314696B2 (en) | 2015-04-09 | 2019-06-11 | Boston Scientific Scimed, Inc. | Prosthetic heart valves having fiber reinforced leaflets |
| US10716671B2 (en) | 2015-07-02 | 2020-07-21 | Boston Scientific Scimed, Inc. | Prosthetic heart valve composed of composite fibers |
| US10413403B2 (en) | 2015-07-14 | 2019-09-17 | Boston Scientific Scimed, Inc. | Prosthetic heart valve including self-reinforced composite leaflets |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| WO2017173069A1 (en) | 2016-03-30 | 2017-10-05 | Convatec Technologies Inc. | Detecting microbial infections in wounds |
| WO2017212345A2 (en) | 2016-03-30 | 2017-12-14 | Synovo Gmbh | Detecting microbial infection in wounds |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| US10368982B2 (en) | 2016-05-19 | 2019-08-06 | Boston Scientific Scimed, Inc. | Prosthetic valves, valve leaflets and related methods |
| JP7071957B2 (ja) | 2016-07-08 | 2022-05-19 | コンバテック・テクノロジーズ・インコーポレイテッド | 可撓性陰圧システム |
| BR112019000284A2 (pt) | 2016-07-08 | 2019-04-16 | Convatec Technologies Inc. | aparelho de coleta de fluido |
| ES2912094T3 (es) | 2016-07-08 | 2022-05-24 | Convatec Technologies Inc | Detección de flujo de fluidos |
| CN109843332A (zh) * | 2016-07-22 | 2019-06-04 | 华盛顿大学 | 两性离子微凝胶、其组件和相关制剂及其使用方法 |
| US10995361B2 (en) | 2017-01-23 | 2021-05-04 | Massachusetts Institute Of Technology | Multiplexed signal amplified FISH via splinted ligation amplification and sequencing |
| CA3050264A1 (en) * | 2017-01-24 | 2018-08-02 | Fred Hutchinson Cancer Research Center | Systems and methods for hematopoietic cell expansion utilizing hydrogels |
| KR102228571B1 (ko) * | 2017-02-09 | 2021-03-16 | 주식회사 메디폴리머 | 정신질환 또는 중추신경계 질환 치료용 약물전달 제형 |
| WO2018157074A1 (en) | 2017-02-24 | 2018-08-30 | Massachusetts Institute Of Technology | Methods for diagnosing neoplastic lesions |
| WO2018157048A1 (en) | 2017-02-24 | 2018-08-30 | Massachusetts Institute Of Technology | Methods for examining podocyte foot processes in human renal samples using conventional optical microscopy |
| CN110494170A (zh) | 2017-04-25 | 2019-11-22 | 波士顿科学国际有限公司 | 生物相容性聚异丁烯-纤维复合材料和方法 |
| JP7208169B2 (ja) * | 2017-05-30 | 2023-01-18 | マクマスター ユニバーシティー | 新規合成ポリマーおよび架橋ヒドロゲルシステム |
| EP3658659A1 (en) * | 2017-07-24 | 2020-06-03 | Union Carbide Chemicals & Plastics Technology LLC | Detergent formulation containing mixed-charge polymers |
| WO2019022867A1 (en) * | 2017-07-24 | 2019-01-31 | Union Carbide Chemicals & Plastics Technology Llc | MIXED LOAD POLYMERS |
| WO2019022866A1 (en) * | 2017-07-24 | 2019-01-31 | Union Carbide Chemicals & Plastics Technology Llc | COUNTER-IONS MONOMERS AND POLYMERS WITH MIXED LOAD PRODUCTS THEREFROM |
| AU2018306909A1 (en) * | 2017-07-24 | 2020-02-20 | Rohm And Haas Company | Chloride-free cationic polymers using acetate anions |
| AU2018306910A1 (en) * | 2017-07-24 | 2020-02-20 | Rohm And Haas Company | Chloride-free cationic polymers using acetate anions |
| US12161792B2 (en) | 2017-11-16 | 2024-12-10 | Convatec Limited | Fluid collection apparatus |
| JP7129668B2 (ja) * | 2018-01-18 | 2022-09-02 | 国立大学法人東海国立大学機構 | 容器及びその使用 |
| US11873374B2 (en) | 2018-02-06 | 2024-01-16 | Massachusetts Institute Of Technology | Swellable and structurally homogenous hydrogels and methods of use thereof |
| JP7359998B2 (ja) * | 2018-05-11 | 2023-10-12 | 国立大学法人 東京大学 | 双性イオン基含有ポリマーハイドロゲル |
| WO2020013833A1 (en) | 2018-07-13 | 2020-01-16 | Massachusetts Institute Of Technology | Dimethylacrylamide (dmaa) hydrogel for expansion microscopy (exm) |
| WO2020106338A2 (en) | 2018-08-14 | 2020-05-28 | University Of Washington | Zwitterionic double network hydrogels |
| KR102040083B1 (ko) * | 2018-09-06 | 2019-11-05 | 숭실대학교산학협력단 | 초분자 구조체 및 그 제조 방법과 자가치유 탄성체 |
| EP3863610A4 (en) * | 2018-10-10 | 2023-03-29 | University of Washington | High-polymer-density bioconjugate compositions and related methods |
| CN113454166A (zh) * | 2018-12-19 | 2021-09-28 | 泰普鲁特医疗技术有限责任公司 | 基于多糖和两性离子聚合物的水凝胶组合物及其使用方法 |
| US12405193B2 (en) | 2019-02-22 | 2025-09-02 | Massachusetts Institute Of Technology | Iterative direct expansion microscopy |
| US12559867B2 (en) | 2019-04-30 | 2026-02-24 | Cornell University | Fibers of polymers that have a backbone including a positively charged component of a zwitterionic moiety, and their use in implantable therapeutic delivery systems |
| EP4295869B1 (en) | 2019-06-03 | 2026-01-28 | Convatec Limited | Devices to disrupt and contain pathogens |
| CN112587667A (zh) * | 2019-09-16 | 2021-04-02 | 天津大学 | 一种长循环的cbma构建的纳米载体及其制备方法 |
| WO2021072281A1 (en) * | 2019-10-11 | 2021-04-15 | University Of Washington | Modified endonucleases and related methods |
| CN110698576A (zh) * | 2019-10-22 | 2020-01-17 | 南京师范大学 | 一种两性离子聚合物作为大分子pH缓冲材料的应用 |
| US12265004B2 (en) | 2019-11-05 | 2025-04-01 | Massachusetts Institute Of Technology | Membrane probes for expansion microscopy |
| US12245935B2 (en) | 2019-11-26 | 2025-03-11 | Boston Scientific Limited | Composite web-polymer heart valve |
| WO2021113505A1 (en) | 2019-12-05 | 2021-06-10 | Massachusetts Institute Of Technology | Method for preparing a specimen for expansion microscopy |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| JP2023527796A (ja) * | 2020-05-28 | 2023-06-30 | マックマスター、ユニバーシティー | インサイチュゲル化両性イオン性ヒドロゲル組成物、及びその使用方法 |
| WO2022071417A1 (ja) | 2020-09-29 | 2022-04-07 | キッコーマン株式会社 | フラビン依存性乳酸デヒドロゲナーゼを含む組成物の安定性を向上する方法 |
| CN112225829B (zh) * | 2020-10-29 | 2021-08-24 | 江南大学 | 一种末端带电荷多糖及其制备方法 |
| CN112760023B (zh) * | 2021-01-25 | 2022-04-26 | 四川大学 | 一种混合电荷聚氨酯涂层材料及其制备方法与应用 |
| CN113101412A (zh) * | 2021-03-02 | 2021-07-13 | 四川大学华西医院 | 一种长效稳定的抗凝生物瓣膜材料及其制备方法 |
| US20240181404A1 (en) * | 2021-04-22 | 2024-06-06 | Trustees Of Tufts College | Cross-linked zwitterionic polymer network and their use in membrane filters |
| CN113476661B (zh) * | 2021-07-05 | 2022-08-05 | 中国医学科学院生物医学工程研究所 | 一种三层结构复合型自愈合人造血管及其制备方法 |
| WO2024138098A1 (en) * | 2022-12-22 | 2024-06-27 | Trustees Of Tufts College | Method for making cross-linkable zwitterionic polymer membranes and their use |
| WO2024249557A2 (en) * | 2023-05-30 | 2024-12-05 | Cornell University | Zwitterionic hydrogels for the culture, expansion, and protection of cells and cell-derived products |
| WO2024254586A1 (en) * | 2023-06-09 | 2024-12-12 | Trustees Of Tufts College | Zwitterion-containing additive for surface functionalization of silicone materials |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06509889A (ja) * | 1992-06-19 | 1994-11-02 | エフ・ホフマン−ラ ロシュ アーゲー | 光学的非線形ポリマー |
| JP3785599B2 (ja) * | 1995-02-03 | 2006-06-14 | ノバルティス アクチエンゲゼルシャフト | エステル又はアミド基を含む架橋ポリマー |
| US6150472A (en) * | 1995-12-22 | 2000-11-21 | Holland Biomaterials Group B.V. | Multi-functional site containing polymers, and applications thereof |
| US6156478A (en) * | 1998-10-30 | 2000-12-05 | 3M Innovative Properties Company | Photocurable and photopatternable hydrogel matrix based on azlactone copolymers |
| US20030100830A1 (en) * | 2001-11-27 | 2003-05-29 | Sheng-Ping Zhong | Implantable or insertable medical devices visible under magnetic resonance imaging |
| CA2487030A1 (en) * | 2002-06-11 | 2003-12-18 | Basf Aktiengesellschaft | (meth)acrylic esters of polyalkoxylated glycerine |
| DE10358372A1 (de) | 2003-04-03 | 2004-10-14 | Basf Ag | Gemische von Verbindungen mit mindestens zwei Doppelbindungen und deren Verwendung |
| US20110097277A1 (en) * | 2005-08-25 | 2011-04-28 | University Of Washington | Particles coated with zwitterionic polymers |
| JP6085075B2 (ja) * | 2005-08-25 | 2017-02-22 | ユニヴァーシティ オブ ワシントン | 超低汚損スルホベタインおよびカルボキシベタイン材料ならびに関連する方法 |
| JP2009532383A (ja) * | 2006-03-30 | 2009-09-10 | ジェレシス， インク． | 胃充填材としてのポリマ材料及びそれらの調製 |
| US7910135B2 (en) * | 2006-10-13 | 2011-03-22 | Uluru Inc. | Hydrogel wound dressing and biomaterials formed in situ and their uses |
| EP2099845B1 (en) * | 2006-11-27 | 2020-12-23 | Actamax Surgical Materials LLC | Multi-functional polyalkylene oxides, hydrogels and tissue adhesives |
| MX2009007101A (es) * | 2006-12-29 | 2009-12-01 | Univ Washington | Superficies y materiales antibioincrustación bifuncionales. |
| US8067028B2 (en) | 2007-08-13 | 2011-11-29 | Confluent Surgical Inc. | Drug delivery device |
| WO2009067565A2 (en) | 2007-11-19 | 2009-05-28 | University Of Washington | Marine coatings |
| US8658192B2 (en) * | 2007-11-19 | 2014-02-25 | University Of Washington | Integrated antimicrobial and low fouling materials |
| WO2009067566A1 (en) * | 2007-11-19 | 2009-05-28 | University Of Washington | Hemostatic wound dressings |
| EP2352522A4 (en) | 2008-11-06 | 2014-03-05 | Univ Washington | BISPECIFIC AUXILIARIES FOR INTRA-CELLULAR RELEASE |
| NZ593201A (en) * | 2008-12-05 | 2013-05-31 | Semprus Biosciences Corp | Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions |
| CN102317332B (zh) | 2008-12-12 | 2014-04-30 | 马萨诸塞大学 | 两性离子聚合物 |
| US8497356B2 (en) | 2009-02-17 | 2013-07-30 | Duke University | Biomolecule polymer conjugates and methods for making the same |
| CN102905730A (zh) | 2009-11-06 | 2013-01-30 | 华盛顿大学商业中心 | 两性离子聚合物生物缀合物以及相关的方法 |
| WO2011057219A2 (en) | 2009-11-06 | 2011-05-12 | University Of Washington Through Its Center For Commercialization | Crosslinked zwitterionic hydrogels |
| CA2799786A1 (en) | 2010-06-09 | 2011-12-15 | Semprus Biosciences Corp. | Non-fouling, anti-microbial, anti-thrombogenic graft compositions |
| EP2670757B1 (en) | 2011-02-01 | 2015-05-27 | DSM IP Assets B.V. | Silicone containing monomers with hydrophilic end groups |
| EP3191016B1 (en) | 2014-09-09 | 2021-10-27 | University of Washington | Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use |
-
2015
- 2015-09-09 EP EP15840077.0A patent/EP3191016B1/en active Active
- 2015-09-09 US US15/509,607 patent/US10272180B2/en active Active
- 2015-09-09 CN CN201580058874.5A patent/CN106999270B/zh active Active
- 2015-09-09 JP JP2017513127A patent/JP6709780B2/ja active Active
- 2015-09-09 WO PCT/US2015/049197 patent/WO2016040489A1/en not_active Ceased
-
2019
- 2019-04-29 US US16/398,002 patent/US10828398B2/en active Active
-
2020
- 2020-05-25 JP JP2020090650A patent/JP2020139163A/ja active Pending
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