JP2017519519A5 - - Google Patents
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- Publication number
- JP2017519519A5 JP2017519519A5 JP2017510762A JP2017510762A JP2017519519A5 JP 2017519519 A5 JP2017519519 A5 JP 2017519519A5 JP 2017510762 A JP2017510762 A JP 2017510762A JP 2017510762 A JP2017510762 A JP 2017510762A JP 2017519519 A5 JP2017519519 A5 JP 2017519519A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nicotine demethylase
- mutations
- tobacco plant
- demethylase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14167598.3 | 2014-05-08 | ||
| EP14167598 | 2014-05-08 | ||
| EP14001645 | 2014-05-09 | ||
| EP14001645.2 | 2014-05-09 | ||
| PCT/EP2015/060124 WO2015169927A1 (en) | 2014-05-08 | 2015-05-07 | Reduction of nicotine to nornicotine conversion in plants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519519A JP2017519519A (ja) | 2017-07-20 |
| JP2017519519A5 true JP2017519519A5 (https=) | 2018-06-14 |
| JP6871158B2 JP6871158B2 (ja) | 2021-05-12 |
Family
ID=53276066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017510762A Expired - Fee Related JP6871158B2 (ja) | 2014-05-08 | 2015-05-07 | 植物体におけるニコチンからノルニコチンへの変換の低減 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10415050B2 (https=) |
| EP (1) | EP3140404A1 (https=) |
| JP (1) | JP6871158B2 (https=) |
| KR (1) | KR102442802B1 (https=) |
| CN (1) | CN106459923B (https=) |
| BR (1) | BR112016025234A2 (https=) |
| CA (1) | CA2944965A1 (https=) |
| MX (1) | MX2016014635A (https=) |
| PH (1) | PH12016501718A1 (https=) |
| RU (1) | RU2733837C2 (https=) |
| WO (1) | WO2015169927A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106636146B (zh) * | 2017-02-16 | 2019-09-13 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e5基因突变体及其应用 |
| US11046969B2 (en) * | 2017-05-24 | 2021-06-29 | Epiplanta Biotech Ltd. | Transgenic plant and the method for producing the same |
| US20200140875A1 (en) * | 2017-05-31 | 2020-05-07 | 22Nd Century Limited, Llc | Genome editing methods for producing low-nicotine tobacco products |
| CN111726983B (zh) | 2017-12-07 | 2024-05-07 | 肯塔基大学研究基金会 | bZIP转录因子调节烟碱向降烟碱的转化 |
| CN108192900B (zh) * | 2018-01-16 | 2021-11-30 | 西南大学 | 烟草烟碱去甲基化酶基因cyp82e4的编辑失活载体及其应用 |
| AR115022A1 (es) | 2018-03-28 | 2020-11-18 | Philip Morris Products Sa | Modulación del contenido de aminoácidos en una planta |
| AR115023A1 (es) | 2018-03-28 | 2020-11-18 | Philip Morris Products Sa | Modulación del contenido de azúcar reductor en una planta |
| CN108424921B (zh) * | 2018-04-20 | 2021-04-20 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e10基因错义突变体m594及其应用 |
| EP3827086A1 (en) * | 2018-07-26 | 2021-06-02 | Altria Client Services LLC | Compositions and methods based on pmt engineering for producing tobacco plants and products having altered alkaloid levels |
| GB201812603D0 (en) | 2018-08-02 | 2018-09-19 | British American Tobacco Investments Ltd | Method |
| EP3830251A1 (en) * | 2018-08-02 | 2021-06-09 | Antidote Therapeutics, Inc. | Novel nicotine degrading enzyme variants |
| US11976286B2 (en) | 2018-12-30 | 2024-05-07 | Philip Morris Products S.A. | Modulation of nitrate levels in plants via mutation of nitrate reductase |
| JP2022552638A (ja) | 2019-10-01 | 2022-12-19 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 植物における糖およびアミノ酸含有量の調節（ｓｕｌｔｒ３） |
| JP7659547B2 (ja) | 2019-10-01 | 2025-04-09 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 植物における還元糖含有量の調節（ｉｎｖ） |
| CN114981440A (zh) * | 2019-12-03 | 2022-08-30 | 奥驰亚客户服务有限公司 | 用于产生具有改变的生物碱水平的烟草植物和制品的方法及其组合物 |
| US11331020B2 (en) | 2020-02-06 | 2022-05-17 | Trustees Of Boston University | Enzyme-based electrochemical nicotine biosensor |
| US11536685B2 (en) | 2020-02-06 | 2022-12-27 | Trustees Of Boston University | High throughput assay for identifying microbial redox enzymes |
| JP7210806B2 (ja) * | 2020-04-17 | 2023-01-23 | 日本たばこ産業株式会社 | 低アルカロイド含量のタバコ属植物体およびその製造方法 |
| CN111505158B (zh) * | 2020-05-09 | 2022-09-23 | 云南省烟草农业科学研究院 | 一种基于孵化处理的尼古丁转化烟株色质快速筛查方法 |
| US20240368615A1 (en) | 2021-09-10 | 2024-11-07 | Philip Morris Products S.A. | Modulating alkaloid profiles in nicotiana tabacum |
| CN113980978B (zh) * | 2021-11-22 | 2023-12-26 | 云南中烟工业有限责任公司 | 一种烟草烟碱转运蛋白相关的基因及其应用 |
| WO2023117661A1 (en) | 2021-12-20 | 2023-06-29 | Philip Morris Products S.A. | Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase |
| WO2023117701A1 (en) | 2021-12-21 | 2023-06-29 | Philip Morris Products S.A. | Modulation of nicotine production by alteration of nicotinamidase expression or function in plants |
| CN114540382B (zh) * | 2022-02-18 | 2023-07-18 | 贵州省烟草科学研究院 | 烟草镉转运基因NtPLA1及应用 |
| JP2025533986A (ja) | 2022-10-13 | 2025-10-09 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | Ｎｔｐ２を調節することによって葉バイオマスおよび窒素利用効率を増加させる |
| EP4658670A1 (en) | 2023-02-02 | 2025-12-10 | Philip Morris Products S.A. | Modulation of genes coding for lysine ketoglutarate reductase |
| JP2026506774A (ja) | 2023-02-02 | 2026-02-26 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 糖トランスポーターの調節 |
| CN121335615A (zh) | 2023-06-29 | 2026-01-13 | 菲利普莫里斯生产公司 | 编码谷氨酸脱氢酶的基因的调节 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5810020A (en) | 1993-09-07 | 1998-09-22 | Osmotek, Inc. | Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products |
| US6202649B1 (en) | 1996-12-02 | 2001-03-20 | Regent Court Technologies | Method of treating tobacco to reduce nitrosamine content, and products produced thereby |
| EA002448B1 (ru) | 1997-06-20 | 2002-04-25 | Риджент Корт Текнолоджиз | Способ обработки табака для снижения содержания нитрозоаминов и продукты, полученные этим способом |
| US7700851B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokeless Tobacco Company | Tobacco nicotine demethylase genomic clone and uses thereof |
| EP2338905B1 (en) * | 2005-02-23 | 2017-11-29 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes |
| CA2666383C (en) | 2006-10-13 | 2015-12-22 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes |
| RU2324737C1 (ru) * | 2006-10-18 | 2008-05-20 | Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) | Способ получения трансгенных растений табака с повышенным содержанием пролина |
| US8319011B2 (en) * | 2006-12-15 | 2012-11-27 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
| US8124851B2 (en) * | 2007-11-12 | 2012-02-28 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes |
| PL2231861T3 (pl) | 2007-12-13 | 2015-04-30 | Philip Morris Products Sa | Rośliny transgeniczne modyfikowane w celu zmniejszenia transportu kadmu, produkty pochodne i metody związane |
| US7883371B1 (en) | 2009-07-22 | 2011-02-08 | Hon Hai Precision Ind. Co., Ltd. | Electrical connector with improved contact footprints |
| US9247706B2 (en) | 2010-01-15 | 2016-02-02 | North Carolina State University | Compositions and methods for minimizing nornicotine synthesis in tobacco |
| CN103228671B (zh) | 2010-09-03 | 2017-08-15 | 菲利普莫里斯产品有限公司 | 植物中的重金属减少 |
-
2015
- 2015-05-07 MX MX2016014635A patent/MX2016014635A/es unknown
- 2015-05-07 BR BR112016025234A patent/BR112016025234A2/pt not_active Application Discontinuation
- 2015-05-07 EP EP15726007.6A patent/EP3140404A1/en not_active Withdrawn
- 2015-05-07 WO PCT/EP2015/060124 patent/WO2015169927A1/en not_active Ceased
- 2015-05-07 CA CA2944965A patent/CA2944965A1/en not_active Abandoned
- 2015-05-07 JP JP2017510762A patent/JP6871158B2/ja not_active Expired - Fee Related
- 2015-05-07 US US15/306,172 patent/US10415050B2/en active Active
- 2015-05-07 KR KR1020167031693A patent/KR102442802B1/ko active Active
- 2015-05-07 CN CN201580023352.1A patent/CN106459923B/zh not_active Expired - Fee Related
- 2015-05-07 RU RU2016144409A patent/RU2733837C2/ru active
-
2016
- 2016-09-01 PH PH12016501718A patent/PH12016501718A1/en unknown
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