JP2017527313A5 - - Google Patents
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- JP2017527313A5 JP2017527313A5 JP2017533733A JP2017533733A JP2017527313A5 JP 2017527313 A5 JP2017527313 A5 JP 2017527313A5 JP 2017533733 A JP2017533733 A JP 2017533733A JP 2017533733 A JP2017533733 A JP 2017533733A JP 2017527313 A5 JP2017527313 A5 JP 2017527313A5
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- polynucleotide
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- 108091033319 polynucleotide Proteins 0.000 claims description 570
- 102000040430 polynucleotide Human genes 0.000 claims description 570
- 239000002157 polynucleotide Substances 0.000 claims description 569
- 238000000034 method Methods 0.000 claims description 444
- 230000000295 complement effect Effects 0.000 claims description 259
- 210000004027 cell Anatomy 0.000 claims description 170
- 239000000203 mixture Substances 0.000 claims description 147
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- 238000003199 nucleic acid amplification method Methods 0.000 claims description 40
- 108060003951 Immunoglobulin Proteins 0.000 claims description 38
- 102000018358 immunoglobulin Human genes 0.000 claims description 38
- 102000039446 nucleic acids Human genes 0.000 claims description 27
- 108020004707 nucleic acids Proteins 0.000 claims description 27
- 150000007523 nucleic acids Chemical class 0.000 claims description 27
- 102100034343 Integrase Human genes 0.000 claims description 24
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims description 24
- 238000012163 sequencing technique Methods 0.000 claims description 15
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- 108010008286 DNA nucleotidylexotransferase Proteins 0.000 claims description 11
- 210000004602 germ cell Anatomy 0.000 claims description 11
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- 108020004635 Complementary DNA Proteins 0.000 claims 1
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- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical group CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 description 16
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- 229940113082 thymine Drugs 0.000 description 8
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- 241000713838 Avian myeloblastosis virus Species 0.000 description 4
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- 230000002934 lysing effect Effects 0.000 description 3
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- 201000009030 Carcinoma Diseases 0.000 description 2
- 208000005243 Chondrosarcoma Diseases 0.000 description 2
- 108091026890 Coding region Proteins 0.000 description 2
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- 206010018338 Glioma Diseases 0.000 description 2
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- 241001465754 Metazoa Species 0.000 description 2
- 241000713869 Moloney murine leukemia virus Species 0.000 description 2
- 206010039491 Sarcoma Diseases 0.000 description 2
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- 230000037430 deletion Effects 0.000 description 2
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- 208000032839 leukemia Diseases 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 210000001806 memory b lymphocyte Anatomy 0.000 description 2
- 108020004999 messenger RNA Proteins 0.000 description 2
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- 230000003472 neutralizing effect Effects 0.000 description 2
- 201000008968 osteosarcoma Diseases 0.000 description 2
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- 206010069754 Acquired gene mutation Diseases 0.000 description 1
- 108700028369 Alleles Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
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- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 description 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 description 1
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020036503A JP6960490B2 (ja) | 2014-09-15 | 2020-03-04 | ハイスループットヌクレオチドライブラリーシークエンシング |
| JP2021166730A JP7278352B2 (ja) | 2014-09-15 | 2021-10-11 | ハイスループットヌクレオチドライブラリーシークエンシング |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050549P | 2014-09-15 | 2014-09-15 | |
| US62/050,549 | 2014-09-15 | ||
| US201462051832P | 2014-09-17 | 2014-09-17 | |
| US62/051,832 | 2014-09-17 | ||
| PCT/US2015/050119 WO2016044227A1 (en) | 2014-09-15 | 2015-09-15 | High-throughput nucleotide library sequencing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036503A Division JP6960490B2 (ja) | 2014-09-15 | 2020-03-04 | ハイスループットヌクレオチドライブラリーシークエンシング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527313A JP2017527313A (ja) | 2017-09-21 |
| JP2017527313A5 true JP2017527313A5 (enExample) | 2018-11-01 |
| JP6672310B2 JP6672310B2 (ja) | 2020-03-25 |
Family
ID=54291588
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533733A Active JP6672310B2 (ja) | 2014-09-15 | 2015-09-15 | ハイスループットヌクレオチドライブラリーシークエンシング |
| JP2020036503A Active JP6960490B2 (ja) | 2014-09-15 | 2020-03-04 | ハイスループットヌクレオチドライブラリーシークエンシング |
| JP2021166730A Active JP7278352B2 (ja) | 2014-09-15 | 2021-10-11 | ハイスループットヌクレオチドライブラリーシークエンシング |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036503A Active JP6960490B2 (ja) | 2014-09-15 | 2020-03-04 | ハイスループットヌクレオチドライブラリーシークエンシング |
| JP2021166730A Active JP7278352B2 (ja) | 2014-09-15 | 2021-10-11 | ハイスループットヌクレオチドライブラリーシークエンシング |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10590483B2 (enExample) |
| EP (3) | EP3950944A1 (enExample) |
| JP (3) | JP6672310B2 (enExample) |
| KR (1) | KR102541849B1 (enExample) |
| CN (1) | CN107002076B (enExample) |
| AU (2) | AU2015318011B2 (enExample) |
| CA (1) | CA2961210A1 (enExample) |
| ES (2) | ES2727656T3 (enExample) |
| IL (1) | IL251123B (enExample) |
| MX (1) | MX378730B (enExample) |
| NZ (2) | NZ767927A (enExample) |
| SG (2) | SG10201911069WA (enExample) |
| WO (1) | WO2016044227A1 (enExample) |
| ZA (1) | ZA201701916B (enExample) |
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| DK2414547T3 (da) | 2009-04-02 | 2014-06-16 | Fluidigm Corp | Multiprimer-amplifikationsmetode til stregkodning af målnukleinsyrer |
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| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
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