JP2017500879A5 - - Google Patents

Download PDF

Info

Publication number
JP2017500879A5
JP2017500879A5 JP2016544103A JP2016544103A JP2017500879A5 JP 2017500879 A5 JP2017500879 A5 JP 2017500879A5 JP 2016544103 A JP2016544103 A JP 2016544103A JP 2016544103 A JP2016544103 A JP 2016544103A JP 2017500879 A5 JP2017500879 A5 JP 2017500879A5
Authority
JP
Japan
Prior art keywords
amino acid
gram
modified
modification
positive bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016544103A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017500879A (ja
JP6585602B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/069019 external-priority patent/WO2015102814A1/en
Publication of JP2017500879A publication Critical patent/JP2017500879A/ja
Publication of JP2017500879A5 publication Critical patent/JP2017500879A5/ja
Application granted granted Critical
Publication of JP6585602B2 publication Critical patent/JP6585602B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016544103A 2013-12-31 2014-12-08 タンパク質発現の増大 Active JP6585602B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361922613P 2013-12-31 2013-12-31
US61/922,613 2013-12-31
PCT/US2014/069019 WO2015102814A1 (en) 2013-12-31 2014-12-08 Enhanced protein expression

Publications (3)

Publication Number Publication Date
JP2017500879A JP2017500879A (ja) 2017-01-12
JP2017500879A5 true JP2017500879A5 (enExample) 2017-12-28
JP6585602B2 JP6585602B2 (ja) 2019-10-02

Family

ID=52273531

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016544103A Active JP6585602B2 (ja) 2013-12-31 2014-12-08 タンパク質発現の増大

Country Status (8)

Country Link
US (1) US10287591B2 (enExample)
EP (1) EP3089991B1 (enExample)
JP (1) JP6585602B2 (enExample)
CN (1) CN106068273B (enExample)
CA (1) CA2935066C (enExample)
DK (1) DK3089991T3 (enExample)
MX (1) MX2016008595A (enExample)
WO (1) WO2015102814A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106599611B (zh) * 2016-12-09 2019-04-30 中南大学 蛋白质功能标注方法及系统

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302544A (en) 1979-10-15 1981-11-24 University Of Rochester Asporogenous mutant of B. subtilis for use as host component of HV1 system
US4450235A (en) 1982-04-21 1984-05-22 Cpc International Inc. Asporogenic mutant of bacillus subtilis useful as a host in a host-vector system
US5310675A (en) 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
DE3480411D1 (en) 1983-07-06 1989-12-14 Gist Brocades Nv Molecular cloning and expression in industrial microorganism species
US5763257A (en) 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US5264366A (en) 1984-05-29 1993-11-23 Genencor, Inc. Protease deficient bacillus
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
WO1987004461A1 (en) 1986-01-15 1987-07-30 Amgen THERMALLY STABLE AND pH STABLE SUBTILISIN ANALOGS AND METHOD FOR PRODUCTION THEREOF
US4980288A (en) 1986-02-12 1990-12-25 Genex Corporation Subtilisin with increased thermal stability
GB8608194D0 (en) 1986-04-03 1986-05-08 Massey Ferguson Services Nv Valve control system
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
KR0127560B1 (ko) 1987-02-27 1997-12-29 마가렛트 에이.호른 단백질 분해 효소 코드화 유전자의 분자클로닝 및 발현
US4914031A (en) 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
CN1056187C (zh) 1988-02-11 2000-09-06 金克克国际有限公司 新的蛋白水解酶及其在洗涤剂中的应用
US5665587A (en) 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DK97190D0 (da) 1990-04-19 1990-04-19 Novo Nordisk As Oxidationsstabile detergentenzymer
US5482849A (en) 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
ES2121014T3 (es) 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
DE4411223A1 (de) 1994-03-31 1995-10-05 Solvay Enzymes Gmbh & Co Kg Verwendung alkalischer Proteasen in gewerblichen Textilwaschverfahren
AR016969A1 (es) 1997-10-23 2001-08-01 Procter & Gamble VARIANTE DE PROTEASA, ADN, VECTOR DE EXPRESIoN, MICROORGANISMO HUESPED, COMPOSICIoN DE LIMPIEZA, ALIMENTO PARA ANIMALES Y COMPOSICIoN PARA TRATAR UN TEXTIL
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6617148B2 (en) * 2000-06-29 2003-09-09 E. I. Du Pont De Nemours And Company Natural promoters for gene expression and metabolic monitoring in bacillus species
ATE495245T1 (de) * 2002-02-15 2011-01-15 Danisco Us Inc Verbesserte proteinexpression in bacillus subtilis
AU2005308101A1 (en) * 2004-11-26 2006-06-01 Kyowa Hakko Kirin Co., Ltd. Industrially useful microorganism
EP2099818A2 (en) * 2006-11-29 2009-09-16 Novozymes Inc. Bacillus licheniformis chromosome
US20100022861A1 (en) 2008-07-28 2010-01-28 Medtronic, Inc. Implantable optical hemodynamic sensor including an extension member
AR076941A1 (es) 2009-06-11 2011-07-20 Danisco Us Inc Cepa de bacillus para una mayor produccion de proteina

Similar Documents

Publication Publication Date Title
RU2013134401A (ru) Микроорганизм с повышенной продукцией l-аминокислот и способ получения l-аминокислот с его применением
Choi et al. Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements)
CA2900580C (en) Method for producing l-lysine by modifying aconitase gene and/or regulatory elements thereof
WO2014059275A3 (en) Process for producing gougerotin employing streptomyces microflavus strains
CN109810991B (zh) 二氢蝶酸合酶基因folP的用途
JP2022535409A (ja) ラクトバチルスブレビスのγ-アミノ酪酸の合成能を向上させる方法及びその使用
CN103146772B (zh) 用乌头酸酶表达弱化和/或酶活性降低的细菌发酵生产l-赖氨酸的方法
JP6660181B2 (ja) トリコデルマリーセイQM6aおよびその誘導体中の交配障害と関連する遺伝子/遺伝要素ならびにその同定方法
CN103409446A (zh) 一种棒状杆菌基因连续敲除系统及其构建方法和应用
CN107267568A (zh) 利用spoT基因缺失菌株通过发酵生产L‑氨基酸的方法
TWI547558B (zh) 生產l-胺基酸的微生物和使用其的l-胺基酸的生產方法
CN104152483A (zh) argJ基因在发酵生产L-瓜氨酸中的应用
CN112553090B (zh) 一株高产sorbicillinoids的里氏木霉工程菌及其构建方法与应用
JP2017176099A5 (enExample)
JP2017500880A5 (enExample)
CN106636042B (zh) 一种热稳定性和催化活力提高的角蛋白酶突变体
CN103131738B (zh) 用改变乌头酸酶调控元件的细菌发酵生产l-赖氨酸的方法
CN110591993A (zh) 一种基于盐酸刺激的哈维弧菌同源重组基因敲除的方法
Sun et al. Draft genome sequence of Bacillus amyloliquefaciens XK-4-1, a plant growth-promoting endophyte with antifungal activity
Kadam et al. Connecting biology with biotechnology: industrial applications of adaptive laboratory evolution
CN103194439A (zh) 一种工业黄酒酵母单倍体的分离方法
CN103173505A (zh) 用改变乌头酸酶调控元件的细菌发酵生产l-苏氨酸的方法
CN106282219A (zh) 一种稳定、高效的转化野生型克劳氏芽孢杆菌的方法
JP6527669B2 (ja) 枯草菌変異株及びそれを用いたジピコリン酸の製造方法
CN103981230B (zh) 用乌头酸酶表达弱化和/或酶活性降低的细菌发酵生产l-赖氨酸的方法