|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
|
US6177403B1
(en)
|
1996-10-21 |
2001-01-23 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
WO1999061601A2
(en)
|
1998-05-28 |
1999-12-02 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Aav5 vector and uses thereof
|
|
US20030110526A1
(en)
|
1998-08-25 |
2003-06-12 |
Robert H. Brown |
Dysferlin mutations
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
WO2001029243A1
(en)
|
1999-10-15 |
2001-04-26 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
US8202846B2
(en)
|
2000-03-16 |
2012-06-19 |
Cold Spring Harbor Laboratory |
Methods and compositions for RNA interference
|
|
IL151928A0
(en)
|
2000-03-30 |
2003-04-10 |
Whitehead Biomedical Inst |
Rna sequence-specific mediators of rna interference
|
|
US6962815B2
(en)
|
2001-01-05 |
2005-11-08 |
Children's Hopital Inc. |
AAV2 vectors and methods
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
US20050019915A1
(en)
|
2001-06-21 |
2005-01-27 |
Bennett C. Frank |
Antisense modulation of superoxide dismutase 1, soluble expression
|
|
CA2790034A1
(en)
|
2001-06-21 |
2003-01-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
|
CA2452980A1
(en)
|
2001-07-03 |
2003-01-16 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of administering vectors to synaptically connected neurons
|
|
CA2921821A1
(en)
|
2001-07-12 |
2003-01-23 |
University Of Massachusetts |
In vivo production of small interfering rnas that mediate gene silencing
|
|
WO2003006616A2
(en)
|
2001-07-13 |
2003-01-23 |
University Of Iowa Research Foundation |
Pseudotyped adeno-associated viruses and uses thereof
|
|
BR122016004546B8
(pt)
|
2001-11-13 |
2021-07-27 |
Univ Pennsylvania |
vírus adenoassociado recombinante, método de geração do referido vírus e composição compreendendo o referido vírus
|
|
EP3339430A1
(en)
|
2001-12-17 |
2018-06-27 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses thereof
|
|
US20050137153A1
(en)
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
|
AU2003221733A1
(en)
|
2002-04-17 |
2003-11-03 |
University Of Florida Research Foundation, Inc. |
Improved raav vectors
|
|
AU2003221745A1
(en)
|
2002-04-19 |
2003-11-03 |
University Of Florida |
rAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES
|
|
CA2426283C
(en)
|
2002-04-29 |
2006-06-27 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20050255086A1
(en)
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
WO2004014933A1
(en)
|
2002-08-07 |
2004-02-19 |
University Of Massachusetts |
Compositions for rna interference and methods of use thereof
|
|
US7892793B2
(en)
|
2002-11-04 |
2011-02-22 |
University Of Massachusetts |
Allele-specific RNA interference
|
|
EP2314691A3
(en)
|
2002-11-14 |
2012-01-18 |
Dharmacon, Inc. |
Fuctional and hyperfunctional siRNA
|
|
JP4966006B2
(ja)
|
2003-01-28 |
2012-07-04 |
セレクティス |
カスタムメイドメガヌクレアーゼおよびその使用
|
|
US20040219528A1
(en)
|
2003-04-15 |
2004-11-04 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
US7387896B2
(en)
|
2003-03-26 |
2008-06-17 |
The Regents Of The University Of Michigan |
MicroRNA vectors
|
|
US20060228800A1
(en)
|
2003-05-15 |
2006-10-12 |
Shi-Lung Lin |
Novel Transgenic Methods Using intronic RNA
|
|
US7459547B2
(en)
|
2003-06-02 |
2008-12-02 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of RNA silencing
|
|
US7750144B2
(en)
|
2003-06-02 |
2010-07-06 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
|
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
|
CA3072423A1
(en)
|
2003-09-30 |
2005-04-14 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
WO2005062937A2
(en)
|
2003-12-22 |
2005-07-14 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended sirna
|
|
US20060134787A1
(en)
|
2004-12-22 |
2006-06-22 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
|
|
CN103060324B
(zh)
|
2004-03-05 |
2015-04-01 |
贝尼泰克生物制药有限公司 |
用于RNAi试剂同时递送的多启动子表达盒
|
|
WO2005096781A2
(en)
|
2004-04-06 |
2005-10-20 |
University Of Massachusetts |
Methods and compositions for treating gain-of-function disorders using rna interference
|
|
CN101052717A
(zh)
*
|
2004-05-11 |
2007-10-10 |
α基因株式会社 |
诱发rna干扰的多核苷酸以及使用该多核苷酸的基因表达抑制方法
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
NZ555830A
(en)
|
2004-12-15 |
2009-01-31 |
Univ North Carolina |
Chimeric vectors
|
|
WO2006066203A2
(en)
*
|
2004-12-16 |
2006-06-22 |
Alsgen, Llc |
Small interfering rna (sirna) molecules for modulating superoxide dismutase (sod)
|
|
EP1877556B1
(en)
|
2005-03-25 |
2011-09-14 |
Medtronic, Inc. |
Use of anti-tnf or anti-il1 rnai to suppress pro- inflammatory cytokine actions locally to treat pain
|
|
EP3409296A1
(en)
|
2005-04-07 |
2018-12-05 |
The Trustees of the University of Pennsylvania |
Method of increasing the function of an aav vector
|
|
WO2006119432A2
(en)
|
2005-04-29 |
2006-11-09 |
The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services |
Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
|
|
US10000757B2
(en)
|
2005-05-27 |
2018-06-19 |
Ospedale San Raffaele S.R.L. |
Gene vector
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
ATE494372T1
(de)
|
2005-08-29 |
2011-01-15 |
Regulus Therapeutics Inc |
Verfahren für mir-122a-modulation
|
|
EP1979485A2
(en)
|
2006-01-31 |
2008-10-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
CA2642848C
(en)
|
2006-03-03 |
2016-07-12 |
Amorfix Life Sciences Ltd. |
Methods and compositions to treat and detect misfolded-sod1 mediated diseases
|
|
EP2007795B1
(en)
|
2006-03-30 |
2016-11-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid proteins
|
|
EP2799547B1
(en)
|
2006-11-08 |
2016-12-21 |
Veritas Bio, LLC |
In Vivo Delivery of RNA to a Target Cell
|
|
CA2683469C
(en)
|
2007-04-12 |
2019-11-26 |
The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth |
Genetic suppression and replacement
|
|
WO2008147837A1
(en)
|
2007-05-23 |
2008-12-04 |
Dharmacon, Inc. |
Micro-rna scaffolds, non-naturally occurring micro-rnas, and methods for optimizing non-naturally occurring micro-rnas
|
|
AU2008260103B2
(en)
|
2007-05-31 |
2014-04-03 |
University Of Iowa Research Foundation |
Reduction of off-target RNA interference toxicity
|
|
WO2009079592A2
(en)
|
2007-12-17 |
2009-06-25 |
California Institute Of Technology |
Modulating immune system development and function through microrna mir-146
|
|
WO2009102427A2
(en)
*
|
2008-02-11 |
2009-08-20 |
Rxi Pharmaceuticals Corp. |
Modified rnai polynucleotides and uses thereof
|
|
US20090215879A1
(en)
|
2008-02-26 |
2009-08-27 |
University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
EP2268811A1
(en)
|
2008-03-07 |
2011-01-05 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microrna related diseases
|
|
WO2009146178A1
(en)
|
2008-04-15 |
2009-12-03 |
President And Fellows Of Harvard College |
Angiogenin and amyotrophic lateral sclerosis
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
EP2297322A1
(en)
|
2008-06-04 |
2011-03-23 |
The Board of Regents of The University of Texas System |
Modulation of gene expression through endogenous small rna targeting of gene promoters
|
|
WO2009154452A1
(en)
|
2008-06-17 |
2009-12-23 |
Amsterdam Molecular Therapeutics B.V. |
Parvoviral capsid with incorporated Gly-Ala repeat region
|
|
EP2310507A4
(en)
|
2008-07-08 |
2013-03-20 |
David Gladstone Inst |
METHOD AND COMPOSITIONS FOR ANGIOGENIC MODULATION
|
|
WO2010027446A2
(en)
|
2008-09-04 |
2010-03-11 |
Galenea Corp., Et Al. |
Synaptic vesicle cycling assays and systems
|
|
WO2010034314A1
(en)
|
2008-09-24 |
2010-04-01 |
Aarhus Universitet |
Retroviral delivery of synthectic gene cassettes
|
|
WO2010071454A1
(en)
|
2008-12-17 |
2010-06-24 |
Auckland Uniservices Limited |
Adeno-associated viral vectors and uses thereof
|
|
WO2010099383A2
(en)
|
2009-02-26 |
2010-09-02 |
The Johns Hopkins University |
Compositions and methods for ex vivo hepatic nucleic acid delivery
|
|
LT3421603T
(lt)
|
2009-05-02 |
2022-01-10 |
Genzyme Corporation |
Genų terapija, skirta neurodegeneraciniams sutrikimams
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
US20120270930A1
(en)
|
2009-10-29 |
2012-10-25 |
Academisch Ziekenhuis Leiden H.O.D.N. Lumc |
Methods and compositions for dysferlin exon-skipping
|
|
RU2606012C2
(ru)
|
2009-11-09 |
2017-01-10 |
Дженепод Терапевтикс Аб |
Новая вирусная векторная конструкция для нейронспецифического оптимизированного непрерывного синтеза dopa in vivo
|
|
CA2781332C
(en)
|
2009-11-19 |
2018-09-04 |
National University Corporation Okayama University |
System for increasing gene expression and vector comprising the system
|
|
EP2524037B1
(en)
|
2010-01-12 |
2018-05-16 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
|
PT2529020T
(pt)
|
2010-01-28 |
2018-07-30 |
Childrens Hospital Philadelphia |
Plataforma de fabrico escalável para purificação de vetor viral e vetores virais assim purificados para utilização na terapia génica
|
|
WO2011109380A1
(en)
|
2010-03-01 |
2011-09-09 |
The Children's Hospital Of Philadelphia |
Nucleic acids for targeting multiple regions of the hcv genome
|
|
DK2561073T3
(en)
*
|
2010-04-23 |
2016-12-12 |
Univ Massachusetts |
Aav vectors targeted to central nervous system and methods of use thereof
|
|
WO2011133901A2
(en)
|
2010-04-23 |
2011-10-27 |
University Of Massachusetts |
Aav-based treatment of cholesterol-related disorders
|
|
US9546369B2
(en)
|
2010-04-23 |
2017-01-17 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
WO2011135396A1
(en)
*
|
2010-04-30 |
2011-11-03 |
Cellectis |
Method for modulating double-strand break-induced homologous recombination
|
|
US8785413B2
(en)
|
2010-09-27 |
2014-07-22 |
Florida Atlantic University Research Corporation |
Materials and methods for the treatment of pathological neovascularization in the eye
|
|
CA2827380C
(en)
|
2011-02-12 |
2020-08-25 |
University Of Iowa Research Foundation |
Therapeutic nucleic acids
|
|
US20140147418A1
(en)
|
2011-04-15 |
2014-05-29 |
The Us Of America, As Represented By The Secretary Department Of Health And Human Services |
Aav mediated ctla-4 gene transfer to treat sjogren's syndrome
|
|
ES2661680T3
(es)
|
2011-04-21 |
2018-04-03 |
University Of Massachusetts |
Composiciones basadas en VAAr y métodos para tratar deficiencias de alfa-1 anti-tripsina
|
|
US8609088B2
(en)
|
2011-05-10 |
2013-12-17 |
Regents Of The University Of Minnesota |
Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
|
|
US9896729B2
(en)
|
2011-08-31 |
2018-02-20 |
The University Of Manchester |
Method for diagnosing a neurodegenerative disease
|
|
US20140255936A1
(en)
*
|
2011-09-09 |
2014-09-11 |
Mayo Foundation For Medical Education And Research |
Detecting frontotemporal dementia and amyotrophic lateral sclerosis
|
|
CN104011210B
(zh)
|
2011-10-11 |
2018-05-01 |
布里格姆及妇女医院股份有限公司 |
神经退行性病症中的microRNA
|
|
US20130142861A1
(en)
|
2011-12-05 |
2013-06-06 |
National Yang Ming University |
Compositions And Method For Detecting And Treating Abnormal Liver Homeostasis And Hepatocarcinogenesis
|
|
MX367100B
(es)
|
2012-02-17 |
2019-08-05 |
The Children´S Hospital Of Philadelphia |
Composiciones del vector aav y metodos para su transferencia genetica a celulas, organos y tejidos.
|
|
JP6385920B2
(ja)
|
2012-05-09 |
2018-09-05 |
オレゴン ヘルス アンド サイエンス ユニバーシティー |
アデノ随伴ウイルスプラスミド及びベクター
|
|
JP6417322B2
(ja)
*
|
2012-06-21 |
2018-11-07 |
アソシアシオン・アンスティテュ・ドゥ・ミオロジーＡｓｓｏｃｉａｔｉｏｎ Ｉｎｓｔｉｔｕｔ Ｄｅ Ｍｙｏｌｏｇｉｅ |
遺伝子治療ベクターの広範な遺伝子送達
|
|
US10443052B2
(en)
*
|
2012-10-15 |
2019-10-15 |
Ionis Pharmaceuticals, Inc. |
Compositions for modulating C9ORF72 expression
|
|
EP2906697A4
(en)
|
2012-10-15 |
2016-06-22 |
Ionis Pharmaceuticals Inc |
METHOD FOR MONITORING THE C9ORF72 EXPRESSION
|
|
SG11201504523UA
(en)
|
2012-12-12 |
2015-07-30 |
Broad Inst Inc |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
AU2014205134B2
(en)
|
2013-01-14 |
2020-01-16 |
Recombinetics, Inc. |
Hornless livestock
|
|
WO2014114303A1
(en)
|
2013-01-22 |
2014-07-31 |
Deutsches Zentrum Für Neurodegenerative Erkrankungen |
Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
IL298049B2
(en)
|
2013-03-15 |
2023-10-01 |
Univ North Carolina Chapel Hill |
Methods and compounds for ligation of paired AAV glycan vectors
|
|
CN105408352B
(zh)
|
2013-04-18 |
2020-01-14 |
泰莱托恩基金会 |
通过双重aav载体有效递送大基因
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
ES2987399T3
(es)
|
2013-06-05 |
2024-11-14 |
Univ Duke |
Edición génica guiada por ARN y regulación génica
|
|
EP3011031B1
(en)
|
2013-06-17 |
2020-09-30 |
The Broad Institute Inc. |
Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy
|
|
US10155794B2
(en)
|
2013-07-16 |
2018-12-18 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of disorders related to CEP290
|
|
JP6827320B2
(ja)
|
2013-08-05 |
2021-02-10 |
アカデミシュ・ジークンホイス・ライデン・ハー・オー・デー・エン・ライドス・ユニヴェルシタイル・メディシュ・セントルム |
ＬＣＡ−８及び進行性ＲＰを治療するための組換えＡＡＶ−Ｃｒｕｍｂｓホモログ組成物及び方法
|
|
HUE050546T2
(hu)
*
|
2013-08-27 |
2020-12-28 |
Res Inst Nationwide Childrens Hospital |
Termékek és eljárások amiotróf laterálszklerózis kezelésére
|
|
US10221414B2
(en)
*
|
2013-10-11 |
2019-03-05 |
Ionis Pharmaceuticals, Inc. |
Compositions for modulating C9ORF72 expression
|
|
BR112016013547A2
(pt)
|
2013-12-12 |
2017-10-03 |
Broad Inst Inc |
Composições e métodos de uso de sistemas crispr-cas em distúrbios de repetições de nucleotídeos
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
|
US10400227B2
(en)
|
2014-03-17 |
2019-09-03 |
The University Of Manitoba |
β-hexosaminidase protein variants and associated methods for treating GM2 gangliosidoses
|
|
EP3750907A3
(en)
|
2014-03-18 |
2021-04-28 |
University of Massachusetts |
Raav-based compositions and methods for treating amyotrophic lateral sclerosis
|
|
US10975391B2
(en)
|
2014-04-25 |
2021-04-13 |
University Of Massachusetts |
Recombinant AAV vectors useful for reducing immunity against transgene products
|
|
SI3137497T2
(sl)
|
2014-05-02 |
2025-07-31 |
Genzyme Corporation |
Vektorji AAV za gensko terapijo mrežnice in centralnega živčnega sistema
|
|
RU2711147C2
(ru)
|
2014-05-20 |
2020-01-15 |
Юниверсити Оф Айова Рисерч Фаундейшн |
Терапевтические соединения для лечения болезни хантингтона
|
|
WO2015187825A2
(en)
|
2014-06-03 |
2015-12-10 |
University Of Massachusetts |
Compositions and methods for modulating dysferlin expression
|
|
ES2788426T3
(es)
|
2014-06-16 |
2020-10-21 |
Univ Johns Hopkins |
Composiciones y métodos para la expresión de ARNs de guía de CRISPR utilizando el promotor de H1
|
|
EP3174981B1
(en)
|
2014-07-31 |
2020-03-25 |
Association Institut de Myologie |
Treatment of amyotrophic lateral sclerosis
|
|
WO2016054554A1
(en)
|
2014-10-03 |
2016-04-07 |
University Of Massachusetts |
Heterologous targeting peptide grafted aavs
|
|
JP6842410B2
(ja)
|
2014-10-03 |
2021-03-17 |
ユニバーシティ オブ マサチューセッツ |
新規の高効率ライブラリーにより同定されるａａｖベクター
|
|
JP7023108B2
(ja)
|
2014-10-21 |
2022-02-21 |
ユニバーシティ オブ マサチューセッツ |
組み換えａａｖバリアントおよびその使用
|
|
WO2016167780A1
(en)
|
2015-04-16 |
2016-10-20 |
Ionis Pharmaceuticals, Inc. |
Compositions for modulating expression of c9orf72 antisense transcript
|
|
CA3019315A1
(en)
|
2015-04-23 |
2016-10-27 |
University Of Massachusetts |
Modulation of aav vector transgene expression
|
|
US11046955B2
(en)
|
2015-04-24 |
2021-06-29 |
University Of Massachusetts |
Modified AAV constructs and uses thereof
|
|
CA2983364A1
(en)
|
2015-04-27 |
2016-11-03 |
Genethon |
Compositions and methods for the treatment of nucleotide repeat expansion disorders
|
|
US10016514B2
(en)
|
2015-05-15 |
2018-07-10 |
New Hope Research Foundation |
Polynucleotides, vectors and methods for insertion and expression of transgenes
|
|
CN114657180A
(zh)
|
2015-05-16 |
2022-06-24 |
建新公司 |
深内含子突变的基因编辑
|
|
US20180140810A1
(en)
|
2015-06-01 |
2018-05-24 |
University Of Massachusetts |
Catheter assemblies
|
|
WO2016210372A2
(en)
|
2015-06-25 |
2016-12-29 |
University Of Southern California |
Methods to treat neurological diseases
|
|
CA2988471A1
(en)
|
2015-07-28 |
2017-02-02 |
University Of Massachusetts |
Transgenic expression of dnase i in vivo delivered by an adeno-associated virus vector
|
|
US20190000940A1
(en)
|
2015-07-31 |
2019-01-03 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
CA3009308A1
(en)
|
2015-12-23 |
2017-06-29 |
Chad Albert COWAN |
Materials and methods for treatment of amyotrophic lateral sclerosis and/or frontal temporal lobular degeneration
|
|
ES3000677T3
(en)
|
2016-09-30 |
2025-03-03 |
Regeneron Pharma |
Rodents having a hexanucleotide repeat expansion in a c9orf72 locus
|
|
US11859179B2
(en)
|
2017-05-09 |
2024-01-02 |
University Of Massachusetts |
Methods of treating amyotrophic lateral sclerosis (ALS)
|
|
US11739330B2
(en)
|
2017-09-22 |
2023-08-29 |
University Of Massachusetts |
SOD1 dual expression vectors and uses thereof
|