DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
US6943034B1
(en)
|
1991-11-22 |
2005-09-13 |
Affymetrix, Inc. |
Combinatorial strategies for polymer synthesis
|
EP0617706B1
(en)
|
1991-11-25 |
2001-10-17 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
CA2704228C
(en)
|
1995-03-10 |
2013-10-22 |
Meso Scale Technologies, Llc |
Multi-array, multi-specific electrochemiluminescence testing
|
US6632436B2
(en)
|
1996-01-25 |
2003-10-14 |
Genitrix Llc |
Vaccine compositions and method of modulating immune responses
|
US6165739A
(en)
|
1996-03-13 |
2000-12-26 |
Compucyte Corporation |
Multiple simultaneous testing media
|
US6039897A
(en)
|
1996-08-28 |
2000-03-21 |
University Of Washington |
Multiple patterned structures on a single substrate fabricated by elastomeric micro-molding techniques
|
US6924153B1
(en)
|
1997-03-06 |
2005-08-02 |
Quidel Corporation |
Quantitative lateral flow assays and devices
|
US5858801A
(en)
|
1997-03-13 |
1999-01-12 |
The United States Of America As Represented By The Secretary Of The Navy |
Patterning antibodies on a surface
|
AU730827B2
(en)
|
1997-06-09 |
2001-03-15 |
Caliper Technologies Corporation |
Apparatus and methods for correcting for variable velocity in microfluidic systems
|
US20030096232A1
(en)
|
1997-12-19 |
2003-05-22 |
Kris Richard M. |
High throughput assay system
|
US6210910B1
(en)
|
1998-03-02 |
2001-04-03 |
Trustees Of Tufts College |
Optical fiber biosensor array comprising cell populations confined to microcavities
|
US6316193B1
(en)
|
1998-10-06 |
2001-11-13 |
Origene Technologies, Inc. |
Rapid-screen cDNA library panels
|
US6429027B1
(en)
|
1998-12-28 |
2002-08-06 |
Illumina, Inc. |
Composite arrays utilizing microspheres
|
US6613513B1
(en)
|
1999-02-23 |
2003-09-02 |
Caliper Technologies Corp. |
Sequencing by incorporation
|
US8008071B2
(en)
|
1999-11-08 |
2011-08-30 |
University Of South Florida |
Compositions and methods for detecting intracellular glucose and analogs thereof
|
US6875619B2
(en)
|
1999-11-12 |
2005-04-05 |
Motorola, Inc. |
Microfluidic devices comprising biochannels
|
US20020090649A1
(en)
|
1999-12-15 |
2002-07-11 |
Tony Chan |
High density column and row addressable electrode arrays
|
US6699665B1
(en)
|
2000-11-08 |
2004-03-02 |
Surface Logix, Inc. |
Multiple array system for integrating bioarrays
|
WO2002044695A1
(en)
|
2000-11-16 |
2002-06-06 |
Burstein Technologies, Inc. |
Methods and apparatus for detecting and quantifying lymphocytes with optical biodiscs
|
US20020100714A1
(en)
|
2001-01-31 |
2002-08-01 |
Sau Lan Tang Staats |
Microfluidic devices
|
EP1372828A4
(en)
|
2001-03-24 |
2008-10-29 |
Aviva Biosciences Corp |
BIOCHIPS WITH ION TRANSPORTATION STRUCTURES AND USE METHOD
|
WO2002080647A2
(en)
|
2001-04-03 |
2002-10-17 |
Surromed, Inc. |
Methods and reagents for multiplexed analyte capture, surface array self-assembly, and analysis of complex biological samples
|
DE10127221A1
(de)
|
2001-05-23 |
2002-11-28 |
Lifebits Ag |
Träger für chemische, biochemische und biologische Substanzen
|
US7473767B2
(en)
|
2001-07-03 |
2009-01-06 |
The Institute For Systems Biology |
Methods for detection and quantification of analytes in complex mixtures
|
US7023007B2
(en)
|
2001-07-17 |
2006-04-04 |
Caliper Life Sciences, Inc. |
Methods and systems for alignment of detection optics
|
US10539561B1
(en)
|
2001-08-30 |
2020-01-21 |
Customarray, Inc. |
Enzyme-amplified redox microarray detection process
|
US7381375B2
(en)
|
2001-10-26 |
2008-06-03 |
Millipore Corporation |
Assay systems with adjustable fluid communication
|
US20050032144A1
(en)
|
2001-11-16 |
2005-02-10 |
Lombardi Vincent C |
Method for selective conjugation of analytes to enzymes without unwanted enzyme-enzyme cross-linking
|
US7057026B2
(en)
|
2001-12-04 |
2006-06-06 |
Solexa Limited |
Labelled nucleotides
|
CA2468674A1
(en)
|
2001-12-05 |
2003-06-12 |
University Of Washington |
Microfluidic device and surface decoration process for solid phase affinity binding assays
|
US20030190689A1
(en)
|
2002-04-05 |
2003-10-09 |
Cell Signaling Technology,Inc. |
Molecular profiling of disease and therapeutic response using phospho-specific antibodies
|
SI3587433T1
(sl)
|
2002-08-23 |
2020-08-31 |
Illumina Cambridge Limited |
Modificirani nukleotidi
|
AU2002952384A0
(en)
|
2002-10-31 |
2002-11-14 |
Swinburne University Of Technology |
Structures
|
DE10305050A1
(de)
|
2003-02-07 |
2004-08-19 |
Roche Diagnostics Gmbh |
Analytisches Testelement und Verfahren für Blutuntersuchungen
|
US7312197B2
(en)
|
2003-02-24 |
2007-12-25 |
University Of Maryland, Baltimore |
Method of modifying glucose activity using polypeptides selectively expressed in fat tissue
|
US7452678B2
(en)
|
2003-06-24 |
2008-11-18 |
Bristol-Myers Squibb Company |
Identification of biomarkers for liver toxicity
|
US20060263783A1
(en)
|
2003-07-03 |
2006-11-23 |
Podhajcer Osvaldo L |
Methods and systems for diagnosis of non-central nervous system (cns) diseases in cns samples
|
US20050226779A1
(en)
|
2003-09-19 |
2005-10-13 |
Oldham Mark F |
Vacuum assist for a microplate
|
US7981362B2
(en)
|
2003-11-04 |
2011-07-19 |
Meso Scale Technologies, Llc |
Modular assay plates, reader systems and methods for test measurements
|
US7169560B2
(en)
|
2003-11-12 |
2007-01-30 |
Helicos Biosciences Corporation |
Short cycle methods for sequencing polynucleotides
|
EP1682261B1
(en)
|
2003-11-12 |
2012-08-15 |
BIO-RAD Haifa Ltd. |
Method for carrying out multiple binding reactions in an array format
|
AU2005216095B2
(en)
|
2004-02-20 |
2009-09-17 |
The Regents Of The University Of California |
Salivary mRNA profiling, biomarkers, and related methods and kits of parts
|
US20080254997A1
(en)
|
2004-03-18 |
2008-10-16 |
Nissui Pharmaceutical Co., Ltd. |
Kit, Device and Method For Analyzing Biological Substance
|
DE102004056735A1
(de)
|
2004-11-09 |
2006-07-20 |
Clondiag Chip Technologies Gmbh |
Vorrichtung für die Durchführung und Analyse von Mikroarray-Experimenten
|
CN1296492C
(zh)
|
2004-11-18 |
2007-01-24 |
博奥生物有限公司 |
一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
|
US20060246475A1
(en)
|
2005-01-21 |
2006-11-02 |
Third Wave Technologies |
Compositions and methods for increased dynamic range detection of nucleic acids
|
GB0508983D0
(en)
|
2005-05-03 |
2005-06-08 |
Oxford Gene Tech Ip Ltd |
Cell analyser
|
EP1888790A2
(en)
|
2005-05-06 |
2008-02-20 |
The Regents of the University of California |
Microfluidic system for identifying or sizing individual particles passing through a channel
|
US20060263818A1
(en)
|
2005-05-23 |
2006-11-23 |
Axel Scherer |
High throughput multi-antigen microfluidic fluorescence immunoassays
|
GB0514935D0
(en)
|
2005-07-20 |
2005-08-24 |
Solexa Ltd |
Methods for sequencing a polynucleotide template
|
WO2007014267A2
(en)
|
2005-07-26 |
2007-02-01 |
Oregon Health & Science University |
Nanoparticle probes for capture, sorting and placement of targets
|
US20100297145A1
(en)
|
2005-08-04 |
2010-11-25 |
Kazutake Tsujikawa |
Apoptosis promoter, cell proliferation inhibitor, prophylactic/therapeutic agent for cancer, screening method for the promoter, inhibitor or agent
|
US7666593B2
(en)
|
2005-08-26 |
2010-02-23 |
Helicos Biosciences Corporation |
Single molecule sequencing of captured nucleic acids
|
WO2007033385A2
(en)
|
2005-09-13 |
2007-03-22 |
Fluidigm Corporation |
Microfluidic assay devices and methods
|
US7776553B2
(en)
|
2005-09-16 |
2010-08-17 |
Presidents And Fellows Of Harvard College |
Screening assays and methods
|
US20070122819A1
(en)
|
2005-11-25 |
2007-05-31 |
Industrial Technology Research Institute |
Analyte assay structure in microfluidic chip for quantitative analysis and method for using the same
|
AU2006330913B2
(en)
|
2005-12-21 |
2011-10-27 |
Meso Scale Technologies, Llc |
Assay modules having assay reagents and methods of making and using same
|
AU2007212306A1
(en)
|
2006-02-07 |
2007-08-16 |
Wafergen, Inc. |
Temperature-regulated culture plates
|
US8460879B2
(en)
|
2006-02-21 |
2013-06-11 |
The Trustees Of Tufts College |
Methods and arrays for target analyte detection and determination of target analyte concentration in solution
|
US7282337B1
(en)
|
2006-04-14 |
2007-10-16 |
Helicos Biosciences Corporation |
Methods for increasing accuracy of nucleic acid sequencing
|
WO2008016680A1
(en)
|
2006-08-02 |
2008-02-07 |
California Institute Of Technology |
Methods and systems for detecting and/or sorting targets
|
US8394590B2
(en)
|
2006-08-02 |
2013-03-12 |
California Institute Of Technology |
Capture agents and related methods and systems for detecting and/or sorting targets
|
US8399188B2
(en)
|
2006-09-28 |
2013-03-19 |
Illumina, Inc. |
Compositions and methods for nucleotide sequencing
|
US7863035B2
(en)
|
2007-02-15 |
2011-01-04 |
Osmetech Technology Inc. |
Fluidics devices
|
JP2009002806A
(ja)
|
2007-06-21 |
2009-01-08 |
Hitachi Ltd |
化学発光計測装置
|
EP2167633A4
(en)
|
2007-07-16 |
2014-12-24 |
California Inst Of Techn |
MICROFLUIDIC DEVICES, METHODS AND SYSTEMS FOR DETECTING TARGET MOLECULES
|
WO2009105583A1
(en)
|
2008-02-19 |
2009-08-27 |
Anstron Technologies Company |
Fluorescence resonance energy transfer (fret) binding assays that are surface-based
|
US8871527B2
(en)
|
2008-04-29 |
2014-10-28 |
Becton, Dickinson And Company |
Method and system for measuring a sample to determine the presence of and optionally treat a pathologic condition
|
DK2297333T3
(da)
|
2008-05-30 |
2015-04-07 |
Massachusetts Inst Technology |
Fremgangsmåde til rumlig adskillelse og til screening af celler
|
CN102177434B
(zh)
|
2008-08-08 |
2014-04-02 |
乔治亚大学研究基金公司 |
用于预测能够分泌至体液中的蛋白质的方法及系统
|
WO2010027003A1
(ja)
|
2008-09-02 |
2010-03-11 |
独立行政法人産業技術総合研究所 |
細胞検出方法及び該方法に用いるマイクロアレイチップ
|
JP2010066146A
(ja)
|
2008-09-11 |
2010-03-25 |
Panasonic Corp |
マイクロアレイ測定方法
|
AU2009322105B2
(en)
|
2008-12-04 |
2015-07-02 |
Massachusetts Institute Of Technology |
Method for diagnosing allergic reactions
|
EP2607496B1
(en)
|
2008-12-23 |
2014-07-16 |
Illumina, Inc. |
Methods useful in nucleic acid sequencing protocols
|
EP2393596B1
(en)
|
2009-02-09 |
2016-09-28 |
Whitespace Enterprise Corporation |
Microfluidic devices and methods of providing a storable sample
|
US8317737B2
(en)
|
2009-02-25 |
2012-11-27 |
The Invention Science Fund I, Llc |
Device for actively removing a target component from blood or lymph of a vertebrate subject
|
ES2555389T3
(es)
|
2009-03-30 |
2015-12-30 |
Illumina, Inc. |
Análisis de expresión génica en células individuales
|
WO2010127304A2
(en)
|
2009-05-01 |
2010-11-04 |
Illumina, Inc. |
Sequencing methods
|
GB0909923D0
(en)
|
2009-06-09 |
2009-07-22 |
Oxford Gene Tech Ip Ltd |
Picowell capture devices for analysing single cells or other particles
|
EP2467479B1
(en)
|
2009-08-20 |
2016-01-06 |
Population Genetics Technologies Ltd |
Compositions and methods for intramolecular nucleic acid rearrangement
|
EP2473857B1
(en)
|
2009-09-01 |
2021-09-29 |
Corsolutions, LLC |
Microfluidic interface
|
US9500645B2
(en)
|
2009-11-23 |
2016-11-22 |
Cyvek, Inc. |
Micro-tube particles for microfluidic assays and methods of manufacture
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
CA2794522C
(en)
|
2010-04-05 |
2019-11-26 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
ES2731460T3
(es)
|
2010-10-08 |
2019-11-15 |
Harvard College |
Alto rendimiento de células individuales con código de barra
|
WO2012055929A1
(en)
|
2010-10-26 |
2012-05-03 |
Illumina, Inc. |
Sequencing methods
|
ES2615733T3
(es)
|
2010-12-16 |
2017-06-08 |
Gigagen, Inc. |
Métodos para el análisis masivo paralelo de ácidos nucleicos en células individuales
|
GB201106254D0
(en)
|
2011-04-13 |
2011-05-25 |
Frisen Jonas |
Method and product
|
BR112013026199A2
(pt)
|
2011-04-15 |
2017-11-07 |
Compugen Ltd |
polipeptídeo isolado, proteína de fusão, sequência de ácidos nucleicos, vetor de expressão ou um vírus, célula recombinante, método de produção de um polipeptídeo com ectodomínio solúvel lsr, ou seu fragmento ou proteína de fusão, composição farmacêutica, uso de um anticorpo monoclonal ou policlonal ou um seu fragmento de ligação ao antígeno, uso do anticorpo ou do fragmento de ligação ao antígeno, uso de qualquer um de um polipeptídeo isolado, método de regulação por cima de citocinas, indução da expansão de células t, promoção da imunidade de células t específica antigênica e promoção da ativação das células t cd4+ e/ou cd8+ em um sujeito, método para potenciação de uma resposta imune secundária a um antígeno em um paciente, método de uso de pelo menos um de: um polipeptídeo isolado, método para tratamento ou prevenção de uma condição relacionada com o sistema imune, método para tratamento ou prevenção de uma doença infecciosa, método para diagnóstico de uma doença em um sujeito, método de produção de um polipeptídeo com ectodomínio solúvel tmem25, vsig10, ly6g6f, ou seu fragmento ou proteína de fusão, anticorpo monoclonal ou policlonal ou um seu fragmento de ligação ao antígeno, método de imunoterapia em um paciente e método para combinação de vacinação terapêutica com um antígeno em conjunto com a administração de qualquer um de um polipeptídeo
|
EP3789498A1
(en)
|
2011-04-25 |
2021-03-10 |
Bio-rad Laboratories, Inc. |
Methods for nucleic acid analysis
|
ES2797448T3
(es)
|
2011-08-01 |
2020-12-02 |
Bio Rad Laboratories |
Sistema de captura de células
|
CA3104322C
(en)
|
2011-09-23 |
2023-06-13 |
Illumina, Inc. |
Methods and compositions for nucleic acid sequencing
|
US10378051B2
(en)
|
2011-09-29 |
2019-08-13 |
Illumina Cambridge Limited |
Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing
|
BR112014010718B1
(pt)
|
2011-11-16 |
2020-12-22 |
Becton, Dickinson And Company |
métodos, sistemas, dispositivos e kits para detecção de analito em amostra
|
EP2791358B1
(en)
*
|
2011-12-13 |
2017-06-14 |
Single Cell Technology, Inc. |
Method of screening a plurality of single secreting cells for functional activity
|
ES2904816T3
(es)
|
2012-02-27 |
2022-04-06 |
Becton Dickinson Co |
Composiciones para recuento molecular
|
NZ630091A
(en)
|
2012-03-30 |
2016-03-31 |
Ge Healthcare Bio Sciences |
Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample
|
CN102690786B
(zh)
|
2012-06-05 |
2014-02-12 |
武汉格蓝丽富科技有限公司 |
一种细胞富集、分离、提取的方法和仪器及单细胞分析方法
|
CA2881783A1
(en)
|
2012-08-13 |
2014-02-20 |
The Regents Of The University Of California |
Methods and systems for detecting biological components
|
US10584381B2
(en)
|
2012-08-14 |
2020-03-10 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
EP4148118A1
(en)
|
2012-08-24 |
2023-03-15 |
Yale University |
System, device and method for high-throughput multi-plexed detection
|
CA2885839C
(en)
|
2012-09-28 |
2020-11-24 |
Vibrant Holdings, Llc |
Methods, systems, and arrays for biomolecular analysis
|
CN202942869U
(zh)
|
2012-11-07 |
2013-05-22 |
博奥生物有限公司 |
一种微阵列反应装置
|
US9606102B2
(en)
|
2013-01-26 |
2017-03-28 |
Denovo Sciences, Inc. |
System and method for capturing and analyzing cells
|
US20140307931A1
(en)
|
2013-04-15 |
2014-10-16 |
Massachusetts Institute Of Technology |
Fully automated system and method for image segmentation and quality control of protein microarrays
|
US11168115B2
(en)
|
2013-06-20 |
2021-11-09 |
California Institute Of Technology |
Cyclic peptides as protein targeting agents
|
CN109112193A
(zh)
|
2013-07-03 |
2019-01-01 |
伊鲁米那股份有限公司 |
正交合成测序
|
US10112195B2
(en)
|
2013-07-31 |
2018-10-30 |
Hitachi High-Technologies Corporation |
Flow cell for nucleic acid analysis and nucleic acid analyzer
|
GB2546833B
(en)
|
2013-08-28 |
2018-04-18 |
Cellular Res Inc |
Microwell for single cell analysis comprising single cell and single bead oligonucleotide capture labels
|
US9498778B2
(en)
|
2014-11-11 |
2016-11-22 |
Genmark Diagnostics, Inc. |
Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
|
US9824870B1
(en)
|
2014-04-29 |
2017-11-21 |
The United States Of America As Represented By The Administrator Of Nasa |
Portable medical diagnosis instrument
|
WO2016009446A2
(en)
|
2014-07-14 |
2016-01-21 |
Krishnan Venkataramanaa Neelam |
A method for the regeneration and differentiation of human perinephric fat derived mesenchymal stromal cells into astroglial, renal, neuronal and pancreatic progenitor cells
|
US20160108458A1
(en)
*
|
2014-10-06 |
2016-04-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Multiplexed detection and quantification of nucleic acids in single-cells
|
CN106973568B
(zh)
|
2014-10-08 |
2021-07-23 |
诺华股份有限公司 |
预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
|
CN112782140A
(zh)
|
2014-12-03 |
2021-05-11 |
伊索普莱西斯公司 |
细胞分泌特征的分析和筛选
|
CN113698497A
(zh)
|
2014-12-05 |
2021-11-26 |
纪念斯隆-凯特琳癌症中心 |
靶向b-细胞成熟抗原的嵌合抗原受体及其用途
|
WO2016115537A2
(en)
|
2015-01-15 |
2016-07-21 |
Massachusetts Institute Of Technology |
Systems, methods, and apparatus for in vitro single-cell identification and recovery
|
ES2784361T3
(es)
|
2015-01-22 |
2020-09-24 |
Becton Dickinson Co |
Dispositivos y sistemas para la creación de códigos de barras moleculares de dianas de ácido nucleico en células individuales
|
KR20200020997A
(ko)
|
2015-02-10 |
2020-02-26 |
일루미나, 인코포레이티드 |
세포 성분을 분석하기 위한 방법 및 조성물
|
US11353448B2
(en)
|
2015-02-13 |
2022-06-07 |
California Institute Of Technology |
Methods and compositions for quantifying metabolites and proteins from single cells
|
WO2016138496A1
(en)
|
2015-02-27 |
2016-09-01 |
Cellular Research, Inc. |
Spatially addressable molecular barcoding
|
WO2016145409A1
(en)
*
|
2015-03-11 |
2016-09-15 |
The Broad Institute, Inc. |
Genotype and phenotype coupling
|
EP4119677B1
(en)
|
2015-04-10 |
2023-06-28 |
Spatial Transcriptomics AB |
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
|
WO2017124101A2
(en)
|
2016-01-15 |
2017-07-20 |
The Broad Institute Inc. |
Semi-permeable arrays for analyzing biological systems and methods of using same
|
EP3510398A1
(en)
|
2016-09-12 |
2019-07-17 |
Isoplexis Corporation |
System and methods for multiplexed analysis of cellular and other immunotherapeutics
|
DK3538891T3
(da)
|
2016-11-11 |
2022-03-28 |
Isoplexis Corp |
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|
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Isoplexis Corporation |
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|
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Celsee Diagnostics, Inc. |
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|
WO2020117975A1
(en)
|
2018-12-04 |
2020-06-11 |
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|