JP2016517432A5 - - Google Patents
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- JP2016517432A5 JP2016517432A5 JP2016502769A JP2016502769A JP2016517432A5 JP 2016517432 A5 JP2016517432 A5 JP 2016517432A5 JP 2016502769 A JP2016502769 A JP 2016502769A JP 2016502769 A JP2016502769 A JP 2016502769A JP 2016517432 A5 JP2016517432 A5 JP 2016517432A5
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- Japan
- Prior art keywords
- ring
- alkyl
- membered
- phenyl
- membered heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 CCC(CCC(C)C)C*C(C1CCC(*N)CC1)=C Chemical compound CCC(CCC(C)C)C*C(C1CCC(*N)CC1)=C 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790637P | 2013-03-15 | 2013-03-15 | |
| US61/790,637 | 2013-03-15 | ||
| US201361914915P | 2013-12-11 | 2013-12-11 | |
| US61/914,915 | 2013-12-11 | ||
| PCT/US2014/028370 WO2014144100A2 (en) | 2013-03-15 | 2014-03-14 | Sgc stimulators |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017080301A Division JP6267385B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2017080300A Division JP6267384B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2018193191A Division JP6709000B2 (ja) | 2013-03-15 | 2018-10-12 | ｓＧＣ刺激薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016517432A JP2016517432A (ja) | 2016-06-16 |
| JP2016517432A5 true JP2016517432A5 (enExample) | 2017-04-20 |
Family
ID=50513493
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502769A Pending JP2016517432A (ja) | 2013-03-15 | 2014-03-14 | ｓＧＣ刺激薬 |
| JP2017080300A Active JP6267384B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2017080301A Active JP6267385B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2018193191A Active JP6709000B2 (ja) | 2013-03-15 | 2018-10-12 | ｓＧＣ刺激薬 |
| JP2020081703A Active JP7072602B2 (ja) | 2013-03-15 | 2020-05-07 | ｓＧＣ刺激薬 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017080300A Active JP6267384B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2017080301A Active JP6267385B2 (ja) | 2013-03-15 | 2017-04-14 | ｓＧＣ刺激薬 |
| JP2018193191A Active JP6709000B2 (ja) | 2013-03-15 | 2018-10-12 | ｓＧＣ刺激薬 |
| JP2020081703A Active JP7072602B2 (ja) | 2013-03-15 | 2020-05-07 | ｓＧＣ刺激薬 |
Country Status (23)
| Country | Link |
|---|---|
| US (8) | US9481689B2 (enExample) |
| EP (3) | EP3998260B1 (enExample) |
| JP (5) | JP2016517432A (enExample) |
| KR (3) | KR102502937B1 (enExample) |
| CN (5) | CN110016020B (enExample) |
| AU (4) | AU2014227862C1 (enExample) |
| BR (1) | BR112015023349A2 (enExample) |
| CA (1) | CA2907111C (enExample) |
| CY (2) | CY1122919T1 (enExample) |
| DK (2) | DK3660013T3 (enExample) |
| EA (2) | EA033168B1 (enExample) |
| ES (3) | ES2774295T3 (enExample) |
| HR (2) | HRP20220376T1 (enExample) |
| HU (2) | HUE048543T2 (enExample) |
| IL (4) | IL285564B2 (enExample) |
| LT (2) | LT3660013T (enExample) |
| ME (1) | ME03664B (enExample) |
| MX (3) | MX384408B (enExample) |
| PL (2) | PL3660013T3 (enExample) |
| PT (2) | PT3660013T (enExample) |
| RS (2) | RS59981B1 (enExample) |
| SI (2) | SI2970243T1 (enExample) |
| WO (1) | WO2014144100A2 (enExample) |
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| US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| JP6133309B2 (ja) | 2011-10-19 | 2017-05-24 | トゥエルヴ， インコーポレイテッド | 人工心臓弁デバイス |
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| CN103889369B (zh) | 2011-10-19 | 2016-09-14 | 托尔福公司 | 用于心脏瓣膜置换术的装置 |
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| SI2970243T1 (sl) | 2013-03-15 | 2020-04-30 | Cyclerion Therapeutics, Inc. | SGC stimulatorji |
| CN105246431B (zh) | 2013-05-20 | 2018-04-06 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
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| CA2961489A1 (en) | 2014-09-17 | 2016-03-24 | Glen Robert RENNIE | Sgc stimulators |
| RS60906B1 (sr) | 2014-10-06 | 2020-11-30 | Vertex Pharma | Modulatori regulatora transmembranske provodljivosti za cističnu fibrozu |
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| KR102513343B1 (ko) | 2016-07-07 | 2023-03-22 | 사이클리온 테라퓨틱스, 인크. | sGC 자극제의 인 전구약물 |
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| EA038096B1 (ru) * | 2016-09-23 | 2021-07-06 | Сайклерион Терапьютикс, Инк. | ПРИМЕНЕНИЕ СТИМУЛЯТОРОВ sGC ДЛЯ ЛЕЧЕНИЯ НЕАЛКОГОЛЬНОГО СТЕАТОГЕПАТИТА (NASH) |
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| WO2018069148A1 (de) | 2016-10-11 | 2018-04-19 | Bayer Pharma Aktiengesellschaft | Kombination enthaltend sgc aktivatoren und mineralocorticoid-rezeptor-antagonisten |
| JP7101688B2 (ja) | 2016-10-11 | 2022-07-15 | バイエル・ファルマ・アクティエンゲゼルシャフト | ｓＧＣ刺激薬とミネラルコルチコイド受容体拮抗薬とを含む組み合わせ |
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| PT3551622T (pt) | 2016-12-09 | 2020-11-12 | Vertex Pharma | Modulador do regulador da condutância transmembrana da fibrose quística, composições farmacêuticas, métodos de tratamento e processo de fabrico do modulador |
| US20190381039A1 (en) | 2016-12-13 | 2019-12-19 | Cyclerion Therapeutics, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF ESOPHAGEAL MOTILITY DISORDERS |
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| US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
| US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
| US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
| US11253509B2 (en) | 2017-06-08 | 2022-02-22 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
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